专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明公开

EP0850411A1 ELECTRODE 失效
标题翻译：电极
公开(公告)号：EP0850411A1
公开(公告)日：1998-07-01
申请号：EP96924551.0
申请日：1996-07-16
申请人： CYGNUS, INC.
发明人： KURNIK, Ronald, T. , TAMADA, Janet , TIERNEY, Michael
IPC分类号： G01N27
CPC分类号： G01N27/3272
摘要： An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which assembly includes a scavenging electrode is disclosed. The electrode of the invention is comprised of 1) a working electrode; 2) a scavenging electrode; and 3) an electrically insulating gap defined by adjacent edges of 1) and 2) and electrically isolating 1) and 2). The scavenging electrode substantially reduces or eliminates 'edge-effects' or error in signal transported to the working electrode via a path which includes a radial vector component, i.e., eliminates chemical signal other than that which moves to the catalytic surface of the working electrode via a path which is substantially perpendicular to catalytic surface of the working electrode.
摘要翻译：公开了一种用于感测从源扩散到工作电极的电化学信号的电极组件，该组件包括扫气电极。本发明的电极由1）工作电极组成; 2）扫气电极; 和3）由1）和2）的相邻边缘限定的电绝缘间隙并且电隔离1）和2）。清除电极基本上减少或消除了经由包括径向矢量分量的路径传送到工作电极的信号中的“边缘效应”或误差，即，消除除了移动到工作电极的催化表面的化学信号之外的化学信号基本垂直于工作电极的催化表面的路径。

42. 发明授权

EP0515566B1 ULTRASOUND ENHANCED DELIVERY OF MATERIALS THROUGH SKIN 失效转让
标题翻译：，材料通过皮肤使用超声增强的递送
公开(公告)号：EP0515566B1
公开(公告)日：1997-01-22
申请号：EP91905678.8
申请日：1991-02-21
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , CYGNUS, INC.
发明人： BOMMANNAN, Durairaj , OKUYAMA, Hirohisa , GUY, Richard, Henry , STAUFFER, Paul , FLYNN, Gordon, L.
IPC分类号： A61M37/00 , A61B19/00
CPC分类号： A61N7/02 , A61B10/00 , A61B10/0045 , A61B10/02 , A61B2017/00765 , A61K9/0009 , A61M37/0092 , A61M2037/0007 , A61N1/30 , A61N7/00
摘要： A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultrasound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.

43. 发明授权

EP0400078B1 PRINTED TRANSDERMAL DRUG DELIVERY DEVICE 有权转让
标题翻译：离子注入透皮给药中药安排。
公开(公告)号：EP0400078B1
公开(公告)日：1995-09-06
申请号：EP89903404.5
申请日：1989-02-10
申请人： CYGNUS, INC.
发明人： MIRANDA, Jesus , CLEARY, Gary , W.
IPC分类号： A61F13/02 , A61F13/00
CPC分类号： A61K9/7084 , A61F2013/0296
摘要： A method for making transdermal drug delivery devices (10) is provided which includes: laminating an absorbent source layer (13) to a pressure-sensitive, pharmaceutically acceptable contact adhesive (14); depositing a drug in liquid form on one face of the source layer (13); laminating an anchor adhesive layer (12) to the opposing face of the source layer (13); and applying a drug-impermeable backing layer (11) to the anchor adhesive (12), which backing layer (11) then defines the upper surface of the device. The invention also encompasses transdermal drug delivery devices having a source layer (13) in contact with and contained between anchor (12) and contact adhesive layers (14), with a backing layer (11) adjacent the anchor adhesive (12) defining the upper surface of the device.

44. 发明授权

EP1077636B1 SIGNAL PROCESSING FOR MEASUREMENT OF PHYSIOLOGICAL ANALYTES 有权
标题翻译：信号处理测量生理分析物
公开(公告)号：EP1077636B1
公开(公告)日：2004-01-21
申请号：EP99922953.7
申请日：1999-05-11
申请人： CYGNUS, INC.
发明人： BERNER, Bret , DUNN, Timothy, C. , FARINAS, Kathleen, C. , GARRISON, Michael, D. , KURNIK, Ronald, T. , LESHO, Matthew, J. , POTTS, Russell, O. , TAMADA, Janet , TIERNEY, Michael, J.
IPC分类号： A61B5/00
CPC分类号： A61B5/1477 , A61B5/14532 , A61B5/14542 , A61B5/1486 , G06F19/00
摘要： A method is provided for continually or continuously measuring the concentration of target chemical analytes present in a biological system, and processing analyte-specific signals to obtain a measurement value that is closely correlated with the concentration of the target chemical analyte in the biological system. One important application of the invention involves a method for signal processing in a system for monitoring blood glucose values.

45. 发明授权

EP1077634B1 MONITORING OF PHYSIOLOGICAL ANALYTES 有权
标题翻译：监测分析物生理学
公开(公告)号：EP1077634B1
公开(公告)日：2003-07-30
申请号：EP99921908.2
申请日：1999-05-11
申请人： CYGNUS, INC.
发明人： BERNER, Bret , CHIANG, Chia-Ming , GARRISON, Michael, D. , JONA, Jana , POTTS, Russell, O. , TAMADA, Janet , TIERNEY, Michael, J.
IPC分类号： A61B5/00 , A61N1/30
CPC分类号： A61B5/1486 , A61B5/14532 , A61B5/150022 , A61B5/150091 , A61B5/157 , A61N1/30 , C12Q1/006
摘要： Methods and devices are provided for measuring the concentration of target chemical analytes present in a biological system. Device configuration and/or measurement techniques are employed in order to reduce the effect of interfering species on sensor sensitivity. One important application of the invention involves a method and device for monitoring blood glucose values.

46. 发明授权

EP0942278B1 Biosensor, iontophoretic sampling system and methods of use thereof 有权
标题翻译：生物传感器电离子透入采样系统及其应用方法
公开(公告)号：EP0942278B1
公开(公告)日：2002-06-12
申请号：EP99301887.8
申请日：1999-03-12
申请人： CYGNUS, INC.
发明人： Kim, Lynn , Parris, Norman A. , Potts, Russell O. , Tamada, Janet A. , Tierney, Michael J.
IPC分类号： G01N27/327 , C12Q1/00 , C12Q1/54 , C12M1/40 , A61N1/30
CPC分类号： A61B5/14514 , A61B5/14532 , A61B5/1486 , A61B5/1495 , A61N1/30

47. 发明公开

EP1102561A1 PRESS DEVICE FOR A GEL/SENSOR ASSEMBLY 有权
标题翻译：打印设备凝胶/传感器单元
公开(公告)号：EP1102561A1
公开(公告)日：2001-05-30
申请号：EP99969004.3
申请日：1999-09-17
申请人： CYGNUS, INC.
发明人： BUTLER, Michael, J. , CONN, Thomas, E. , LIU, David, M. , PARRIS, Norman, A. , REIDY, Michael , SONI, Pravin
IPC分类号： A61B5/0408
CPC分类号： A61B5/1486 , A61B5/04087 , A61B5/14514 , A61B5/1468 , A61B2562/0215 , A61B2562/0217 , Y10S439/909
摘要： Devices and methods are described for improving the contact of a conductive material, for example, a hydrogel, with a sensor, for example an electrode, by means of using mechanical force to apply the conductive material to the sensor before use of the conductive material and sensor in a sampling device. The device and methods of the present invention improve the sensor response characteristics in transdermal sampling devices placed in operative contact with a skin or mucosal surface of a biological system to obtain a chemical signal associated with an analyte of interest.

48. 发明公开

EP0848608A2 SUPERSATURATED TRANSDERMAL DRUG DELIVERY SYSTEMS, AND METHODS FOR MANUFACTURING THE SAME 有权转让
标题翻译：过饱和透皮给药系统和方法及其
公开(公告)号：EP0848608A2
公开(公告)日：1998-06-24
申请号：EP96930735.0
申请日：1996-09-06
申请人： CYGNUS, INC.
发明人： FARINAS, Kathleen, C. , MILLER, Chad, M. , SONI, Pravin, L.
IPC分类号： A61K9 , A61K47
CPC分类号： A61K9/7061 , A61K9/7053 , A61K9/7069
摘要： Methods are provided for manufacturing transdermal drug delivery systems containing supersaturated drug reservoirs, such that higher drug fluxes are obtained. The methods involve heating the drug reservoir components to a predetermined temperature. Generally, this temperature is higher than the depressed melting temperature of the polymer-drug admixture which will serve as the drug reservoir. In an alternative embodiment, wherein heat treatment of the reservoir components results in a system having two liquid phases, the predetermined temperature is calculated so as to be higher than the melting temperature of the pure drug. Drug reservoirs and novel transdermal delivery systems prepared using the disclosed techniques are provided as well.

49. 发明公开

EP0812150A1 CONTINUOUS MONITORING OF PHYSIOLOGICAL ANALYTE 失效
标题翻译：连续监测生理样品组分
公开(公告)号：EP0812150A1
公开(公告)日：1997-12-17
申请号：EP96945019.0
申请日：1996-12-20
申请人： CYGNUS, INC.
发明人： KURNIK, Ronald, T. , TAMADA, Janet , TIERNEY, Michael , POTTS, Russell, Owen
IPC分类号： A61B5
CPC分类号： A61B5/14532
摘要： A method for continual monitoring of a physiologic analyte in a subject includes steps of contacting the subject with a collection reservoir such that the analyte can move from the subject into the collection reservoir, the contents of the collection reservoir being in operative communication with a detector, collecting the analyte in the collection reservoir, using the detector to detect the analyte in the collection reservoir, and, once the analyte has been detected, rendering the analyte undetectable by the detector. Also, apparatus for continual monitoring of a physiologic analyte in a subject includes a collection reservoir for receiving the analyte from the subject, the contents of the collection reservoir being in operative relationship with a detector that detects the analyte in the reservoir, and means for rendering the analyte, once detected, undetectable by the reservoir.

50. 发明公开

EP0766579A1 PULSATILE DELIVERY SYSTEMS OF BIOLOGICALLY ACTIVE AGENTS USING ELECTRO VOLTAGE PULSING FOR CONTROLLING MEMBRANE PERMEABILITY 失效
标题翻译：电力脉动BENÜTZENDEN生理活性物质，用于控制膜的渗透供应系统
公开(公告)号：EP0766579A1
公开(公告)日：1997-04-09
申请号：EP95925294.0
申请日：1995-06-23
申请人： CYGNUS, INC.
发明人： WONG, Ooi , CHEN, Tung-Fen , POTTS, Russell O. , BOMMANNAN, Durairaj Bommi
IPC分类号： A61N1
CPC分类号： A61N1/0412 , A61N1/0428 , A61N1/325 , A61N1/327
摘要： The invention relates to a method for pulsed transport of a substance through tissue, the method comprising the steps of: (a) applying at least one electrical pulse to the tissue causes electroporation of the tissue region, the electrical pulse being applied for an electroporation pulse duration, the electroporation pulse duration being shorter than the driving force duration; (b) applying a driving force to the region of tissue whereby the driving force causes the substance to be transported through the tissue for a driving force duration; and (c) repeating step (a) during the driving force duration.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式