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    • 40. 发明公开
    • 나노물질 위해성 분석 장치, 분석 방법 및 이를 이용한 나노물질의 약물 효과 측정 장치 및 그 시스템
    • 用于分析纳米材料的毒性的装置和方法以及使用其测量药物纳米材料的效果的装置和系统
    • KR1020100083987A
    • 2010-07-23
    • KR1020090003356
    • 2009-01-15
    • 한국과학기술원
    • 서태석최종영
    • C12Q1/02G01N33/15G01N33/50B82Y5/00
    • B01L3/502769B01L2300/0867B01L2300/0883G01N33/5008
    • PURPOSE: A system and apparatus for measuring drug effect of nano substance by an apparatus and method for analyzing harmfulness of nano substance are provided to analyze/evaluate harfulness in real time. CONSTITUTION: An apparatus for analyzing harmfulness of nano substance comprises: a first injection unit(100a,100b) which sequentially injecting solution containing cells and nano substance; a microchannel mixing unit(110) for mixing injected nano substance and dividing in a plurality of microchannels; a plurality of chambers(120) for capturing single cells from the solution containing cell of the plural microchannels; and a second injection unit for injecting a material for measuring cell change. A method for analyzing harmfulness of nano substance comprises: a step of injecting solution containing cells; a step of capturing plural single cells from the solution; a step of reacting nano substance of different concentration to plural single cells; and a step of injecting the material for measuring cell change into plural single cells.
    • 目的:提供一种用于分析纳米物质有害性的仪器和方法来测量纳米物质药效的系统和装置,用于实时分析/评价有害物质。 构成:用于分析纳米物质有害性的装置包括:顺序地注入含有细胞和纳米物质的溶液的第一注射单元(100a,100b); 用于混合注入的纳米物质并在多个微通道中分割的微通道混合单元(110); 多个腔室(120),用于从多个微通道的溶液容纳单元捕获单个细胞; 以及用于注入用于测量电池变化的材料的第二注射单元。 一种用于分析纳米物质有害性的方法包括:注入含有细胞的溶液的步骤; 从解决方案捕获多个单个细胞的步骤; 使不同浓度的纳米物质与多个单细胞反应的步骤; 以及将用于测量电池变化的材料注入多个单电池的步骤。