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31. 发明申请

WO2005074838B1 Injector for intraocular lens system 审中-公开
标题翻译：注射器用于眼内透镜系统
公开(公告)号：WO2005074838B1
公开(公告)日：2006-05-18
申请号：PCT/US2005002871
申请日：2005-02-01
申请人： VISIOGEN INC , TSAI GEORGE
发明人： TSAI GEORGE
IPC分类号： A61F2/16
CPC分类号： A61F2/1678 , A61F2/1648 , A61F2/1662 , A61F2/167
摘要： Disclosed is an injector (100) which comprises an injector housing (102) having a longitudinal axis (A-A) and an injection probe disposed along the longitudinal axis. The injector further comprises an intraocular lens (200) disposed in the housing. The intraocular lens comprises first and second interconnected viewing elements (202, 204), and the optical axes of the first and second viewing elements are substantially aligned. The optical axes are substantially orthogonal to the longitudinal axis of the housing. The injector further comprises a lens carrier (104) which engages one of the viewing elements. The viewing elements are moveable in response to longitudinal movement of the lens carrier relative to the injector housing. The longitudinal movement causes both (i) the optical axes to be displaced relative to each other and (ii) the viewing elements to be disposed substantially on the longitudinal axis of the injector housing.
摘要翻译：公开了一种喷射器（100），其包括具有纵向轴线（A-A）和沿纵向轴线设置的喷射探针的喷射器壳体（102）。注射器还包括设置在壳体中的眼内透镜（200）。眼内透镜包括第一和第二互连的观察元件（202,204），并且第一和第二观察元件的光轴基本对准。光轴基本上垂直于壳体的纵向轴线。喷射器还包括接合其中一个观察元件的透镜托架（104）。响应于透镜支架相对于注射器壳体的纵向移动，观察元件可移动。纵向移动导致（i）光轴相对于彼此移位，并且（ii）观察元件基本上设置在注射器壳体的纵向轴线上。

32. 发明申请

WO2009114428A1 METHOD AND DEVICE FOR INSERTING AN INTRAOCULAR LENS 审中-公开
标题翻译：插入眼科镜片的方法和装置
公开(公告)号：WO2009114428A1
公开(公告)日：2009-09-17
申请号：PCT/US2009/036404
申请日：2009-03-06
申请人： VISIOGEN, INC. , TSAI, George , NGUYEN, Tuan, Anh , NGUYEN, Phu, H. , EVANS, Scott
发明人： TSAI, George , NGUYEN, Tuan, Anh , NGUYEN, Phu, H. , EVANS, Scott
IPC分类号： A61F2/16
CPC分类号： A61F2/1675 , A61F2/1629 , A61F2/1648 , A61F2/1678 , A61F2002/1683 , A61F2250/0021 , A61F2250/0025
摘要： An injector (900) for inserting an intraocular lens (930, 980) into an eye includes a lumen (910). The lumen (910, 960) can include a terminal portion (912, 962) at a distal end (916, 966) and a proximal portion (914, 964) juxtaposed with the terminal portion (912, 962). An injector plunger (920, 970) can be disposed within the lumen (910, 960) for generating a driving force (944, 994) on the intraocular lens (930, 980). The injector (900) can include a lens frictional force (942) that has a first value when the lens (930, 980) is at a first location (Ll) within the proximal portion (914, 964) and a second value when the lens (930, 980) is a,t a second location (L2) within the terminal portion (912, 962). The first value can be smaller than the second value.
摘要翻译：用于将眼内透镜（930,980）插入眼睛的注射器（900）包括内腔（910）。管腔（910,960）可以包括在远端（916,966）处的端子部分（912，962）和与端子部分（912,962）并置的近端部分（914,964）。注射器柱塞（920,970）可以设置在内腔（910,960）内，用于在眼内透镜（930,980）上产生驱动力（944,944）。注射器（900）可以包括透镜摩擦力（942），当透镜（930,980）位于近端部分（914,964）内的第一位置（L1）时具有第一值，并且当第透镜（930,980）是端子部分（912,962）内的第二位置（L2）。第一个值可以小于第二个值。

33. 发明申请

WO2007016533A9 ACCOMMODATING INTRAOCULAR LENS SYSTEM WITH ABERRATION-ENHANCED PERFORMANCE 审中-公开
标题翻译：具有增强性能的住院镜片系统
公开(公告)号：WO2007016533A9
公开(公告)日：2007-07-12
申请号：PCT/US2006029852
申请日：2006-07-31
申请人： VISIOGEN INC , NGUYEN TUAN ANH , ZADNO-AZIZI GHOLAM-REZA , EVANS SCOTT , PORTNEY VALDEMAR
发明人： NGUYEN TUAN ANH , ZADNO-AZIZI GHOLAM-REZA , EVANS SCOTT , PORTNEY VALDEMAR
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1627 , A61F2/1629 , A61F2/1632 , A61F2/1648
摘要： An accommodating intraocular lens (100) implantable in an eye. The lens comprises an anterior portion having an anterior biasing element and an anterior optic having refractive power (106). The lens further comprises a posterior portion having a posterior biasing element and a posterior optic having refractive power (118). The anterior optic and the posterior optic are relatively moveable in response to action of the ciliary muscle to change the separation between the optics and the refractive power of the lens. The lens has an aberration-inducing force characteristic of about 70 mg to about 115 mg to allow aberration-inducing relative movement of the optics when the lens is in the eye, thereby adding optical aberration to the lens which increases depth of focus of the lens. In one variation, the lens has an aberration-inducing force characteristic of 70 mg to 115 mg. Related methods are also disclosed.
摘要翻译：一种可植入眼睛的适应性眼内透镜（100）。透镜包括具有前偏置元件的前部和具有屈光力的前光学元件（106）。透镜还包括具有后偏置元件的后部部分和具有屈光力的后光学元件（118）。前视神经和后视镜相对于睫状肌的作用相对移动以改变光学元件与透镜屈光力之间的分离。透镜具有约70mg至约115mg的像差诱导力特征，以允许当透镜在眼睛中时像差引起的光学元件的相对运动，从而增加透镜的光学像差，从而增加透镜的焦深的光学像差。在一个变型中，透镜具有70mg至115mg的像差诱导力特征。还公开了相关方法。

34. 发明申请

WO2007016533A3 ACCOMMODATING INTRAOCULAR LENS SYSTEM WITH ABERRATION-ENHANCED PERFORMANCE 审中-公开
公开(公告)号：WO2007016533A3
公开(公告)日：2007-02-08
申请号：PCT/US2006/029852
申请日：2006-07-31
申请人： VISIOGEN, INC. , NGUYEN, Tuan, Anh , ZADNO-AZIZI, Gholam-Reza , EVANS, Scott , PORTNEY, Valdemar
发明人： NGUYEN, Tuan, Anh , ZADNO-AZIZI, Gholam-Reza , EVANS, Scott , PORTNEY, Valdemar
IPC分类号： A61F2/16
摘要： An accommodating intraocular lens (100) implantable in an eye. The lens comprises an anterior portion having an anterior biasing element and an anterior optic having refractive power (106). The lens further comprises a posterior portion having a posterior biasing element and a posterior optic having refractive power (118). The anterior optic and the posterior optic are relatively moveable in response to action of the ciliary muscle to change the separation between the optics and the refractive power of the lens. The lens has an aberration-inducing force characteristic of about 70 mg to about 115 mg to allow aberration-inducing relative movement of the optics when the lens is in the eye, thereby adding optical aberration to the lens which increases depth of focus of the lens. In one variation, the lens has an aberration-inducing force characteristic of 70 mg to 115 mg. Related methods are also disclosed.

35. 发明申请

WO2004073560A9 METHOD AND DEVICE FOR COMPACTING AN INTRAOCULAR LENS 审中-公开
标题翻译：用于压迫眼内透镜的方法和装置
公开(公告)号：WO2004073560A9
公开(公告)日：2004-10-14
申请号：PCT/US2004004033
申请日：2004-02-11
申请人： VISIOGEN INC , AYTON IAN , EVANS SCOTT , NGUYEN TUAN
发明人： EVANS SCOTT , NGUYEN TUAN
IPC分类号： A61F2/16
CPC分类号： A61F2/1678 , A61F2/1648 , A61F2250/0021
摘要： Disclosed is an apparatus for compacting an intraocular lens. The apparatus comprises a lens compactor having a first configuration for retaining the intraocular lens in an unstressed condition and a second configuration in which the compactor stresses the lens into an at least partially compacted condition without advancing the lens along an injection axis of the compactor. The compactor accomplishes this by applying a compacting force in a direction generally orthogonal to the optical axis of the lens. The compactor is responsive to a compactor actuator that is movable by a user to change the compactor from the first configuration to the second configuration. Additional apparatus and methods are disclosed as well.
摘要翻译：公开了一种用于压紧人工晶状体的装置。该设备包括具有用于将人工晶状体保持在未受力状态的第一构造的透镜压缩器和其中压实器将透镜压缩到至少部分压实状态而不使压缩器沿着压实器的注射轴线前进的第二构造。压实机通过在大致垂直于透镜光轴的方向上施加压实力来实现这一点。压实机响应于压实机致动器，该压实机致动器可由使用者移动以将压实机从第一构造变为第二构造。另外的设备和方法也被公开。

36. 发明专利

CA2752046C COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS 未知
公开(公告)号：CA2752046C
公开(公告)日：2017-04-18
申请号：CA2752046
申请日：2010-02-11
申请人： VISIOGEN INC
发明人： LIAO XIUGAO
IPC分类号： C08F220/18
摘要： Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyl-dialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.

37. 发明专利

CA2718420C METHOD AND DEVICE FOR INSERTING AN INTRAOCULAR LENS 未知
公开(公告)号：CA2718420C
公开(公告)日：2016-10-11
申请号：CA2718420
申请日：2009-03-06
申请人： VISIOGEN INC
发明人： TSAI GEORGE , NGUYEN TUAN ANH , NGUYEN PHU H , EVANS SCOTT
IPC分类号： A61F2/16
摘要： An injector (900) for inserting an intraocular lens (930, 980) into an eye includes a lumen (910). The lumen (910, 960) can include a terminal portion (912, 962) at a distal end (916, 966) and a proximal portion (914, 964) juxtaposed with the terminal portion (912, 962). An injector plunger (920, 970) can be disposed within the lumen (910, 960) for generating a driving force (944, 994) on the intraocular lens (930, 980). The injector (900) can include a lens frictional force (942) that has a first value when the lens (930, 980) is at a first location (L1) within the proximal portion (914, 964) and a second value when the lens (930, 980) is a,t a second location (L2) within the terminal portion (912, 962). The first value can be smaller than the second value.

38. 发明专利

CA2515909C METHOD AND DEVICE FOR COMPACTING AN INTRAOCULAR LENS 未知
公开(公告)号：CA2515909C
公开(公告)日：2012-03-20
申请号：CA2515909
申请日：2004-02-11
申请人： VISIOGEN INC
发明人： EVANS SCOTT , NGUYEN TUAN , AYTON IAN
IPC分类号： A61F2/16
摘要： Disclosed is an apparatus for compacting an intraocular lens. The apparatus comprises a lens compactor having a first configuration for retaining the intraocular lens in an unstressed condition and a second configuration in which the compactor stresses the lens into an at least partially compacted condition without advancing the lens along an injection axis of the compactor. The compactor accomplishes this by applying a compacting force in a direction generally orthogonal to the optical axis of the lens. The compactor is responsive to a compactor actuator that is movable by a user to change the compactor from the first configuration to the second configuration. Additional apparatus and methods are disclosed as well.

39. 发明专利

AU2010213730A1 Copolymers for intraocular lens systems 未知
公开(公告)号：AU2010213730A1
公开(公告)日：2011-09-01
申请号：AU2010213730
申请日：2010-02-11
申请人： VISIOGEN INC
发明人： XIUGAO LIAO
IPC分类号： C08F220/18
摘要： Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.

40. 发明专利

DE602005022552D1 INJEKTOR FÜR EIN INTRAOKULARES LINSENSYSTEM 未知
公开(公告)号：DE602005022552D1
公开(公告)日：2010-09-09
申请号：DE602005022552
申请日：2005-02-01
申请人： VISIOGEN INC
发明人： TSAI GEORGE
IPC分类号： A61F2/16

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