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31. 发明申请

US20110224609A1 Alignment of a Needle in an Intradermal Injection Device 审中-公开
标题翻译：针头在皮内注射装置中的对准
公开(公告)号：US20110224609A1
公开(公告)日：2011-09-15
申请号：US13057006
申请日：2009-12-07
申请人： Izrail Tsals , Darrell Harvey
发明人： Izrail Tsals , Darrell Harvey
IPC分类号： A61M5/46
CPC分类号： A61M5/3287 , A61M5/3216 , A61M5/425 , A61M5/46
摘要： An adapter device (100, 200) for use in combination with a syringe (20) to form an assembly (10) for delivering an intradermal injection. The adapter device comprises a body (110, 210) which is connectable to the syringe. A second primary skin contacting surface (232) is positioned at a distal end (126, 226) of the body. At least one support element (140, 150, 240) is connected to the body. With the assembly in an assembled condition, the at least one support element supports a needle cannula (24) connected to the syringe. The needle cannula is supported by the at least one support element intermediate a base (26) and a tip (28) of the needle cannula. At least a terminal portion of the needle cannula extends axially in a direction substantially parallel to at least a planar portion of the second primary skin contacting surface.
摘要翻译：一种用于与注射器（20）组合使用以形成用于输送皮内注射的组件（10）的适配器装置（100,200）。适配器装置包括可连接到注射器的本体（110,210）。第二主要皮肤接触表面（232）位于身体的远端（126,226）。至少一个支撑元件（140,150,240）连接到主体。在组装在组装状态下，至少一个支撑元件支撑连接到注射器的针插管（24）。所述针管由所述针插管的基部（26）和尖端（28）中间的所述至少一个支撑元件支撑。针套管的至少一个末端部分沿与第二主要皮肤接触表面的至少平面部分基本平行的方向轴向延伸。

32. 发明申请

US20070112310A1 Injecting apparatus 有权
标题翻译：注射装置
公开(公告)号：US20070112310A1
公开(公告)日：2007-05-17
申请号：US10566333
申请日：2004-07-28
申请人： Gilad Lavi , Izrail Tsals
发明人： Gilad Lavi , Izrail Tsals
IPC分类号： A61M5/00
CPC分类号： A61M5/2033 , A61M5/3157 , A61M5/3202 , A61M5/326 , A61M5/3271 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/2418 , A61M2005/3247 , A61M2205/581 , A61M2205/582
摘要： An injector is automatic in that the needle is inserted into the injection site (e.g., a patient's skin) with user or caregiver assistance, the delivery is automatically initiated upon needle insertion, and the needle is retracted automatically after the end of delivery. Preferably the needle is not seen by the user prior to, during or after injection. Prior to and after injection, the needle is hidden in the device so as to avoid any potential injury or health risk to the user or health care provider. The injector includes a housing and a shield arranged to slide relative to the housing and a driver moving during drug delivery. The housing and shield form a cartridge enclosure. The cartridge is shielded and locked after delivery is completed. A needle-locking mechanism can be used in any number of pen-like injectors or safety needles.
摘要翻译：注射器是自动的，因为用户或照顾者帮助将针插入注射部位（例如，患者的皮肤），在针插入时自动启动输送，并且在递送结束后针自动缩回。优选地，在注射之前，期间或之后使用者看不到针。在注射之前和之后，针头隐藏在设备中，以避免对使用者或医疗保健提供者造成任何潜在的伤害或健康风险。注射器包括壳体和屏蔽件，其布置成相对于壳体滑动并且驱动器在药物递送期间移动。外壳和屏蔽形成盒式磁带。送货完成后，盒式屏蔽和锁定。针状锁定机构可用于任何数量的笔式注射器或安全针。

33. 发明申请

US20130006189A1 ASSEMBLY FOR USE WITH A SYRINGE 有权
标题翻译：装配与SYRINGE一起使用
公开(公告)号：US20130006189A1
公开(公告)日：2013-01-03
申请号：US13583096
申请日：2011-03-11
申请人： Izrail Tsals , Christopher Evans , Brian Costello
发明人： Izrail Tsals , Christopher Evans , Brian Costello
IPC分类号： A61M5/32
CPC分类号： A61M5/425 , A61M5/158 , A61M5/24 , A61M5/3287 , A61M5/46 , A61M2005/1585
摘要： An assembly for use with a syringe having a barrel and a needle includes a sealing element surrounding and positioned over at least a portion of the distal end of the syringe. An adapter at least partially surrounds the sealing element and is positioned over the distal end of the syringe. The adapter has a first skin contacting surface positioned at a distal end thereof. At least a portion of the first skin contacting surface extends generally parallel to at least a terminal end of the needle. The adapter also has a second skin contacting surface positioned proximally relative to the terminal end of the needle and at an angle to the first skin contacting surface. A needle shield at least partially surrounds and is removably positioned over at least one of the adapter, the sealing element and the syringe barrel.
摘要翻译：用于具有镜筒和针头的注射器的组件包括围绕并定位在注射器的远端的至少一部分上方的密封元件。适配器至少部分地围绕密封元件并且被定位在注射器的远端上方。适配器具有位于其远端处的第一皮肤接触表面。第一皮肤接触表面的至少一部分大致平行于针的至少末端延伸。适配器还具有相对于针的终端向近侧定位并与第一皮肤接触表面成一定角度的第二皮肤接触表面。针护罩至少部分地围绕并且可移除地定位在适配器，密封元件和注射器筒中的至少一个上。

34. 发明授权

US07717877B2 Injecting apparatus 有权
标题翻译：注射装置
公开(公告)号：US07717877B2
公开(公告)日：2010-05-18
申请号：US10566333
申请日：2004-07-28
申请人： Gilad Lavi , Izrail Tsals
发明人： Gilad Lavi , Izrail Tsals
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/2033 , A61M5/3157 , A61M5/3202 , A61M5/326 , A61M5/3271 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/2418 , A61M2005/3247 , A61M2205/581 , A61M2205/582
摘要： An injector is automatic in that the needle is inserted into the injection site (e.g., a patient's skin) with user or caregiver assistance, the delivery is automatically initiated upon needle insertion, and the needle is retracted automatically after the end of delivery. Preferably the needle is not seen by the user prior to, during or after injection. Prior to and after injection, the needle is hidden in the device so as to avoid any potential injury or health risk to the user or health care provider. The injector includes a housing and a shield arranged to slide relative to the housing and a driver moving during drug delivery. The housing and shield form a cartridge enclosure. The cartridge is shielded and locked after delivery is completed. A needle-locking mechanism can be used in any number of pen-like injectors or safety needles.
摘要翻译：注射器是自动的，因为用户或照顾者帮助将针插入注射部位（例如，患者的皮肤），在针插入时自动启动输送，并且在递送结束后针自动缩回。优选地，在注射之前，期间或之后使用者看不到针。在注射之前和之后，针头隐藏在设备中，以避免对使用者或医疗保健提供者造成任何潜在的伤害或健康风险。注射器包括壳体和屏蔽件，其布置成相对于壳体滑动并且驱动器在药物递送期间移动。外壳和屏蔽形成盒式磁带。送货完成后，盒式屏蔽和锁定。针状锁定机构可用于任何数量的笔式注射器或安全针。

35. 发明授权

US09327086B2 Needle shield and adapter fixedly attached to syringe 有权
标题翻译：针头护罩和适配器固定在注射器上
公开(公告)号：US09327086B2
公开(公告)日：2016-05-03
申请号：US13583096
申请日：2011-03-11
申请人： Izrail Tsals , Christopher Evans , Brian Costello
发明人： Izrail Tsals , Christopher Evans , Brian Costello
IPC分类号： A61M5/46 , A61M5/42 , A61M5/24 , A61M5/158 , A61M5/32
CPC分类号： A61M5/425 , A61M5/158 , A61M5/24 , A61M5/3287 , A61M5/46 , A61M2005/1585
摘要： An assembly for use with a syringe having a barrel and a needle includes a sealing element surrounding and positioned over at least a portion of the distal end of the syringe. An adapter at least partially surrounds the sealing element and is positioned over the distal end of the syringe. The adapter has a first skin contacting surface positioned at a distal end thereof. At least a portion of the first skin contacting surface extends generally parallel to at least a terminal end of the needle. The adapter also has a second skin contacting surface positioned proximally relative to the terminal end of the needle and at an angle to the first skin contacting surface. A needle shield at least partially surrounds and is removably positioned over at least one of the adapter, the sealing element and the syringe barrel.
摘要翻译：用于具有镜筒和针头的注射器的组件包括围绕并定位在注射器的远端的至少一部分上方的密封元件。适配器至少部分地围绕密封元件并且被定位在注射器的远端上方。适配器具有位于其远端处的第一皮肤接触表面。第一皮肤接触表面的至少一部分大致平行于针的至少末端延伸。适配器还具有相对于针的终端向近侧定位并与第一皮肤接触表面成一定角度的第二皮肤接触表面。针护罩至少部分地围绕并且可移除地定位在适配器，密封元件和注射器筒中的至少一个上。

36. 发明授权

US08556861B2 Methods and devices for intradermal injection 有权
标题翻译：用于皮内注射的方法和装置
公开(公告)号：US08556861B2
公开(公告)日：2013-10-15
申请号：US12597103
申请日：2008-04-23
申请人： Izrail Tsals
发明人： Izrail Tsals
IPC分类号： A61M5/00
CPC分类号： A61M5/46 , A61M5/3243 , A61M5/3271 , A61M5/3287 , A61M5/425 , A61M2005/3247
摘要： Devices and methods for intradermal (ID) administration of diagnostic and therapeutic agents, vaccines and other compounds into the dermal layer of the skin are disclosed. The devices and the methods simplify the ID injection process and increase the consistency of the placement of the needle tip in the dermal space close to the skin surface allowing for a shallow cannula placement in the dermis. Furthermore, the devices and methods broaden the number of sites suitable for ID injection and make the ID injection possible with limited training.
摘要翻译：公开了将皮肤（ID）给予皮肤真皮层中的诊断和治疗剂，疫苗和其它化合物的装置和方法。装置和方法简化了ID注射过程，并且增加了针尖靠近皮肤表面的皮肤空间中的放置位置的一致性，从而允许在真皮中放置浅插管。此外，设备和方法扩大了适用于ID注入的站点数量，并且可以通过有限的培训进行ID注入。

37. 发明申请

US20120191065A1 INTRADERMAL PEN ADAPTER 有权
标题翻译： INTRADERMAL PEN适配器
公开(公告)号：US20120191065A1
公开(公告)日：2012-07-26
申请号：US13355031
申请日：2012-01-20
申请人： Izrail Tsals , Christopher Evans , Brian Costello
发明人： Izrail Tsals , Christopher Evans , Brian Costello
IPC分类号： A61M5/32
CPC分类号： A61M5/46 , A61B5/150068 , A61B5/150183 , A61B5/150748 , A61B5/153 , A61M5/158 , A61M5/3287
摘要： An intradermal injection adapter includes a body having a longitudinal axis and a central portion located distally relative to the body along the longitudinal axis. The central portion has a cannula channel therethrough extending generally parallel to the longitudinal axis. A cannula within the cannula channel has a sharpened tip for injection into a patient and a sharpened opposite proximal end for injection into a pen injector. A distal protrusion has a first skin contacting surface extending generally parallel to the longitudinal axis. The first skin contacting surface is spaced from the cannula such that a distal portion of the cannula extends generally parallel to the first skin contacting surface.
摘要翻译：真皮内注射适配器包括具有纵向轴线的主体和沿着纵向轴线相对于身体向远侧定位的中心部分。中心部分具有大致平行于纵向轴线的插管通道。插管通道内的插管具有用于注入患者的尖锐尖端和用于注入笔式注射器的锐化的相对近端。远端突起具有大致平行于纵向轴线延伸的第一皮肤接触表面。第一皮肤接触表面与套管间隔开，使得套管的远端部分大致平行于第一皮肤接触表面延伸。

38. 发明申请

US20060229569A1 Syringe with automatically triggered safety sleeve 有权
标题翻译：注射器自动触发安全套
公开(公告)号：US20060229569A1
公开(公告)日：2006-10-12
申请号：US10566226
申请日：2004-07-28
申请人： Gilad Lavi , Izrail Tsals
发明人： Gilad Lavi , Izrail Tsals
IPC分类号： A61M5/32 , A61M5/00
CPC分类号： A61M5/326 , A61M5/3202 , A61M5/3271 , A61M2005/3109 , A61M2005/3247 , A61M2205/581 , A61M2205/582
摘要： A medical injection device is provided which includes a shield system and a syringe. The shield system includes a housing, a shield telescopically received in the housing slidably coupled to the housing and a driver that pushes the syringe stopper to cause drug injection. The driver is equipped with sensing elements that automatically detect empty syringe. A spring resiliently urges the shield from a retracted position to an extended position shielding the needle. The syringe is coupled to the housing. The shield is positioned externally to the syringe and the driver. The shield includes flexible latches to keep its position relative to the housing during storage and use. The axial movement of the driver in respect to the syringe causes an automatic release of the spring by sensors when the syringe is empty, allowing the spring to move and lock the shield in the extended position after use.
摘要翻译：提供了包括屏蔽系统和注射器的医疗注射装置。屏蔽系统包括壳体，可伸缩地容纳在壳体中可滑动地联接到壳体的壳体和推动注射器塞子以引起药物注射的驱动器。驾驶员配备有自动检测空针筒的传感元件。弹簧弹性地将屏蔽件从缩回位置推向屏蔽针的延伸位置。注射器联接到壳体。护罩位于注射器和驱动器的外部。屏蔽包括弹性闩锁，以在存储和使用期间保持其相对于壳体的位置。驾驶员相对于注射器的轴向运动导致当注射器为空时由传感器自动释放弹簧，允许弹簧在使用后将其移动并锁定在延伸位置。

39. 发明申请

US20120123386A1 INTRADERMAL INJECTION ADAPTER 有权
标题翻译：肠内注射适配器
公开(公告)号：US20120123386A1
公开(公告)日：2012-05-17
申请号：US13386099
申请日：2010-07-23
申请人： Izrail Tsals
发明人： Izrail Tsals
IPC分类号： A61M5/31 , A61M5/32
CPC分类号： A61M5/46 , A61M5/321 , A61M5/3216 , A61M5/3287
摘要： An intradermal injection assembly for injecting a medicament into skin could form an intradermal needle with an adapter, an intradermal syringe with an adapter or an adapter for a merger with a syringe with a cannula. The intradermal adapter in these devices has a body having a longitudinal axis, a central portion having a cannula channel and a distal protrusion extending generally parallel to the longitudinal axis. The distal protrusion of the adapter has a first skin contacting surface extending generally parallel to the longitudinal axis. At least a portion of the distal protrusion is generally transparent such that the portion of the cannula that extends distally relative to a demarcation plane can be viewed through the distal protrusion during insertion of the cannula into a patient's skin.
摘要翻译：用于将药物注射到皮肤中的真皮内注射组件可以形成具有适配器的皮内针，具有适配器的皮内注射器或用于与具有套管的注射器并入的适配器。这些装置中的真皮内适配器具有具有纵向轴线的主体，具有套管通道的中心部分和大致平行于纵向轴线延伸的远端突出部。适配器的远端突起具有大致平行于纵向轴线延伸的第一皮肤接触表面。远侧突起的至少一部分通常是透明的，使得在将插管插入患者皮肤期间，可以通过远侧突出部分观察到相对于分界平面向远侧延伸的套管部分。

40. 发明申请

US20100137831A1 METHODS AND DEVICES FOR INTRADERMAL INJECTION 有权
标题翻译：用于入射注射的方法和装置
公开(公告)号：US20100137831A1
公开(公告)日：2010-06-03
申请号：US12597103
申请日：2008-04-23
申请人： Izrail Tsals
发明人： Izrail Tsals
IPC分类号： A61M5/31
CPC分类号： A61M5/46 , A61M5/3243 , A61M5/3271 , A61M5/3287 , A61M5/425 , A61M2005/3247
摘要： Devices and methods for intradermal (ID) administration of diagnostic and therapeutic agents, vaccines and other compounds into the dermal layer of the skin are disclosed. The devices and the methods simplify the ID injection process and increase the consistency of the placement of the needle tip in the dermal space close to the skin surface allowing for a shallow cannula placement in the dermis. Furthermore, the devices and methods broaden the number of sites suitable for ID injection and make the ID injection possible with limited training.
摘要翻译：公开了将皮肤（ID）给予皮肤真皮层中的诊断和治疗剂，疫苗和其它化合物的装置和方法。装置和方法简化了ID注射过程，并且增加了针尖靠近皮肤表面的皮肤空间中的放置位置的一致性，从而允许在真皮中放置浅插管。此外，设备和方法扩大了适用于ID注入的站点数量，并且可以通过有限的培训进行ID注入。

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