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31. 发明申请

WO2009019358A1 PROCÉDÉ DE DÉPÔT D'UNE SUSPENSION CELLULAIRE SUR UNE PLAQUE D'ANALYSE 审中-公开
标题翻译：在分析板上沉积细胞悬浮液的方法
公开(公告)号：WO2009019358A1
公开(公告)日：2009-02-12
申请号：PCT/FR2008/051231
申请日：2008-07-02
申请人： NOVACYT , PELTIER, Eric
发明人： PELTIER, Eric
IPC分类号： G01G1/38 , G01N1/28
CPC分类号： G01N1/38 , B01L3/5085 , B01L2200/026 , B01L2200/0642 , B01L2300/069 , B01L2300/0829 , G01N1/2813 , G01N2035/1032 , G01N2035/1058
摘要： Ce procédé comprend au moins les étapes successives suivantes : prélever un premier volume (V3) de liquide de mélange (3), prévoir un premier volume (V4) d'air sous le premier volume (V3) de liquide de mélange (3), prélever un deuxième volume (V5) de liquide de mélange (3), prélever un volume (V6) de suspension cellulaire (4), la suspension cellulaire (4) montant à la surface du deuxième volume (V5) de liquide de mélange (3), imprimer un mouvement de va et vient aux liquides présents dans la pipette (1 ) de sorte que le premier volume (V4) d'air est comblé et que le premier et le deuxième volumes (V3, V5) de liquide de mélange (3) et le volume (V6) de suspension cellulaire (4) se mélangent, déposer la suspension cellulaire (6) obtenue sur la plaque d'analyse (8).
摘要翻译：本发明的方法至少包括以下连续步骤：对混合液体（3）的第一体积（V3）进行取样; 在混合液体（3）的第一体积（V3）下方提供第一空气体积（V4）; 对混合液体（3）的第二体积（V5）进行取样; 对细胞悬浮液（4）的体积（V6）进行取样，将细胞悬浮液（4）上升到混合液体（3）的第二体积（V5）的表面; 对移液器（1）中的液体进行往复运动，使得第一空气体积（V4）被填充，使得混合液体（3）的第一和第二体积（V3，V5）和体积（V6）将细胞悬浮液（4）混合; 以及将如此获得的细胞悬浮液（6）沉积在分析板（8）上。

32. 发明申请

WO2008104710A2 TRAY FOR CARRYING A PLURALITY OF BOTTLES 审中-公开
标题翻译：携带多种血糖的托盘
公开(公告)号：WO2008104710A2
公开(公告)日：2008-09-04
申请号：PCT/FR2008050232
申请日：2008-02-13
申请人： NOVACYT , PELTIER ERIC
发明人： PELTIER ERIC
CPC分类号： B01L9/06 , B01L3/5082 , G01N35/026
摘要： The invention relates to a tray for carrying at least one bottle (4) that has to be positioned and held precisely on said tray, said tray comprising a support (5) on which the bottle (4) is intended to be placed, at least two rails (6) running substantially parallel to one another along the support (5), said rails comprising at least one shoulder (11) extending above the support (5) toward the other rail (6) so that a lower edge (12) of the bottle (4) can fit between and be immobilized in said rails in a longitudinal or transverse direction and in an upwards direction, each rail (6) having at least one imprint (13), said imprints being positioned facing one another, each imprint (13) being designed to accommodate an immobilizing means (14) provided on the bottle (4) so that the bottle (4) can be immobilized in the rails (6) in a longitudinal or transverse direction. The invention also relates to a bottle used with a tray such as this.
摘要翻译：本发明涉及一种托盘，用于承载至少一个必须定位并且精确地保持在所述托盘上的瓶子（4），所述托盘包括一个支架（5），所述瓶子（4）将被放置在其上，至少两个轨道（6）沿着支撑件（5）彼此基本平行地延伸，所述轨道包括至少一个在支撑件（5）上方朝着另一轨道（6）延伸的肩部（11），使得下边缘（12）瓶子（4）可以在纵向或横向方向上并且沿向上的方向装配在所述轨道中并且被固定在所述轨道中，每个轨道（6）具有至少一个压印（13），所述压印物彼此相对定位，每个压印（13）被设计成容纳设置在瓶子（4）上的固定装置（14），使得瓶子（4）能够在纵向或横向上固定在轨道（6）中。本发明还涉及一种与诸如此类的托盘一起使用的瓶子。

33. 发明申请

WO2008015325A3 SYSTEM FOR DEPOSITING CELLS ON AN ASSAY PLATE 审中-公开
标题翻译：用于在分析板上沉积细胞的系统
公开(公告)号：WO2008015325A3
公开(公告)日：2008-03-20
申请号：PCT/FR2007001228
申请日：2007-07-17
申请人： NOVACYT , PELTIER ERIC
发明人： PELTIER ERIC
IPC分类号： G01N1/28
CPC分类号： G01N1/2813 , G01N2001/2826 , G01N2001/2846
摘要： This system, comprising a chamber (5) for receiving a cellular suspension, the open bottom of which extends opposite a deposition area of the plate and is in communication with a fixative-absorbing material (7) disposed around the deposition area and held in position by being clamped between two parts (3, 6) associated with means (9, 10) for fastening them to each other, one of which (6) is associated with the receiving chamber (5) while the other (3) is associated with the plate, is characterized in that the fastening means (9, 10) are connected to means (11) for controlling the clamping pressure so as to vary the latter over time between a first high pressure (P1), at the beginning of the deposition, and a second, less high pressure (P2).
摘要翻译：该系统包括用于接收细胞悬浮液的腔室（5），所述腔室的开放底部与所述板的沉积区域相对地延伸并且与设置在沉积区域周围并保持在适当位置的固定吸收材料（7）通过夹紧在与用于将它们彼此紧固在一起的装置（9,10）相关联的两个部分（3,6）之间，其中一个（6）与容纳室（5）相关联，而另一个（3）与板的特征在于，紧固装置（9,10）连接到用于控制夹紧压力的装置（11），以便在沉积开始时在第一高压（P1）与第一高压，第二个较低压力（P2）。

34. 发明授权

US09261439B2 Cell deposition system 有权
标题翻译：细胞沉积系统
公开(公告)号：US09261439B2
公开(公告)日：2016-02-16
申请号：US13357868
申请日：2012-01-25
申请人： Eric Roger Louis Peltier
发明人： Eric Roger Louis Peltier
IPC分类号： C12M1/34 , C12M3/00 , G01N1/28 , B01L3/00
CPC分类号： G01N1/2813 , B01L3/502 , B01L2200/0621 , B01L2200/0668 , B01L2300/069 , B01L2400/0633 , G01N2001/2826 , G01N2001/2846
摘要： A system for depositing cells on an analysis plate, the cells being contained in a cell suspension including a fixing agent and the cells, included, for receiving the suspension, a chamber (5) which is positioned above the analysis plate and whose base is open and extends opposite a cell depositing zone of the plate and a material for absorbing the fixing agent placed around the chamber and the depositing zone of the plate. The chamber is mounted so as to be able to be moved between a first position in abutment against the analysis plate in order to allow the cells to be deposited on the depositing zone of the plate via decantation and a second position remote from this analysis plate in order to place the chamber in a fluid relationship with the absorption material in order to allow this material to absorb the fixing agent.
摘要翻译：一种用于在分析板上沉积细胞的系统，所述细胞包含在包括固定剂和细胞的细胞悬浮液中，包括用于接收悬浮液的细胞，位于分析板上方并且其基部开放的腔室（5）并且与板的电池沉积区相对延伸，并且用于吸收放置在板的周围的室和沉积区周围的固定剂的材料。该室被安装成能够在与分析板邻接的第一位置之间移动，以便允许通过倾析将电池沉积在板的沉积区上，并且远离该分析板的第二位置以使腔室与吸收材料形成流体关系，以允许该材料吸收固定剂。

35. 发明授权

US08478018B2 Method for sample cell analysis using a virtual analysis plate 有权
标题翻译：使用虚拟分析板进行样本细胞分析的方法
公开(公告)号：US08478018B2
公开(公告)日：2013-07-02
申请号：US12995089
申请日：2009-05-29
申请人： Eric Peltier
发明人： Eric Peltier
IPC分类号： G06K9/00 , C12N5/00 , G01N33/554
CPC分类号： G06T7/0012 , G02B21/365 , G06K9/00127 , G06T2207/10056 , G06T2207/10064 , G06T2207/30024
摘要： A method includes carrying out at least a first processing of a sample (2), the processing being adapted to mark pathological cells among the sample cells; and carrying out several image acquisitions of the sample (2) provided on an analysis plate (6) in order to obtain images each representing an area of the analysis plate (6) wherein the images set side by side define an image (20) of the entire sample. The method further includes automatically running all the acquired images of the sample (2) on a display at a predetermined running speed, the speed being adapted for enabling an observer to analyze the image and to determine if the represented sample area includes potentially pathological cells or not; and stopping the running if at least one abnormality is detected that may indicate the presence of a pathological cell.
摘要翻译：一种方法包括进行样品（2）的至少第一处理，所述处理适于标记样品池中的病理细胞; 并对分析板（6）上提供的样品（2）进行几次图像采集，以获得各自表示分析板（6）的区域的图像，其中并排设置的图像限定图像（20），整个样品。该方法还包括以预定的运行速度在显示器上自动地运行样品（2）的所有获取的图像，该速度适于使得观察者能够分析图像并且确定所示出的样本区域是否包括潜在的病理细胞或不; 并且如果检测到至少一个可能指示存在病理细胞的异常，则停止运行。

36. 发明申请

US20130059330A1 FIXING SOLUTION FOR BIOLOGICAL CELLS 审中-公开
标题翻译：生物细胞固定溶液
公开(公告)号：US20130059330A1
公开(公告)日：2013-03-07
申请号：US13575325
申请日：2011-01-20
申请人： Eric Peltier
发明人： Eric Peltier
IPC分类号： G01N1/30
CPC分类号： A01N1/02 , A01N1/0231 , G01N1/30
摘要： This fixing solution is intended to preserve in vitro a cytological sample, comprising nucleated cells and erythrocytes and comprises alcohol for fixing the cells. It comprises physiological saline in order to avoid osmotic shocks at the wall of the cells, formalin and polyethylene glycol for retaining the size and the integrity of the nucleated cells and erythrocytes, which are fixed in said solution.The solution does not contain acetone or any compounds of the ketone or acetic acid family.
摘要翻译：该固定溶液旨在在体外保留包含有核细胞和红细胞的细胞学样品，并且包含用于固定细胞的醇。它包括生理盐水，以避免在细胞壁上的渗透冲击，福尔马林和聚乙二醇，用于保持固定在所述溶液中的有核细胞和红细胞的大小和完整性。该溶液不含有丙酮或酮或乙酸族的任何化合物。

37. 发明申请

US20110262907A1 PROCECURE FOR PREPARING A PROCESSED VIRTUAL ANALYSIS IMAGE 审中-公开
标题翻译：处理虚拟分析图像的过程
公开(公告)号：US20110262907A1
公开(公告)日：2011-10-27
申请号：US13126650
申请日：2009-10-28
申请人： Eric Peltier
发明人： Eric Peltier
IPC分类号： C12Q1/68 , C12Q1/02
CPC分类号： G02B21/367 , G01N1/30 , G01N33/569
摘要： This method includes the following steps: carrying out a processing of the specimen so as to make it possible to differentiate the pathological cells from the healthy cells of the specimen; and performing an acquisition of images of the specimen disposed on an analysis plate so as to obtain a plurality of images each representing a zone of the analysis plate, the images placed side by side forming an image of the whole of the specimen so as to create a virtual analysis plate. The method furthermore includes the following step: performing on the virtual analysis plate a processing of the images acquired so as to obtain a virtual restitution of the colors and of the intensity of the colors of the cytoplasm and/or of the nucleus, the colors and the intensity being able to be modified according to the preferences of the person in charge of the analysis.
摘要翻译：该方法包括以下步骤：进行样本的处理，以使病理细胞与样本的健康细胞分化; 并且执行对设置在分析板上的样本的图像的获取，以便获得各自表示分析板的区域的多个图像，并排地形成形成整个样本的图像的图像，以便产生一个虚拟分析板。该方法还包括以下步骤：在虚拟分析板上执行所获取的图像的处理，以便获得颜色和细胞质和/或核的颜色的强度的虚拟恢复，颜色和强度可以根据分析负责人的偏好进行修改。

38. 发明申请

US20100089925A1 TRAY FOR CARRYING A PLURALITY OF FLASKS 有权
标题翻译：携带大量浮标的纸盘
公开(公告)号：US20100089925A1
公开(公告)日：2010-04-15
申请号：US12527254
申请日：2008-02-13
申请人： Eric Peltier
发明人： Eric Peltier
IPC分类号： B65D41/04 , A47F7/00
CPC分类号： B01L9/06 , B01L3/5082 , G01N35/026
摘要： A tray for carrying at least one bottle that has to be positioned and held precisely on the tray, includes a support on which the bottle is intended to be placed, at least two rails running substantially parallel to one another along the support, the rails including at least one shoulder extending above the support toward the other rail so that a lower edge of the bottle can fit between and be immobilized in the rails in a longitudinal or transverse direction and in an upwards direction, each rail having at least one imprint, the imprints being positioned facing one another, each imprint being designed to accommodate an immobilizing element provided on the bottle so that the bottle can be immobilized in the rails in a longitudinal or transverse direction. A bottle used with a tray such as this is also described.
摘要翻译：用于承载至少一个必须定位并且精确地保持在托盘上的瓶子的托盘包括一个支撑件，瓶子要被放置在该支架上，至少两个轨道沿支撑件彼此基本平行地延伸，轨道包括至少一个肩部，其延伸到支撑件上方朝向另一个导轨，使得瓶子的下边缘可以在纵向或横向方向上并且沿向上的方向装配在轨道中并且被固定在轨道中，每个轨道具有至少一个压印，印记被定位成彼此面对，每个印记被设计成容纳设置在瓶子上的固定元件，使得瓶子可以沿纵向或横向固定在轨道中。还描述了与这样的托盘一起使用的瓶子。

39. 发明授权

US10240183B2 Method and apparatus for preparing a cellular container comprising means for pre-analysis of a sample that has been taken 有权
公开(公告)号：US10240183B2
公开(公告)日：2019-03-26
申请号：US14911017
申请日：2014-08-08
申请人： NOVACYT
发明人： Eric Peltier
IPC分类号： C12Q1/24 , G01N1/14 , G01N9/24 , G01N21/59 , G01N9/00 , G01N35/10
摘要： A method for preparing a cell suspension for analysis includes at least: taking a sample of the cell suspension using a pipetting-dispensing device, which includes at least one pipe, and depositing the sample present in the pipetting-dispensing device in an analysis container. Between the taking of the sample and the depositing, the method includes at least one pre-analysis of the sample, which is carried out by a pre-analysis device placed on the pipe of the pipetting-dispensing device.

40. 发明授权

US08460208B2 Flask for preparing a cytological suspension based on a fixing solution 有权
标题翻译：烧瓶用于基于固定溶液制备细胞学悬浮液
公开(公告)号：US08460208B2
公开(公告)日：2013-06-11
申请号：US13357127
申请日：2012-01-24
申请人： Eric Peltier
发明人： Eric Peltier
IPC分类号： A61B10/00 , B01D24/00 , B01D35/24 , B01D24/38 , C12M1/34
CPC分类号： A61B10/0096 , A61B2010/0216
摘要： A system for preparing a cytological suspension is based on a fixing solution. The system containing a cytological sample-taking brush and a flask having an opening for receiving the cytological sample-taking brush are detachably fastened to a handle including a brush-receiving filter basket that is at least partially immersed in the a suspension.
摘要翻译：用于制备细胞学悬浮液的系统基于定影液。包含细胞学取样刷和具有用于接收细胞学取样刷的开口的烧瓶的系统可拆卸地紧固到包括至少部分浸没在悬浮液中的刷接收过滤篮的手柄。

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