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31. 发明授权

US08557529B2 Nanopore capture system 有权
标题翻译：纳米捕获系统
公开(公告)号：US08557529B2
公开(公告)日：2013-10-15
申请号：US12757433
申请日：2010-04-09
申请人： Stanislav Polonsky , Ali Afzali-Ardakani , Hongbo Peng , Gustavo A. Stolovitzky , Ajay A. Royyuru , Mark N. Wegman
发明人： Stanislav Polonsky , Ali Afzali-Ardakani , Hongbo Peng , Gustavo A. Stolovitzky , Ajay A. Royyuru , Mark N. Wegman
IPC分类号： C12Q1/68
CPC分类号： G01N33/48721 , G01N33/54373
摘要： A nanopore capture system may include a material configured to pass through a nanopore device in a controlled manner based upon its interaction with the nanopore device. The system may also include a capture mechanism connected to one end of the material. The capture mechanism may be configured to catch a particular type of molecule while ignoring other types of molecules. The system may also include a controller to manipulate and/or detect the particular type of molecule.
摘要翻译：纳米孔捕获系统可以包括配置为基于其与纳米孔装置的相互作用以受控方式穿过纳米孔装置的材料。系统还可以包括连接到材料的一端的捕获机构。捕获机制可以被配置为捕获特定类型的分子，同时忽略其它类型的分子。该系统还可以包括操纵和/或检测特定类型的分子的控制器。

32. 发明申请

US20130043131A1 TRAPPING MOLECULAR SEGMENTS IN NANO-GAPS 失效
标题翻译：在纳米GAPS中捕获分子部分
公开(公告)号：US20130043131A1
公开(公告)日：2013-02-21
申请号：US13209582
申请日：2011-08-15
申请人： Venkat S.K. Balagurusamy , Stanislav Polonsky
发明人： Venkat S.K. Balagurusamy , Stanislav Polonsky
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： G01N27/447 , G01N33/48721
摘要： A molecule trapping method includes forming a fluid bridge between a first reservoir and a second reservoir, translocating a molecule from the first reservoir to the second reservoir through the fluid bridge, detecting when a segment of the molecule is in the fluid bridge, breaking the fluid bridge and forming an a gap between the first and the second reservoirs, thereby trapping a segment of the molecule in the gap and making measurements on the segment of the molecule.
摘要翻译：分子俘获方法包括在第一储存器和第二储存器之间形成流体桥，通过流体桥将分子从第一储存器转移到第二储存器，检测分子何时位于流体桥中，破坏流体并且在第一和第二储层之间形成间隙，从而将分子的一段捕获在间隙中并对分子的区段进行测量。

33. 发明授权

US08354336B2 Forming an electrode having reduced corrosion and water decomposition on surface using an organic protective layer 失效
标题翻译：使用有机保护层形成表面上具有降低的腐蚀和水分解的电极
公开(公告)号：US08354336B2
公开(公告)日：2013-01-15
申请号：US12820543
申请日：2010-06-22
申请人： Ali Afzali-Ardakani , Shafaat Ahmed , Hariklia Deligianni , Dario L. Goldfarb , Stefan Harrer , Binquan Luan , Glenn J. Martyna , Hongbo Peng , Stanislav Polonsky , Stephen Rossnagel , Xiaoyan Shao , Gustavo A. Stolovitzky
发明人： Ali Afzali-Ardakani , Shafaat Ahmed , Hariklia Deligianni , Dario L. Goldfarb , Stefan Harrer , Binquan Luan , Glenn J. Martyna , Hongbo Peng , Stanislav Polonsky , Stephen Rossnagel , Xiaoyan Shao , Gustavo A. Stolovitzky
IPC分类号： H01L21/28 , H01L21/3205
CPC分类号： B82Y10/00 , H01L21/76834 , H01L29/0665 , H01L51/0093 , H01L51/0504 , H01L51/102
摘要： Accordingly, the present invention provides a method of forming an electrode having reduced corrosion and water decomposition on a surface thereof. A substrate which has a conductive layer disposed thereon is provided and the conductive layer has an oxide layer with an exposed surface. The exposed surface of the oxide layer contacts a solution of an organic surface active compound in an organic solvent to form a protective layer of the organic surface active compound over the oxide layer. The protective layer has a thickness of from about 0.5 nm to about 5 nm and ranges therebetween depending on a chemical structure of the surface active compound.
摘要翻译：因此，本发明提供一种在其表面上形成具有降低的腐蚀和水分解的电极的方法。提供了具有设置在其上的导电层的衬底，并且导电层具有具有暴露表面的氧化物层。氧化物层的暴露表面接触有机表面活性化合物在有机溶剂中的溶液，以在氧化物层上形成有机表面活性化合物的保护层。根据表面活性化合物的化学结构，保护层的厚度为约0.5nm至约5nm，并且其范围。

34. 发明授权

US08131056B2 Constructing variability maps by correlating off-state leakage emission images to layout information 失效
标题翻译：通过将非状态泄漏图像与布局信息相关联来构建变异性图
公开(公告)号：US08131056B2
公开(公告)日：2012-03-06
申请号：US12241926
申请日：2008-09-30
申请人： Stanislav Polonsky , Peilin Song , Franco Stellari , Alan J. Weger
发明人： Stanislav Polonsky , Peilin Song , Franco Stellari , Alan J. Weger
IPC分类号： G06K9/00
CPC分类号： G06T7/001 , G06T2207/30148
摘要： Improved techniques are disclosed for monitoring or sensing process variations in integrated circuit designs. Such techniques provide such improvements by constructing variability maps correlating leakage emission images to layout information. By way of example, a method for monitoring one or more manufacturing process variations associated with a device under test (e.g., integrated circuit) comprises the following steps. An emission image representing an energy emission associated with a leakage current of the device under test is obtained. The emission image is correlated with a layout of the device under test to form a cross emission image. Common structures on the cross emission image are selected and identified as regions of interest. One or more variability measures (e.g., figures of merit) are calculated based on the energy emissions associated with the regions of interest. A variability map is created based on the calculated variability measures, wherein the variability map is useable to monitor the one or more manufacturing process variations associated with the device under test.
摘要翻译：公开了用于监测或感测集成电路设计中的工艺变化的改进的技术。这样的技术通过构建将泄漏发射图像与布局信息相关联的可变性图来提供这样的改进。作为示例，用于监测与被测器件（例如，集成电路）相关联的一个或多个制造工艺变化的方法包括以下步骤。获得表示与被测设备的泄漏电流相关联的能量发射的发射图像。发射图像与待测器件的布局相关，以形成交叉发射图像。选择交叉发射图像上的共同结构并将其识别为感兴趣的区域。基于与感兴趣区域相关联的能量排放来计算一个或多个可变性度量（例如，品质因素）。基于所计算的变异性度量创建变异性图，其中可变性图可用于监测与被测设备相关联的一个或多个制造过程变化。

35. 发明申请

US20110308969A1 REDUCING CORROSION AND WATER DECOMPOSITION ON A SURFACE OF A TITANIUM NITRIDE ELECTRODE 审中-公开
标题翻译：降低硝酸钛电极表面的腐蚀和水分解
公开(公告)号：US20110308969A1
公开(公告)日：2011-12-22
申请号：US12820574
申请日：2010-06-22
申请人： Ali Afzali-Azdakani , Shafaat Ahmed , Hariklia Deligianni , Stefan Harrer , Binquan Luan , Glenn J. Martyna , Hongbo Peng , Stanislav Polonsky , Stephen Rossnagel , Xiaoyan Shao , Gustavo A. Stolovitzky
发明人： Ali Afzali-Azdakani , Shafaat Ahmed , Hariklia Deligianni , Stefan Harrer , Binquan Luan , Glenn J. Martyna , Hongbo Peng , Stanislav Polonsky , Stephen Rossnagel , Xiaoyan Shao , Gustavo A. Stolovitzky
IPC分类号： G01N17/04
CPC分类号： G01N17/04
摘要： The present invention provides a method of reducing corrosion and water decomposition on a surface of an electrode having a titanium nitride conductive layer disposed on a substrate and estimating extent of reduction thereof. The electrode is immersed into a solution containing a hydroxyl-functional compound. Thereafter, a voltage is applied to the titanium nitride conductive layer of the electrode. The extent of oxidation of the titanium nitride conductive layer is correlated with the extent of formation of oxide of titanium nitride and/or the extent of oxidation of the titanium nitride conductive layer is correlated with the increase of surface roughness. The extent of water decomposition is correlated with formation of hydrogen and oxygen bubbles.
摘要翻译：本发明提供了在具有设置在基板上的具有氮化钛导电层的电极的表面上减少腐蚀和水分解的方法，并且估计其还原程度。将电极浸入含有羟基官能化合物的溶液中。然后，向电极的氮化钛导电层施加电压。氮化钛导电层的氧化程度与氮化钛的氧化物的形成程度和/或氮化钛导电层的氧化程度与表面粗糙度的增加有关。水分解的程度与氢气和氧气泡的形成有关。

36. 发明申请

US20100025249A1 Systems and Methods for Controlling the Position of a Charged Polymer Inside a Nanopore 审中-公开
标题翻译：控制纳米孔内电荷聚合物位置的系统和方法
公开(公告)号：US20100025249A1
公开(公告)日：2010-02-04
申请号：US12540553
申请日：2009-08-13
申请人： Stanislav Polonsky , Stephen M. Rossnagel , Gustavo A. Stolovitzky
发明人： Stanislav Polonsky , Stephen M. Rossnagel , Gustavo A. Stolovitzky
IPC分类号： B01D61/46
CPC分类号： G01N33/48721 , B82Y15/00 , B82Y30/00 , C12Q1/6825 , C12Q1/6869 , G01N2015/0038 , Y10S977/924 , C12Q2565/631 , C12Q2565/607 , C12Q2563/155
摘要： Techniques for controlling the position of a charged polymer inside a nanopore are provided. For example, one technique includes using electrostatic control to position a linear charged polymer inside a nanopore, and creating an electrostatic potential well inside the nanopore, wherein the electrostatic potential well controls a position of the linear charged polymer inside the nanopore.
摘要翻译：提供了用于控制纳米孔内带电聚合物位置的技术。例如，一种技术包括使用静电控制将线性带电聚合物定位在纳米孔内，并在纳米孔内产生静电势阱，其中静电势阱控制纳米孔内线性带电聚合物的位置。

37. 发明授权

US07446550B2 Enhanced signal observability for circuit analysis 有权
标题翻译：电路分析增强的信号可观测性
公开(公告)号：US07446550B2
公开(公告)日：2008-11-04
申请号：US11949325
申请日：2007-12-03
申请人： Chandler Todd McDowell , Stanislav Polonsky , Peilin Song , Franco Stellari , Alan J. Weger
发明人： Chandler Todd McDowell , Stanislav Polonsky , Peilin Song , Franco Stellari , Alan J. Weger
IPC分类号： G01R31/02
CPC分类号： G01R31/311
摘要： Methods and arrangements to enhance photon emissions responsive to a signal within an integrated circuit (IC) for observability of signal states utilizing, e.g., picosecond imaging circuit analysis (PICA), are disclosed. Embodiments attach a beacon to the signal of interest and apply a voltage across the beacon to enhance photon emissions responsive to the signal of interest. The voltage is greater than the operable circuit voltage, Vdd, to enhance photon emissions with respect to intensity and energy. Thus, the photon emissions are more distinguishable from noise. In many embodiments, the beacon includes a transistor and, in several embodiments, the beacon includes an enablement device to enable and disable photon emissions from the beacon. Further, a PICA detector may capture photon emissions from the beacon and process the photons to generate time traces.
摘要翻译：公开了利用例如皮秒成像电路分析（PICA）来增强响应于集成电路（IC）内的信号的信号状态的可观察性的光子发射的方法和装置。实施例将信标连接到感兴趣的信号，并在信标之间施加电压以增强响应于感兴趣的信号的光子发射。电压大于可操作电路电压Vdd，以增强相对于强度和能量的光子发射。因此，光子发射与噪声更为区别。在许多实施例中，信标包括晶体管，并且在几个实施例中，信标包括启用和禁用来自信标的光子发射的启用装置。此外，PICA检测器可以捕获来自信标的光子发射并处理光子以产生时间迹线。

38. 发明申请

US20080187915A1 Systems and Methods for Controlling the Position of a Charged Polymer Inside a Nanopore 有权
标题翻译：控制纳米孔内电荷聚合物位置的系统和方法
公开(公告)号：US20080187915A1
公开(公告)日：2008-08-07
申请号：US11670621
申请日：2007-02-02
申请人： Stanislav Polonsky , Stephen M. Rossnagel , Gustavo A. Stolovitzky
发明人： Stanislav Polonsky , Stephen M. Rossnagel , Gustavo A. Stolovitzky
IPC分类号： C12Q1/68 , G01N27/30
CPC分类号： G01N33/48721 , B82Y15/00 , B82Y30/00 , C12Q1/6825 , C12Q1/6869 , G01N2015/0038 , Y10S977/924 , C12Q2565/631 , C12Q2565/607 , C12Q2563/155
摘要： Techniques for controlling the position of a charged polymer inside a nanopore are provided. For example, one technique includes using electrostatic control to position a linear charged polymer inside a nanopore, and creating an electrostatic potential well inside the nanopore, wherein the electrostatic potential well controls a position of the linear charged polymer inside the nanopore.
摘要翻译：提供了用于控制纳米孔内带电聚合物位置的技术。例如，一种技术包括使用静电控制将线性带电聚合物定位在纳米孔内，并在纳米孔内产生静电势阱，其中静电势阱控制纳米孔内线性带电聚合物的位置。

39. 发明授权

US07114136B2 Method for VLSI system debug and timing analysis 有权
标题翻译： VLSI系统调试和时序分析方法
公开(公告)号：US07114136B2
公开(公告)日：2006-09-26
申请号：US10663020
申请日：2003-09-16
申请人： Harold W. Chase , Daniel R. Knebel , Dennis G. Menzer , Stanislav Polonsky , Pia N. Sanda
发明人： Harold W. Chase , Daniel R. Knebel , Dennis G. Menzer , Stanislav Polonsky , Pia N. Sanda
IPC分类号： G06F17/50
CPC分类号： G06F17/5031
摘要： A method for characterizing circuit activity in an IC. Generally, the method comprises the steps of activating an IC, resolving the switching activity in space and time, and generating a representation of the switching behavior which differentiates the time that circuits or transistors switch. One embodiment of the invention, utilizes a method such as, but not limited to, time resolved photon emission to observe transistor level switching activity in an integrated circuit (IC).
摘要翻译：一种用于表征IC中的电路活动的方法。通常，该方法包括以下步骤：激活IC，解决空间和时间的切换活动，以及生成区分电路或晶体管切换时间的开关行为的表示。本发明的一个实施例利用诸如但不限于时间分辨光子发射的方法来观察集成电路（IC）中的晶体管级切换活动。

40. 发明申请

US20060028219A1 Enhanced signal observability for circuit analysis 有权
标题翻译：电路分析增强的信号可观测性
公开(公告)号：US20060028219A1
公开(公告)日：2006-02-09
申请号：US10912493
申请日：2004-08-05
申请人： Chandler McDowell , Stanislav Polonsky , Peilin Song , Franco Stellari , Alan Weger
发明人： Chandler McDowell , Stanislav Polonsky , Peilin Song , Franco Stellari , Alan Weger
IPC分类号： G01R31/28 , G06K9/00
CPC分类号： G01R31/311
摘要： Methods and arrangements to enhance photon emissions responsive to a signal within an integrated circuit (IC) for observability of signal states utilizing, e.g., picosecond imaging circuit analysis (PICA), are disclosed. Embodiments attach a beacon to the signal of interest and apply a voltage across the beacon to enhance photon emissions responsive to the signal of interest. The voltage is greater than the operable circuit voltage, Vdd, to enhance photon emissions with respect to intensity and energy. Thus, the photon emissions are more distinguishable from noise. In many embodiments, the beacon includes a transistor and, in several embodiments, the beacon includes an enablement device to enable and disable photon emissions from the beacon. Further, a PICA detector may capture photon emissions from the beacon and process the photons to generate time traces.
摘要翻译：公开了利用例如皮秒成像电路分析（PICA）来增强响应于集成电路（IC）内的信号的信号状态的可观察性的光子发射的方法和装置。实施例将信标连接到感兴趣的信号，并在信标之间施加电压以增强响应于感兴趣的信号的光子发射。电压大于可操作电路电压Vdd，以增强相对于强度和能量的光子发射。因此，光子发射与噪声更为区别。在许多实施例中，信标包括晶体管，并且在几个实施例中，信标包括启用和禁用来自信标的光子发射的启用装置。此外，PICA检测器可以捕获来自信标的光子发射并处理光子以产生时间迹线。

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