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31. 发明授权

US08274286B2 System and method for multi-spectral MR imaging near metal 有权
标题翻译：用于金属附近的多光谱MR成像的系统和方法
公开(公告)号：US08274286B2
公开(公告)日：2012-09-25
申请号：US12860272
申请日：2010-08-20
申请人： Kevin M. Koch , Kevin F. King , Graeme C. McKinnon , Brian Hargreaves
发明人： Kevin M. Koch , Kevin F. King , Graeme C. McKinnon , Brian Hargreaves
IPC分类号： G01V3/00
CPC分类号： G01R33/56563 , G01R33/243 , G01R33/4822 , G01R33/5608
摘要： A system and method for multi-spectral MR imaging near metal include a computer programmed to calculate an MR pulse sequence comprising a plurality of RF pulses configured to excite spins in an imaging object and comprising a plurality of volume selection gradients and determine a plurality of distinct offset frequency values. For each respective determined offset frequency value, the computer is programmed to execute the MR pulse sequence having a central transmit frequency and a central receive frequency of the MR pulse sequence set to the respective determined offset frequency value. The computer is also programmed to acquire a three-dimensional (3D) MR data set for each MR pulse sequence execution and generate a composite image based on data from each of the acquired 3D MR data sets.
摘要翻译：用于金属附近的多光谱MR成像的系统和方法包括被编程为计算MR脉冲序列的计算机，该计算机包括被配置为激励成像对象中的自旋的多个RF脉冲，并且包括多个体积选择梯度并且确定多个不同的偏移频率值。对于每个相应确定的偏移频率值，计算机被编程为执行MR脉冲序列，该MR脉冲序列具有被设置为相应确定的偏移频率值的MR脉冲序列的中心发射频率和中心接收频率。计算机还被编程为获取每个MR脉冲序列执行的三维（3D）MR数据集，并且基于来自每个获取的3D MR数据集的数据生成合成图像。

32. 发明授权

US07592808B1 System and method for reducing MR scan time using partial fourier acquisition and compressed sensing 有权
标题翻译：使用部分傅里叶采集和压缩感测减少MR扫描时间的系统和方法
公开(公告)号：US07592808B1
公开(公告)日：2009-09-22
申请号：US12115786
申请日：2008-05-06
申请人： Kevin F. King
发明人： Kevin F. King
IPC分类号： G01V3/00
CPC分类号： G01R33/56545 , G01R33/561
摘要： A system and method for reducing the scan time of an MR imaging system using a data acquisition technique that combines partial Fourier acquisition and compressed sensing includes a computer programmed to acquire a partial MR data set in k-space along a phase encoding direction, the data set having missing data in the phase encoding direction due to the omission of phase encoding steps. The computer is further programmed to generate an estimate of a reconstructed image, compensate the partial MR data set for the missing data, and reconstruct an MR image by iteratively minimizing the total squared difference between the k-space data of the estimate of the reconstructed image and the measured k-space data of the compensated partial MR data set.
摘要翻译：使用组合部分傅立叶获取和压缩感测的数据采集技术来减少MR成像系统的扫描时间的系统和方法包括被编程为沿着相位编码方向在k空间中获取部分MR数据集的计算机，数据由于缺少相位编码步骤，在相位编码方向上设置有丢失的数据。计算机还被编程为生成重建图像的估计，补偿缺失数据的部分MR数据集，并且通过迭代地最小化重构图像的估计的k空间数据之间的总平方差来重构MR图像以及经补偿的部分MR数据集的测量的k空间数据。

33. 发明申请

US20090184711A1 SYSTEM AND METHOD FOR MR IMAGING IN INHOMOGENEOUS MAGNETIC FIELDS 有权
标题翻译：非均匀磁场中MR成像的系统和方法
公开(公告)号：US20090184711A1
公开(公告)日：2009-07-23
申请号：US12016331
申请日：2008-01-18
申请人： Kevin M, Koch , Kevin F. King , Reed F. Busse
发明人： Kevin M, Koch , Kevin F. King , Reed F. Busse
IPC分类号： G01R33/54
CPC分类号： G01R33/243 , G01R33/4822 , G01R33/5608 , G01R33/56563
摘要： An apparatus and method for MR imaging in inhomogeneous magnetic fields includes acquisition of a plurality of three-dimensional (3D) MR data sets, each data set having a central transmit frequency and a central receive frequency set to a frequency offset that is distinct for each 3D MR data set. A composite image is generated based on the plurality of 3D MR data sets.
摘要翻译：用于不均匀磁场中的MR成像的装置和方法包括获取多个三维（MR）MR数据集，每个数据集具有中心发射频率和中心接收频率，该频率偏移设定为每个 3D MR数据集。基于多个3D MR数据集生成合成图像。

34. 发明授权

US07466131B1 System and method for designing multi-channel RF pulses for MR imaging 有权
标题翻译：用于MR成像设计多通道RF脉冲的系统和方法
公开(公告)号：US07466131B1
公开(公告)日：2008-12-16
申请号：US11738225
申请日：2007-04-20
申请人： Dan Xu , Kevin F. King , Zhi-Pei Liang
发明人： Dan Xu , Kevin F. King , Zhi-Pei Liang
IPC分类号： G01V3/00
CPC分类号： G01R33/4836 , G01R33/4824 , G01R33/4833
摘要： A system and method are provided for designing RF pulses for multi-channel and/or multi-dimensional spatially-selective applications using a linear approximation. Embodiments of the system and method may use a generalized linear-class large tip angle approximation to design RF pulses for multi-channel and parallel transmission. Further, some of these approximations allow for the design of arbitrarily large flip angles, irregularly-shaped flip angle profiles, or arbitrary initial magnetization values. Embodiments of the system and method may also provide for the design of k-space trajectories which aid in maintaining assumptions of the various linear class approximations.
摘要翻译：提供了一种系统和方法，用于使用线性近似来设计用于多通道和/或多维空间选择性应用的RF脉冲。该系统和方法的实施例可以使用广义线性级大尖角近似来设计用于多通道和并行传输的RF脉冲。此外，这些近似中的一些允许设计任意大的翻转角，不规则形状的翻转轮廓或任意的初始磁化值。系统和方法的实施例还可以提供有助于维持各种线性类近似的假设的k空间轨迹的设计。

35. 发明申请

US20080238425A1 SYSTEM AND METHOD FOR DESIGNING IMPROVED RF PULSE PROFILES 有权
标题翻译：用于设计改进的RF脉冲轮廓的系统和方法
公开(公告)号：US20080238425A1
公开(公告)日：2008-10-02
申请号：US11694617
申请日：2007-03-30
申请人： Dan Xu , Kevin F. King , Zhi-Pei Liang
发明人： Dan Xu , Kevin F. King , Zhi-Pei Liang
IPC分类号： G01R33/32
CPC分类号： G01R33/4833
摘要： A system and method are provided for designing RF pulses which have improved magnetization profiles. By utilizing an optimal control approach as an alternative to, or in combination with, non-iterative approximations, RF pulses generated by the system and method described herein will exhibit less deviation from that of “ideal” Bloch solutions. Consequently, the magnetization profiles produced by the RF pulses generated by the system and method described herein will be closer to the desired profiles. In addition, limitations of non-iterative approximations, such as maximum tip angle limits and linearity constraints, can be avoided.
摘要翻译：提供了一种用于设计具有改进的磁化分布的RF脉冲的系统和方法。通过利用最优控制方法作为非迭代近似的替代方案或与非迭代近似组合，由本文描述的系统和方法产生的RF脉冲将表现出与“理想”Bloch解决方案的偏差较小的偏差。因此，由本文所述的系统和方法产生的RF脉冲产生的磁化曲线将更接近所需的轮廓。此外，可以避免非迭代近似的限制，例如最大尖角限制和线性约束。

36. 发明授权

US07250762B2 Method and system of MR imaging with reduced FSE cusp artifacts 有权
标题翻译：降低FSE尖点假象的MR成像方法和系统
公开(公告)号：US07250762B2
公开(公告)日：2007-07-31
申请号：US11176921
申请日：2005-07-07
申请人： Kevin F. King , Richard S. Hinks
发明人： Kevin F. King , Richard S. Hinks
IPC分类号： G01V3/00
CPC分类号： G01R33/56518 , G01R33/5611 , G01R33/5615 , G01R33/5617
摘要： Coil sensitivity of a receive coil to a gradient null location is measured and, from the measurements, a coil calibration value is determined and used to modify the MR data acquired with that receive coil to reduce the adverse effects of gradient nulling on MR images. Coil sensitivity values are determined for each coil of a coil array and the data for each coil is respectively weighted. An image that is substantially free of gradient null artifacts or ghosting is then reconstructed from the weighted data.
摘要翻译：测量接收线圈到梯度零点位置的线圈灵敏度，并且从测量中确定线圈校准值并用于修改用该接收线圈获取的MR数据，以减少梯度零点对MR图像的不利影响。对于线圈阵列的每个线圈确定线圈灵敏度值，并且分别对每个线圈的数据进行加权。然后从加权数据重建基本上不含梯度零伪影或重影的图像。

37. 发明授权

US07197353B2 Sensitivity encoding MRI acquisition method 失效
标题翻译：灵敏度编码MRI采集方法
公开(公告)号：US07197353B2
公开(公告)日：2007-03-27
申请号：US09952446
申请日：2001-09-14
申请人： Kevin F. King , Lisa C. Angelos
发明人： Kevin F. King , Lisa C. Angelos
IPC分类号： A61B5/05
CPC分类号： G01R33/5611 , G01R33/3415 , G01R33/58
摘要： A sensitivity encoding method (SENSE) is used to acquire an MR image having a reduced field of view. The number of aliased replicates caused by surrounding object boundaries is calculated for each image pixel location to obtain optimal aliasing artifact suppression without reducing image SNR.
摘要翻译：使用灵敏度编码方法（SENSE）来获取具有减小的视场的MR图像。针对每个图像像素位置计算由周围物体边界引起的混叠重复数，以获得最佳的混叠伪影抑制，而不降低图像SNR。

38. 发明授权

US06836116B2 Sensitivity encoding magnetic resonance imaging method and system 有权
标题翻译：灵敏度编码磁共振成像方法和系统
公开(公告)号：US06836116B2
公开(公告)日：2004-12-28
申请号：US10064309
申请日：2002-07-01
申请人： Kevin F. King , Elisabeth Angelos
发明人： Kevin F. King , Elisabeth Angelos
IPC分类号： G01V300
CPC分类号： G01R33/583 , G01R33/5611
摘要： A method and apparatus are disclosed for deriving an enhanced sensitivity matrix for describing coil sensitivity in a magnetic resonance imaging system. The enhanced sensitivity matrix provides sensitivity information for pixels near the edge of the imaged object such that pixels near the edge for which there was no sensitivity information are associated with a derived sensitivity. Likewise pixels near the edge for which there is measured sensitivity information are instead associated with a derived sensitivity to offset deficient sensitivity measurements near the edge of the object.
摘要翻译：公开了一种用于导出用于描述磁共振成像系统中的线圈灵敏度的增强灵敏度矩阵的方法和装置。增强的灵敏度矩阵为成像对象的边缘附近的像素提供灵敏度信息，使得不存在敏感度信息的边缘附近的像素与衍生的灵敏度相关联。类似地，具有测量的灵敏度信息的边缘附近的像素与衍生的灵敏度相关联，以抵消物体边缘附近的不足的灵敏度偏移。

39. 发明授权

US06559642B2 Calibration method for use with sensitivity encoding MRI acquisition 有权
公开(公告)号：US06559642B2
公开(公告)日：2003-05-06
申请号：US09851775
申请日：2001-05-09
申请人： Kevin F. King
发明人： Kevin F. King
IPC分类号： G01V300
CPC分类号： G01R33/3415 , G01R33/5611
摘要： Calibration data is acquired during a prescan in an MRI system from each local coil in a coil array. The calibration data is used to calculate a sensitivity matrix S which is employed in a SENSE technique to reconstruct an MR image acquired with the same local coils.

40. 发明授权

US06288545B1 Method and apparatus for calibration of RF and gradient field time delays 有权
标题翻译：用于校准RF和梯度场时间延迟的方法和装置
公开(公告)号：US06288545B1
公开(公告)日：2001-09-11
申请号：US09274468
申请日：1999-03-22
申请人： Kevin F. King , Alexander Ganin
发明人： Kevin F. King , Alexander Ganin
IPC分类号： G01V300
CPC分类号： G01R33/58
摘要： A technique is disclosed for calibrating time delays between RF and gradient frequency pulses in a magnetic resonance imaging system. The calibration procedure includes the formation of calibration images of a phantom positioned in the gradient field system. Calibration images are processed and compared to one another to determine deviation between locations in the gradient field system and the impact of radio frequency-to-gradient waveform time delays on the deviations. Optimal time delays are identified which minimize the deviations between the calibration images. Multiple axes of the system may be calibrated through the use of symmetrical phantoms and similar pulse sequences of each axis. A spectral-spatial pulse sequence is employed bearing the calibration routine.
摘要翻译：公开了一种用于校准磁共振成像系统中RF和梯度频率脉冲之间的时间延迟的技术。校准过程包括形成位于梯度场系统中的体模的校准图像。校准图像被处理并相互比较以确定梯度场系统中的位置之间的偏差以及射频到梯度波形时间延迟对偏差的影响。识别最佳时间延迟，其最小化校准图像之间的偏差。可以通过使用每个轴的对称体模和类似的脉冲序列校准系统的多个轴。采用校准程序的谱空间脉冲序列。

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