专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

US6096732A Steroid esters, process for their production and their pharmaceutical use 失效
标题翻译：类固醇酯，其生产过程及其药物用途
公开(公告)号：US6096732A
公开(公告)日：2000-08-01
申请号：US986592
申请日：1997-12-08
申请人： Ulrich Klar , Arwed Cleve , Wolfgang Schwede , Gunter Neef , Eckhard Ottow , Kristof Chwalisz , Martin Schneider
发明人： Ulrich Klar , Arwed Cleve , Wolfgang Schwede , Gunter Neef , Eckhard Ottow , Kristof Chwalisz , Martin Schneider
IPC分类号： A61K31/565 , A61P35/00 , C07J53/00 , A61K31/56
CPC分类号： C07J53/002 , Y10S514/843
摘要： Steroid esters of formula I ##STR1## are described, wherein m, n and x are as defined by the specification. The compounds are distinguished from the basic hydroxy compounds by considerably improved solubility as well by increased biological activity and selectivity.The compounds are suitable for the production of pharmaceutical agents.
摘要翻译：描述式I的类固醇酯，其中m，n和x如本说明书所定义。通过显着改善溶解度以及增加的生物活性和选择性，化合物与碱性羟基化合物的区别。该化合物适用于生产药剂。

32. 发明授权

US5807899A Triphenylethylenes, process for their production, pharmaceutical preparations that contain these triphenylethylenes as well as their use for the production of pharmaceutical agents 失效
标题翻译：三苯乙烯，其制备方法，含有这些三苯乙烯的药物制剂以及其用于生产药剂的用途
公开(公告)号：US5807899A
公开(公告)日：1998-09-15
申请号：US675906
申请日：1996-07-05
申请人： Rolf Bohlmann , Joseph Heindl , Hermann Kunzer , Yukishige Nishino , Karsten Parczyk , Martin Schneider
发明人： Rolf Bohlmann , Joseph Heindl , Hermann Kunzer , Yukishige Nishino , Karsten Parczyk , Martin Schneider
IPC分类号： C07C317/18 , C07C317/28 , C07C323/12 , C07C323/25 , C07C323/60 , C07D213/32 , C07D213/34 , A61K31/10 , C07C317/12 , C07C321/18 , C07C321/20
CPC分类号： C07C323/25 , C07C317/18 , C07C317/28 , C07C323/12 , C07C323/60 , C07D213/32 , C07D213/34
摘要： This invention describes the new triphenylethylenes of general formula I ##STR1## in which n means an integer from 1 to 10, R' means a sulfur-containing organic radical, R" means a hydrogen atom, an iodine atom or a hydroxy groups, E means a hydrogen atom, G means a hydrogen atom or E and G together mean a methylene bridge. The new compounds have strong antiestrogenic properties and are suitable for the production of pharmaceutical agents, for example for treating breast cancer.
摘要翻译：本发明描述了通式I（I）的新的三苯乙烯，其中n表示1至10的整数，R'表示含硫有机基团，R“表示氢原子，碘原子或羟基，E表示氢原子，G表示氢原子或E和G一起表示亚甲基桥。新化合物具有强的抗雌激素特性，适用于制药，例如用于治疗乳腺癌。

33. 发明授权

US5639839A Oligomers and polymers of aminoalkenes 失效
标题翻译：氨基烯烃的低聚物和聚合物
公开(公告)号：US5639839A
公开(公告)日：1997-06-17
申请号：US529971
申请日：1995-09-19
申请人： David Fischer , Franz Langhauser , Jurgen Kerth , Gunther Schweier , Rolf Muelhaupt , Martin Schneider
发明人： David Fischer , Franz Langhauser , Jurgen Kerth , Gunther Schweier , Rolf Muelhaupt , Martin Schneider
IPC分类号： C07F7/12 , C08F4/642 , C08F4/68 , C08F8/00 , C08F30/08 , C08F210/00 , C08F230/08
CPC分类号： C08F30/08 , C08F210/00 , Y10S526/943
摘要： Oligomers and polymers, obtainable fromA) from 0.001 to 100 mol % of at least one aminoalkene of the general formula I ##STR1## where X is an integer from 0 to 25 andR.sup.1 to R.sup.6 are hydrogen, C.sub.1 - to C.sub.10 -alkyl, 5- to 7-membered cycloalkyl which, in turn, can carry C.sub.1 - to C.sub.6 -alkyl groups as substituents or C.sub.6 - to C.sub.15 -aryl andB) from 0 to 99.999 mol % of at least one alkene,for x=1 in formula I propene being excluded as component B).
摘要翻译：低聚物和聚合物，可由A）0.001至100摩尔％的至少一种通式I的氨基链烯，其中X为0至25的整数，R 1至R 6为氢，C 1至C 10 - 烷基 5至7元环烷基，其又可以携带C 1至C 6烷基作为取代基或C 6至C 15 - 芳基，B）为0至99.999摩尔％的至少一种烯烃，x = 1 在式I中，作为组分B）排除丙烯。

34. 发明授权

US5280035A Cycloalkylene azoles and their use as aromatase inhibitors 失效
标题翻译：环亚烷基唑类及其作为芳香酶抑制剂的用途
公开(公告)号：US5280035A
公开(公告)日：1994-01-18
申请号：US889331
申请日：1992-05-28
申请人： Rolf Bohlmann , Peter Strehlke , David Henderson , Martin Schneider , Yukishige Nishino
发明人： Rolf Bohlmann , Peter Strehlke , David Henderson , Martin Schneider , Yukishige Nishino
IPC分类号： A61K31/415 , A61K31/41 , A61K31/4174 , A61K31/4178 , A61K31/4192 , A61K31/4196 , A61P5/32 , A61P13/00 , A61P13/02 , A61P15/00 , A61P35/00 , C07D233/56 , C07D233/58 , C07D233/64 , C07D249/04 , C07D249/08 , C07D401/08 , C07D405/08 , C07D409/06 , C07D409/08 , C07D521/00 , C07D407/06
CPC分类号： C07D231/12 , C07D233/56 , C07D249/04 , C07D249/08
摘要： The disclosure relates to cycloalkylene azoles of general Formula I ##STR1## wherein ##STR2## is a carbocyclic or carbopolycyclic group optionally carrying at least one alkyl substituent,is the grouping ##STR3## an oxygen or sulfur atom, and Y and Z, independently of each other, are ##STR4## or a nitrogen atom, as well as their pharmaceutically compatible addition salts with acids as well as processes for production thereof. The compounds possess strongly aromatase-inhibiting activity and are suitable for the preparation of medicinal agents.Methods for treating estrogen induced or stimulated tumors, male infertility, and impending cardiac infarction with these compounds are also provided as well as methods for inhbiiting female fertility.
摘要翻译：本公开涉及通式I的环亚烷基唑类（I）其中，IMAGE是任选携带至少一个烷基取代基的碳环或多碳环，是氧或硫原子，Y和Z 彼此独立地是氮或氮原子，以及它们与酸的药学上相容的加成盐以及其制备方法。该化合物具有强烈的芳香酶抑制活性，适用于制备药剂。还提供了用于治疗雌激素诱导或刺激的肿瘤，男性不育症和即将发生的这些化合物的心肌梗死的方法以及用于吸收女性生殖力的方法。

35. 发明授权

US10011664B2 Functionalized nitrile rubbers and the production thereof 有权
公开(公告)号：US10011664B2
公开(公告)日：2018-07-03
申请号：US13982520
申请日：2012-01-25
申请人： Werner Obrecht , Julia Maria Jeschko , Oskar Nuyken , Martin Schneider
发明人： Werner Obrecht , Julia Maria Jeschko , Oskar Nuyken , Martin Schneider
IPC分类号： C08C19/28 , B29C45/00 , B01J31/22 , B01J31/18 , C08C19/00 , B01J31/24 , B29K55/00
CPC分类号： C08C19/28 , B01J31/1805 , B01J31/181 , B01J31/183 , B01J31/2208 , B01J31/2226 , B01J31/2265 , B01J31/2273 , B01J31/2278 , B01J31/2291 , B01J31/2404 , B01J2231/543 , B01J2231/546 , B01J2531/64 , B01J2531/821 , B01J2531/825 , B01J2540/62 , B29C45/0001 , B29K2055/00 , C08C19/00 , C08C19/08 , C08C2019/09 , C08L15/00
摘要： Provided are new functionalized nitrile rubbers, which may optionally also be in partially or wholly hydrogenated form, and also a process for preparing them by metathesis of nitrile rubbers in the presence of a metathesis catalyst and at least one functionalized allyl compound. The new functionalized nitrile rubbers are suitable for producing vulcanizable mixtures and allow the production of vulcanizates having very stable networks. Also made possible, in particular, is the synthesis of block copolymers.

36. 发明申请

US20160092820A1 METHOD AND SYSTEM FOR PROVIDING DATA ANALYTICS RESULTS 审中-公开
标题翻译：提供数据分析结果的方法和系统
公开(公告)号：US20160092820A1
公开(公告)日：2016-03-31
申请号：US14864415
申请日：2015-09-24
申请人： Alexander Ebel , Martin Schneider , Sonja Zillner
发明人： Alexander Ebel , Martin Schneider , Sonja Zillner
IPC分类号： G06Q10/06
CPC分类号： G06Q10/06395 , G05B17/02 , G05B19/41885 , Y02P90/26
摘要： A system for providing data analytics results for a process performed in an industrial plant includes a knowledge model repository configured to store semantic knowledge models. The system also includes selection unit configured to select at least one analytics application describing semantically at least one process step and at least one parameter required for accomplishing an analytics task. The system includes a processing unit configured to process the selected analytics application and selected instantiated semantic knowledge models to infer at least one storage location of at least one data source of the industrial plant, and an execution engine configured to execute the selected data analytics application using accessed process data provided by the inferred data sources of the industrial plant to generate the data analytics results.
摘要翻译：用于为在工厂中执行的处理提供数据分析结果的系统包括被配置为存储语义知识模型的知识模型存储库。该系统还包括选择单元，其被配置为选择描述语义上至少一个处理步骤的至少一个分析应用程序和完成分析任务所需的至少一个参数。该系统包括处理单元，该处理单元被配置为处理所选择的分析应用程序和所选择的实例化语义知识模型以推断出工业工厂的至少一个数据源的至少一个存储位置，以及执行引擎，被配置为使用由工业工厂的推断数据源提供的访问过程数据，以生成数据分析结果。

37. 发明授权

US09123999B2 Imaging system 有权
标题翻译：成像系统
公开(公告)号：US09123999B2
公开(公告)日：2015-09-01
申请号：US13521932
申请日：2011-01-14
申请人： Martin Schneider , Michael Crowley , Brendan Lyons , David O'Driscoll , Klaus-Michael Hussmann
发明人： Martin Schneider , Michael Crowley , Brendan Lyons , David O'Driscoll , Klaus-Michael Hussmann
IPC分类号： H01Q3/46 , G01S13/89 , H01Q3/24 , G01V8/00
CPC分类号： H01Q3/46 , G01S13/89 , G01V8/005 , H01Q3/247
摘要： The invention relates to an imaging system having a reflect array for reflection of radiation such as millimeter-wave radiation. It can apply to imaging systems which operate over a wide range of wavelengths.
摘要翻译：本发明涉及具有用于反射诸如毫米波辐射的辐射的反射阵列的成像系统。它可以应用于在宽波长范围内工作的成像系统。

38. 发明授权

US09051400B2 Catalyst components for the polymerization of olefins and catalysts therefrom obtained 有权
标题翻译：用于烯烃聚合的催化剂组分及其催化剂
公开(公告)号：US09051400B2
公开(公告)日：2015-06-09
申请号：US13516709
申请日：2010-12-17
申请人： Friedhelm Gundert , Martin Schneider
发明人： Friedhelm Gundert , Martin Schneider
IPC分类号： C08F4/646 , C08F110/02 , C08F10/00
CPC分类号： C08F10/00 , C08F110/02 , C08F4/6565 , C08F4/6567 , C08F2500/12 , C08F2500/18 , C08F2500/24
摘要： A catalyst component for the polymerization of olefins comprising Mg, Ti and Cl obtained by a process comprising the following steps: a) reacting a precursor of formula MgCl2.mEtOH, wherein m is equal to, or lower than, 1.5 having a porosity due to pores with radius up to 1μ of higher than 0.4 cm3/g with an alcohol of formula RIOH where RI is an alkyl different from ethyl, a cycloalkyl or aryl radical having 3-20 carbon atoms said RIOH being reacted with the said precursor using molar ratio RIOH/Mg ranging from 0.01 to 10; b) reacting the product obtained in (a) with TiCl4 using Ti/Mg molar ratio ranging from 0.01 to 15, c) reacting the product obtained in (b) with a silicon compound of formula RIaRIIbSi(ORIII)4−(a+b) where RI-RIII are linear or branched, cycloalkyl, aryl C1-C20 hydrocarbon groups a and b are integers from 0 to 2.
摘要翻译：用于通过包括以下步骤的方法获得的包含Mg，Ti和Cl的烯烃聚合的催化剂组分：a）使式MgCl 2·mEtOH的前体与其反应，其中m等于或低于1.5，由于其中R1是不同于乙基的烷基，具有3-20个碳原子的环烷基或芳基，所述RIOH与所述前体反应，使用摩尔比，其中半数高达1μs，高于0.4cm 3 / g的孔 RIOH / Mg为0.01〜10; b）将（a）中获得的产物与TiCl 4的摩尔比为0.01至15，c）使（b）中获得的产物与式RIaRIIbSi（ORIII）4-（a + b）的硅化合物反应，）其中RI-RIII是直链或支链的，环烷基，芳基C1-C20烃基a和b是0-2的整数。

39. 发明授权

US09029323B2 Neurturin conjugates for pharmaceutical use 有权
标题翻译：用于药物用途的Neurturin共轭物
公开(公告)号：US09029323B2
公开(公告)日：2015-05-12
申请号：US12774235
申请日：2010-05-05
申请人： Matthias Austen , Marcus Geese , Rainer Mussmann , Friedrich Harder , Thomas Siegmund , Martin Schneider
发明人： Matthias Austen , Marcus Geese , Rainer Mussmann , Friedrich Harder , Thomas Siegmund , Martin Schneider
IPC分类号： A61K38/18 , C07K14/475 , A61K47/48
CPC分类号： C07K14/4756 , A61K9/0019 , A61K38/185 , A61K47/60
摘要： The present invention relates to neurturin protein products conjugated to polyols and to pharmaceutical compositions comprising neurturin conjugates as active ingredients, preferably PEGylated neurturin conjugates or variants thereof, having increased bioavailability.
摘要翻译：本发明涉及与多元醇缀合的neururin蛋白产物和包含neurturin偶联物作为活性成分的药物组合物，优选聚乙二醇化的neururin缀合物或其变体，具有增加的生物利用度。

40. 发明授权

US08853193B2 Thienopyrimidines containing a substituted alkyl group for pharmaceutical compositions 有权
标题翻译：含有用于药物组合物的取代烷基的噻吩并嘧啶
公开(公告)号：US08853193B2
公开(公告)日：2014-10-07
申请号：US13035023
申请日：2011-02-25
申请人： Armin Heckel , Frank Himmelsbach , Joerg Kley , Thorsten Lehmann-Lintz , Norbert Redemann , Achim Sauer , Leo Thomas , Dieter Wiedenmayer , Phillip Black , Wesley Blackaby , Ian Linney , Matthias Austen , John Danilewicz , Martin Schneider , Kay Schreiter
发明人： Armin Heckel , Frank Himmelsbach , Joerg Kley , Thorsten Lehmann-Lintz , Norbert Redemann , Achim Sauer , Leo Thomas , Dieter Wiedenmayer , Phillip Black , Wesley Blackaby , Ian Linney , Matthias Austen , John Danilewicz , Martin Schneider , Kay Schreiter
IPC分类号： C07D495/04 , A61K31/519 , A61K31/5377 , A61K31/56 , A61P29/00 , A61P35/00 , A61P25/28 , A61P13/12 , A61K31/395
CPC分类号： C07D495/04
摘要： The present invention relates to novel thienopyrimidine compounds of general formula pharmaceutical compositions comprising these compounds and their therapeutic use for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof.
摘要翻译：本发明涉及包含这些化合物的通式药物组合物的新型噻吩并嘧啶化合物及其用于预防和/或治疗可受到抑制Mnk1和/或Mnk2（Mnk2a或Mnk2b的激酶活性）的疾病的治疗用途）和/或其变体。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式