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31. 发明授权

US06916861B2 Pigment containing ink and production method thereof 失效
标题翻译：含油墨的颜料及其制备方法
公开(公告)号：US06916861B2
公开(公告)日：2005-07-12
申请号：US10133402
申请日：2002-04-29
申请人： Tsuyoshi Nomoto , Tetsuya Yano , Shinya Kozaki , Tsutomu Honma
发明人： Tsuyoshi Nomoto , Tetsuya Yano , Shinya Kozaki , Tsutomu Honma
IPC分类号： C12N15/09 , C08G63/688 , C09C3/10 , C09D11/00 , C12N9/24 , C12P7/62 , C12P11/00 , C12R1/01 , C12R1/38 , C12N7/62 , C03G9/00 , C03G17/00
CPC分类号： C09D11/322 , C08G63/6882 , C12P7/625 , C12P11/00 , Y10T428/254 , Y10T428/2991
摘要： A micro-capsulated pigment containing pigment ink being excellent in density, fineness, transparency, and coloring and color rendering properties required for ink solutions and having excellent dispersibility and dispersion stability with time due to the reduced particle size is provided. At least a color material with at least part of the surfaces of pigment particles covered with polyhydroxyalkanoate, and a medium for dispersion of the color material are used to obtain the pigment ink.
摘要翻译：提供了含有油墨溶液所需的密度，细度，透明度，着色和着色性优异的微胶囊颜料，并且由于粒径减小而具有优异的分散性和分散稳定性随着时间的推移。至少一种颜色材料，其颜料颗粒的至少一部分表面被聚羟基链烷酸酯覆盖，并且使用着色材料的分散介质来获得颜料墨。

32. 发明授权

US07056708B2 Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule 失效
标题翻译：从其分子中含有芳环的残基的烷烃生产聚羟基链烷酸酯的方法
公开(公告)号：US07056708B2
公开(公告)日：2006-06-06
申请号：US10410349
申请日：2003-04-10
申请人： Takashi Kenmoku , Etsuko Sugawa , Tetsuya Yano , Takeshi Imamura , Tsutomu Honma
发明人： Takashi Kenmoku , Etsuko Sugawa , Tetsuya Yano , Takeshi Imamura , Tsutomu Honma
IPC分类号： C12P11/00 , C12P7/62
CPC分类号： C08G63/6882 , C12P7/625 , C12P11/00
摘要： The present invention provides a method of effectively producing polyhydroxyalkanoate having an aromatic substituted residue in its monomer unit. In the method of producing polyhydroxyalkanoate by using microorganisms, microorganisms capable of producing polyhydroxyalkanoate are cultured in a culture medium containing at least one starting compound selected from the group consisting of substituted alkanes represented by formula (1) to produce polyhydroxyalkanoate having, in its molecule, at least one unit selected from the group consisting of 3-hydroxy-substituted alkanoate units represented by formula (2): R—(CH2)n—CH2—CH2—CH3 (1) wherein R represents a residue containing a substituted aromatic ring, and n represents any integer of 1 to 8; wherein R represents a residue containing a substituted aromatic ring, and n represents any integer of 1 to 8. In formulas (1) and (2), a residue R is as described in the specification.
摘要翻译：本发明提供了在其单体单元中有效制备具有芳族取代残基的聚羟基链烷酸酯的方法。在通过使用微生物制备聚羟基链烷酸酯的方法中，能够在含有选自由式（1）表示的取代烷烃中的至少一种起始化合物的培养基中培养能够产生聚羟基链烷酸酯的微生物，从而产生在其分子中具有的聚羟基链烷酸酯，选自由式（2）表示的3-羟基取代的链烷酸酯单元中的至少一个单元：<？in-line-formula description =“In-line Formulas”end =“lead”？> R-（CH （2）-CH 2 CH 2 CH 2 CH 2（1）其中，R表示含有取代芳环的残基，n表示1〜8的整数，n表示1〜8的整数。其中R表示含有取代芳环的残基，n表示1至8的任何整数。在式（1）和（2）中，残基R如说明书所述。

33. 发明授权

US06777153B2 POLYHYDROXYALKANOATE CONTAINING UNIT WITH THIENYL STRUCTURE IN THE SIDE CHAIN, PROCESS FOR ITS PRODUCTION, CHARGE CONTROL AGENT, TONER BINDER AND TONER WHICH CONTAIN THIS POLYHYDROXYALKANOATE, AND IMAGE-FORMING METHOD AND IMAGE-FORMING APPARATUS WHICH MAKE USE OF THE TONER 失效
标题翻译：含有三链体结构的聚羟基烷基酯单元，其链中具有三烯结构，其制备方法，充电控制剂，含有该聚羟基烷酸酯的调色剂和调色剂，以及使用该调色剂的成像方法和图像形成装置
公开(公告)号：US06777153B2
公开(公告)日：2004-08-17
申请号：US10105305
申请日：2002-03-26
申请人： Tetsuya Yano , Etsuko Sugawa , Takeshi Imamura , Tsutomu Honma , Takashi Kenmoku
发明人： Tetsuya Yano , Etsuko Sugawa , Takeshi Imamura , Tsutomu Honma , Takashi Kenmoku
IPC分类号： G03G900
CPC分类号： C08G63/6882 , C12P7/62 , G03G9/08755 , G03G9/08791 , Y10S435/874 , Y10S435/877
摘要： A polyhydroxyalkanoate characterized by having in the molecule a unit represented by Chemical Formula (1): wherein n may assume any one integral value within the range of from 1 to 8. Also disclosed are a process for producing the polyhydroxyalkanoate by the use of a microorganism having the ability to produce the polyhydroxyalkanoate and accumulate it in the bacterial body; a charge control agent, a toner binder and a toner which contain this polyhydroxyalkanoate; and an image-forming method and an image-forming apparatus which make use of the toner.
摘要翻译：特征在于在分子中具有由化学式（1）表示的单元的聚羟基链烷酸酯：其中n可以在1至8的范围内呈现任何一个整数值。还公开了通过使用微生物制备聚羟基链烷酸酯的方法具有生产聚羟基链烷酸酯并将其积聚在细菌体内的能力; 电荷控制剂，调色剂粘合剂和含有该聚羟基链烷酸酯的调色剂; 以及利用调色剂的图像形成方法和图像形成装置。

34. 发明授权

US06586562B2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same 失效
标题翻译：聚羟基链烷酸酯，其制备方法和用于其的微生物
公开(公告)号：US06586562B2
公开(公告)日：2003-07-01
申请号：US09748205
申请日：2000-12-27
申请人： Tsutomu Honma , Toyoko Kobayashi , Tetsuya Yano , Shin Kobayashi , Takeshi Imamura , Sakae Suda , Takashi Kenmoku
发明人： Tsutomu Honma , Toyoko Kobayashi , Tetsuya Yano , Shin Kobayashi , Takeshi Imamura , Sakae Suda , Takashi Kenmoku
IPC分类号： C08G6306
CPC分类号： C12P7/62 , C08G63/06 , C08G63/6822 , C08G63/6852 , Y10S435/874
摘要： A polyhydroxyalkanoate having a monomer unit composition represented by General Formula (1): AmB(1−m) (1) wherein A is represented by General Formula (2), B is at least one selected from the group consisting of monomer units represented by General Formula (3) or (4), and m has a value of 0.01 or larger and smaller than 1: wherein n has a value of 0 to 10, k has a value of 3 or 5, and R is at least one group selected from the group consisting of groups represented by General Formulae (5) to (7): in Formula (5) R1 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, —CN, —NO2, —CF3, —C2F5 and —C3F7; and q is an integer selected from 1 to 8; in Formula (6) R2 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, —CN, —NO2, —CF3, —C2F5 and —C3F7; and r is an integer selected from 1 to 8; in Formula (7) R3 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, —CN, —NO2, —CF3, —C2F5 and —C3F7; and s is an integer selected from 1 to 8. The efficient production methods are also provided.
摘要翻译：具有由通式（1）表示的单体单元组成的聚羟基链烷酸酯：其中A由通式（2）表示，B为选自由通式（3）或（4）表示的单体单元中的至少一种，，m的值为0.01以上且小于1，其中n为0〜10，k为3或5，R为选自由通式（5）〜（7）中，式（5）中，R 1为选自氢原子（H），卤素原子，-CN，-NO 2，-CF 3，-C 2 F 5和-C 3 F 7的基团。 q为选自1至8的整数; 在式（6）中，R 2是选自氢原子（H），卤素原子，-CN，-NO 2，-CF 3，-C 2 F 5和-C 3 F 7的基团; 并且r是选自1至8的整数; 在式（7）中，R 3是选自氢原子（H），卤素原子，-CN，-NO 2，-CF 3，-C 2 F 5和-C 3 F 7的基团; s是选自1至8的整数。还提供了有效的制备方法。

35. 发明申请

US20090061498A1 POLYHYDROXYALKANOATE-CONTAINING STRUCTURE AND MANUFACTURING METHOD THEREOF 失效
标题翻译：含聚羟基烷酸钾的结构及其制造方法
公开(公告)号：US20090061498A1
公开(公告)日：2009-03-05
申请号：US12177094
申请日：2008-07-21
申请人： Tsuyoshi Nomoto , Tetsuya Yano , Shinya Kozaki , Tsutomu Honma
发明人： Tsuyoshi Nomoto , Tetsuya Yano , Shinya Kozaki , Tsutomu Honma
IPC分类号： C12N11/02 , C08K3/04 , G03G9/093 , C12N11/14
CPC分类号： C12N9/1025 , C12N11/00 , C12P7/625 , Y10T428/2989
摘要： A method for manufacturing polyhydroxyalkanoate-containing structure, at least a part of a base material surface of the structure being coated with polyhydroxyalkanoate, the method comprises the steps of immobilizing a polyhydroxyalkanoate synthase on the base material surface, synthesizing, on the base material surface, polyhydroxyalkanoate using a 3-hydroxyacyl coenzyme A to become the substrate of the synthase and the synthase and coating at least a part of the base material surface with the synthesized polyhydroxyalkanoate, wherein the synthase contains an amino acid sequence capable of binding to the base material. A polyhydroxyalkanoate-containing structure, at least a part of a base material surface of the structure being coated with a polyhydroxyalkanoate, comprises the base material, a polyhydroxyalkanoate synthase immobilized on the base material surface, and the polyhydroxyalkanoate with which at least a part of the base material surface is coated, wherein the synthase contains an amino acid sequence capable of binding to the base material.
摘要翻译：一种制备聚羟基链烷酸酯结构的方法，所述结构的基材表面的至少一部分涂覆有聚羟基链烷酸酯，所述方法包括将聚羟基链烷酸酯合酶固定在基材表面上，在基材表面上合成，聚羟基链烷酸酯使用3-羟酰基辅酶A成为合成酶和合成酶的底物并用合成的聚羟基链烷酸酯涂覆至少一部分基材表面，其中合成酶含有能够与基材结合的氨基酸序列。一种含聚羟基链烷酸酯的结构，该结构的基材表面的至少一部分涂覆有聚羟基链烷酸酯，其包含基材，固定在基材表面上的聚羟基链烷酸酯合酶和至少一部分的聚羟基链烷酸酯基材表面被涂覆，其中合成酶含有能够结合基材的氨基酸序列。

36. 发明授权

US07267974B2 Polyhydroxyalkanoate synthesizing microorganism and process of producing polyhydroxyalkanoate using the same 失效
标题翻译：聚羟基链烷酸酯合成微生物和使用其制备聚羟基链烷酸酯的方法
公开(公告)号：US07267974B2
公开(公告)日：2007-09-11
申请号：US11340728
申请日：2006-01-27
申请人： Shinya Kozaki , Tsutomu Honma , Tetsuya Yano
发明人： Shinya Kozaki , Tsutomu Honma , Tetsuya Yano
IPC分类号： C12N1/24 , C12N1/21 , C12P17/00 , C12P11/00
CPC分类号： C12P7/625 , C12N1/20 , C12P17/00 , C12R1/38
摘要： Microorganisms showing higher productivity of unusual-polyhydroxyalkanoate (PHA) than ever by using an inexpensive substrate or under specific conditions are obtained from wild strains and mutant strains. The microorganisms are cultured with such substrates to synthesize an unusual-polyhydroxyalkanoate. The unusual-polyhydroxyalkanoate can be produced with high efficiency at low cost.
摘要翻译：通过使用廉价的底物或在特定条件下显示异常聚羟基链烷酸酯（PHA）的较高生产力的微生物从野生菌株和突变菌株获得。用这种底物培养微生物以合成异常聚羟基链烷酸酯。异常的聚羟基链烷酸酯可以以低成本高效率地生产。

37. 发明申请

US20070003975A1 Structured construct and producing method therefor 审中-公开
标题翻译：结构构造及其制造方法
公开(公告)号：US20070003975A1
公开(公告)日：2007-01-04
申请号：US10544942
申请日：2004-05-06
申请人： Takeshi Imamura , Tetsuya Yano , Tsutomu Honma , Shinya Kozaki , Tsuyoshi Nomoto , Akiko Tsuchitani
发明人： Takeshi Imamura , Tetsuya Yano , Tsutomu Honma , Shinya Kozaki , Tsuyoshi Nomoto , Akiko Tsuchitani
IPC分类号： C12P7/62 , G01N33/53 , B32B27/14
CPC分类号： C12N9/93 , C07K2319/23 , C09D167/04 , C12N11/08 , C12P7/625 , G01N33/54326 , G01N33/54393 , G01N2333/21 , G01N2333/245
摘要： There is provided a construct in which at least a part of the magnetic material is coated with a polyhydroxyalkanoate (PHA), and a method for producing a construct by immobilizing a PHA synthesizing enzyme on the surface of the magnetic material, thereby biosynthesizing and coating a PHA.
摘要翻译：提供了其中至少一部分磁性材料涂覆有聚羟基链烷酸酯（PHA）的构造，以及通过将PHA合成酶固定在磁性材料的表面上来生产构建体的方法，从而生物合成和涂覆 PHA。

38. 发明授权

US06951745B2 Polyhydroxyalkanoate-containing structure and manufacturing method thereof 失效
标题翻译：含聚羟基链烷酸酯的结构及其制造方法
公开(公告)号：US06951745B2
公开(公告)日：2005-10-04
申请号：US10191540
申请日：2002-07-10
申请人： Tsuyoshi Nomoto , Tetsuya Yano , Shinya Kozaki , Tsutomu Honma
发明人： Tsuyoshi Nomoto , Tetsuya Yano , Shinya Kozaki , Tsutomu Honma
IPC分类号： G03G9/09 , B41M5/00 , C07K7/08 , C07K17/14 , C08G63/90 , C09C3/10 , C09D11/02 , C09D11/037 , C09D11/322 , C12N9/10 , C12N11/00 , C12N15/09 , C12P7/62 , G02B5/20 , G02B5/22 , G03G9/087 , C12P7/16 , C12P11/00
CPC分类号： C12N9/1025 , C12N11/00 , C12P7/625 , Y10T428/2989
摘要： A method for manufacturing polyhydroxyalkanoate-containing structure, at least a part of a base material surface of the structure being coated with polyhydroxyalkanoate, the method comprises the steps of immobilizing a polyhydroxyalkanoate synthase on the base material surface, synthesizing, on the base material surface, polyhydroxyalkanoate using a 3-hydroxyacyl coenzyme A to become the substrate of the synthase and the synthase and coating at least a part of the base material surface with the synthesized polyhydroxyalkanoate, wherein the synthase contains an amino acid sequence capable of binding to the base material. A polyhydroxyalkanoate-containing structure, at least a part of a base material surface of the structure being coated with a polyhydroxyalkanoate, comprises the base material, a polyhydroxyalkanoate synthase immobilized on the base material surface, and the polyhydroxyalkanoate with which at least a part of the base material surface is coated, wherein the synthase contains an amino acid sequence capable of binding to the base material.
摘要翻译：一种制备聚羟基链烷酸酯结构的方法，所述结构的基材表面的至少一部分涂覆有聚羟基链烷酸酯，所述方法包括将聚羟基链烷酸酯合酶固定在基材表面上，在基材表面上合成，聚羟基链烷酸酯使用3-羟酰基辅酶A成为合成酶和合成酶的底物并用合成的聚羟基链烷酸酯涂覆至少一部分基材表面，其中合成酶含有能够与基材结合的氨基酸序列。一种含聚羟基链烷酸酯的结构，该结构的基材表面的至少一部分涂覆有聚羟基链烷酸酯，其包含基材，固定在基材表面上的聚羟基链烷酸酯合酶和至少一部分的聚羟基链烷酸酯基材表面被涂覆，其中合成酶含有能够结合基材的氨基酸序列。

39. 发明申请

US20050208635A1 Polyhydroxyalkanoate-containing structure and manufacturing method thereof 审中-公开
公开(公告)号：US20050208635A1
公开(公告)日：2005-09-22
申请号：US11119889
申请日：2005-05-03
申请人： Tsuyoshi Nomoto , Tetsuya Yano , Shinya Kozaki , Tsutomu Honma
发明人： Tsuyoshi Nomoto , Tetsuya Yano , Shinya Kozaki , Tsutomu Honma
IPC分类号： G03G9/09 , B41M5/00 , C07K7/08 , C07K17/14 , C08G63/90 , C09C3/10 , C09D11/02 , C09D11/037 , C09D11/322 , C12N9/10 , C12N11/00 , C12N15/09 , C12P7/62 , G02B5/20 , G02B5/22 , G03G9/087 , G03G9/00
CPC分类号： C12N9/1025 , C12N11/00 , C12P7/625 , Y10T428/2989
摘要： A method for manufacturing polyhydroxyalkanoate-containing structure, at least a part of a base material surface of the structure being coated with polyhydroxyalkanoate, the method comprises the steps of immobilizing a polyhydroxyalkanoate synthase on the base material surface, synthesizing, on the base material surface, polyhydroxyalkanoate using a 3-hydroxyacyl coenzyme A to become the substrate of the synthase and the synthase and coating at least a part of the base material surface with the synthesized polyhydroxyalkanoate, wherein the synthase contains an amino acid sequence capable of binding to the base material. A polyhydroxyalkanoate-containing structure, at least a part of a base material surface of the structure being coated with a polyhydroxyalkanoate, comprises the base material, a polyhydroxyalkanoate synthase immobilized on the base material surface, and the polyhydroxyalkanoate with which at least a part of the base material surface is coated, wherein the synthase contains an amino acid sequence capable of binding to the base material.

40. 发明授权

US07615233B2 Particulate construct comprising polyhydroxyalkanoate and method for producing it 失效
标题翻译：包含聚羟基链烷酸酯的颗粒构造物及其生产方法
公开(公告)号：US07615233B2
公开(公告)日：2009-11-10
申请号：US10191563
申请日：2002-07-10
申请人： Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Tsutomu Honma
发明人： Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Tsutomu Honma
IPC分类号： A01N25/34
CPC分类号： A61K8/11 , A61K8/35 , A61K9/5031 , A61K47/6925 , A61K49/223 , A61K2800/412 , A61Q17/04 , B01J13/04 , B01J13/06 , B01J13/14 , Y02A50/473
摘要： The invention provides a particulate construct comprising a polyhydroxyalkanoate to serve as microcapsules containing a drug, and serving a slow releasing preparation not associated with a practically unacceptable initial burst release but showing a practically acceptable zero-order release for a certain period and a producing method for such particulate construct, and a slow releasing preparation of a high drug content capable of stably incorporating the drug in the particulate construct such as microcapsules, and a producing method for such preparation.
摘要翻译：本发明提供了一种包含聚羟基链烷酸酯的颗粒构造物，用作含有药物的微胶囊，并且用于与实际上不可接受的初始爆发释放无关的缓释制剂，但在一定时间内显示出实际可接受的零级释放，这种颗粒构造物，以及能够稳定地将药物并入微粒构造物如微胶囊中的高药物含量的缓释制剂及其制备方法。

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