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31. 发明申请

US20120101519A1 POROUS VASCULAR CLOSURE PLUG WITH STARCH POWDER 审中-公开
标题翻译：多孔血管闭塞插管
公开(公告)号：US20120101519A1
公开(公告)日：2012-04-26
申请号：US13278853
申请日：2011-10-21
申请人： Jason P. Hill , Mark L. Jenson , Haitao Zhang , Kai Wang , Pu Zhou
发明人： Jason P. Hill , Mark L. Jenson , Haitao Zhang , Kai Wang , Pu Zhou
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00601 , A61B2017/00654 , A61B2017/00898 , A61L24/0036 , A61L24/0042 , A61L24/0094 , A61L2400/04 , C08L3/00
摘要： The disclosure provides a composite plug for vascular closure including a hemostatic material, and a method of manufacturing the composite plug including a hemostatic material. The composite plug may comprise one or more materials having varying porosity, density, or composition, and may include a powdered hemostatic material.
摘要翻译：本公开提供了一种用于血管闭合的复合塞，包括止血材料，以及制造包括止血材料的复合塞的方法。复合塞子可以包括具有不同孔隙率，密度或组成的一种或多种材料，并且可以包括粉末状止血材料。

32. 发明授权

US06814561B2 Apparatus and method for extrusion of thin-walled tubes 失效
标题翻译：用于挤出薄壁管的装置和方法
公开(公告)号：US06814561B2
公开(公告)日：2004-11-09
申请号：US10012825
申请日：2001-10-30
申请人： James Venditti , Howard Wolek , Alice Wong , David J. Sogard , Jason P. Hill , Timothy S. Girton , Christopher B. Brodeur
发明人： James Venditti , Howard Wolek , Alice Wong , David J. Sogard , Jason P. Hill , Timothy S. Girton , Christopher B. Brodeur
IPC分类号： B29C4720
CPC分类号： B29C47/54 , B29C45/531 , B29C47/0004 , B29C47/0023 , B29C47/003 , B29C47/0042 , B29K2027/18 , B29K2105/04 , B29L2023/007 , Y10T428/1352 , Y10T428/139
摘要： The present invention provides an apparatus and method for manufacturing polymeric thin-walled tubular members, which are well-suited for use as vascular grafts. The apparatus of the present invention enables extrusion of a tubular member having an extremely thin wall thickness so as to facilitate passage through tortuous vascular passageways. The apparatus achieves uniform wall thickness in a tubular member by establishing and maintaining axial alignment of a ram having a concentrically disposed guide rod therein with a die supported in concentric relation to the guide rod.
摘要翻译：本发明提供一种用于制造聚合物薄壁管状构件的装置和方法，其非常适合用作血管移植物。本发明的装置能够挤出具有非常薄的壁厚的管状构件，以便于通过曲折的血管通道。该装置通过建立并保持其中具有同心设置的导杆的冲头的轴向对准，并且与导向件同心地支撑模具，在管状构件中实现均匀的壁厚。

33. 发明申请

US20090030512A1 Circulatory valve, system and method 有权
标题翻译：循环阀，系统和方法
公开(公告)号：US20090030512A1
公开(公告)日：2009-01-29
申请号：US11881220
申请日：2007-07-26
申请人： Joseph M. Thielen , Jason P. Hill , Mark L. Jenson , William J. Drasler
发明人： Joseph M. Thielen , Jason P. Hill , Mark L. Jenson , William J. Drasler
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2/2475 , A61F2/82 , A61F2/95 , A61F2002/9665 , A61F2210/0076 , A61F2230/0013
摘要： Apparatuses, systems, and methods for use in a vascular system. The apparatus include a circulatory valve having a valve frame in which frame members define frame cells. Frame cells include joints in opposing relationship, where the joints transition from a first stable equilibrium state through an unstable equilibrium state to a second stable equilibrium state as the joints are drawn towards each other.
摘要翻译：用于血管系统的装置，系统和方法。该装置包括具有阀框架的循环阀，其中框架构件限定框架单元。框架单元包括相对关系的关节，其中当关节被拉向彼此时，关节从第一稳定平衡状态转变到不稳定平衡状态到第二稳定平衡状态。

34. 发明申请

US20080269877A1 Systems and methods for valve delivery 审中-公开
标题翻译：阀门输送系统和方法
公开(公告)号：US20080269877A1
公开(公告)日：2008-10-30
申请号：US12012897
申请日：2008-02-05
申请人： Mark L. Jenson , William J. Drasler , Jason P. Hill , Joseph M. Thielen
发明人： Mark L. Jenson , William J. Drasler , Jason P. Hill , Joseph M. Thielen
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/013 , A61F2/243 , A61F2/2433 , A61F2/2475 , A61F2002/018 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2230/0006 , A61F2230/0069 , A61F2250/0059
摘要： A system having an elongate delivery catheter, an elongate mesh body including an expandable region positioned around at least a portion of the elongate delivery catheter, a retractable member that extends through the elongate delivery catheter to connect to the elonga'te mesh body, where the retractable member moves to radially expand the expandable region of the elongate mesh body from an undeployed state to an intermediate state. The system also includes a valve positioned around at least a portion of the elongate delivery catheter position, and a filter positioned around at least a portion of the elongate delivery catheter to filter and control fluid flow.
摘要翻译：一种具有细长递送导管的系统，细长网状体，其包括位于所述细长递送导管的至少一部分周围的可扩张区域;伸缩构件，其延伸穿过所述细长递送导管以连接到所述伸长网状体，伸缩构件移动以使细长网状体的可扩张区域从未部署状态向中间状态径向膨胀。该系统还包括位于细长输送导管位置的至少一部分周围的阀，以及围绕细长输送导管的至少一部分定位以过滤和控制流体流动的过滤器。

35. 发明申请

US20110066181A1 TISSUE PUNCTURE CLOSURE DEVICE 失效
标题翻译：组织式关闭装置
公开(公告)号：US20110066181A1
公开(公告)日：2011-03-17
申请号：US12948569
申请日：2010-11-17
申请人： Mark L. Jenson , Jason P. Hill , Joseph Thielen , Michael J. Pikus , Joel Groff , David M. Hill
发明人： Mark L. Jenson , Jason P. Hill , Joseph Thielen , Michael J. Pikus , Joel Groff , David M. Hill
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/0467 , A61B2017/00004 , A61B2017/00455 , A61B2017/00623 , A61B2017/00637 , A61B2017/00654 , A61B2017/00663 , A61B2017/00672 , A61B2017/00898 , A61B2090/0801
摘要： The present disclosure relates generally to methods and devices for closing and/or sealing an opening in a vessel wall and/or an adjacent tissue tract. In one illustrative embodiment, a device is provided for delivering and deploying an anchor, plug, filament, and locking element adjacent to the opening in the vessel wall and/or tissue tract.
摘要翻译：本公开一般涉及关闭和/或密封血管壁和/或相邻组织道中的开口的方法和装置。在一个说明性实施例中，提供了用于递送和展开与容器壁和/或组织道中的开口相邻的锚，栓，细丝和锁定元件的装置。

36. 发明申请

US20080065150A1 Method and Apparatus for Promoting Hemostasis of a Blood Vessel Puncture 有权
标题翻译：促进血管穿刺止血的方法和装置
公开(公告)号：US20080065150A1
公开(公告)日：2008-03-13
申请号：US11531143
申请日：2006-09-12
申请人： William Drasler , Mark Jenson , Jason P. Hill
发明人： William Drasler , Mark Jenson , Jason P. Hill
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00641
摘要： An apparatus for promoting hemostasis of a puncture formed in a blood vessel accessible through an incision tract. The apparatus includes a distal balloon having a contacted position, in which a profile of the distal balloon is sized for insertion through the blood vessel puncture, an expanded position, in which the distal balloon profile prevents passage through the blood vessel puncture. The apparatus also includes a proximal balloon spaced by a predetermined initial distance from the distal balloon and having a contracted position, in which a profile of the proximal balloon is sized for insertion through the incision tract, and an expanded position, in which the proximal balloon profile blocks passage through the blood vessel puncture. The apparatus further includes at least one catheter coupling the distal and proximal balloons to a source of pressurized fluid to selectively actuate the distal and proximal balloons between the contracted and expanded positions. And, the apparatus includes at least one rigid positioner associated with the at least one catheter to facilitate movement of the distal and proximal balloons proximally through the incision tract. The catheter has a flexible wall portion extending proximally of the distal and proximal balloons to facilitate everting of the distal and proximal balloons as the catheter is proximally withdrawn from the incision tract.
摘要翻译：一种用于促进形成在通过切口可通过的血管中形成的穿刺止血的装置。该装置包括具有接触位置的远端球囊，其中远端球囊的轮廓的尺寸设置成插入通过血管穿刺，扩张位置，其中远侧球囊形状防止通过血管穿刺。该装置还包括与远端球囊隔开预定的初始距离并且具有收缩位置的近端球囊，其中近端球囊的轮廓的尺寸被设计成用于插入通过切开管道，以及扩张位置，其中近端球囊轮廓块通过血管穿刺。该装置还包括至少一个导管，其将远端和近端气囊联接到加压流体源，以选择性地致动收缩和扩张位置之间的远端和近端气囊。并且，该装置包括与至少一个导管相关联的至少一个刚性定位器，以便于远端和近端球囊向近侧移动通过切口。导管具有在远端和近端气囊的近侧延伸的柔性壁部分，以便当导管从切开道向近端退出时便于远端和近端气囊的远端。

37. 发明授权

US06638468B1 Method of reducing the wall thickness of a PTFE tube 有权
标题翻译：降低PTFE管壁厚的方法
公开(公告)号：US06638468B1
公开(公告)日：2003-10-28
申请号：US09748417
申请日：2000-12-26
申请人： Jason P. Hill , James R. Lininger , Brian J. Brown
发明人： Jason P. Hill , James R. Lininger , Brian J. Brown
IPC分类号： B29B1110
CPC分类号： B29C67/0014 , B29C55/24
摘要： A thin wall PTFE tube is formed from an extruded green tube. The PTFE tube includes an inner tubular surface and an opposed outer tubular surface defining a tubular wall of a first thickness. The tubular wall is compressed to uniformly reduce the wall-thickness and circumferentially orient the tube. The PTFE tube is positioned over a first elongate roller with the inner tubular surface being in contact therewith. A second roller is positioned against the outer tubular surface of the PTFE tube. The pair of rollers are counter rotated so as to circumferentially compress the tubular wall between the rollers. This results in the uniform reduction in the tubular wall from the first thickness to a lesser second thickness and a circumferential orientation otherwise not occurring in an extruded PTFE paste extrusion.
摘要翻译：由挤出的绿色管形成薄壁PTFE管。 PTFE管包括内部管状表面和限定具有第一厚度的管状壁的相对的外部管状表面。管状壁被压缩以均匀地减小壁厚并且周向地定向管。 PTFE管定位在第一细长辊上，内管表面与其接触。第二辊定位在PTFE管的外管表面上。一对辊被反向旋转，以便周向地压缩辊之间的管状壁。这导致管状壁从第一厚度均匀地减小到较小的第二厚度，并且在挤出的PTFE浆料挤出中不发生圆周取向。

38. 发明授权

US08758402B2 Tissue puncture closure device 失效
标题翻译：组织穿刺闭合装置
公开(公告)号：US08758402B2
公开(公告)日：2014-06-24
申请号：US13253497
申请日：2011-10-05
申请人： Mark L. Jenson , Jason P. Hill
发明人： Mark L. Jenson , Jason P. Hill
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00398 , A61B2017/0046 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/00663 , A61B2017/00672 , A61B2017/00734
摘要： The present disclosure relates generally to methods and devices for closing and/or sealing an opening in a vessel wall and/or an adjacent tissue tract. In one illustrative embodiment, a device is provided for delivering and deploying an anchor, plug, suture, and/or locking element adjacent to the opening in the vessel wall and/or tissue tract.
摘要翻译：本公开一般涉及关闭和/或密封血管壁和/或相邻组织道中的开口的方法和装置。在一个示例性实施例中，提供了用于递送和展开与容器壁和/或组织道中的开口相邻的锚，塞，缝合线和/或锁定元件的装置。

39. 发明授权

US08529598B2 Tissue puncture closure device 失效
标题翻译：组织穿刺闭合装置
公开(公告)号：US08529598B2
公开(公告)日：2013-09-10
申请号：US12948569
申请日：2010-11-17
申请人： Mark L. Jenson , Jason P. Hill , Joseph Thielen , Michael J. Pikus , Joel Groff , David Hill
发明人： Mark L. Jenson , Jason P. Hill , Joseph Thielen , Michael J. Pikus , Joel Groff , David Hill
IPC分类号： A61B17/08 , A61M5/315 , A61M31/00
CPC分类号： A61B17/0057 , A61B17/0467 , A61B2017/00004 , A61B2017/00455 , A61B2017/00623 , A61B2017/00637 , A61B2017/00654 , A61B2017/00663 , A61B2017/00672 , A61B2017/00898 , A61B2090/0801
摘要： The present invention relates generally to methods and devices for closing and/or sealing an opening in a vessel wall and/or an adjacent tissue tract. In one illustrative embodiment, a device is provided for delivering and deploying an anchor, plug, filament, and locking element adjacent to the opening in the vessel wall and/or tissue tract.
摘要翻译：本发明一般涉及关闭和/或密封血管壁和/或相邻组织道中的开口的方法和装置。在一个说明性实施例中，提供了用于递送和展开与容器壁和/或组织道中的开口相邻的锚，栓，细丝和锁定元件的装置。

40. 发明申请

US20120158044A1 TISSUE PUNCTURE CLOSURE DEVICE 失效
标题翻译：组织式关闭装置
公开(公告)号：US20120158044A1
公开(公告)日：2012-06-21
申请号：US13253497
申请日：2011-10-05
申请人： Mark L. Jenson , Jason P. Hill
发明人： Mark L. Jenson , Jason P. Hill
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00398 , A61B2017/0046 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/00663 , A61B2017/00672 , A61B2017/00734
摘要： The present disclosure relates generally to methods and devices for closing and/or sealing an opening in a vessel wall and/or an adjacent tissue tract. In one illustrative embodiment, a device is provided for delivering and deploying an anchor, plug, suture, and/or locking element adjacent to the opening in the vessel wall and/or tissue tract.
摘要翻译：本公开一般涉及关闭和/或密封血管壁和/或相邻组织道中的开口的方法和装置。在一个示例性实施例中，提供了用于递送和展开与容器壁和/或组织道中的开口相邻的锚，塞，缝合线和/或锁定元件的装置。

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