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31. 发明授权

US09591879B2 Methods and apparatus for ear protection 有权
标题翻译：耳朵保护方法和装置
公开(公告)号：US09591879B2
公开(公告)日：2017-03-14
申请号：US13168618
申请日：2011-06-24
申请人： Kenneth J. Michlitsch , Jane P. Bearinger
发明人： Kenneth J. Michlitsch , Jane P. Bearinger
IPC分类号： A61F11/06 , A41D13/05 , A61F11/14 , A45D44/12
CPC分类号： A41D13/05 , A45D44/12 , A61F11/14
摘要： Methods and apparatus are provided for protecting the external ear from the elements, heat, cold, wind, rain and/or snow. In some embodiments, an ear protector comprises a conforming anchor with an opening through which the external ear may be passed. The ear protector further comprises an insulating outer covering that, in combination with the anchor, forms the ear protector with a chamber positioned between the outer covering and the anchor. During use, the chamber is configured to receive the external ear, with the anchor's opening conformably positioned in proximity to at least a portion of the ear's root. The perimeter of the conforming anchor's opening resiliently deforms during passage of the external ear through the opening and into the chamber, and then conforms to the geometry of at least a portion of the ear root in order to securely and comfortably maintain the ear protector in position over the external ear without additional external support. The conforming anchor preferably is fabricated from a closed cell foamed elastomer.
摘要翻译：提供了用于保护外耳免受元件，热，冷，风，雨和/或雪的方法和装置。在一些实施例中，耳朵保护器包括具有外耳道可穿过的开口的一致的锚。耳朵保护器还包括绝缘外覆盖物，其与锚固件组合形成具有定位在外覆盖物和锚固件之间的腔室的护耳器。在使用期间，腔室被构造成接收外耳，其中锚的开口顺应地定位在耳朵根部的至少一部分附近。在外耳道通过开口并进入腔室时，适形锚的开口的周边弹性变形，然后符合耳根的至少一部分的几何形状，以便牢固和舒适地将耳朵保护器保持在适当位置无需外部支持。优选地，适形锚固件由闭孔发泡弹性体制成。

32. 发明授权

US08425553B2 Autologous wound sealing apparatus 有权
标题翻译：自动伤口密封装置
公开(公告)号：US08425553B2
公开(公告)日：2013-04-23
申请号：US13615551
申请日：2012-09-13
申请人： Kenneth J. Michlitsch
发明人： Kenneth J. Michlitsch
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00491 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/00672
摘要： The apparatus is provided for sealing a vascular puncture tract by forming the autologous plug within the puncture tract, and extruding that plug into the puncture tract. The apparatus of the present invention forms an autologous blood plug by drawing blood into the apparatus from a vessel, mixing a blood congealing agent with the drawn blood, and ejecting a plug formed from the clotted blood within the puncture tract. Also provided are various closure elements to isolate the drawn blood from the vessel during mixture with the blood congealing agent, and to facilitate placement of the apparatus relative to the vessel.
摘要翻译：该装置用于通过在穿刺管内形成自体塞子并将该塞子挤压到穿刺管中来密封血管穿刺道。本发明的装置通过从血管中将血液吸入装置，将血液凝固剂与抽取的血液混合，并在穿刺管内喷出由凝血血液形成的塞子，形成自体血栓。还提供了各种封闭元件，以在与血液凝结剂混合期间将抽取的血液与血管隔离，并且便于相对于血管的装置放置。

33. 发明授权

US08398630B2 Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen 有权
公开(公告)号：US08398630B2
公开(公告)日：2013-03-19
申请号：US13620173
申请日：2012-09-14
申请人： Denise Demarais , Hanson Gifford, III , Mark Deem , Nicolas Zadno , Benjamin J. Clark , Andrew Wu , Kenneth J. Michlitsch
发明人： Denise Demarais , Hanson Gifford, III , Mark Deem , Nicolas Zadno , Benjamin J. Clark , Andrew Wu , Kenneth J. Michlitsch
IPC分类号： A61B18/12
摘要： Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided.

34. 发明授权

US08323311B2 Autologous wound sealing apparatus 有权
标题翻译：自动伤口密封装置
公开(公告)号：US08323311B2
公开(公告)日：2012-12-04
申请号：US12853139
申请日：2010-08-09
申请人： Kenneth J. Michlitsch
发明人： Kenneth J. Michlitsch
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00491 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/00672
摘要： The apparatus is provided for sealing a vascular puncture tract by forming the autologous plug within the puncture tract, and extruding that plug into the puncture tract. The apparatus of the present invention forms an autologous blood plug by drawing blood into the apparatus from a vessel, mixing a blood congealing agent with the drawn blood, and ejecting a plug formed from the clotted blood within the puncture tract. Also provided are various closure elements to isolate the drawn blood from the vessel during mixture with the blood congealing agent, and to facilitate placement of the apparatus relative to the vessel.
摘要翻译：该装置用于通过在穿刺管内形成自体塞子并将该塞子挤压到穿刺管中来密封血管穿刺道。本发明的装置通过从血管中将血液吸入装置，将血液凝固剂与抽取的血液混合，并在穿刺管内喷出由凝血血液形成的塞子，形成自体血栓。还提供了各种封闭元件，以在与血液凝结剂混合期间将抽取的血液与血管隔离，并且便于相对于血管的装置放置。

35. 发明申请

US20120296348A1 APPARATUS FOR MANIPULATING AND SECURING TISSUE 有权
标题翻译：用于操作和安全组织的装置
公开(公告)号：US20120296348A1
公开(公告)日：2012-11-22
申请号：US13491273
申请日：2012-06-07
申请人： Vahid Saadat , Richard C. Ewers , Cang C. Laduca , Robert A. Vaughan , Chris Rothe , Kenneth J. Michlitsch
发明人： Vahid Saadat , Richard C. Ewers , Cang C. Laduca , Robert A. Vaughan , Chris Rothe , Kenneth J. Michlitsch
IPC分类号： A61B17/04
CPC分类号： A61F5/0086 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0483 , A61B17/0487 , A61B17/06 , A61B17/06066 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/12013 , A61B17/1285 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488
摘要： Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably dispose through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.
摘要翻译：本文描述了用于操纵和固定组织的装置。在组织折叠在患者身体内部时，组织操作组件通常可以具有细长的管状构件，可滑动地配置穿过管状构件的接合构件和适于经由螺旋构件接合组织的远端，组织稳定构件所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。稳定构件可以适于相对于细长管状构件的纵向轴线成角度。此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

36. 发明申请

US20110200171A1 METHODS AND APPARATUS FOR RENAL NEUROMODULATION VIA STEREOTACTIC RADIOTHERAPY 审中-公开
标题翻译：通过立体放射治疗进行肾神经调节的方法和装置
公开(公告)号：US20110200171A1
公开(公告)日：2011-08-18
申请号：US13009748
申请日：2011-01-19
申请人： Robert J. Beetel , Neil C. Barman , Benjamin J. Clark , Paul Friedrichs , Kenneth J. Michlitsch , Karun D. Naga , Andrew Wu , Denise Zarins
发明人： Robert J. Beetel , Neil C. Barman , Benjamin J. Clark , Paul Friedrichs , Kenneth J. Michlitsch , Karun D. Naga , Andrew Wu , Denise Zarins
IPC分类号： A61N5/10
CPC分类号： A61N5/1042 , A61B6/506 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61N5/1067 , A61N7/02 , A61N2005/1061
摘要： The present disclosure describes methods and apparatus for renal neuromodulation via stereotactic radiotherapy for the treatment of hypertension, heart failure, chronic kidney disease, diabetes, insulin resistance, metabolic disorder or other ailments. Renal neuromodulation may be achieved by locating renal nerves and then utilizing stereotactic radiotherapy to expose the renal nerves to a radiation dose sufficient to reduce neural activity. A neural location element may be provided for locating target renal nerves, and a stereotactic radiotherapy system may be provided for exposing the located renal nerves to a radiation dose sufficient to reduce the neural activity, with reduced or minimized radiation exposure in adjacent tissue. Renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as at pre-ganglionic positions.
摘要翻译：本公开描述了通过立体定向放射治疗高血压，心力衰竭，慢性肾脏疾病，糖尿病，胰岛素抵抗，代谢紊乱或其它疾病的肾神经调节的方法和装置。肾神经调节可以通过定位肾神经，然后利用立体定向放射治疗来将肾神经暴露于足以减少神经活动的辐射剂量来实现。可以提供用于定位目标肾神经的神经定位元件，并且可以提供立体定向放射治疗系统，用于将位于所述肾神经的辐射剂量暴露于足以减少或最小化相邻组织中的辐射暴露的神经活动的辐射剂量。肾神经可能位于神经节水平和/或神经节后位置以及神经节前位置。

37. 发明申请

US20100249773A1 HANDLE ASSEMBLIES FOR INTRAVASCULAR TREATMENT DEVICES AND ASSOCIATED SYSTEMS AND METHODS 有权
标题翻译：用于静脉内治疗装置和相关系统和方法的手柄组件
公开(公告)号：US20100249773A1
公开(公告)日：2010-09-30
申请号：US12759641
申请日：2010-04-13
申请人： Benjamin J. Clark , William R. George , Kenneth J. Michlitsch , John Paul Sam , Erik Thai , Andrew Wu
发明人： Benjamin J. Clark , William R. George , Kenneth J. Michlitsch , John Paul Sam , Erik Thai , Andrew Wu
IPC分类号： A61F7/12 , A61B18/08
CPC分类号： A61B18/08 , A61B34/74 , A61B2017/003 , A61B2018/00916
摘要： The present disclosure comprises handle assemblies for intravascular treatment devices. In one embodiment, a handle assembly comprises an actuator for deflecting a distal region of an intravascular treatment device. In one embodiment, a handle assembly comprises a rotator for rotating an intravascular treatment device independently of the handle assembly. In one embodiment, a handle assembly comprises a rotation limiting element for limiting independent rotation of an intravascular treatment device relative to the handle assembly. Methods and systems for intravascular delivery, deflection and placement of an intravascular treatment device via a handle assembly of the present invention are also provided.
摘要翻译：本公开包括用于血管内治疗装置的手柄组件。在一个实施例中，手柄组件包括用于偏转血管内治疗装置的远侧区域的致动器。在一个实施例中，手柄组件包括用于独立于手柄组件旋转血管内治疗装置的旋转器。在一个实施例中，手柄组件包括用于限制血管内治疗装置相对于手柄组件的独立旋转的旋转限制元件。还提供了通过本发明的手柄组件进行血管内递送，偏转和放置血管内治疗装置的方法和系统。

38. 发明授权

US07695493B2 System for optimizing anchoring force 有权
标题翻译：优化锚固力的系统
公开(公告)号：US07695493B2
公开(公告)日：2010-04-13
申请号：US10865736
申请日：2004-06-09
申请人： Vahid Saadat , Richard C. Ewers , Tracy D. Maahs , Alexander Khairkhahan , Kenneth J. Michlitsch
发明人： Vahid Saadat , Richard C. Ewers , Tracy D. Maahs , Alexander Khairkhahan , Kenneth J. Michlitsch
IPC分类号： A61B17/08 , A61D1/00
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0644 , A61B2017/00867 , A61B2017/0454 , A61B2017/0464 , A61B2017/0496 , A61B2017/06052 , A61B2090/037
摘要： Systems for optimizing anchoring force are described herein. In securing tissue folds, over-compression of the tissue directly underlying the anchors is avoided by utilizing tissue anchors having expandable arms configured to minimize contact area between the anchor and tissue. When the anchor is in its expanded configuration, a load is applied to the anchor until it is optimally configured to accommodate a range of deflections while the anchor itself exerts a substantially constant force against the tissue. Various devices, e.g., stops, spring members, fuses, strain gauges, etc., can be used to indicate when the anchor has been deflected to a predetermined level within the optimal range. Moreover, other factors to affect the anchor characteristics include, e.g., varying the number of arms or struts of the anchor, positioning of the arms, configuration of the arms, the length of the collars, etc.
摘要翻译：这里描述了用于优化锚固力的系统。在固定组织褶皱时，通过利用具有可扩张臂的组织锚来避免直接位于锚固件正下方的组织的过度压缩，所述组织锚构造成使锚和组织之间的接触面积最小化。当锚固件处于其膨胀构型时，将负载施加到锚固件，直到其被最佳地构造成适应一定范围的偏转，同时锚固件本身对组织施加基本恒定的力。可以使用各种装置，例如止动件，弹簧构件，保险丝，应变计等来指示锚固件何时被偏转到最佳范围内的预定水平。此外，影响锚固特征的其他因素包括例如改变锚的臂或支柱的数量，臂的定位，臂的构型，套环的长度等。

39. 发明申请

US20160000498A1 BALLOON CATHETER APPARATUSES FOR RENAL DENERVATION 有权
标题翻译：用于肾功能衰竭的气囊导管装置
公开(公告)号：US20160000498A1
公开(公告)日：2016-01-07
申请号：US14676649
申请日：2015-04-01
申请人： Denise Zarins , Hanson Gifford, III , Mark Deem , Nicolas Zadno , Benjamin J. Clark , Andrew Wu , Kenneth J. Michlitsch
发明人： Denise Zarins , Hanson Gifford, III , Mark Deem , Nicolas Zadno , Benjamin J. Clark , Andrew Wu , Kenneth J. Michlitsch
IPC分类号： A61B18/14 , A61B18/12
CPC分类号： A61B18/1492 , A61B18/1206 , A61B18/18 , A61B2018/00023 , A61B2018/00077 , A61B2018/0016 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00648 , A61B2018/00791 , A61B2018/00875 , A61B2018/124 , A61B2018/1435 , A61B2018/1465 , A61N1/0551 , A61N1/32 , A61N1/327 , A61N1/36007 , A61N7/022
摘要： Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided.
摘要翻译：提供了用于不间断地周围处理体腔的方法和装置。装置可以定位在患者的体腔内，并且可以在第一纵向和角位置处递送能量，以在第一位置处产生小于整个圆周的处理区域。该装置还可以在体腔内的一个或多个附加的纵向和角度位置处递送能量，以在一个或多个附加位置处创建小于整个圆周处理区域，该一个或多个附加位置从第一处理区域纵向和角度偏移。第一处理区和一个或多个另外的处理区的叠置限定非连续的圆周处理区而不形成连续的周向损伤。提供了用于实现这种非连续圆周处理的方法和装置的各种实施例。

40. 发明授权

US09023037B2 Balloon catheter apparatus for renal neuromodulation 有权
标题翻译：气球导管装置用于肾神经调节
公开(公告)号：US09023037B2
公开(公告)日：2015-05-05
申请号：US13868426
申请日：2013-04-23
申请人： Denise Zarins , Hanson Gifford, III , Mark Deem , Nicolas Zadno , Benjamin J. Clark , Andrew Wu , Kenneth J. Michlitsch
发明人： Denise Zarins , Hanson Gifford, III , Mark Deem , Nicolas Zadno , Benjamin J. Clark , Andrew Wu , Kenneth J. Michlitsch
IPC分类号： A61B18/12 , A61B18/18 , A61N1/32 , A61N1/36 , A61B18/14 , A61N1/05 , A61N7/02 , A61B18/00
CPC分类号： A61B18/1492 , A61B18/1206 , A61B18/18 , A61B2018/00023 , A61B2018/00077 , A61B2018/0016 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00648 , A61B2018/00791 , A61B2018/00875 , A61B2018/124 , A61B2018/1435 , A61B2018/1465 , A61N1/0551 , A61N1/32 , A61N1/327 , A61N1/36007 , A61N7/022
摘要： Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided.
摘要翻译：提供了用于不间断地周围处理体腔的方法和装置。装置可以定位在患者的体腔内，并且可以在第一纵向和角位置处递送能量，以在第一位置处产生小于整个圆周的处理区域。该装置还可以在体腔内的一个或多个附加的纵向和角度位置处递送能量，以在一个或多个附加位置处创建小于整个圆周处理区域，该一个或多个附加位置从第一处理区域纵向和角度偏移。第一处理区和一个或多个另外的处理区的叠置限定非连续的圆周处理区而不形成连续的周向损伤。提供了用于实现这种非连续圆周处理的方法和装置的各种实施例。

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