专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

US06258825B1 2-oxoimidazole derivatives 有权
标题翻译： 2-氧代咪唑衍生物
公开(公告)号：US06258825B1
公开(公告)日：2001-07-10
申请号：US09424114
申请日：1999-11-19
申请人： Satoshi Ozaki , Hiroshi Kawamoto , Yoshiki Ito , Kaori Hirano , Kyoko Hayashi , Yoshikazu Iwasawa
发明人： Satoshi Ozaki , Hiroshi Kawamoto , Yoshiki Ito , Kaori Hirano , Kyoko Hayashi , Yoshikazu Iwasawa
IPC分类号： A61K31454
CPC分类号： C07D401/04 , C07D403/04 , C07D451/06
摘要： The present invention relates to a compound represented by Formula [I] wherein represents an aromatic carbo- or heterocyclic ring which may have a substituent; Cy represents a mono-, bi- or tricyclic aliphatic carbocyclic group having 3 to 20 carbon atoms, which may have a substituent; represents a mono- or bicyclic aliphatic nitrogen-containing heterocyclic group having 3 to 14 carbon atoms, which may have a substituent; R1 represents a hydrogen atom, a lower alkenyl group, a lower alkynyl group, a cyclo(lower alkyl) group, an amino group, a lower alkylamino group, a di(lower alkyl)-amino group, a hydroxyl group, a lower alkoxy group, a carboxyl group, a lower alkoxycarbonyl group, a carbamoyl group, a lower alkylcarbamoyl group or a di(lower alkyl)carbamoyl group, or a lower alkyl group which may have a substituent; and R2 represents a hydrogen atom or a lower alkyl group, a salt or ester thereof, a production process for the same, and an analgesic, a reliever against tolerance to a narcotic analgesic represented by morphine, a reliever against dependence on a narcotic analgesic represented by morphine, an analgesic enhancer, an antiobestic, a drug for ameliorating brain function, a remedy for schizophrenia, a remedy for Parkinsonism, a remedy for chorea, an antidepressant, a remedy for diabetes insipidus, a remedy for polyuria, or a remedy for hypotension, comprising an effective ingredient of the same.
摘要翻译：本发明涉及由式[I]表示的化合物，其表示可具有取代基的芳族碳 - 或杂环; Cy表示可具有取代基的碳原子数为3〜20的单环，二环或三环脂肪族碳环基，表示可具有取代基的碳原子数为3〜14的单环或二环脂族含氮杂环基， ; R1表示氢原子，低级烯基，低级炔基，环（低级烷基），氨基，低级烷基氨基，二（低级烷基） - 氨基，羟基，低级烷氧基羧基，低级烷氧基羰基，氨基甲酰基，低级烷基氨基甲酰基或二（低级烷基）氨基甲酰基或可以具有取代基的低级烷基; 并且R 2表示氢原子或低级烷基，其盐或酯，其制备方法，以及止痛剂，对由吗啡代表的麻醉止痛剂的耐受性的缓解剂，对依赖麻醉止痛剂的缓解剂吗啡，镇痛增强剂，抗胆碱药，用于改善脑功能的药物，精神分裂症的治疗方法，帕金森综合征的补救措施，舞蹈病的补救措施，抗抑郁药，尿崩症的治疗方法，多尿症的治疗方法或治疗方法低血压，包括其有效成分。

32. 发明授权

US5246978A Polyol and rigid polyurethane foam 失效
标题翻译：聚氨酯和刚性聚氨酯泡沫
公开(公告)号：US5246978A
公开(公告)日：1993-09-21
申请号：US610689
申请日：1990-11-08
申请人： Satoshi Ozaki , Tsukuru Izukawa , Haruhiko Kawakami , Takayoshi Masuda , Toshio Nozawa
发明人： Satoshi Ozaki , Tsukuru Izukawa , Haruhiko Kawakami , Takayoshi Masuda , Toshio Nozawa
IPC分类号： C08G18/40 , C08G18/48 , C08G18/50 , C08G18/64 , C08G59/14 , C08G65/28 , C08L71/02
CPC分类号： C08G59/145 , C08G18/4081 , C08G18/4895 , C08G18/5021 , C08G18/6407 , C08G18/643 , C08L71/02 , C08G2101/0025 , C08G2101/005
摘要： The present invention relates to a polyol, polyurethane resin, rigid polyurethane foam, preparation process thereof and a preparation process of a rigid polyurethane foam composite. The polyol comprises an epoxy resin based polyol, which may be combined with a phenol resin based polyol component and/or an aromatic amine based polyol component. The polyurethane resin, foam and composite using the polyol as a raw material has resistance to dissolution in a hydrochlorofluorocarbon and a hydrofluorocarbon which are foaming agents having very low public environmental hazards and can be used as a thermal insulation material or a thermal insulation structure for refrigerators, freezers, insulation panels, ships and vehicles.

33. 发明授权

US08532979B2 Information processing apparatus, information processing method, and program for presenting data based upon a detection of a photographic subject 有权
标题翻译：信息处理装置，信息处理方法和用于基于拍摄对象的检测呈现数据的程序
公开(公告)号：US08532979B2
公开(公告)日：2013-09-10
申请号：US12869111
申请日：2010-08-26
申请人： Natsuko Sasaki , Satoshi Ozaki , Shingo Tsurumi
发明人： Natsuko Sasaki , Satoshi Ozaki , Shingo Tsurumi
IPC分类号： G06F17/27 , G06F17/20 , G06Q30/00
CPC分类号： H04N1/00249 , G06Q30/02 , H04N1/00244 , H04N1/00251 , H04N2201/0041 , H04N2201/0089
摘要： An information processing apparatus includes a holding unit configured to hold, in advance, presentation data to be presented to a person; a detection unit configured to detect, in a captured image obtained by capturing an image of a photographic subject, the photographic subject; a reading unit configured to read presentation data associated with a detection result of the photographic subject from among items of presentation data held in advance; and an output unit configured to output the read presentation data.
摘要翻译：一种信息处理设备，包括：保持单元，被配置为预先保存要呈现给人的呈现数据; 检测单元，被配置为在通过拍摄被摄体的图像获得的拍摄图像中检测所述摄影对象; 读取单元，被配置为从预先保存的呈现数据的项目中读取与所述摄影对象的检测结果相关联的呈现数据; 以及输出单元，被配置为输出读取的呈现数据。

34. 发明申请

US20070015792A1 N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives 有权
标题翻译： N-二羟基烷基取代的2-氧代 - 咪唑衍生物
公开(公告)号：US20070015792A1
公开(公告)日：2007-01-18
申请号：US11484203
申请日：2006-07-11
申请人： Masaya Hashimoto , Yoshikazu Iwasawa , Hiroshi Kawamoto , Hisashi Ohta , Satoshi Ozaki , Takeshi Sagara , Hiroki Sakoh , Atsushi Satoh
发明人： Masaya Hashimoto , Yoshikazu Iwasawa , Hiroshi Kawamoto , Hisashi Ohta , Satoshi Ozaki , Takeshi Sagara , Hiroki Sakoh , Atsushi Satoh
IPC分类号： A61K31/454 , C07D403/04
CPC分类号： C07D403/04
摘要： The invention provides the compounds represented by the formula (I) in which, R stands for a dihydroxy-substituted C1-C6 alkyl group, and Cy stands for an optionally substituted C6-C10 bi- or tri-cyclic aliphatic carbocyclic group. These compounds act as nociceptin receptor antagonist, and are useful, for example, as relievers against tolerance to narcotic analgesic, dependence on narcotic analgesic or addiction; analgesic enhancers; antiobestic or appetite suppressors; treating or prophylactic agents for cognitive impairment and dementia/amnesia; agents for treating developmental cognitive abnormality; remedy for schizophrenia; agents for treating neurodegenerative diseases; anti-depressant or treating agents for affective disorder; treating or prophylactic agents for diabetes insipidus; treating or prophylactic agents for polyuria; and remedy for hypotension and the like.
摘要翻译：本发明提供由式（I）表示的化合物，其中R代表二羟基取代的C 1 -C 6烷基，Cy代表任选地取代的C 6 -C 10 - 二环或三环脂族碳环基团。这些化合物作为伤害感受肽受体拮抗剂起作用，例如可用作对麻醉止痛药的耐受性，对麻醉性镇痛药或成瘾的依赖; 镇痛增强剂; 抗生素或食欲抑制剂; 认知障碍和痴呆/遗忘症的治疗或预防剂; 治疗发育性认知异常的药剂; 精神分裂症补救措施治疗神经变性疾病的药剂; 用于情感障碍的抗抑郁药或治疗剂; 尿崩症的治疗或预防剂; 多尿症的治疗或预防剂; 并补救低血压等。

35. 发明申请

US20060115858A1 Trace amine 1 receptor of the African green monkey 失效
标题翻译：非洲绿猴的痕量胺1受体
公开(公告)号：US20060115858A1
公开(公告)日：2006-06-01
申请号：US11291686
申请日：2005-12-01
申请人： Mark Massari , Herve Schaffhauser , Satoshi Ozaki
发明人： Mark Massari , Herve Schaffhauser , Satoshi Ozaki
IPC分类号： G01N33/53 , C07H21/04 , C12P21/06 , C12N5/06 , C07K14/705 , C12Q1/48
CPC分类号： C07K14/705 , C07K14/70571 , G01N33/94 , G01N2333/70571 , G01N2800/30
摘要： A trace amine receptor 1 has been isolated from the genome of Cercopithecus aethiops (African green monkey). Described is the amino acid sequence of the receptor, the nucleic acid encoding the receptor, and methods for using the receptor to identify analytes that are agonists or antagonists of the receptor.
摘要翻译：已经从Cercopithecus aethiops（非洲绿猴）的基因组中分离出微量的胺受体1。描述了受体的氨基酸序列，编码受体的核酸，以及使用受体来鉴定作为受体的激动剂或拮抗剂的分析物的方法。

36. 发明授权

US06721811B1 Message processing scheme for realizing unified handling and management of messages using a portable message processing device 有权
公开(公告)号：US06721811B1
公开(公告)日：2004-04-13
申请号：US09704606
申请日：2000-11-03
申请人： Satoshi Ozaki , Atsushi Inoue
发明人： Satoshi Ozaki , Atsushi Inoue
IPC分类号： G06F1312
CPC分类号： H04L51/00
摘要： A message processing scheme capable of realizing both a portability and a unified way of handling and managing e-mails of a given user is disclosed. The collective message processing and the unified message accesses are realized by storing and managing messages from a plurality of message delivery servers in the message processing device that is unique to the user. All mails destined to the user are collected at the message processing device regardless of a current location of the user, so that the user only needs to view mails on this message processing device.

37. 发明申请

US20090025095A1 Method for Evaluating Compound Using Barlp and Substance for Regulating Eating and Body Weight 审中-公开
标题翻译：使用Barlp和物质评价化合物调节饮食和体重的方法
公开(公告)号：US20090025095A1
公开(公告)日：2009-01-22
申请号：US11918099
申请日：2006-04-25
申请人： Hirohide Nambu , Satoshi Ozaki , Takeshi Tanaka , Hisashi Ohta
发明人： Hirohide Nambu , Satoshi Ozaki , Takeshi Tanaka , Hisashi Ohta
IPC分类号： G01N33/53 , G01N33/00 , C07K16/00 , C07H21/04 , C07H21/02 , C07K14/00 , C07K2/00
CPC分类号： G01N33/74 , C12Q1/6883 , C12Q2600/136 , C12Q2600/158 , G01N2333/72 , G01N2500/10 , G01N2800/303
摘要： It is intended to provide a method for evaluating a compound which regulates eating or body weight characterized by comprising the steps of introducing a BARLP gene and preparing a cell expressing BARLP; bringing a test compound into contact with the cell; and detecting a specific binding of the test compound to the BARLP and a method for evaluating a compound further comprising the step of evaluating a test compound using a nonhuman genetically-engineered animal in which the BARLP gene is inactivated. According to this invention, knowledge about a relationship between BARLP and biological functions is obtained and a method for evaluating a compound targeting BARLP and a BARLP ligand obtained by the evaluation can be provided.
摘要翻译：旨在提供一种评估调节进食或体重的化合物的方法，其特征在于包括引入BARLP基因并制备表达BARLP的细胞的步骤; 使测试化合物与细胞接触; 以及检测所述测试化合物与所述BARLP的特异性结合，以及评价化合物的方法，其还包括使用其中所述BARLP基因失活的非人基因工程动物评估测试化合物的步骤。根据本发明，可以获得关于BARLP与生物功能之间的关系的知识，并且可以提供通过评价获得的靶向BARLP和BARLP配体的化合物的评价方法。

38. 发明申请

US20080206786A1 Trace amine receptor 1 of the african green monkey 审中-公开
标题翻译：非洲绿猴的痕量胺受体1
公开(公告)号：US20080206786A1
公开(公告)日：2008-08-28
申请号：US12079139
申请日：2008-03-25
申请人： Mark Eben Massari , Herve Schaffhauser , Satoshi Ozaki
发明人： Mark Eben Massari , Herve Schaffhauser , Satoshi Ozaki
IPC分类号： G01N33/53 , C07H21/04 , C12N15/63 , C12P21/00 , C12N5/06
CPC分类号： C07K14/705 , C07K14/70571 , G01N33/94 , G01N2333/70571 , G01N2800/30
摘要： A trace amine receptor 1 has been isolated from the genome of Cercopithecus aethiops (African green monkey). Described is the amino acid sequence of the receptor, the nucleic acid encoding the receptor, and methods for using the receptor to identify analytes that are agonists or antagonists of the receptor.
摘要翻译：已经从Cercopithecus aethiops（非洲绿猴）的基因组中分离出微量的胺受体1。描述了受体的氨基酸序列，编码受体的核酸，以及使用受体来鉴定作为受体的激动剂或拮抗剂的分析物的方法。

39. 发明授权

US07368541B2 Trace amine receptor 1 of the African green monkey 失效
标题翻译：非洲绿猴的痕量胺受体1
公开(公告)号：US07368541B2
公开(公告)日：2008-05-06
申请号：US11291686
申请日：2005-12-01
申请人： Mark Eben Massari , Herve Schaffhauser , Satoshi Ozaki
发明人： Mark Eben Massari , Herve Schaffhauser , Satoshi Ozaki
IPC分类号： C07K14/705 , C12N15/12
CPC分类号： C07K14/705 , C07K14/70571 , G01N33/94 , G01N2333/70571 , G01N2800/30
摘要： A trace amine receptor 1 has been isolated from the genome of Cercopithecus aethiops (African green monkey). Described is the amino acid sequence of the receptor, the nucleic acid encoding the receptor, and methods for using the receptor to identify analytes that are agonists or antagonists of the receptor.
摘要翻译：已经从Cercopithecus aethiops（非洲绿猴）的基因组中分离出微量的胺受体1。描述了受体的氨基酸序列，编码受体的核酸，以及使用受体来鉴定作为受体的激动剂或拮抗剂的分析物的方法。

40. 发明申请

US20070275379A1 Simian Orl1 Gene and Method of Assessing Compound 审中-公开
标题翻译：猿猴Orl1基因及其鉴定方法
公开(公告)号：US20070275379A1
公开(公告)日：2007-11-29
申请号：US10577827
申请日：2004-11-08
申请人： Kazumi Koga , Satoshi Ozaki , Daisuke Ichikawa , Hirohide Nambu , Tomoko Azuma , Naoko Sakai , Hiroko Kawagoe , Hisashi Ohta
发明人： Kazumi Koga , Satoshi Ozaki , Daisuke Ichikawa , Hirohide Nambu , Tomoko Azuma , Naoko Sakai , Hiroko Kawagoe , Hisashi Ohta
IPC分类号： C12Q1/68 , C07H21/02 , C07K14/705 , C12N5/06
CPC分类号： C07K14/705
摘要： A nucleic acid having a base sequence of SEQ ID NO. 1; a protein having an amino acid sequence of SEQ ID NO. 2; a recombinant vector comprising a gene constituted of the above nucleic acid; and a transformant cell comprising the recombinant vector. By the use of these, it is feasible to provide ORL1 gene of non-human primates, etc. and to perform assessment, screening, etc. of compounds acting on the ORL1.
摘要翻译：具有SEQ ID NO：1的碱基序列的核酸。 1; 具有SEQ ID NO：1的氨基酸序列的蛋白质。 2; 包含由上述核酸构成的基因的重组载体; 和包含重组载体的转化体细胞。通过使用这些，可以提供非人灵长类动物的ORL1基因等，并对作用于ORL1的化合物进行评估，筛选等。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式