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31. 发明授权

US07745571B2 Peptide inhibitors of IASPP 失效
标题翻译： IASPP肽抑制剂
公开(公告)号：US07745571B2
公开(公告)日：2010-06-29
申请号：US12043058
申请日：2008-03-05
申请人： Xin Lu , Patricia Kuwabara , David Selwood
发明人： Xin Lu , Patricia Kuwabara , David Selwood
IPC分类号： A61K38/00
CPC分类号： A61K38/1709 , A61K38/193 , A61K38/50 , C07K14/4747 , A61K2300/00
摘要： The invention relates to a polypeptide or part thereof which inhibits the apoptotic activity of the tumor suppressor protein p53, and includes screening methods to identify agents which interfere with the activity of the polypeptide.
摘要翻译：本发明涉及抑制肿瘤抑制蛋白p53的凋亡活性的多肽或其部分，并且包括鉴定干扰多肽活性的试剂的筛选方法。

32. 发明申请

US20100145894A1 GENOMIC CLASSIFICATION OF COLORECTAL CANCER BASED ON PATTERNS OF GENE COPY NUMBER ALTERATIONS 失效
标题翻译：基于遗传复制序列变异图案的基因组分类
公开(公告)号：US20100145894A1
公开(公告)日：2010-06-10
申请号：US12607082
申请日：2009-10-28
申请人： Dimitri Semizarov , Xin Lu , Ke Zhang , Rick R. Lesniewski
发明人： Dimitri Semizarov , Xin Lu , Ke Zhang , Rick R. Lesniewski
IPC分类号： G06F15/18 , G06N5/02 , G06F17/30
CPC分类号： G06F19/34 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/156 , G06F19/12 , G06F19/18 , G06F19/24 , G06F19/28
摘要： The invention is directed to methods and kits that allow for classification of colorectal cancer cells according to genomic profiles, and methods of diagnosing, predicting clinical outcomes, and stratifying patient populations for clinical testing and treatment using the same.
摘要翻译：本发明涉及允许根据基因组谱分类结肠直肠癌细胞的方法和试剂盒，以及诊断，预测临床结果的方法，以及使用其进行临床测试和治疗的患者人群分层。

33. 发明申请

US20080220997A1 Solid Stick Compositions Comprising Thermosetting Plastic 失效
标题翻译：固体棒组合物，包括热固性塑料
公开(公告)号：US20080220997A1
公开(公告)日：2008-09-11
申请号：US11884252
申请日：2006-02-14
申请人： Don Eadie , Xin Lu , John Cotter
发明人： Don Eadie , Xin Lu , John Cotter
IPC分类号： C10M169/00
CPC分类号： C10M103/00 , C10M103/02 , C10M103/06 , C10M125/00 , C10M141/02 , C10M169/04 , C10M2201/041 , C10M2201/0413 , C10M2201/066 , C10M2201/0663 , C10M2207/126 , C10M2207/282 , C10M2207/285 , C10M2209/102 , C10N2210/02 , C10N2210/03 , C10N2210/04 , C10N2210/05 , C10N2230/06 , C10N2240/00 , C10N2250/08 , C10N2250/10 , C10N2250/18 , F16C33/102
摘要： The present invention provides a modified solid stick composition comprising a thermosetting plasticizer, a resin, a lubricant, a friction modifier, or a combination thereof. The solid stick compositions may be used for application between two metal surfaces in sliding and rolling-sliding contact such as steel wheel-rail systems including mass transit and freight systems. A method of reducing energy consumption, or controlling friction between a metal surface and a second metal surface by applying the solid stick composition to one or more than one of the metal surfaces, is also provided.
摘要翻译：本发明提供一种包含热固性增塑剂，树脂，润滑剂，摩擦改进剂或其组合的改性固体粘合剂组合物。固体棒组合物可用于滑动和滚动滑动接触中的两个金属表面之间的应用，例如包括公共交通和货运系统的钢轮轨道系统。还提供了一种通过将固体棒组合物施加到一个或多于一个金属表面来降低能量消耗或控制金属表面和第二金属表面之间的摩擦的方法。

34. 发明申请

US20070225240A1 Screening Assay and Treatment 审中-公开
标题翻译：筛选测定和治疗
公开(公告)号：US20070225240A1
公开(公告)日：2007-09-27
申请号：US10581569
申请日：2004-09-13
申请人： Xin Lu , Nadia Godin-Heymann
发明人： Xin Lu , Nadia Godin-Heymann
IPC分类号： A61K31/7088 , A01K67/027 , C07K16/32 , C12N15/63 , C12N5/16 , G01N33/574
CPC分类号： A61K38/1709 , A01K2267/0331 , G01N33/5748 , G01N2500/00 , G01N2500/02 , G01N2510/00
摘要： The invention relates to screening assays for the identification of agents which modulate the activity of polypeptides which affect the apoptotic activity of the tumour suppressor protein p53 and including gene therapy vectors comprising p53 and antibodies that bind phosphorylated epitopes.
摘要翻译：本发明涉及用于鉴定调节影响肿瘤抑制蛋白p53的凋亡活性的多肽的活性的试剂的筛选测定法，并且包括包含p53的基因治疗载体和结合磷酸化表位的抗体。

35. 发明申请

US20060100143A1 Polypeptide 审中-公开
标题翻译：多肽
公开(公告)号：US20060100143A1
公开(公告)日：2006-05-11
申请号：US10522043
申请日：2003-10-03
申请人： Xin Lu , Patricia Kuwabara , David Selwood
发明人： Xin Lu , Patricia Kuwabara , David Selwood
IPC分类号： A61K39/00 , C07K14/82 , C12Q1/68 , C07H21/04 , C12P21/06
CPC分类号： A61K38/1709 , A61K38/193 , A61K38/50 , C07K14/4747 , A61K2300/00
摘要： The invention relates to a polypeptide, or part thereof, which inhibits the apoptotic activity of the tumour suppressor protein p53 and including screening methods to identify agents which interfere with the activity of said polypeptide.
摘要翻译：本发明涉及抑制肿瘤抑制蛋白p53的凋亡活性的多肽或其部分，并且包括筛选方法来鉴定干扰所述多肽的活性的试剂。

36. 发明申请

US20060098127A1 Display device with a detachable housing 失效
标题翻译：具有可拆卸外壳的显示装置
公开(公告)号：US20060098127A1
公开(公告)日：2006-05-11
申请号：US11267066
申请日：2005-11-04
申请人： Kuan-Hong Hsieh , Xin Lu , Xiao-Guang Li , Zhong-Wu Tian , Hsueh-Tsung Lu
发明人： Kuan-Hong Hsieh , Xin Lu , Xiao-Guang Li , Zhong-Wu Tian , Hsueh-Tsung Lu
IPC分类号： H04N5/50 , H04N5/64
CPC分类号： H04N5/44504 , H04N21/414 , H04N21/4312 , H04N21/485
摘要： A display device includes a detachable housing, a main body, and an interface unit. The interface unit electrically connects the detachable housing with the main body. The detachable housing includes an OSD unit for storing a plurality of OSD data; a command input unit for generating and sending signals in response to operations of a user; a processing unit for identifying operations of the user, and, if required by the operations, performing predetermined function to obtain OSD data, generating a corresponding control signal, and transmitting the OSD data and the control signal to the main body through the interface unit. The main body displays an OSD menu corresponding to the OSD data and adjusts the parameters of the display device, corresponding to the control signals.
摘要翻译：显示装置包括可拆卸的外壳，主体和接口单元。接口单元将可拆卸外壳与主体电连接。可拆卸外壳包括用于存储多个OSD数据的OSD单元; 命令输入单元，用于响应于用户的操作产生和发送信号; 用于识别用户的操作的处理单元，以及如果操作需要，执行预定功能以获得OSD数据，生成相应的控制信号，以及通过接口单元将OSD数据和控制信号发送到主体。主体显示与OSD数据对应的OSD菜单，并调整对应于控制信号的显示装置的参数。

37. 发明申请

US20060015282A1 System and method for testing a display device 审中-公开
标题翻译：用于测试显示设备的系统和方法
公开(公告)号：US20060015282A1
公开(公告)日：2006-01-19
申请号：US11175770
申请日：2005-07-06
申请人： Kuan-Hong Hsieh , Zhong-Wu Tian , Xin Lu , Jun-Jian Li
发明人： Kuan-Hong Hsieh , Zhong-Wu Tian , Xin Lu , Jun-Jian Li
IPC分类号： G06F19/00
CPC分类号： G09G3/006
摘要： A display device testing system includes a video signal outputting apparatus (10), a remote controller (20), a back board (30) and a display device (40). The video outputting apparatus outputs video signals which contain one or more testing samples provided for testing the display device to the display device. The remote controller generates control signals to control the display device to display the testing samples. The back board includes an interface. The interface receives the control signals from the controller, combines the control signals with the video signals into mixed signals, and transmits the mixed signals to the display device to obtain a test result. The test result is sent back to the remote controller via the back board for evaluating the performances of the display device. A related method is also disclosed.
摘要翻译：显示设备测试系统包括视频信号输出设备（10），遥控器（20），后板（30）和显示设备（40）。视频输出装置向显示装置输出包含提供用于测试显示装置的一个或多个测试样本的视频信号。遥控器产生控制信号以控制显示设备显示测试样品。背板包括一个接口。该接口接收来自控制器的控制信号，将控制信号与视频信号组合成混合信号，并将混合信号发送到显示装置以获得测试结果。测试结果通过背板发送回遥控器，用于评估显示设备的性能。还公开了相关方法。

38. 发明申请

US20050149524A1 Automated system and method for generating reasons that a court case is cited 有权
公开(公告)号：US20050149524A1
公开(公告)日：2005-07-07
申请号：US11056200
申请日：2005-02-14
申请人： Timothy Humphrey , Xin Lu , Afsar Parhizgar , Salahuddin Ahmed , James Wiltshire , John Morelock , Joseph Harmon , Spiro Collias , Paul Zhang
发明人： Timothy Humphrey , Xin Lu , Afsar Parhizgar , Salahuddin Ahmed , James Wiltshire , John Morelock , Joseph Harmon , Spiro Collias , Paul Zhang
IPC分类号： G06F17/27 , G06F17/30 , G06F7/00
CPC分类号： G06F17/30613 , G06F17/27 , G06F17/2755 , G06F17/30728 , Y10S707/917 , Y10S707/942 , Y10S707/99932 , Y10S707/99933 , Y10S707/99934 , Y10S707/99935 , Y10S707/99937
摘要： A computer-automated system and method identify text in a first “citing” court case, near a “citing instance” (in which a second “cited” court case is cited), that indicates the reason(s) for citing (RFC). The automated method of designating text, taken from a set of citing documents, as reasons for citing (RFC) that are associated with respective citing instances of a cited document, has steps including: obtaining contexts of the citing instances in the respective citing documents (each context including text that includes the citing instance and text that is near the citing instance), analyzing the content of the contexts, and selecting (from the citing instances' context) text that constitutes the RFC, based on the analyzed content of the contexts. A related computer-automated system and method selects content words that are highly related to the reasons a particular document is cited, and gives them weights that indicate their relative relevance. Another related computer-automated system and method forms lists of morphological forms of words. Still another related computer-automated system and method scores sentences to show their relevance to the reasons a document is cited. Also, another related computer-automated system and method generates lists of content words. In a preferred embodiment, the systems and methods are applied to legal (especially case law) documents and legal (especially case law) citations.

39. 发明申请

US20050123977A1 Assay and treatment 审中-公开
标题翻译：测定和治疗
公开(公告)号：US20050123977A1
公开(公告)日：2005-06-09
申请号：US11004749
申请日：2004-12-03
申请人： Xin Lu
发明人： Xin Lu
IPC分类号： A61K38/16 , C07K14/47 , C07K16/00 , C12Q1/68 , G01N33/574 , G01N33/68 , C07H21/04 , C07K16/40 , C12N9/64
CPC分类号： C07K14/4746 , C12Q1/6886 , C12Q2600/136 , G01N33/5748 , G01N33/6875 , G01N2500/02 , G01N2510/00
摘要： We describe screening methods for agents which modulate the interaction of p53 activator/inhibitor binding proteins with polymorphic p53 polypeptide variants, cells expressing combinations of said activator/inhibitor proteins and p53 variants; diagnostic assays to determine the genotype of an individual with respect to said p53 polymorphism; and therapeutic compositions for use in the treatment of conditions which would benefit from a stimulation of apoptosis.
摘要翻译：我们描述调节p53激活物/抑制剂结合蛋白与多态性p53多肽变体，表达所述激活物/抑制蛋白和p53变体组合的细胞的相互作用的试剂的筛选方法; 用于确定个体相对于所述p53多态性的基因型的诊断测定; 以及用于治疗可受益于细胞凋亡刺激的病症的治疗组合物。

40. 发明授权

US09460120B2 Travel route planning using geo-tagged photographs 有权
标题翻译：使用地理标记照片的旅行路线规划
公开(公告)号：US09460120B2
公开(公告)日：2016-10-04
申请号：US12896635
申请日：2010-10-01
申请人： Changhu Wang , Jiang-Ming Yang , Lei Zhang , Xin Lu
发明人： Changhu Wang , Jiang-Ming Yang , Lei Zhang , Xin Lu
IPC分类号： G01C21/00 , G06F17/30 , G01C21/34 , G01C21/36
CPC分类号： G06F17/30265 , G01C21/343 , G01C21/3476 , G01C21/3484 , G01C21/3647 , G06F17/30056
摘要： Systems, methods, and devices are described for providing customized trip plans. Based on information provided by a user, geo-tagged photographs, and/or travelogues, one or more travel destinations are identified. Travel paths typically taken by tourists within each of the travel destinations and stay times within those travel destinations may be determined. A customized trip plan including a travel route plan among the one or more travel destinations and recommended internal paths within each travel destination are provided to the user. A revised customized trip plan may also be provided in response to changes made to information associated with the user.
摘要翻译：描述了系统，方法和设备，以提供定制的旅行计划。根据用户提供的信息，地理标记的照片和/或旅行记录，识别一个或多个旅行目的地。每个旅游目的地内的游客通常采用的旅行路线，以及旅行目的地内的停留时间。向用户提供包括一个或多个旅行目的地内的旅行路线计划和每个旅行目的地内的推荐内部路径的定制行程计划。还可以响应于对与用户相关联的信息的改变来提供修改的定制旅行计划。

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