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    • 34. 发明授权
    • Methods and devices for noninvasive measurement of energy absorbers in blood
    • 用于无创测量血液中能量吸收器的方法和装置
    • US08818472B2
    • 2014-08-26
    • US12679721
    • 2008-09-29
    • Dietrich GravensteinMark RiceSamsun LampotangNikolaus GravensteinLori Deitte
    • Dietrich GravensteinMark RiceSamsun LampotangNikolaus GravensteinLori Deitte
    • A61B5/00
    • A61B8/06A61B5/14552
    • Various embodiments of the present invention include devices for use in determining the concentration of a tissue energy absorber (e.g., hemoglobin) in an individual's blood. In particular embodiments, the device includes a photometric device (e.g., a pulse oximeter) and an imaging device (e.g., an ultrasound imaging device or other suitable imaging device), and the device is adapted for: (A) using the photometric device to measure a change in mass of the tissue energy absorber within a particular volume of the individual's blood between a first point in time and a second point in time, the particular volume of blood being blood within a particular portion of at least one vascular structure, the vascular structure comprising at least one of the individual's vessels (e.g., at least one of the individual's arteries); (B) using an ultrasound imaging device to measure a change in interior volume, between the first point in time and the second point in time, of the particular portion of the vascular structure; and (C) using both the measured change in the mass of the tissue energy absorber, and the measured change in interior volume to determine at least an approximate blood total concentration of the tissue energy absorber within the individual's blood.
    • 本发明的各种实施方案包括用于确定个体血液中的组织能量吸收剂(例如,血红蛋白)的浓度的装置。 在特定实施例中,该装置包括测光装置(例如,脉搏血氧计)和成像装置(例如,超声成像装置或其它合适的成像装置),并且该装置适于:(A)使用光度装置 测量在第一时间点和第二时间点之间的个体血液的特定体积内的组织能量吸收器的质量变化,血液的特定体积是至少一个血管结构的特定部分内的血液, 血管结构包括个体血管中的至少一个(例如,个体动脉中的至少一个); (B)使用超声成像装置来测量血管结构的特定部分的第一时间点和第二时间点之间的内部体积的变化; 和(C)使用所测量的组织能量吸收器的质量的变化和所测量的内部体积的变化来确定个体血液内的组织能量吸收器的至少近似血液总浓度。
    • 36. 发明授权
    • Apparatus and method for mask free delivery of an inspired gas mixture and gas sampling
    • 用于无气体输送吸气混合气体和气体取样的装置和方法
    • US07997271B2
    • 2011-08-16
    • US11640930
    • 2006-12-19
    • Randall S HickleSamsun Lampotang
    • Randall S HickleSamsun Lampotang
    • A61M16/00A61M15/08A62B18/08A62B18/02A62B7/00
    • A61B5/0836A61B5/097A61B5/6819A61M16/024A61M16/0666A61M16/0677A61M16/0683A61M16/0808A61M16/085A61M16/0858A61M2205/0216A61M2205/3375A61M2210/0618A61M2210/0625A61M2230/432A61M2230/437
    • This disclosure is of a mask-free device for supplying sufficient gas to a medical patient and for more accurately sampling the exhalation gas of the patient. The device includes a flexible body having lumens adapted to extend into the nares of a patient and adjacent the patient's mouth for collecting and transmitting a sampling of the patient's end tidal exhalation to a gas analyzer to analyze one or more component gases in that exhalation. The disclosure also discloses the transmittal of pressure from the nares of the patient to a pressure transducer for determining the respiratory phase of the patient and for controlling the volume of oxygen delivered to the patient. The body of the mask-free unit further includes conduits for delivering oxygen through diffuser orifices to positions adjacent the patient's nares and mouth. Finally, a controller is interconnected between the pressure transducer and the gas supply for increasing the delivery of gas during the inhalation phase of the patient's respiration and for decreasing said delivery upon the exhalation phase for the purpose of avoiding dilution of the exhalation sample.
    • 本公开是用于向医疗患者提供足够的气体并且更准确地对患者的呼出气体取样的无掩模装置。 该装置包括柔性体,其具有适于延伸到患者的鼻孔并且邻近患者嘴部的腔,用于收集和传送患者的末端潮气呼气的采样并将其发送到气体分析器以分析呼气中的一种或多种组分气体。 本公开还公开了从患者的鼻孔传递压力到压力换能器,用于确定患者的呼吸相位并控制输送给患者的氧气体积。 无面罩单元的主体还包括用于通过扩散器孔将氧输送到邻近患者的鼻孔和嘴部的位置的导管。 最后,控制器在压力传感器和气体供应之间相互连接,用于增加在患者呼吸的吸入阶段期间气体的输送,并且为了避免呼气样本的稀释,在呼气阶段减少所述输送。