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31. 发明申请

WO2008055171A3 PROCESS AND REACTOR FOR UPGRADING HEAVY HYDROCARBON OILS 审中-公开
标题翻译：升级重油石油的工艺和反应器
公开(公告)号：WO2008055171A3
公开(公告)日：2008-09-12
申请号：PCT/US2007083038
申请日：2007-10-30
申请人： CHEVRON USA INC , HE ZUNQING , LI LIN , LI LIXIONG , ZESTAR LAWRENCE P , CHINN DANIEL
发明人： HE ZUNQING , LI LIN , LI LIXIONG , ZESTAR LAWRENCE P , CHINN DANIEL
IPC分类号： C10G17/00
CPC分类号： C10G31/00
摘要： A process using supercritical water to upgrade a heavy hydrocarbon feedstock into an upgraded hydrocarbon product or syncrude with highly desirable properties (low sulfur content, low metals content, lower density (higher API) lower viscosity, lower residuum content, etc.) is described. The process does not require external supply of hydrogen nor does it use externally supplied catalysts. A reactor design to carry out the process is also described.
摘要翻译：描述了使用超临界水将重质烃原料升级成具有高度期望性质（低硫含量，低金属含量，较低密度（较高API）较低粘度，较低渣油含量等）的升级烃产物或合成原料的方法。该方法不需要外部氢气供应，也不需要使用外部供应的催化剂。还描述了进行该过程的反应器设计。

32. 发明申请

WO2008055155A2 UPGRADING HEAVY HYDROCARBON OILS 审中-公开
标题翻译：升级重油油
公开(公告)号：WO2008055155A2
公开(公告)日：2008-05-08
申请号：PCT/US2007082999
申请日：2007-10-30
申请人： CHEVRON USA INC , HE ZUNQING , CHINN DANIEL , LI LIXIONG , LI LIN
发明人： HE ZUNQING , CHINN DANIEL , LI LIXIONG , LI LIN
IPC分类号： C10G45/00 , C10G31/00
CPC分类号： C10G31/08
摘要： A process using supercritical water to upgrade a heavy hydrocarbon feedstock into an upgraded hydrocarbon product or syncrude with highly desirable properties (low sulfur content, low metals content, lower density (higher API), lower viscosity, lower residuum content, etc.) is disclosed. The process does not require external supply of hydrogen nor does it use externally supplied catalysts.
摘要翻译：公开了一种使用超临界水将重质烃原料升级成具有高度期望性质（低硫含量，低金属含量，较低密度（较高API），较低粘度，较低渣油含量等）的升级烃产物或合成原料的方法）。该方法不需要外部氢气供应，也不需要使用外部供应的催化剂。

33. 发明申请

WO2012058228A3 METHOD FOR REDUCING MERCAPTANS IN HYDROCARBONS 审中-公开
标题翻译：降低烃类中MERCAPTANS的方法
公开(公告)号：WO2012058228A3
公开(公告)日：2012-08-16
申请号：PCT/US2011057722
申请日：2011-10-25
申请人： CHEVRON USA INC , LI LIN , HE ZUNQING , ZHOU ZHEN , NG KING T , HAJDU PAUL E
发明人： LI LIN , HE ZUNQING , ZHOU ZHEN , NG KING T , HAJDU PAUL E
IPC分类号： C10G27/02 , C10G19/08 , C25B1/00
CPC分类号： C10G27/02 , C10G27/06 , C10G33/00 , C10G2300/1033 , C10G2300/202 , C10G2400/08
摘要： A method for reducing mercaptan concentration in a crude oil is disclosed. The method comprises contacting the crude with a treating solution comprising a hypochlorite solution, whereby the mercaptan sulfur is oxidized and converted to at least one sulfur oxoacid or salt thereof, yielding a treated crude oil having less than 50 ppm mercaptan sulfur and residual chloride. The treated crude oil containing residual chloride is brought in contact with a caustic solution at a molar ratio of caustic to chloride of 0.05:1 to 1:1, generating an upgraded crude oil with less than 50 ppm chloride. In one embodiment, the spent treating solution is recycled to form a regenerated hypochlorite stream for use in the treatment solution.
摘要翻译：公开了一种降低原油中硫醇浓度的方法。该方法包括使原油与包含次氯酸盐溶液的处理溶液接触，其中硫醇硫被氧化并转化成至少一种硫含氧酸或其盐，从而产生具有小于50ppm硫醇硫和残余氯的经处理的原油。使含有残余氯化物的经处理的原油与苛性碱溶液以0.05：1至1：1的苛性碱与氯化物的摩尔比接触，产生具有小于50ppm氯化物的升级原油。在一个实施方案中，废处理溶液被再循环以形成用于处理溶液中的再生次氯酸盐流。

34. 发明申请

WO2012030492A3 TREATMENT OF HYDROCARBON FEED 审中-公开
标题翻译：处理油料进料
公开(公告)号：WO2012030492A3
公开(公告)日：2012-07-05
申请号：PCT/US2011047202
申请日：2011-08-10
申请人： CHEVRON USA INC , HUSAIN SHABBIR , LI LIN , ZHOU ZHEN , KUPERMAN ALEXANDER E , HE ZUNQING , LUO HUPING
发明人： HUSAIN SHABBIR , LI LIN , ZHOU ZHEN , KUPERMAN ALEXANDER E , HE ZUNQING , LUO HUPING
IPC分类号： C10G31/00 , B01J21/06 , C07C7/00 , C10G3/00 , C10L1/02
CPC分类号： C10L1/02 , B01J21/063 , B01J23/002 , B01J23/02 , B01J23/06 , C10G3/45 , C10G3/49 , C10G29/00 , C10G29/04 , C10G2300/1014 , C10G2300/1018 , C10G2300/1033 , C10G2300/107 , C10G2300/1074 , C10G2300/1077 , C10G2300/202 , C10G2300/203 , C10G2300/4018 , C10L1/04 , Y02P30/20 , Y02P30/446
摘要： Disclosed are embodiments relating to a process for treating a hydrocarbon feedstock. In one embodiment with a biologically derived oil as the feedstock, the biologically derived oil feed is deoxygenated by contacting the feed with a metal titanate catalyst having an MTiO3 structure wherein M is a metal having a valence of 2+. In another embodiment with a high acid crude oil as the feedstock, the metal titanate catalyst is employed to reduce the total acid number of the hydrocarbon feed by contacting the feed with the metal titanate catalyst, resulting in a hydrocarbon product having a final total acid number lower than the initial total acid number of the feed. The process can be integrated into conventional refining operations in order to treat refinery feedstreams, whether it is a biofuel source, or a high acid crude.
摘要翻译：公开的是涉及用于处理烃原料的方法的实施方案。在生物衍生的油作为原料的一个实施方案中，生物衍生的油进料通过使进料与具有MTiO 3结构的金属钛酸盐催化剂接触而脱氧，其中M是具有2+价态的金属。在高酸性原油作为原料的另一个实施方案中，钛酸金属催化剂用于通过使进料与金属钛酸盐催化剂接触来降低烃进料的总酸值，得到具有最终总酸值的烃产物低于饲料的初始总酸值。该方法可以被整合到常规的精炼操作中，以便处理炼油原料流，无论是生物燃料源还是高酸原油。

35. 发明申请

WO2012057935A3 METHOD FOR REDUCING MERCAPTANS IN HYDROCARBONS 审中-公开
标题翻译：减少碳氢化合物的方法
公开(公告)号：WO2012057935A3
公开(公告)日：2012-06-14
申请号：PCT/US2011052155
申请日：2011-09-19
申请人： CHEVRON USA INC , HE ZUNQING , ZHOU ZHEN , LI LIN
发明人： HE ZUNQING , ZHOU ZHEN , LI LIN
IPC分类号： C10G27/02 , C10G27/06 , C10G31/08 , C10G33/00 , C10L1/04
CPC分类号： C10G27/02 , C10G27/06 , C10G33/00 , C10G2300/1033 , C10G2300/202 , C10G2400/08
摘要： A method for reducing mercaptan concentration in a liquid hydrocarbon, comprising: contacting a mercaptan-rich liquid hydrocarbon having a first concentration of mercaptan sulfur with a composition comprising an oxidizing agent and water wherein the molar ratio of the oxidizing agent to mercaptan sulfur in the mercaptan-rich liquid hydrocarbon is from 3:1 to 10:1; and separating the water from the liquid hydrocarbon to yield a mercaptan-depleted liquid hydrocarbon having a second concentration of mercaptan sulfur, the second concentration being less than the first concentration; wherein a major amount of mercaptan compounds in the mercaptan-rich liquid hydrocarbon are converted to at least one sulfur oxoacid or salt thereof, having the formula: [RSOx]nY wherein R is a hydrocarbyl group; x is an integer from 1 to 3; n is 1 or 2; and Y is hydrogen, an alkaline metal, or alkaline earth metal.
摘要翻译：一种用于降低液体烃中硫醇浓度的方法，包括：使具有第一浓度的硫醇硫的富硫醇液体烃与包含氧化剂和水的组合物接触，其中硫醇中的氧化剂与硫醇的摩尔比富液体烃为3：1至10：1; 并从液态烃中分离出水，得到具有第二浓度的硫醇硫的硫醇贫乏液体烃，第二浓度小于第一浓度; 其中所述富硫醇溶液中的主要量的硫醇化合物被转化成至少一种具有下式的硫代酸或其盐：其中R是烃基的[RSO x] n Y; x是1至3的整数; n为1或2; Y是氢，碱金属或碱土金属。

36. 发明申请

WO2012030443A3 BIOFUEL PRODUCTION THROUGH CATALYTIC DEOXYGENATION 审中-公开
标题翻译：催化脱氧生物柴油生产
公开(公告)号：WO2012030443A3
公开(公告)日：2012-05-18
申请号：PCT/US2011044722
申请日：2011-07-20
申请人： CHEVRON USA INC , ZHOU ZHEN , HUSAIN SHABBIR , LI LIN
发明人： ZHOU ZHEN , HUSAIN SHABBIR , LI LIN
IPC分类号： C10G31/00 , B01J21/06 , C07C7/00 , C10G3/00 , C10L1/02
CPC分类号： C10G3/48 , B01J21/063 , B01J23/002 , B01J23/06 , C10B53/02 , C10G3/45 , C10G3/49 , C10G2300/1014 , C10G2300/1018 , C10G2300/202 , C10G2300/4018 , Y02P30/20
摘要： A process useful for treating biologically derived oils in the production of biofuels is described. A biologically derived oil feed is deoxygenated by contacting the feed with a metal titanate catalyst. The process does not require the addition of hydrogen.
摘要翻译：描述了用于在生物燃料生产中处理生物衍生油的方法。通过使进料与金属钛酸盐催化剂接触使生物衍生的油进料脱氧。该过程不需要添加氢气。

37. 发明申请

WO2008042762A2 SINGLE NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH CARDIOVASCULAR DISEASE 审中-公开
标题翻译：单核细胞多态性与心血管疾病相关
公开(公告)号：WO2008042762A2
公开(公告)日：2008-04-10
申请号：PCT/US2007079862
申请日：2007-09-28
申请人： CLEVELAND CLINIC FOUNDATION , WANG QINY , TOPOL ERIC J , SHEN GONG-QING , LI LIN , RAO SHAOQI
发明人： WANG QINY , TOPOL ERIC J , SHEN GONG-QING , LI LIN , RAO SHAOQI
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： A method is provided for identifying a subject who has an increased risk for developing a cardiovascular disease. The method can include detecting an alteration in a portion of a LRP8 gene. The alternation can be located in at least one of exon 9, exon 17, exon 19, or intron 6 of the LRP8 gene. The presence of the alteration can be correlated with an increased risk for developing the cardiovascular disease.
摘要翻译：提供了一种用于鉴定患有心血管疾病发展风险增加的受试者的方法。该方法可以包括检测LRP8基因的一部分的改变。交替可以位于LRP8基因的外显子9，外显子17，外显子19或内含子6中的至少一个。改变的存在可以与发展心血管疾病的风险增加相关。

38. 发明申请

WO9921845A2 4-AMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF CYCLIN-DEPENDENT KINASES 审中-公开
标题翻译： 4-氨基噻唑衍生物，它们的制备及其作为依赖于细胞周期蛋白依赖性激酶的抑制剂的用途
公开(公告)号：WO9921845A2
公开(公告)日：1999-05-06
申请号：PCT/US9822809
申请日：1998-10-27
申请人： AGOURON PHARMA , CHONG WESLEY K M , CHU SHAO SONG , DUVADIE ROHIT R , LI LIN , XIAO WEI , YANG YI
发明人： CHONG WESLEY K M , CHU SHAO SONG , DUVADIE ROHIT R , LI LIN , XIAO WEI , YANG YI
IPC分类号： C07D277/20 , A61K31/426 , A61K31/427 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/551 , A61P35/00 , A61P43/00 , C07D213/00 , C07D235/00 , C07D277/42 , C07D277/56 , C07D333/00 , C07D417/06 , C07D417/12 , C07D417/14 , C07D521/00 , A61K31/425 , A61K31/44 , A61K31/47 , A61K31/50
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/42 , C07D417/06 , C07D417/12 , C07D417/14
摘要： This invention is directed to aminothiazole compounds of formula (I) wherein R is a substituted or unsubstituted group selected from: C1-6-alkyl; C1-6-alkenyl; C1-6-alkynyl; C1-6-alkoxyl; C1-6-alcohol; carbocyclic or heterocyclic, monocyclic or fused or non-fused polycyclic, cycloalkyl; carbocyclic or heterocyclic, monocyclic or fused or non-fused polycyclic, aryl; carbonyl; ether; (C1-6-alkyl)-carbonyl; (C1-6-alkyl)-aryl; (C1-6-alkyl)-cycloalkyl; (C1-6-alkyl)-(C1-6-alkoxyl); aryl-(C1-6-alkoxyl); thioether; thiol; and sulfonyl; wherein when R is substituted, each substituent independently is a halogen; haloalkyl; C1-6-alkyl; C1-6-alkenyl; C1-6-alkynyl; hydroxyl; C1-6-alkoxyl; amino; nitro; thiol; thioether; imine; cyano; amido; phosphonato; phosphine; carboxyl; thiocarbonyl; sulfonyl; sulfonamide; ketone; aldehyde; ester; oxygen; carbocyclic or heterocyclic, monocyclic or fused or non-fused polycyclic, cycloalkyl; or carbocyclic or heterocyclic, monocyclic or fused or non-fused polycyclic, aryl; and R is a carbocyclic or heterocyclic, monocyclic or fused or non-fused polycyclic, ring structure having a substituent at the position adjacent to the point of attachment, which ring structure is optionally further substituted, where each substituent of R independently is a halogen; haloalkyl; C1-6-alkyl; C1-6-alkenyl; C1-6-alkynyl; hydroxyl; C1-6-alkoxyl; amino; nitro; thiol; thioether; imine; cyano; amido; phosphonato; phosphine; carboxyl; thiocarbonyl; sulfonyl; sulfonamide; ketone; aldehyde; ester; oxygen; carbocyclic or heterocyclic, monocyclic or fused or non-fused polycyclic, cycloalkyl; or carbocyclic or heterocyclic, monocyclic or fused or non-fused polycyclic, aryl; or a pharmaceutically acceptable salt of a compound of formula (I), or a prodrug or pharmaceutically active metabolite of a compound of formula (I) or pharmaceutically acceptable salt thereof, for inhibiting cyclin-dependent kinases (CDKs), such as CDK1, CDK2, CDK4, and CDK6. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds and to methods of treating malignancies and other disorders by administering effective amounts of such compounds.
摘要翻译：本发明涉及式（I）的氨基噻唑化合物，其中R 1是取代或未取代的选自以下的基团：C 1-6 - 烷基; C 1-6 - 链烯基; C 1-6 - 炔基; C 1-6 - 烷氧基取代; C 1-6 - 醇; 碳环或杂环，单环或稠合或非稠合多环，环烷基; 碳环或杂环，单环或稠合或非稠合多环，芳基; 羰; 醚; （C 1-6 - 烷基）羰基; （C 1-6 - 烷基） - 芳基; （C 1-6 - 烷基） - 环烷基; （C 1-6 - 烷基） - （C 1-6 - 烷氧基）; 芳基 - （C 1-6 - 烷氧基）; 硫醚; 巯基; 和磺酰基; 其中当R 1被取代时，每个取代基独立地为卤素; 卤代; C 1-6 - 烷基; C 1-6 - 链烯基; C 1-6 - 炔基; 羟; C 1-6 - 烷氧基取代; 氨基; 硝基; 巯基; 硫醚; 亚胺; 氰基; 酰胺基; 膦酸; 膦; 羧基; 硫代羰基; 磺酰基; 磺胺; 酮; 醛; 酯; 氧; 碳环或杂环，单环或稠合或非稠合多环，环烷基; 或碳环或杂环，单环或稠合或非稠合的多环芳基; 并且R 2是碳环或杂环的单环或稠合或非稠合的多环环结构，其在与连接点相邻的位置上具有取代基，该环结构任选进一步被取代，其中R 2的每个取代基 >独立地为卤素; 卤代; C 1-6 - 烷基; C 1-6 - 链烯基; C 1-6 - 炔基; 羟; C 1-6 - 烷氧基取代; 氨基; 硝基; 巯基; 硫醚; 亚胺; 氰基; 酰胺基; 膦酸; 膦; 羧基; 硫代羰基; 磺酰基; 磺胺; 酮; 醛; 酯; 氧; 碳环或杂环，单环或稠合或非稠合多环，环烷基; 或碳环或杂环，单环或稠合或非稠合的多环芳基; 或式（I）化合物的药学上可接受的盐，或式（I）化合物或其药学上可接受的盐的前药或药学活性代谢物用于抑制细胞周期蛋白依赖性激酶（CDK）如CDK1，CDK2 ，CDK4和CDK6。本发明还涉及含有这些化合物的药物组合物的治疗或预防用途以及通过施用有效量的这些化合物治疗恶性肿瘤和其他病症的方法。

39. 发明申请

US20130063986A1 CONTROL CIRCUIT FOR CONTROLLING THE MAXIMUM OUTPUT CURRENT OF POWER CONVERTER AND METHOD THEREOF 有权
标题翻译：用于控制功率转换器的最大输出电流的控制电路及其方法
公开(公告)号：US20130063986A1
公开(公告)日：2013-03-14
申请号：US13611091
申请日：2012-09-12
申请人： TA-YUNG YANG , LI LIN , YUE-HONG TANG , JUNG-SHENG CHEN
发明人： TA-YUNG YANG , LI LIN , YUE-HONG TANG , JUNG-SHENG CHEN
IPC分类号： H02M3/335
CPC分类号： H02M3/33507 , H02M2001/0003
摘要： A control circuit of the power converter according to the present invention comprises a feedback circuit, an output circuit and an adaptive clamping circuit. The feedback circuit generates a feedback signal in accordance with an output of the power converter. The output circuit generates a switching signal in accordance with the feedback signal for regulating the output of the power converter. The adaptive clamping circuit limits the level of the feedback signal under a first level for a first load condition. The feedback circuit determines a slew rate of the feedback signal for increasing the level of the feedback signal from the first level to a second level. The adaptive clamping circuit is disabled and the level of the feedback signal can be increased to the second level for a second load condition.
摘要翻译：根据本发明的功率转换器的控制电路包括反馈电路，输出电路和自适应钳位电路。反馈电路根据功率转换器的输出产生反馈信号。输出电路根据用于调节功率转换器的输出的反馈信号产生开关信号。自适应钳位电路在第一负载条件下将反馈信号的电平限制在第一电平。反馈电路确定用于将反馈信号的电平从第一电平增加到第二电平的反馈信号的转换速率。自适应钳位电路被禁用，并且反馈信号的电平可以在第二负载条件下增加到第二电平。

40. 发明申请

US20120081039A1 METHOD AND APPARATUS FOR A LED DRIVER WITH HIGH POWER FACTOR 有权
标题翻译：用于具有高功率因数的LED驱动器的方法和装置
公开(公告)号：US20120081039A1
公开(公告)日：2012-04-05
申请号：US13073095
申请日：2011-03-28
申请人： TA-YUNG YANG , LI LIN , CHIH-HSIEN HSIEH , CHUH-CHING LI , CHI-YIN LO , KUO-HSIEM HUANG
发明人： TA-YUNG YANG , LI LIN , CHIH-HSIEN HSIEH , CHUH-CHING LI , CHI-YIN LO , KUO-HSIEM HUANG
IPC分类号： H05B37/02
CPC分类号： H05B33/0815
摘要： A control circuit of a LED driver according to the present invention comprises an output circuit, an input circuit and an input-voltage detection circuit. The output circuit generates a switching signal to produce an output current for driving at least one LED in response to a feedback signal. The switching signal is coupled to switch a transformer. The input circuit samples an input signal for generating the feedback signal. The input signal is correlated to the output current of the LED driver. The input-voltage detection circuit generates an input-voltage signal in response to an input voltage of the LED driver. The input circuit will not sample the input signal when the input-voltage signal is lower than a threshold. The control circuit can eliminate the need of the input capacitor for improving the reliability of the LED driver.
摘要翻译：根据本发明的LED驱动器的控制电路包括输出电路，输入电路和输入电压检测电路。输出电路产生开关信号以产生用于响应于反馈信号驱动至少一个LED的输出电流。开关信号被耦合以切换变压器。输入电路对输入信号进行采样以产生反馈信号。输入信号与LED驱动器的输出电流相关。输入电压检测电路根据LED驱动器的输入电压产生输入电压信号。当输入电压信号低于阈值时，输入电路不会对输入信号进行采样。控制电路可以消除输入电容器的需要，提高LED驱动器的可靠性。

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