专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明申请

US20060270714A1 Novel n-substituted 2-aminopyridine derivatives 审中-公开
标题翻译：新的n-取代的2-氨基吡啶衍生物
公开(公告)号：US20060270714A1
公开(公告)日：2006-11-30
申请号：US10551495
申请日：2004-03-30
申请人： David Cheshire , Stephen Connolly , Timothy Luker , Jeffrey Stonehouse
发明人： David Cheshire , Stephen Connolly , Timothy Luker , Jeffrey Stonehouse
IPC分类号： C07D213/78 , A61K31/44
CPC分类号： C07D213/74
摘要： There are provided novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R17, L1, L2, L3 and Q are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease and pain.
摘要翻译：提供了新的式（I）化合物，其中R 1，R 2，R 3，R 4， R 5，R 6，R 7，R 8，R 9，R 9， R 17，L 1，L 2，L 3和Q如说明书中所定义，和其药学上可接受的盐; 以及其制备方法，含有它们的组合物及其在治疗中的用途。这些化合物是一氧化氮合酶的抑制剂，因此特别可用于治疗或预防炎性疾病和疼痛。

32. 发明授权

US07119122B2 Compounds for the inhibition of nitric oxide synthase 失效
标题翻译：用于抑制一氧化氮合酶的化合物
公开(公告)号：US07119122B2
公开(公告)日：2006-10-10
申请号：US10491264
申请日：2002-10-02
申请人： Stephen Connolly , Glen Ernst
发明人： Stephen Connolly , Glen Ernst
IPC分类号： A61K31/137 , C07C211/04 , C07C211/52 , C07C209/08 , C07D207/06
CPC分类号： C07C323/32 , C07C217/58 , C07C217/90 , C07C255/54 , C07C2602/08 , C07C2602/10 , C07D213/85
摘要： There are provided novel compounds of formula (I) wherein A, R1, R3, R4, R5, T, U, V, W, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory diseases, pain and CNS diseases
摘要翻译：提供式（I）的新化合物，其中A，R 1，R 3，R 4，R 5， SUP>，T，U，V，W，X和Y如说明书中所定义，及其药学上可接受的盐; 以及其制备方法，含有它们的组合物及其在治疗中的用途。这些化合物是一氧化氮合酶的抑制剂，因此特别可用于治疗或预防炎性疾病，疼痛和CNS疾病

33. 发明申请

US20060200186A1 Adjustable access device for surgical procedures 审中-公开
公开(公告)号：US20060200186A1
公开(公告)日：2006-09-07
申请号：US11325275
申请日：2006-01-04
申请人： Connie Marchek , William Frasier , Anthony Carlone , Katherine Herard , Nicholas Pavento , Timothy Beardsley , John Malone , Sara Dziedzic , Sheryl Frank , Stephen Connolly , Sean Selover
发明人： Connie Marchek , William Frasier , Anthony Carlone , Katherine Herard , Nicholas Pavento , Timothy Beardsley , John Malone , Sara Dziedzic , Sheryl Frank , Stephen Connolly , Sean Selover
IPC分类号： A61M29/00
CPC分类号： A61B17/3421 , A61B17/0218 , A61B2017/00261 , A61B2017/00407 , A61B2017/3443 , A61B2017/3488 , A61B2017/349
摘要： An access device for providing access from a skin incision to a surgical site is described. The access device has a first section having a proximal end and a distal end defining a first path therethrough. The access device has a second section having a proximal end and a distal end defining a second path therethrough, the second section is movable relative to the first section, and the first and second sections cooperate to form a continuous path such that movement of the second section changes the length of the path.

34. 发明授权

US06900243B2 Phenylheteroalkylamine derivatives 失效
标题翻译：苯基杂烷基胺衍生物
公开(公告)号：US06900243B2
公开(公告)日：2005-05-31
申请号：US10204845
申请日：2001-02-20
申请人： David Cheshire , Stephen Connolly , David Cox , Antonio Mete
发明人： David Cheshire , Stephen Connolly , David Cox , Antonio Mete
IPC分类号： A61P1/00 , A61K31/04 , A61K31/135 , A61K31/138 , A61K31/277 , A61P1/02 , A61P1/04 , A61P1/18 , A61P9/02 , A61P9/10 , A61P11/00 , A61P11/06 , A61P11/08 , A61P15/08 , A61P17/00 , A61P17/04 , A61P17/06 , A61P17/16 , A61P19/02 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/10 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/04 , A61P37/08 , A61P43/00 , C07C213/02 , C07C217/20 , C07C217/44 , C07C253/30 , C07C255/54 , C07C319/20 , C07C323/25 , C07C323/62 , C07C217/18 , A61K31/237
CPC分类号： C07C323/25 , C07C217/20 , C07C217/44 , C07C255/54 , C07C323/62 , C07C2601/02 , C07C2601/08
摘要： There are provided novel compounds of formula (I), wherein R1, R2, X, Y, V, W and Z are as defined in the specification, and pharmaceutically acceptable salts thereof, and enantiomers and racemates thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease and pain.
摘要翻译：提供式（I）的新化合物，其中R 1，R 2，X，Y，V，W和Z如说明书中所定义，并且药学上其可接受的盐，及其对映体和外消旋体; 以及其制备方法，含有它们的组合物及其在治疗中的用途。这些化合物是一氧化氮合酶的抑制剂，因此特别可用于治疗或预防炎性疾病和疼痛。

35. 发明申请

US20050038431A1 Device for insertion of implants 有权
标题翻译：插入植入物的装置
公开(公告)号：US20050038431A1
公开(公告)日：2005-02-17
申请号：US10639782
申请日：2003-08-12
申请人： Charles Bartish , Jeff Brousseau , David Konieczynski , Stephen Connolly
发明人： Charles Bartish , Jeff Brousseau , David Konieczynski , Stephen Connolly
IPC分类号： A61F2/00 , A61F2/30 , A61F2/44 , A61F2/46 , A61B17/70
CPC分类号： A61F2/4465 , A61F2/4611 , A61F2002/30133 , A61F2002/30777 , A61F2002/30787 , A61F2002/30843 , A61F2002/4627 , A61F2002/4628 , A61F2230/0015
摘要： A device and method, which can be used for insertion of surgical implants, are provided in which the device includes a shaft having a proximal end and a distal end, and at least one moveable element. In a particular embodiment, the moveable element is disposed within a conduit defined by the shaft. The moveable element includes a leg extending through the conduit and a foot at an end of the leg proximal to the distal end of the shaft. The element is moveable relative to the shaft between a first position, wherein the foot extends beyond the distal end, and a second position, wherein the foot is substantially adjacent to the distal end. The device can further include a surgical implant that can be removably attached to the distal end.
摘要翻译：提供了可用于插入外科植入物的装置和方法，其中装置包括具有近端和远端的轴以及至少一个可移动元件。在特定实施例中，可移动元件设置在由轴限定的导管内。可移动元件包括延伸穿过导管的腿部和靠近轴的远端的腿的端部处的脚。所述元件可在第一位置和第二位置之间相对于所述轴移动，所述第一位置在所述第一位置和所述第二位置之间延伸，所述第二位置基本上与所述远端相邻。该装置还可以包括可移除地附接到远端的手术植入物。

36. 发明授权

US09025750B1 Method and apparatus for determining and utilizing local phone topography 有权
标题翻译：用于确定和利用本地电话地形的方法和装置
公开(公告)号：US09025750B1
公开(公告)日：2015-05-05
申请号：US11941572
申请日：2007-11-16
申请人： Stephen Connolly
发明人： Stephen Connolly
IPC分类号： H04M3/42 , H04M3/56 , H04L12/16 , H04Q11/00
CPC分类号： H04M3/56 , H04M7/006 , H04M2203/2094
摘要： A method, apparatus and computer program product for determining and utilizing local phone topography is presented. A first signal level for each of a plurality of telephone lines is determined, each of the telephone lines having a telephone of a plurality of telephones associated therewith. A new signal is initiated on another telephone line with an additional telephone. Next, a change in signal level is determined for each of the plurality of telephone lines and, based on the change in signal level for each of the plurality of telephone lines, a determination made regarding which telephones of the plurality of telephones are within a listening distance (also referred to herein as earshot) of the additional telephone. A topography is defined for the telephones and the additional telephone based on the determining which telephones are within a listening distance of the additional telephone.
摘要翻译：提出了一种用于确定和利用本地电话地形的方法，装置和计算机程序产品。确定多个电话线中的每一个的第一信号电平，每个电话线具有与其相关联的多个电话的电话。在另一条电话线上启动一条新信号，并附加一条电话。接下来，针对多个电话线中的每一个确定信号电平的变化，并且基于多个电话线中的每一个的信号电平的变化，确定关于多个电话的哪些电话在听力附加电话的距离（此处也称为听力）。基于确定哪些电话在附加电话的收听距离内，为电话和附加电话定义了形状。

37. 发明授权

US08997077B1 Systems and methods for remediating a defective uninstaller during an upgrade procedure of a product 有权
标题翻译：在产品的升级过程中修复有缺陷的卸载程序的系统和方法
公开(公告)号：US08997077B1
公开(公告)日：2015-03-31
申请号：US12557646
申请日：2009-09-11
申请人： Stephen Connolly
发明人： Stephen Connolly
IPC分类号： G06F9/44 , G06F17/30
CPC分类号： G06F17/30345 , G06F8/62 , G06F11/1433
摘要： A computer-implemented method for remediating a defective uninstaller during an upgrade of a product is described. A system is queried to identify the defective uninstaller. An executable application is streamed to a file in a temporary folder. The executable application is separate from the defective uninstaller. An internal database table is queried to generate a script file containing commands used to modify the defective uninstaller. The script file is executed with the executable application to modify the defective uninstaller.
摘要翻译：描述了在产品升级期间修复有缺陷的卸载程序的计算机实现的方法。查询系统以识别有缺陷的卸载程序。可执行应用程序被流式传输到临时文件夹中的文件。可执行应用程序与有缺陷的卸载程序是分开的。查询内部数据库表以生成包含用于修改有缺陷的卸载程序的命令的脚本文件。脚本文件与可执行应用程序一起执行，以修改有缺陷的卸载程序。

38. 发明授权

US07720217B1 Mute condition indicator 有权
标题翻译：静音状态指示灯
公开(公告)号：US07720217B1
公开(公告)日：2010-05-18
申请号：US11756175
申请日：2007-05-31
申请人： Stephen Connolly
发明人： Stephen Connolly
IPC分类号： H04M1/00 , H04M9/00
CPC分类号： H04M1/6041 , H04M1/72519 , H04M2250/62
摘要： A method and apparatus for providing a mute condition indicator is presented. In a communication set for a telephone, the communication set including a speaker and a microphone, a mute condition is indicated with an indicator disposed adjacent the microphone. The indicator is operable to indicate to a user of the communication set that a mute condition for the microphone is active while the user is using said communication set.
摘要翻译：提出了一种用于提供静音状况指示器的方法和装置。在用于电话的通信组中，包括扬声器和麦克风的通信组，静音状态用与麦克风相邻的指示器指示。指示符可操作以向用户指示通信集合，在用户正在使用所述通信集合时麦克风的静音条件是活动的。

39. 发明授权

US07594888B2 Expandable ports and methods for minimally invasive surgery 有权
标题翻译：用于微创手术的可扩展端口和方法
公开(公告)号：US07594888B2
公开(公告)日：2009-09-29
申请号：US11255784
申请日：2005-10-21
申请人： Douglas Raymond , Shinikequa White , Richard Pellegrino , Anthony Carlone , William Frasier , Connie Marchek , Brian Murphy , Stephen Connolly , Nicholas Pavento , Sara Dziedzic
发明人： Douglas Raymond , Shinikequa White , Richard Pellegrino , Anthony Carlone , William Frasier , Connie Marchek , Brian Murphy , Stephen Connolly , Nicholas Pavento , Sara Dziedzic
IPC分类号： A61B1/32
CPC分类号： A61B17/3439 , A61B17/02
摘要： An expandable port for minimally invasive surgery includes a first section, a second section, and at least one intermediate section. The port is expandable from a closed configuration in which the first section is proximate the second section along at least a portion of a length of the first section to an expanded configuration in which the first section is spaced apart from the second section. The intermediate portion spans a gap between the first section and the second section when the port is in the expanded configuration.
摘要翻译：用于微创手术的可扩展端口包括第一部分，第二部分和至少一个中间部分。该端口可从第一部分沿第一部分的长度的至少一部分附近到第二部分的第二部分的第二部分的第二部分的第二部分的第二部分的封闭构造扩展。当端口处于扩展配置时，中间部分跨越第一部分和第二部分之间的间隙。

40. 发明申请

US20080207698A1 Novel Compounds 569 失效
标题翻译：新化合物569
公开(公告)号：US20080207698A1
公开(公告)日：2008-08-28
申请号：US11959679
申请日：2007-12-19
申请人： Stephen Connolly , Alexander Humphries , Premji Meghani
发明人： Stephen Connolly , Alexander Humphries , Premji Meghani
IPC分类号： A61K31/428 , C07D277/68 , A61K31/4439 , A61P11/00 , C07D417/12
CPC分类号： C07D277/14 , C07D417/12
摘要： The present invention provides compounds of formula (I) wherein Ra, Rb, R1, R2, R3, R4, R5, R6 and R29 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
摘要翻译：本发明提供式（I）的化合物，其中R 1，R 2，R 1，R 2，R 2， R 3，R 4，R 5，R 6和R 29，如本说明书中所定义，其制备方法，含有它们的药物组合物及其在治疗中的用途。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式