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    • 31. 发明授权
    • Directional component measurement by echography
    • US5000184A
    • 1991-03-19
    • US407517
    • 1989-09-15
    • Odile Bonnefous
    • Odile Bonnefous
    • G01P13/00A61B8/06G01S7/526G01S15/50G01S15/58
    • G01S15/8984A61B8/06G01S15/582
    • A device for measuring one of the transverse components V.sub.x of the speed of moving organs and blood flows by means of ultrasonic echography, the axial component V.sub.z, oriented parallel to the axis O.sub.z of the ultrasonic beam, being measured by a first intercorrelation circuit (51.sub.z) which operates with a sampling step .DELTA.T and which supplies, on the basis of two successive echographic lines shifted through k.DELTA.T, (k=-I, -I+1, . . . , I), 2I+1 correlation function values according to z, a first maximum-value searching circuit (53.sub.z) which supplies the value I.sub.o of k which corresponds to the largest value of said correlation functions according to z. The device includes:a bidimensional mosaic (10) of piezoelectric transducers which are centered around the origin O of a system of axes O.sub.x, O.sub.y which forms a trihedron with said axis O.sub.z,a circuit (20) for forming 2N.sub.x +1 receiving channels which correspond to the beams centered around (k.sub.x p.sub.x,O,O), where k.sub.x =-N.sub.x, -N.sub.x +1, . . . , N.sub.x and p.sub.x is the pitch of the channels according to x,a buffer memory (50) in which there are stored the echographic signals received by each of the 2N.sub.x +1 receiving channels, taken for the values I.sub.o -1, I.sub.o, I.sub.o +1 of k,a second circuit (51.sub.x) for intercorrelation between a signal received by the central receiving channel (O,O,O) and the next signal received by the receiving channel (k.sub.x p.sub.x, O,O) supplying the three intercorrelation functions C.sub.x (k.sub.x p.sub.x,O,(I.sub.o -1).DELTA.T), c.sub.x (k.sub.x p.sub.x,O,I.sub.o .DELTA.T), C.sub.x (k.sub.x p.sub.x,O,(I.sub.o +1).DELTA.T),a circuit (53.sub.x) for linear interpolation in x which supplies, on the basis of said 3 intercorrelation functions, the correlation peak C.sub.x (k.sub.x p.sub.x) according to x,a second maximum-value searching circuit (54.sub.x), which supplies, on the basis of the 2N.sub.x +1 values of k.sub.x, the value k.sub.xo for which C.sub.x (k.sub.x p.sub.x) is maximum, the tranverse component V.sub.x satisfying the equation:V.sub.x =k.sub.xo p.sub.x /T where T is the recurrent period of the echographic signals.Application: the formation of echographic images of moving organs and blood flows.
    • 32. 发明申请
    • ULTRASONIC IMAGING SYSTEM AND METHOD
    • 超声成像系统及方法
    • US20090219301A1
    • 2009-09-03
    • US12089931
    • 2006-10-20
    • Olivier GerardOdile BonnefousPascal AllainEric DenisEric M.G.JP. SalouxCecile A.M. Marboeuf
    • Olivier GerardOdile BonnefousPascal AllainEric DenisEric M.G.JP. SalouxCecile A.M. Marboeuf
    • G09G5/00
    • G06T7/20A61B8/483G06T7/0012
    • The present invention relates to an ultrasonic imaging system for evaluating and displaying a deformation of a body organ. A sequence of image data sets comprising at least a first image data set and a second image data set of echographic data is acquired. A motion vector field is calculated between image points of the second image data set and image points of the first image data set. A reference point is chosen within or outside the first and second image data sets. A first scanline is defined, which comprises said reference point. A motion vector of an image point is projected onto the defined first scanline, which provides a projected tissue velocity along the first scanline. The projected tissue velocity is used for evaluating a ID component of a deformation of the body organ at the image point along the direction of the first scanline. Such a ID component of a deformation of the body organ, for example a strain rate or a strain, is further rendered in a graphical representation of the sequence of image data sets.
    • 本发明涉及一种用于评估和显示身体器官变形的超声波成像系统。 获取包括至少第一图像数据组和第二图像数据组的回波图像数据的序列的图像数据集。 在第二图像数据组的图像点和第一图像数据集合的图像点之间计算运动矢量场。 在第一和第二图像数据集内或外部选择参考点。 定义第一扫描线,其包括所述参考点。 图像点的运动矢量被投影到所定义的第一扫描线上,其提供沿着第一扫描线的投影组织速度。 投影的组织速度用于评估沿着第一扫描线的方向的图像点处的身体器官的变形的ID分量。 身体器官的变形的这种ID分量,例如应变速率或应变,进一步以图像数据集的序列的图形表示形式。
    • 33. 发明申请
    • Ultrasonic doppler system for determining movement of artery walls
    • 用于确定动脉壁移动的超声多普勒系统
    • US20060210130A1
    • 2006-09-21
    • US10538154
    • 2003-12-12
    • Laurence Germond-RouetOdile Bonnefous
    • Laurence Germond-RouetOdile Bonnefous
    • G06K9/00
    • A61B8/08A61B8/488
    • The invention relates to an ultrasonic viewing system, for displaying images of an artery using a curved array of transducer elements, comprising means for acquiring (51) of an ultrasonic image sequence and a Doppler color sequence of a segment of artery explored along its longitudinal axis and having walls moving in relation with the cardiac cycle; and comprising processing means for: estimating the velocity and motion amplitude (53, 54, 55) of the artery walls along Doppler color ultrasound scanning lines; estimating the motion amplitude (58) of the artery walls along lines perpendicular to the artery global axis; and further comprising: display means for displaying (60) curves of this last artery wall amplitude on a dedicated display on which the user may have interaction. The invention further relates to an image processing method having steps to be carried out using this system.
    • 本发明涉及一种用于使用换能器元件的弯曲阵列显示动脉的图像的超声波观察系统,包括用于获取(51)超声图像序列和沿着其纵向轴线探索的动脉段的多普勒色彩序列的装置 并且具有与心动周期相关的壁; 并且包括处理装置,用于:估计沿着多普勒彩色超声扫描线的动脉壁的速度和运动幅度(53,54,55); 沿垂直于动脉总轴的线估计动脉壁的运动幅度(58); 并且还包括:显示装置,用于在用户可能具有交互的专用显示器上显示(60)该最后动脉壁振幅的曲线。 本发明还涉及一种具有使用该系统执行的步骤的图像处理方法。
    • 34. 发明授权
    • Ultrasonic method and system for shear wave parameter estimation
    • 用于剪切波参数估计的超声波方法和系统
    • US06561981B2
    • 2003-05-13
    • US09840201
    • 2001-04-23
    • Odile Bonnefous
    • Odile Bonnefous
    • A61B800
    • A61B8/08A61B8/0858A61B8/485
    • The invention relates to an ultrasonic diagnostic imaging method for determining propagation parameters of transient shear wave front, comprising steps of forming transient shear waves in a tissue (5), acquiring ultrasonic image data (S,S*) of the tissue, along image lines (l), during a time delay (TSW) for a transient shear wave front to propagate over a depth (z) in said tissue, estimating the tissue velocity (V) for each line, constructing a tissue velocity image sequence [I(V)] from the ultrasonic data (S,S*) and the tissue velocities (V) on the lines, and deriving the velocities (CSW) of the shear wave front at instants of the sequence. Tissue parameters such as elasticity are then calculated from said front velocity. The invention also relates to an ultrasonic diagnostic imaging system having processing means (100, PROCESSING1, PROCESSING2) for carrying out this method. The processing means may be a computer program product having instruction to this end.
    • 本发明涉及一种用于确定瞬时剪切波前的传播参数的超声诊断成像方法,包括在组织(5)中形成瞬时剪切波的步骤,沿着图像线获取组织的超声图像数据(S,S *) (1),在瞬时剪切波前的延时(TSW)期间在所述组织中的深度(z)上传播,估计每行的组织速度(V),构建组织速度图像序列[I(V )]从线上的超声数据(S,S *)和组织速度(V),并推导出序列时刻的剪切波前的速度(CSW)。 然后从所述前方速度计算诸如弹性的组织参数。 本发明还涉及具有用于执行该方法的处理装置(100,处理1,处理2)的超声诊断成像系统。 处理装置可以是具有此目的的指令的计算机程序产品。
    • 35. 发明授权
    • Method and device for determining the compliance and the blood pressure
of an artery by ultrasonic echography
    • 用于通过超声回波测定来确定动脉的顺应性和血压的方法和装置
    • US6113543A
    • 2000-09-05
    • US77414
    • 1998-09-02
    • Odile Bonnefous
    • Odile Bonnefous
    • A61B5/0205A61B5/022A61B8/04A61B8/06G01F1/66G01S15/89A61B8/00
    • A61B5/02007A61B8/06G01S15/8979G01S7/52042
    • The invention relates to an ultrasonic echograph apparatus and method for locally determining biological data constituted by the time varying part of the blood pressure and the arterial wall compliance variations in function of the arterial radius variations, and includes the steps of measuring blood flow rate, arterial radius variation, and the mean arterial radius variation for two neighboring excitation lines and a hydrodynamic inductance. The method further includes steps of modelling, based on the measures, arterial wall behaviors by arterial wall stress-strain laws according to parametric relationships giving the biological data to determine, in the case of purely elastic or visco-elastic arterial behavior the parameters of the parametric relationships being related to the arterial dilatation and contraction phases over a whole cardiac cycle.
    • PCT No.PCT / IB97 / 01180 Sec。 371日期:1998年9月2日 102(e)1998年9月9日PCT 1997年9月27日PCT公布。 公开号WO98 / 14119 日期:1998年04月9日本发明涉及一种用于局部确定由血压的时变部分和动脉半径变化的动脉壁依从性变化构成的生物数据的超声波回波仪装置和方法,包括以下步骤: 血流速度,动脉半径变化和两个相邻激励线的平均动脉半径变化和流体动力学电感。 该方法还包括以下步骤:基于措施,根据参数关系通过动脉壁应力 - 应变定律对动脉壁行为进行建模,给出生物数据,以确定在纯弹性或粘弹性动脉行为的情况下, 参数关系与整个心动周期的动脉扩张和收缩期有关。
    • 37. 发明授权
    • Device for measurement and display of physiological parameters of a
blood flow by ultrasonic echography
    • 通过超声波信号测量和显示血液流动生理参数的装置
    • US5103826A
    • 1992-04-14
    • US619276
    • 1990-11-28
    • Odile Bonnefous
    • Odile Bonnefous
    • A61B8/06G01S15/58
    • A61B8/06G01S15/582
    • A device for the measurement and display of physiological parameters of a blood flow (10), comprising a unit (300) for measuring, using ultrasonic echography, the speed V(t,z) of blood flow as a function of time t and scanning depth z. The measurement of the speed V(t,z) is independent of the frequency of the ultrasonic wave used. The device for measurment and display comprises, connected to an output of a first memory (304) for storing speed values V(t,z), a multiplexer (401) which writes, for a given instant t, the number N.sub.i (t) of measurement samples having the value V.sub.i to within .DELTA.V, .DELTA.V being the discretization step, into a register i of a second memory (402) and a device (403) for displaying the speed as a function of time, such that the brightness at the point (Vi,t) is proportional to N.sub.i (t).
    • 一种用于测量和显示血流(10)的生理参数的装置,包括用于使用超声波回波造影测量血流速度V(t,z)作为时间t的函数的单位(300)和扫描 深度z。 速度V(t,z)的测量与所使用的超声波的频率无关。 用于测量和显示的装置包括连接到用于存储速度值V(t,z)的第一存储器(304)的输出,多路复用器(401)在给定时刻t写入数目Ni(t) 将具有值V i的DELTA V,DELTA V作为离散化步骤的测量样本转换成第二存储器(402)的寄存器i和用于显示作为时间的函数的速度的装置(403),使得亮度 (Vi,t)与Ni(t)成正比。