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31. 发明授权

US08857438B2 Devices and methods for acoustic shielding 有权
标题翻译：声屏蔽装置和方法
公开(公告)号：US08857438B2
公开(公告)日：2014-10-14
申请号：US13291312
申请日：2011-11-08
申请人： Peter G. Barthe , Michael H. Slayton , Charles D. Emery
发明人： Peter G. Barthe , Michael H. Slayton , Charles D. Emery
IPC分类号： A61F13/00
CPC分类号： A61F9/045 , A61B3/00 , A61B6/107 , A61B6/4423 , A61B8/00 , A61B8/44 , A61B90/04 , A61B2090/0445 , A61B2090/0454 , A61B2090/0472 , A61F9/00 , A61F9/04 , A61N7/00 , G10K11/04 , G10K11/168
摘要： Acoustic shielding system and method for protecting and shielding non-targeted regions or tissues that are not intended to be treated by ultrasonic procedures from acoustic energy using a shield. In some embodiments, the shield comprises multiple layers made of one or more materials with one or more acoustic impedances. In some embodiments a multilayered shield includes materials with relatively different acoustic impedance levels. In some embodiments, the shield includes active components such as energy diversion devices, heating, cooling, monitoring, and/or sensing. In some embodiments, the shield is configured to protect an eye, mouth, nose or ear while allowing the ultrasound to treat the surrounding tissue. One embodiment of an eye shield is configured to fit under at least one eyelid and over a portion of the eye.
摘要翻译：声屏蔽系统和用于保护和屏蔽非目标区域或组织的方法，所述非目标区域或组织不希望通过超声波程序使用屏蔽从声能处理。在一些实施例中，屏蔽包括由具有一个或多个声阻抗的一种或多种材料制成的多层。在一些实施例中，多层屏蔽包括具有相对不同的声阻抗水平的材料。在一些实施例中，屏蔽件包括诸如能量分流装置，加热，冷却，监测和/或感测的有源部件。在一些实施例中，护罩被配置为保护眼睛，嘴，鼻子或耳朵，同时允许超声波治疗周围组织。眼罩的一个实施例被配置成装配在至少一个眼睑和眼睛的一部分上方。

32. 发明申请

US20140236049A1 SYSTEM AND METHOD FOR VARIABLE DEPTH ULTRASOUND TREATMENT 审中-公开
标题翻译：用于可变深度超声治疗的系统和方法
公开(公告)号：US20140236049A1
公开(公告)日：2014-08-21
申请号：US14264732
申请日：2014-04-29
申请人： Peter G. Barthe , Michael H. Slayton
发明人： Peter G. Barthe , Michael H. Slayton
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61B34/30 , A61B2017/22024 , A61B2017/22028 , A61N2007/0065 , A61N2007/0069 , A61N2007/0073 , A61N2007/0095
摘要： A non-invasive variable depth ultrasound treatment method and system comprises a variable depth transducer system configured for providing ultrasound treatment to a patient. An exemplary variable depth transducer system can comprise a transducer configured to provide treatment to more than one region of interest, such as between a deep treatment region of interest and a superficial region of interest, and/or a subcutaneous region of interest. The variable depth transducer can comprise a transduction element having a piezoelectrically active layer, matching layers and/or other materials far generating radiation or acoustical energy. The variable depth transducer may be configured to operate at moderate frequencies within the range from approximately 750 kHz to 20 MHz or more. In addition, the transduction element may be configured with a variable depth device comprising one or more materials configured to allow tor control and focusing/defocusing of the acoustic energy to more than one region of interest.
摘要翻译：非侵入性可变深度超声治疗方法和系统包括被配置为向患者提供超声治疗的可变深度换能器系统。示例性可变深度换能器系统可以包括被配置为向多于一个感兴趣的区域提供治疗的换能器，例如感兴趣的深部治疗区域和感兴趣的表面区域和/或感兴趣的皮下区域之间。可变深度换能器可以包括具有压电有源层，匹配层和/或远远地产生辐射或声能的其它材料的换能元件。可变深度换能器可以被配置为在大约750kHz至20MHz或更大的范围内的中等频率下操作。另外，转导元件可以配置有可变深度装置，该可变深度装置包括一种或多种材料，其被配置为允许电极控制和将声能聚焦/散焦到多于一个感兴趣的区域。

33. 发明授权

US08641622B2 Method and system for treating photoaged tissue 有权
标题翻译：光电组织治疗方法及系统
公开(公告)号：US08641622B2
公开(公告)日：2014-02-04
申请号：US13230498
申请日：2011-09-12
申请人： Peter G. Barthe , Michael H. Slayton , Inder Raj S. Makin
发明人： Peter G. Barthe , Michael H. Slayton , Inder Raj S. Makin
IPC分类号： A61B8/00
CPC分类号： A61N7/02 , A61B5/682 , A61B5/6842 , A61B8/08 , A61B8/0858 , A61B8/12 , A61B8/13 , A61B8/4209 , A61B8/4281 , A61B8/4455 , A61B8/4483 , A61B8/461 , A61B8/483 , A61B8/546 , A61B17/320068 , A61H23/0245 , A61H2201/5007 , A61N7/00 , A61N2007/0008 , A61N2007/0034 , A61N2007/0052 , A61N2007/027 , G01S15/8909
摘要： A method and system for ultrasound treatment of photoaged tissue are provided. An exemplary method and system are configured for first, ultrasound imaging of the region of interest for localization of the treatment area, second, delivery of ultrasound energy at a depth and pattern to achieve the desired therapeutic effects, and third to monitor the treatment area during and after therapy to assess the results and/or provide feedback. The exemplary treatment method and system can be configured for producing arrays of sub-millimeter and larger zones of thermal ablation to treat the epidermal, superficial dermal, mid-dermal and deep dermal components of photoaged tissue.
摘要翻译：提供了一种用于光电组织超声处理的方法和系统。一种示例性方法和系统被配置用于首先对感兴趣区域的超声成像进行治疗区域的定位，其次，以深度和图案递送超声能量以获得期望的治疗效果，第三，监测治疗区域的治疗区域并在治疗后评估结果和/或提供反馈。可以将示例性治疗方法和系统配置用于产生亚毫米和更大的热消融区域阵列，以治疗光化组织的表皮，浅表皮肤，中间皮肤和深层真皮成分。

34. 发明授权

US08366622B2 Treatment of sub-dermal regions for cosmetic effects 有权
标题翻译：治疗亚皮肤区域的化妆品效果
公开(公告)号：US08366622B2
公开(公告)日：2013-02-05
申请号：US13444336
申请日：2012-04-11
申请人： Michael H. Slayton , Peter G. Barthe , Inder Raj S. Makin , Brian D. O'Connor
发明人： Michael H. Slayton , Peter G. Barthe , Inder Raj S. Makin , Brian D. O'Connor
IPC分类号： A61B7/02
CPC分类号： A61N7/02 , A61B5/682 , A61B5/6842 , A61B8/08 , A61B8/0858 , A61B8/12 , A61B8/13 , A61B8/4209 , A61B8/4281 , A61B8/4455 , A61B8/4483 , A61B8/461 , A61B8/483 , A61B8/546 , A61B17/320068 , A61H23/0245 , A61H2201/5007 , A61N7/00 , A61N2007/0008 , A61N2007/0034 , A61N2007/0052 , A61N2007/027 , G01S15/8909
摘要： A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.
摘要翻译：公开了一种用于无创面部提升和深层组织紧固的方法和系统。配置了用于成像，监测和热损伤以处理SMAS区域的示例性方法和处理系统。根据示例性实施例，示例性方法和系统被配置为通过首先对感兴趣区域进行成像以对治疗区域和周围结构进行定位来处理SMAS区域;其次，在深度，分布处输送超声能量，时间和能量水平，以达到预期的治疗效果，第三是监测治疗前，治疗期间和治疗后的治疗区域，以计划和评估结果和/或提供反馈。

35. 发明申请

US20120035475A1 METHODS FOR NON-INVASIVE COSMETIC TREATMENT OF THE EYE REGION 审中-公开
标题翻译：眼部非侵入性化妆品治疗方法
公开(公告)号：US20120035475A1
公开(公告)日：2012-02-09
申请号：US13245864
申请日：2011-09-27
申请人： Peter G. Barthe , Michael H. Slayton
发明人： Peter G. Barthe , Michael H. Slayton
IPC分类号： A61N7/00 , A61B8/00
CPC分类号： A61B8/4461 , A61B8/0858 , A61B8/13 , A61B8/4209 , A61B8/4272 , A61B8/4438 , A61B8/4455 , A61B34/10 , A61B2017/00106 , A61B2017/00769 , A61B2018/00577 , A61B2090/378 , A61N7/00 , A61N7/02 , A61N2007/0008 , A61N2007/0034 , A61N2007/0052 , A61N2007/006 , A61N2007/0065 , A61N2007/0082 , A61N2007/0091
摘要： Embodiments of a dermatological cosmetic treatment and imaging system and method can include use of a hand wand and a removable transducer module having an ultrasound transducer. The system can include a control module that is coupled to the hand wand and has a graphical user interface for controlling the removable transducer module, and an interface coupling the hand wand to the control module. In some embodiments, the cosmetic treatment system may be used in cosmetic procedures on at least a portion of a face, head, neck, body, and/or other part of a patient for a face lift, a brow lift, a chin lift, an eye treatment, a wrinkle reduction, a scar reduction, a burn treatment, a tattoo removal, a skin tightening, a vein reduction, a treatment on a sweat gland, a treatment of hyperhidrosis, a sun spot removal, a fat treatment, a vaginal rejuvenation, and/or an acne treatment.
摘要翻译：皮肤病学美容治疗和成像系统和方法的实施例可以包括使用具有超声换能器的手杖和可移除换能器模块。该系统可以包括耦合到手杖的控制模块，并且具有用于控制可拆卸换能器模块的图形用户界面，以及将手杖连接到控制模块的接口。在一些实施方案中，美容治疗系统可以用于面部，头部，颈部，身体和/或患者的其他部分的至少一部分上的美容程序，用于面部提升，眉毛提升，下巴提升，眼睛治疗，皱纹减轻，疤痕减少，烧伤治疗，纹身去除，皮肤收紧，静脉减少，汗腺治疗，多汗症的治疗，太阳斑去除，脂肪治疗，阴道复兴，和/或痤疮治疗。

36. 发明授权

US07846096B2 Method for monitoring of medical treatment using pulse-echo ultrasound 有权
标题翻译：使用脉冲回波超声检查治疗方法
公开(公告)号：US07846096B2
公开(公告)日：2010-12-07
申请号：US10721034
申请日：2003-11-24
申请人： T. Douglas Mast , Waseem Faidi , Inder Raj S. Makin , Peter G. Barthe , Michael H. Slayton
发明人： T. Douglas Mast , Waseem Faidi , Inder Raj S. Makin , Peter G. Barthe , Michael H. Slayton
IPC分类号： A61B8/00
CPC分类号： A61B8/08 , A61B8/12 , A61B8/14 , A61B8/4488 , A61B8/5207 , A61B8/5238 , A61B8/5276 , A61B10/0233 , A61B17/22012 , A61B17/2202 , A61B17/29 , A61B17/320092 , A61B2090/378 , A61B2090/3784 , A61B2090/3929 , A61B2090/3975 , A61N7/022 , A61N2007/0078 , G01S15/899
摘要： A method for ultrasound imaging of anatomical tissue. A first signal is received from a first imaging ultrasound wave which has been reflected from a location in the anatomical tissue during a first time period. A second signal is received from a second imaging ultrasound wave which has been reflected from the location in the anatomical tissue during a later second time period, following a discrete medical treatment. The second signal is subtracted from the first signal to form a difference signal. The difference signal may be scaled, spatially filtered, then used to generate an indication, the indication showing the effect of the medical treatment in the location in the anatomical tissue.
摘要翻译：解剖组织超声成像的方法。从第一时间段内从解剖组织中的位置反射的第一成像超声波接收第一信号。在离散的医疗处理之后，在稍后的第二时间段内已经从解剖组织中的位置反射的第二成像超声波接收第二信号。从第一信号中减去第二信号以形成差分信号。差分信号可以被缩放，空间过滤，然后用于产生指示，该指示表示在解剖组织中的位置处的医疗的影响。

37. 发明申请

US20100280420A1 SYSTEM AND METHOD FOR VARIABLE DEPTH ULTRASOUND TREATMENT 有权
标题翻译：用于可变深度超声治疗的系统和方法
公开(公告)号：US20100280420A1
公开(公告)日：2010-11-04
申请号：US12834754
申请日：2010-07-12
申请人： Peter G. Barthe , Michael H. Slayton
发明人： Peter G. Barthe , Michael H. Slayton
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61B34/30 , A61B2017/22024 , A61B2017/22028 , A61N2007/0065 , A61N2007/0069 , A61N2007/0073 , A61N2007/0095
摘要： A non-invasive variable depth ultrasound treatment method and system comprises a variable depth transducer system configured for providing ultrasound treatment to a patient. An exemplary variable depth transducer system can comprise a transducer configured to provide treatment to more than one region of interest, such as between a deep treatment region of interest and a superficial region of interest, and/or a subcutaneous region of interest. The variable depth transducer can comprise a transduction element having a piezoelectrically active layer, matching layers and/or other materials for generating radiation or acoustical energy. The variable depth transducer may be configured to operate at moderate frequencies within the range from approximately 750 kHz to 20 MHz or more. In addition, the transduction element may be configured with a variable depth device comprising one or more materials configured to allow for control and focusing/defocusing of the acoustic energy to more than one region of interest.
摘要翻译：非侵入性可变深度超声治疗方法和系统包括被配置为向患者提供超声治疗的可变深度换能器系统。示例性可变深度换能器系统可以包括被配置为向多于一个感兴趣的区域提供治疗的换能器，例如感兴趣的深部治疗区域和感兴趣的表面区域和/或感兴趣的皮下区域之间。可变深度换能器可以包括具有压电有源层，匹配层和/或用于产生辐射或声能的其它材料的换能元件。可变深度换能器可以被配置为在大约750kHz至20MHz或更大的范围内的中等频率下操作。另外，换能元件可以配置有可变深度装置，该可变深度装置包括一种或多种材料，其被配置为允许将声能控制和聚焦/散焦到多于一个感兴趣的区域。

38. 发明申请

US20100256490A1 MEDICAL SYSTEM HAVING AN ULTRASOUND SOURCE AND AN ACOUSTIC COUPLING MEDIUM 审中-公开
标题翻译：具有超声波源和声学耦合介质的医疗系统
公开(公告)号：US20100256490A1
公开(公告)日：2010-10-07
申请号：US12818261
申请日：2010-06-18
申请人： Inder Raj S. Makin , T. Douglas Mast , Michael H. Slayton , Peter G. Barthe , Jeffrey D. Messerly , Waseem Faidi , Megan M. Runk
发明人： Inder Raj S. Makin , T. Douglas Mast , Michael H. Slayton , Peter G. Barthe , Jeffrey D. Messerly , Waseem Faidi , Megan M. Runk
IPC分类号： A61N7/00 , A61B8/00
CPC分类号： A61B8/4272 , A61B8/12 , A61B8/4281 , A61B8/4444 , A61B8/546 , A61B2017/2253 , A61N7/00 , A61N7/022 , A61N2007/0052
摘要： An ultrasound medical system has an end effector including a medical ultrasound transducer and an acoustic coupling medium. The acoustic coupling medium has a transducer-proximal surface and a transducer-distal surface. The medical ultrasound transducer is positioned to emit medical ultrasound through the acoustic coupling medium from the transducer-proximal surface to the transducer-distal surface. The end effector is adapted to change a property (such as the shape and/or the temperature) of the acoustic coupling medium during emission, and/or between emissions, of medical ultrasound from the medical ultrasound transducer during a medical procedure on a patient. In one example, such changes are used to change the focus and/or beam angle of the emitted ultrasound during the medical procedure.
摘要翻译：超声波医疗系统具有包括医用超声波换能器和声耦合介质的末端执行器。声耦合介质具有换能器近侧表面和换能器远侧表面。医疗超声换能器被定位成通过声耦合介质从换能器近端表面到换能器远侧表面发射医用超声波。端部执行器适于在医疗超声波换能器在患者的医疗过程期间改变声学耦合介质在发射期间和/或发射之间的医疗超声波的性质（例如形状和/或温度）。在一个示例中，这样的改变用于在医疗过程期间改变发射的超声的焦点和/或束角。

39. 发明授权

US07806839B2 System and method for ultrasound therapy using grating lobes 有权
标题翻译：使用栅瓣的超声治疗系统和方法
公开(公告)号：US07806839B2
公开(公告)日：2010-10-05
申请号：US10867170
申请日：2004-06-14
申请人： T. Douglas Mast , Waseem Faidi , Inder Raj S. Makin , Peter G. Barthe , Michael H. Slayton
发明人： T. Douglas Mast , Waseem Faidi , Inder Raj S. Makin , Peter G. Barthe , Michael H. Slayton
IPC分类号： A61H1/00 , A61H1/02 , A61H5/00
CPC分类号： A61N7/022 , A61N2007/0065 , A61N2007/0078 , A61N2007/0095 , A61N2007/027
摘要： A system and method for medical treatment of tissue using ultrasound. The system comprises a probe having an array of transducer elements, an ultrasound waveform generator adapted to generate at least one electrical ultrasound signal, and a plurality of phase controls, each coupled to the ultrasound waveform generator and adapted to generate from the electrical ultrasound signal a phase-shifted drive signal that is coupled to an associated transducer element. The drive signal is effective to control grating lobe foci emitted by the array. The method employs the system.
摘要翻译：一种使用超声波治疗组织的系统和方法。该系统包括具有换能器元件阵列的探头，适于产生至少一个电超声波信号的超声波波形发生器，以及多个相位控制器，每个相位控制器耦合到超声波波形发生器，并适于从电超声波信号耦合到相关联的换能器元件的相移驱动信号。驱动信号有效地控制由阵列发射的光栅叶片焦点。该方法采用该系统。

40. 发明授权

US07758524B2 Method and system for ultra-high frequency ultrasound treatment 有权
标题翻译：超高频超声治疗方法与系统
公开(公告)号：US07758524B2
公开(公告)日：2010-07-20
申请号：US11245999
申请日：2005-10-06
申请人： Peter G. Barthe , Michael H. Slayton
发明人： Peter G. Barthe , Michael H. Slayton
IPC分类号： A61H1/00
CPC分类号： A61B17/320068 , A61B8/00 , A61H23/0245 , A61N7/02 , A61N2007/0034 , A61N2007/0052
摘要： A non-invasive ultra-high frequency ultrasound treatment method and system are provided. An exemplary method and system comprise a high-frequency ultrasound transducer system configured for providing ultrasound treatment to a patient such that the superficial and/or subcutaneous regions of the patient can be treated. An exemplary high-frequency ultrasound transducer system comprises a control system and a transducer configured to provide treatment to the superficial and/or subcutaneous regions of interest. The high-frequency ultrasound transducer may be configured to operate at higher frequencies and controlled power levels to provide treatment to the superficial and/or subcutaneous regions of interest. For example, higher frequencies within the range from approximately 20 MHz to 500 MHz or more may be utilized.
摘要翻译：提供了非侵入式超高频超声处理方法和系统。示例性方法和系统包括被配置为向患者提供超声治疗使得可以治疗患者的浅表和/或皮下区域的高频超声换能器系统。示例性的高频超声换能器系统包括控制系统和被配置为向感兴趣的表面和/或皮下区域提供治疗的换能器。高频超声换能器可以被配置为在更高的频率和受控的功率水平下操作以对感兴趣的表面和/或皮下区域提供治疗。例如，可以使用在大约20MHz至500MHz或更大的范围内的较高频率。

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