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31. 发明申请

US20100261699A1 N-PYRAZOLE-2-PYRIDINE CARBOXAMIDE DERIVATIVE 审中-公开
标题翻译： N-吡咯-2-吡啶酰胺衍生物
公开(公告)号：US20100261699A1
公开(公告)日：2010-10-14
申请号：US12746567
申请日：2008-12-15
申请人： Noriaki Hashimoto , Teruyuki Nishimura , Yufu Sagara
发明人： Noriaki Hashimoto , Teruyuki Nishimura , Yufu Sagara
IPC分类号： A61K31/4439 , C07D401/14 , A61P3/10
CPC分类号： A61K31/155 , A61K31/427 , A61K31/44 , A61K31/4439 , A61K31/444 , A61K38/28 , A61K38/31 , C07D401/14 , A61K2300/00
摘要： The present invention relates to a compound represented by the formula: or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are each independently a lower alkyl group, X is CH or the like, and X1 is an aminoalkoxy group or the like, which has a glucokinase-activating effect and thus is useful in the treatment of diabetes, obesity, and the like.
摘要翻译：本发明涉及由下式表示的化合物或其药学上可接受的盐，其中R1和R2各自独立地为低级烷基，X为CH等，X1为氨基烷氧基等，其具有葡糖激酶活化作用，因此可用于治疗糖尿病，肥胖症等。

32. 发明授权

US08559111B2 Interference filter having adhesive and warp reduction grooves 失效
标题翻译：具有粘合剂和经线缩减槽的干涉滤光器
公开(公告)号：US08559111B2
公开(公告)日：2013-10-15
申请号：US12887596
申请日：2010-09-22
申请人： Teruyuki Nishimura , Akira Sano
发明人： Teruyuki Nishimura , Akira Sano
IPC分类号： G02B27/00
CPC分类号： G02B26/001 , G01J3/26 , G01J3/51
摘要： An interference filter includes: a first substrate; a second substrate that faces one side of the first substrate and is bonded to the first substrate; a first reflection film formed on the side of the first substrate that faces the second substrate; and a second reflection film provided on the second substrate and faces the first reflection film, the first substrate including a first gap formation region in which the first reflection film is disposed and which is not contact with the second substrate, and wherein the first substrate and the second substrate are adhesively bonded to each other with the adhesive applied into the adhesive grooves with the first bonding region and the second bonding region bonded to each other.
摘要翻译：干涉滤光器包括：第一基板; 第二基板，其面向所述第一基板的一侧并且接合到所述第一基板; 形成在所述第一基板的面向所述第二基板的一侧的第一反射膜; 以及第二反射膜，设置在所述第二基板上并且面对所述第一反射膜，所述第一基板包括第一间隙形成区域，所述第一间隙形成区域设置有所述第一反射膜并且不与所述第二基板接触，并且其中所述第一基板和第二基板通过将粘合剂施加到具有第一接合区域和第二接合区域的粘合剂槽中的粘合剂彼此粘合。

33. 发明申请

US20100087360A1 Heterocycle-substituted benzimidazole derivative 有权
标题翻译：杂环取代的苯并咪唑衍生物
公开(公告)号：US20100087360A1
公开(公告)日：2010-04-08
申请号：US11988592
申请日：2006-07-12
申请人： Yoshio Ogino , Katsumasa Nonoshita , Teruyuki Nishimura , Jun-ichi Eike
发明人： Yoshio Ogino , Katsumasa Nonoshita , Teruyuki Nishimura , Jun-ichi Eike
IPC分类号： A61K38/28 , C07D401/14 , A61K31/4439 , C07D413/14 , C07D403/02 , A61K31/497 , A61K31/444 , A61P3/10 , A61P3/04
CPC分类号： C07D409/14 , C07D401/14 , C07D405/14 , C07D413/14
摘要： A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein X1 to X4 independently represent a carbon atom or the like; the ring A represents a 5- to 6-membered heteroaryl having 1 to 4 heteroatoms independently selected from the group consisting of a nitrogen atom, a sulfur atom and an oxygen atom; X5 represents an oxygen atom or the like; X represents a carbon atom or the like; Het represents a 5- or 6-membered aliphatic heterocycle; R1 represents an aryl or the like; R2 represents a formyl group or the like; and R3 represents a —C1-6 alkyl or the like. The compound or salt has a glucokinase activation effect and is useful as a therapeutic agent for diabetes.
摘要翻译：由式（I）表示的化合物或其药学上可接受的盐：（I）其中X 1至X 4独立地表示碳原子等; 环A表示具有1至4个独立地选自氮原子，硫原子和氧原子的杂原子的5-至6-元杂芳基; X 5表示氧原子等; X表示碳原子等; Het代表5-或6-元脂族杂环; R1表示芳基等; R2表示甲酰基等; 并且R 3表示-C 1-6烷基等。化合物或盐具有葡糖激酶活化作用，可用作糖尿病的治疗剂。

34. 发明申请

US20060167053A1 Heteroarylcarbamoylbenzene derivative 有权
标题翻译：杂芳基氨基甲酰基苯衍生物
公开(公告)号：US20060167053A1
公开(公告)日：2006-07-27
申请号：US10546962
申请日：2004-02-26
申请人： Tomoharu IIno , Noriaki Hashimoto , Hiroshi Nakashima , Keiji Takahashi , Teruyuki Nishimura , Junichi Eiki
发明人： Tomoharu IIno , Noriaki Hashimoto , Hiroshi Nakashima , Keiji Takahashi , Teruyuki Nishimura , Junichi Eiki
IPC分类号： A61K31/454 , A61K31/433 , A61K31/426 , A61K31/42 , A61K31/41
CPC分类号： C07D213/75 , C07D231/40 , C07D237/20 , C07D239/42 , C07D241/20 , C07D249/04 , C07D261/14 , C07D271/07 , C07D275/03 , C07D277/18 , C07D277/46 , C07D277/60 , C07D277/82 , C07D285/08 , C07D285/10 , C07D285/135 , C07D401/12 , C07D405/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D513/04
摘要： Compounds represented by formula (I): as well as their pharmaceutically acceptable salts are disclosed. The compounds are useful as glucokinase activating agents for the treatment of diabetes and related conditions. Compositions and methods of treatment are also included.
摘要翻译：公开了由式（I）表示的化合物及其药学上可接受的盐。该化合物可用作糖尿病治疗和相关病症的葡糖激酶活化剂。还包括组合物和治疗方法。

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