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31. 发明申请

US20060033026A1 Near infrared chemical imaging microscope 失效
公开(公告)号：US20060033026A1
公开(公告)日：2006-02-16
申请号：US11256889
申请日：2005-10-24
申请人： Patrick Treado , Matthew Nelson , Scott Keitzer
发明人： Patrick Treado , Matthew Nelson , Scott Keitzer
IPC分类号： G01N21/35
CPC分类号： G01N21/359 , G01J3/2823 , G02B21/0016 , G02B21/06
摘要： A chemical imaging system is provided which uses a near infrared radiation microscope. The system includes an illumination source which illuminates an area of a sample using light in the near infrared radiation wavelength and light in the visible wavelength. A multitude of spatially resolved spectra of transmitted, reflected, emitted or scattered near infrared wavelength radiation light from the illuminated area of the sample is collected and a collimated beam is produced therefrom. A near infrared imaging spectrometer is provided for selecting a near infrared radiation image of the collimated beam. The filtered images are collected by a detector for further processing. The visible wavelength light from the illuminated area of the sample is simultaneously detected providing for the simultaneous visible and near infrared chemical imaging analysis of the sample. Two efficient means for performing three dimensional near infrared chemical imaging microscopy are provided.

32. 发明申请

US20060001871A1 Raman spectroscopic methods for component particle analysis 有权
标题翻译：拉曼光谱分析方法
公开(公告)号：US20060001871A1
公开(公告)日：2006-01-05
申请号：US11000778
申请日：2004-11-30
申请人： Matthew Nelson , Patrick Treado , Jason Attanucci
发明人： Matthew Nelson , Patrick Treado , Jason Attanucci
IPC分类号： G01J3/44 , G01N21/65
CPC分类号： G01N15/1475 , G01N21/65 , G01N2015/1493
摘要： The invention relates to methods of assessing one or more geometric properties of a particle of a substance using a Raman spectroscopic property of the substance. The method is useful, for example, for assessing particle sizes and size distributions in mixtures containing both particles of the substance and other materials.
摘要翻译：本发明涉及使用该物质的拉曼光谱性质评估物质颗粒的一种或多种几何性质的方法。该方法例如用于评估含有物质颗粒和其它材料的混合物的粒度和尺寸分布是有用的。

33. 发明申请

US20060001868A1 System and method for spectroscopy and imaging 审中-公开
标题翻译：用于光谱和成像的系统和方法
公开(公告)号：US20060001868A1
公开(公告)日：2006-01-05
申请号：US10879633
申请日：2004-06-30
申请人： Shona Stewart , Matthew Nelson , Joseph Demuth , Patrick Treado
发明人： Shona Stewart , Matthew Nelson , Joseph Demuth , Patrick Treado
IPC分类号： G01J3/44 , G01N21/65
CPC分类号： G01J3/44 , G01J3/0297 , G01N21/65
摘要： The disclosure relates to a substrate material for the improved detection, resolution and imaging of biological material for spectroscopic characterization by Raman of optical imaging spectroscopy. The substrate provides a uniform, optically flat, highly reflective surface which can be made hydrophobic to prevent spreading of the sample and facilitating its optical evaluation. Moreover, the substrate can be coated with a material that does not emit Raman scattered photons when exposed to said illuminating photons. The principles disclosed herein allow a low spectroscopic background particularly suitable for examining small samples or samples having low concentrations of the suspected component.
摘要翻译：本公开涉及用于通过光学成像光谱法的拉曼进行光谱表征的生物材料的改进的检测，分辨和成像的基底材料。衬底提供均匀的光学平坦的高反射表面，其可以被制成疏水性以防止样品的扩散并且便于其光学评估。此外，当暴露于所述照射光子时，衬底可以涂覆有不发射拉曼散射光子的材料。本文公开的原理允许低光谱背景特别适合于检查具有低浓度可疑成分的小样品或样品。

34. 发明授权

US08582089B2 System and method for combined raman, SWIR and LIBS detection 有权
标题翻译：组合拉曼，SWIR和LIBS检测的系统和方法
公开(公告)号：US08582089B2
公开(公告)日：2013-11-12
申请号：US12899119
申请日：2010-10-06
申请人： Matthew Nelson , Patrick Treado , Charles W Gardner, Jr.
发明人： Matthew Nelson , Patrick Treado , Charles W Gardner, Jr.
IPC分类号： G01N21/00
CPC分类号： G01J3/02 , G01J3/0221 , G01J3/0264 , G01J3/2823 , G01J3/36 , G01J3/44 , G01N21/359 , G01N21/65 , G01N21/718 , G01N33/227 , G01N2021/1738 , G01N2021/174 , G01N2021/1744
摘要： A system and method for the detection and identification of explosives and explosive residues using a combination of SWIR, Raman, and LIBS spectroscopy techniques, including imaging. A region of interest may be surveyed to identify a target area, wherein the target area comprises at least one unknown material. This surveying may be accomplished using visible imagery or SWIR imagery. The target area may be interrogated using Raman spectroscopy and LIBS spectroscopy to identify the unknown material. SWIR techniques may also be used to interrogate the target area. Fusion algorithms may also be applied to visible images, SWIR data sets, Raman data sets, and/or LIBS data sets.
摘要翻译：一种使用SWIR，拉曼和LIBS光谱技术组合检测和识别爆炸物和爆炸物残留物的系统和方法，包括成像。可以调查感兴趣的区域以识别目标区域，其中目标区域包括至少一种未知材料。可以使用可见图像或SWIR图像来完成此测量。可以使用拉曼光谱和LIBS光谱来询问目标区域以识别未知材料。也可以使用SWIR技术来询问目标区域。融合算法也可以应用于可见图像，SWIR数据集，拉曼数据集和/或LIBS数据集。

35. 发明申请

US20120062740A1 Hyperspectral imaging sensor for tracking moving targets 审中-公开
标题翻译：用于跟踪移动目标的高光谱成像传感器
公开(公告)号：US20120062740A1
公开(公告)日：2012-03-15
申请号：US13199977
申请日：2011-09-14
申请人： Patrick Treado , Matthew Nelson , Charles Gardner, JR.
发明人： Patrick Treado , Matthew Nelson , Charles Gardner, JR.
IPC分类号： H04N7/18
CPC分类号： G01J3/2823 , G01J3/0264 , G01J3/0289 , G01J3/0291 , G06T7/248 , G06T2207/10036 , G06T2207/30232
摘要： The present disclosure provides for a system and method for aerial detection, identification, and/or tracking of unknown ground targets. A system may comprise collection optics, a RGB detector, a SWIR MCF, a SWIR detector, and a sensor housing affixed to an aircraft. A method may comprise generating a RGB video image, a hyperspectral SWIR image, and combinations hereof. The RGB video image and the hyperspectral SWIR image may be analyzed to detect, identify, and/or track unknown targets. The RGB video image and the hyperspectral SWIR image may be generated simultaneously.
摘要翻译：本公开提供了一种用于未知地面目标的空中检测，识别和/或跟踪的系统和方法。系统可以包括收集光学器件，RGB检测器，SWIR MCF，SWIR检测器和固定到飞行器的传感器外壳。一种方法可以包括生成RGB视频图像，高光谱SWIR图像及其组合。可以分析RGB视频图像和超光谱SWIR图像以检测，识别和/或跟踪未知目标。可以同时生成RGB视频图像和超光谱SWIR图像。

36. 发明申请

US20120062697A1 Hyperspectral imaging sensor for tracking moving targets 审中-公开
公开(公告)号：US20120062697A1
公开(公告)日：2012-03-15
申请号：US13199981
申请日：2011-09-14
申请人： Patrick Treado , Matthew Nelson , Charles Gardner, JR.
发明人： Patrick Treado , Matthew Nelson , Charles Gardner, JR.
IPC分类号： H04N13/00
CPC分类号： H04N5/332 , G01S3/7864
摘要： The present disclosure provides for a system and method for aerial detection, identification, and/or tracking of unknown ground targets. A system may comprise collection optics, a RGB detector, a SWIR MCF, a SWIR detector, and a sensor housing affixed to an aircraft. A method may comprise generating a RGB video image, a hyperspectral SWIR image, and combinations hereof. The RGB video image and the hyperspectral SWIR image may be analyzed to detect, identify, and/or track unknown targets. The RGB video image and the hyperspectral SWIR image may be generated simultaneously.

37. 发明申请

US20110261351A1 SYSTEM AND METHOD FOR DETECTING EXPLOSIVES USING SWIR AND MWIR HYPERSPECTRAL IMAGING 审中-公开
标题翻译：使用SWIR和MWIR超分辨率成像检测爆炸物的系统和方法
公开(公告)号：US20110261351A1
公开(公告)日：2011-10-27
申请号：US13020944
申请日：2011-02-04
申请人： Patrick Treado , Charles W. Gardner, JR. , Matthew Nelson , Ryan Priore
发明人： Patrick Treado , Charles W. Gardner, JR. , Matthew Nelson , Ryan Priore
IPC分类号： G01N21/27 , G01N21/75
CPC分类号： G01J3/32 , G01J3/02 , G01J3/0218 , G01J3/0264 , G01J3/0289 , G01J3/36 , G01J3/4338 , G01J3/44 , G01N21/3563 , G01N21/359 , G01N21/39 , G01N33/0057
摘要： A system and method for detection of explosive agents using hyperspectral imaging. A system comprising an illumination source, a spectral encoding device, and at least one imaging detector configured for at least one of SWIR and MWIR hyperspectral imaging of a target comprising an unknown material. A method comprising illuminating a target comprising an unknown material, assessing interacted photons using a spectral encoding device, and detecting interacted photons using at least one of SWIR hyperspectral imaging and MWIR hyperspectral imaging. Algorithms and chemometric techniques may be applied to assess the MWIR hyperspectral image to identify the unknown material as comprising an explosive agent or a non-explosive agent. A video imaging device may also be configured to provide a video image of an area of interest, which may be assessed to identify a target for interrogation using SWIR and MWIR hyperspectral imaging.
摘要翻译：使用高光谱成像检测爆炸物的系统和方法。一种包括照明源，光谱编码装置和至少一个成像检测器的系统，该至少一个成像检测器被配置用于包括未知材料的靶的SWIR和MWIR高光谱成像中的至少一个。一种方法，包括照射包括未知材料的靶，使用光谱编码装置评估相互作用的光子，以及使用SWIR高光谱成像和MWIR高光谱成像中的至少一种来检测相互作用的光子。可以应用算法和化学计量技术来评估MWIR高光谱图像，以将未知材料识别为包括爆炸剂或非爆炸剂。视频成像设备还可以被配置为提供感兴趣区域的视频图像，其可以被评估以使用SWIR和MWIR高光谱成像识别用于询问的目标。

38. 发明申请

US20110242533A1 System and Method for Detecting Hazardous Agents Including Explosives 审中-公开
标题翻译：检测含有爆炸物的有害物质的系统和方法
公开(公告)号：US20110242533A1
公开(公告)日：2011-10-06
申请号：US13020935
申请日：2011-02-04
申请人： Patrick Treado , Charles W. Gardner, JR. , Matthew Nelson , Ryan Priore
发明人： Patrick Treado , Charles W. Gardner, JR. , Matthew Nelson , Ryan Priore
IPC分类号： G01J3/28
CPC分类号： G01J3/32 , G01J3/44 , G01N21/359 , G01N33/0057
摘要： A system and method for MWIR hyperspectral imaging to detect hazardous agents including explosive agents. A system comprising an illumination source, a tunable filter, and an imaging detector configured for MWIR hyperspectral imaging of a target comprising an unknown material. A method comprising illuminating a target comprising an unknown material, passing interacted photons through a tunable filter, and generating a MWIR hyperspectral image of the target. Algorithms and chemometric techniques may be applied to assess the MWIR hyperspectral image to identify the unknown material as comprising an explosive agent or a non-explosive agent. A video imaging device may also be configured to provide a video image of an area of interest, which may be assessed to identify a target for interrogation using MWIR hyperspectral imaging.
摘要翻译：用于MWIR高光谱成像检测危险物质（包括爆炸物质）的系统和方法。一种包括照明源，可调谐滤光器和被配置用于包含未知材料的靶的MWIR高光谱成像的成像检测器的系统。一种方法，包括照射包括未知材料的靶，通过可调滤波器传递相互作用的光子，以及生成目标的MWIR高光谱图像。可以应用算法和化学计量技术来评估MWIR高光谱图像，以将未知材料识别为包括爆炸剂或非爆炸剂。视频成像设备还可以被配置为提供感兴趣区域的视频图像，其可以被评估以使用MWIR高光谱成像识别用于询问的目标。

39. 发明申请

US20070263290A1 CHEMICAL IMAGING FIBERSCOPE 有权
标题翻译：化学成像FIBERSCOPE
公开(公告)号：US20070263290A1
公开(公告)日：2007-11-15
申请号：US11744797
申请日：2007-05-04
申请人： Patrick Treado , Matthew Nelson , Scott Keitzer , Ryan Smith
发明人： Patrick Treado , Matthew Nelson , Scott Keitzer , Ryan Smith
IPC分类号： G02B5/04 , G02B3/00 , G02B5/22
CPC分类号： G02B6/06 , A61B1/00165 , A61B1/043 , A61B1/063 , A61B1/0638 , A61B1/0646 , A61B1/07 , A61B5/0075 , A61B5/0084 , G01J3/02 , G01J3/0208 , G01J3/0218 , G01J3/0227 , G01J3/024 , G01J3/0256 , G01J3/0262 , G01J3/0286 , G01J3/44 , G01J2003/1213
摘要： A fiberscope device is disclosed which is suitable for video imaging, laser Raman spectroscopy and laser Raman spectroscopic (i.e. chemical) imaging. The fiberscope design minimizes fiber background interference arising from the laser delivery fiber optic and the coherent fiber optic light gathering bundle while maintaining high light throughput efficiency through the use of integrated spectral filters. In the fiberscope design, the laser delivery fiber optic is offset from the coherent fiber optic light gathering bundle. The laser delivery field is captured entirely by the light gathering field of view of the coherent fiber bundle. The fiberscope incorporates spectral filter optical elements that provide environmental insensitivity, particularly to temperature and moisture. The fiberscope is suited to the analysis of a wide range of condensed phase materials (solids and liquids), including the analysis of biological materials such as breast tissue lesions and arterial plaques, in such a manner to delineate abnormal from normal tissues.
摘要翻译：公开了适用于视频成像，激光拉曼光谱和激光拉曼光谱（即化学）成像的纤维内窥镜装置。纤维镜设计可以最大限度地减少激光传输光纤和相干光纤采集光束产生的光纤背景干扰，同时通过使用集成光谱滤波器保持高光通量效率。在纤维镜设计中，激光传输光纤与相干光纤聚光束偏移。激光输送场完全由相干光纤束的聚光场捕获。纤维镜包含光谱滤光器光学元件，其提供环境不敏感性，特别是对温度和湿度。纤维内窥镜适用于分析各种凝聚相材料（固体和液体），包括分析生物材料如乳房组织损伤和动脉斑块，以便从正常组织中描绘异常。

40. 发明申请

US20070145258A1 Method and apparatus for automated spectral calibration 审中-公开
标题翻译：用于自动光谱校准的方法和装置
公开(公告)号：US20070145258A1
公开(公告)日：2007-06-28
申请号：US11640197
申请日：2006-12-18
申请人： Matthew Nelson , Patrick Treado
发明人： Matthew Nelson , Patrick Treado
IPC分类号： G01D18/00
CPC分类号： G01J3/28 , A61B5/0059 , A61B2560/0223 , G01J2003/2866
摘要： The disclosure generally relates to a method and apparatus for automated spectral calibration of a spectroscopy device. In one embodiment, the disclosure relates to a method for simultaneous calibration and spectral imaging of a sample by: simultaneously illuminating the sample and a calibrant with a plurality of illuminating photons; receiving, at the spectrometer, a first plurality of photons collected from the sample and a second plurality of photons collected from the calibrant; forming a calibrant spectrum from the first plurality of collected photons and a sample spectrum from the second plurality of collected photons; comparing the calibrant spectrum with a reference spectrum of the calibrant to determine a wavelength-shift in the calibrant spectrum; applying the wavelength-shift to the sample spectrum to obtain a calibrated sample spectrum.
摘要翻译：本发明一般涉及一种用于光谱设备的自动光谱校准的方法和装置。在一个实施方案中，本公开涉及通过以下步骤同时校准和光谱成像的方法：同时用多个照明光子照射样品和校准物; 在光谱仪处接收从样品收集的第一组多个光子和从校准物收集的第二组多个光子; 从所述第一多个收集的光子形成校准谱，以及来自所述第二多个收集的光子的样品光谱; 将校准谱与校准物的参考光谱进行比较，以确定校准谱中的波长漂移; 将波长偏移应用于样本光谱以获得校准的样本光谱。

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