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31. 发明授权

US07989731B2 Method for processing materials with laser pulses having a large spectral bandwidth 有权
标题翻译：用具有大光谱带宽的激光脉冲处理材料的方法
公开(公告)号：US07989731B2
公开(公告)日：2011-08-02
申请号：US10565582
申请日：2004-07-20
申请人： Mark Bischoff , Martin Hacker , Roland Sauerbrey , Gregor Stobrawa , Wolfgang Ziegler
发明人： Mark Bischoff , Martin Hacker , Roland Sauerbrey , Gregor Stobrawa , Wolfgang Ziegler
IPC分类号： B23K26/06
CPC分类号： B23K26/06 , B23K26/064
摘要： A method and device for processing materials with laser pulses having a large spectral bandwidth and a device for carrying out said method. The aim of the invention is to create an easy, flexible method enabling universally applicable processing which can, however, be adapted to specific processing and methodological requirements. According to the invention, one or several spectral parameters of the laser pulses, i.e. the spectral amplitude and/or spectral phase and/or spectral polarization thereof, is/are specifically modified, preferably according to a measuring process variable, in order to process material or during the occurrence of said processing. The invention is used in order to process material with laser pulses having a large spectral bandwidth, particularly femto-second pulses and pico-second pulses.
摘要翻译：一种用于利用具有大光谱带宽的激光脉冲处理材料的方法和装置以及用于执行所述方法的装置。本发明的目的是创建一种容易，灵活的方法，使得普遍适用的处理可以适应特定的处理和方法要求。根据本发明，激光脉冲的一个或几个光谱参数，即其光谱幅度和/或光谱相位和/或其光谱偏振被优选地根据测量过程变量进行修改，以便处理材料或在所述处理的发生期间。本发明用于处理具有大光谱带宽的激光脉冲的材料，特别是毫微微秒脉冲和微微秒脉冲。

32. 发明申请

US20110181702A1 METHOD AND SYSTEM FOR GENERATING A REPRESENTATION OF AN OCT DATA SET 审中-公开
标题翻译：用于产生OCT数据集的表示的方法和系统
公开(公告)号：US20110181702A1
公开(公告)日：2011-07-28
申请号：US12844696
申请日：2010-07-27
申请人： Christoph Hauger , Martin Hacker
发明人： Christoph Hauger , Martin Hacker
IPC分类号： H04N13/02 , G06K9/00 , H04N15/00
CPC分类号： G01B9/02087 , A61B3/102 , A61B3/1225 , G01B9/0203 , G01B9/02091
摘要： A method of generating a representation of an OCT data set includes obtaining the OCT data set, representing a plurality of tuples, each of which comprises values of three spatial coordinates and a value of a scattering intensity, obtaining a color image data set representing a plurality of tuples, each of which comprises values of two spatial coordinates and a color value, and generating an image data set, representing a plurality of tuples, each of which comprises values of three spatial coordinates and a color value. Generating the image data set is performed depending on an analysis of the OCT data set and an analysis of the color image data set.
摘要翻译：一种产生OCT数据集的表示的方法包括获得表示多个元组的OCT数据集，每个元组包括三个空间坐标值和散射强度的值，获得表示多个的彩色图像数据集每个元组包括两个空间坐标和颜色值的值，并且生成表示多个元组的图像数据集，每个元组包括三个空间坐标和颜色值的值。根据OCT数据集的分析和彩色图像数据集的分析来执行图像数据集的生成。

33. 发明授权

US07805009B2 Method and apparatus for measuring motion of a subject using a series of partial images from an imaging system 有权
标题翻译：用于使用来自成像系统的一系列部分图像来测量对象的运动的方法和装置
公开(公告)号：US07805009B2
公开(公告)日：2010-09-28
申请号：US11389351
申请日：2006-03-24
申请人： Matthew J. Everett , Claus Flachenecker , Martin Hacker , Scott A. Meyer , Keith E. O'Hara , Rick A. Williams
发明人： Matthew J. Everett , Claus Flachenecker , Martin Hacker , Scott A. Meyer , Keith E. O'Hara , Rick A. Williams
IPC分类号： G06K9/68 , G06K9/00
CPC分类号： A61B3/102 , A61B3/113
摘要： A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.
摘要翻译：行扫描成像器用于确定被摄体的运动。将来自行扫描成像器的每行图像数据与参考图像进行比较。参考图像中匹配线的位置显示了被摄体的位移。可以基于每行图像数据来确定当前被摄体位移。所得到的位移信息可用于将其他光束正确地放置在被摄体上。该方法可以应用于跟踪人眼以便于用光束照射进行测量，成像或处理。

34. 发明申请

US20100214533A1 Spectrometer 有权
标题翻译：光谱仪
公开(公告)号：US20100214533A1
公开(公告)日：2010-08-26
申请号：US12680574
申请日：2008-09-24
申请人： Martin Hacker , Roland Bergner , Ralf Ebersbach , Klaus-Ditmar Voigt , Roland barth , Eberhard Hofmann , Peter Klopfleisch
发明人： Martin Hacker , Roland Bergner , Ralf Ebersbach , Klaus-Ditmar Voigt , Roland barth , Eberhard Hofmann , Peter Klopfleisch
IPC分类号： A61B3/14 , A61B3/10
CPC分类号： A61B3/1225 , A61B3/102 , A61B3/12 , G01J3/02 , G01J3/0289 , G01J3/453 , G01J3/4535
摘要： A spectrometer is described, especially for an optical coherence tomograph (1) for detecting parameters of the human eye, with said spectrometer having an input for measurement radiation to be analyzed, fanning the measurement radiation spectrally out along a direction in a fan and guiding it onto a detector that extends along the direction and comprises a plurality of detector pixels that are sensitive to the measurement radiation, with the spectrometer (2) having an adjusting element (5) which can be adjusted in a controlled manner to adjust the relative position of the fan and the detector (8), thereby optimizing the incidence position (F) of the fan on the detector (8), in which it is provided that the detector (8) has at least two superimposed, adjacent pixel lines, and a control device (9) is provided which reads out the superimposed pixels of a plurality of pixel lines in a combined manner for a spectral analysis of the measurement radiation in a pixel binning and evaluates signal differences between superimposed pixels to control the adjusting element (5) and to center the incidence position of the fan at a right angle to the direction of the pixel lines.
摘要翻译：描述了一种光谱仪，特别是对于用于检测人眼参数的光学相干断层摄影机（1），其中所述光谱仪具有用于待分析的测量辐射的输入，沿着风扇中的方向光谱地扫射测量辐射并引导它到达沿着该方向延伸的检测器并且包括对测量辐射敏感的多个检测器像素，其中光谱仪（2）具有调节元件（5），该调节元件可以受控的方式调节以调整相对位置风扇和检测器（8），从而优化检测器（8）上的风扇的入射位置（F），其中设置检测器（8）具有至少两个叠加的相邻像素线，以及提供控制装置（9），其以组合的方式读出多个像素线的叠加像素，用于对像素分档中的测量辐射进行光谱分析，并评估符号叠加像素之间的差异来控制调节元件（5）并使风扇的入射位置与像素线的方向成直角。

35. 发明授权

US07388672B2 High efficiency balanced detection interferometer 有权
标题翻译：高效平衡检测干涉仪
公开(公告)号：US07388672B2
公开(公告)日：2008-06-17
申请号：US11264871
申请日：2005-11-02
申请人： Yan Zhou , Matthew J. Everett , Martin Hacker
发明人： Yan Zhou , Matthew J. Everett , Martin Hacker
IPC分类号： G01B9/02
CPC分类号： G01B9/02091 , G01B2290/40
摘要： An interferometer configured for use in optical coherence domain (OCT) reflectometry systems is disclosed. In the preferred embodiments, efficient routing of light and a balanced detection arrangement provide a high signal to noise ratio. In a first set of embodiments, a 3×3 coupler is used to split light along separate sample and reference paths and also for combining light returning from those paths and supplying the interfered collected light to the detection system. In an alternate set of embodiments, a pair of cascaded 2×2 couplers provides a similar function. The interferometer can be used with various OCT modalities including time-domain and frequency domain approaches.
摘要翻译：公开了一种配置用于光学相干域（OCT）反射系统的干涉仪。在优选实施例中，光的有效路由和平衡检测装置提供高的信噪比。在第一组实施例中，使用3x3耦合器沿独立的采样和参考路径分离光，并且还用于组合从那些路径返回的光并将受干扰的收集的光提供给检测系统。在另一组实施例中，一对级联的2x2耦合器提供类似的功能。干涉仪可以与各种OCT模式一起使用，包括时域和频域方法。

36. 发明申请

US20060171503A1 Method to suppress artifacts in frequency-domain optical coherence tomography 有权
标题翻译：抑制频域光学相干断层扫描中伪像的方法
公开(公告)号：US20060171503A1
公开(公告)日：2006-08-03
申请号：US11334964
申请日：2006-01-19
申请人： Keith O'Hara , Martin Hacker
发明人： Keith O'Hara , Martin Hacker
IPC分类号： H05G1/60
CPC分类号： A61B5/0066 , A61B5/0073 , A61B5/7257 , G01B9/0201 , G01B9/02058 , G01B9/02078 , G01B9/02083 , G01B9/02091
摘要： One embodiment of the present invention is a method for suppressing artifacts in frequency-domain OCT images, which method includes (a) providing sample and reference paths with a significant difference in their chromatic dispersion (b) correcting for the effects of the mismatch in chromatic dispersion, for the purpose of making artifacts in the OCT image readily distinguishable from the desired image.
摘要翻译：本发明的一个实施例是一种用于抑制频域OCT图像中的伪影的方法，该方法包括（a）提供其色散中显着差异的样本和参考路径（b）校正色差中的不匹配的影响分散体，用于使OCT图像中的人造物与期望的图像容易地区分开。

37. 发明授权

US08801184B2 System for the improved imaging of eye structures 有权
标题翻译：用于改善眼结构成像的系统
公开(公告)号：US08801184B2
公开(公告)日：2014-08-12
申请号：US13696030
申请日：2011-04-23
申请人： Martin Hacker , Rudolf Murai von Bünau , Burkhard Wagner
发明人： Martin Hacker , Rudolf Murai von Bünau , Burkhard Wagner
IPC分类号： A61B3/14 , A61B3/00
CPC分类号： A61B3/102 , A61B3/107 , A61B5/0066 , G01N21/4795 , G01N2021/1787
摘要： A system for the improved imaging of eye structures based on optical coherence tomography. The system includes an interferometric measuring arrangement, which has an optical element arranged in the measurement arm or reference arm for influencing the polarization state of the light before the light is interferometrically superimposed, a scanning unit arranged in the measurement arm for implementing OCT scans, a detector for recording the produced interference pattern, and an evaluating and documenting unit. At least two different polarization states of the light are produced. The interference patterns produced in the interferometric measuring arrangement are recorded and forwarded to the evaluating and documenting unit which reconstructs OCT scans from the transmitted interference patterns, combines the OCT scans, and presents and/or stores the resulting OCT signals. The system can be used for pachymetry in addition to the pre- and post-operative imaging for analysis and measurement.
摘要翻译：一种基于光学相干断层扫描的改善眼结构成像的系统。该系统包括干涉测量装置，其具有布置在测量臂或参考臂中的光学元件，用于在光被干涉地叠加之前影响光的偏振状态;布置在测量臂中用于实现OCT扫描的扫描单元，用于记录产生的干涉图案的检测器，以及评估和记录单元。产生光的至少两种不同的偏振态。在干涉测量装置中产生的干涉图案被记录并转发给评估和记录单元，其从发射的干涉图案重建OCT扫描，组合OCT扫描，并呈现和/或存储所得到的OCT信号。除了用于分析和测量的术前和术后成像，该系统可用于深度测量。

38. 发明授权

US08740380B2 Article for use in an OCT-method and intraocular lens 有权
标题翻译：用于OCT方法和眼内镜的文章
公开(公告)号：US08740380B2
公开(公告)日：2014-06-03
申请号：US12858216
申请日：2010-08-17
申请人： Marco Wilzbach , Martin Hacker , Christoph Hauger
发明人： Marco Wilzbach , Martin Hacker , Christoph Hauger
IPC分类号： A61B3/00 , A61B3/14 , A61F2/16
CPC分类号： A61B3/102 , A61B5/0066 , A61B17/30 , A61B90/30 , A61F2/16 , A61F2/1613 , A61F2250/0096 , B29D11/023 , B82Y20/00 , G01B9/02091 , G02B5/08 , G02B5/22
摘要： An article for use in an OCT method, the article comprising a solid substrate and nanoparticles dispersed in or on the substrate in at least one light transmissive portion of the article such that the nanoparticles result in an increased extinction of the light transmissive portion along a transmission direction of the light transmissive portion compared to the substrate being free of nanoparticles. The extinction of the light transmissive portion along the transmission direction is less than 6, wherein the extinction is defined as a negative decadic logarithm of a ratio of an intensity of light which is transmitted through the light transmissive portion to an intensity of light which is incident on the light transmissive portion, wherein the light is in at least one of a visible and a near infrared wavelength range.
摘要翻译：一种用于OCT方法的制品，所述制品包含固体基质和纳米颗粒，其分散在所述制品的至少一个透光部分中或所述基底中或基底上，使得所述纳米颗粒导致所述透光部分沿着透射的消光增加光透射部分的方向与衬底相比没有纳米颗粒。沿透射方向的光透射部分的消光小于6，其中消光被定义为通过透光部分透射的光的强度与入射光的强度之比的负十进制对数在所述光透射部分上，其中所述光处于可见光和近红外波长范围中的至少一个。

39. 发明授权

US08717576B2 Short coherence interferometer 有权
标题翻译：短相干干涉仪
公开(公告)号：US08717576B2
公开(公告)日：2014-05-06
申请号：US12680722
申请日：2008-09-26
申请人： Martin Hacker
发明人： Martin Hacker
IPC分类号： G01B9/02
CPC分类号： G01B9/02028 , A61B3/1005 , A61B3/102 , A61B3/113 , G01B9/02021 , G01B9/02035 , G01B9/02081 , G01B9/02091 , G01B2290/45 , G01B2290/70 , G01N21/4795 , G01N2021/1787
摘要： A short coherence interferometer apparatus for measuring multiple axially spaced regions of a specimen, in particular the eye, which has at least one measuring beam path, through which multiple individual measuring beams are incident on the specimen, and one reference beam path, through which a reference beam runs, with which the individual measuring beams are superimposed and brought into interference. The individual measuring beams are axially offset to one another upon incidence on the specimen by an amount which is adapted to the axial spacing. The interferometer apparatus superimposes each individual measuring beam with the reference beam in an interfering manner and conducts it to a detector associated with the particular individual measuring beam. The individual measuring beams are combined into a mixture in which they have varying phasing in the superposition with the reference beam.
摘要翻译：一种用于测量样本，特别是眼睛的多个轴向间隔的区域的短相干干涉仪装置，其具有至少一个测量光束路径，多个单独的测量光束通过该光束路径入射在样本上，以及一个参考光束路径，参考光束运行，各个测量光束通过它们叠加并引起干扰。当在试样上入射适当于轴向间距的量时，各个测量光轴彼此轴向偏移。干涉仪装置以干扰的方式将每个单独的测量光束与参考光束重叠，并将其传导到与特定的各个测量光束相关联的检测器。单独的测量光束被组合成混合物，在该混合物中它们与参考光束叠加时具有变化的相位。

40. 发明授权

US08690330B2 Device for swept-source optical coherence domain reflectometry 有权
标题翻译：扫频源光学相干域反射测量装置
公开(公告)号：US08690330B2
公开(公告)日：2014-04-08
申请号：US13140752
申请日：2009-12-21
申请人： Martin Hacker , Ralf Ebersbach , Thomas Pabst , Ulf Peterlein , Gerard Antkowiak , Roland Bergner , Ingo Koschmieder
发明人： Martin Hacker , Ralf Ebersbach , Thomas Pabst , Ulf Peterlein , Gerard Antkowiak , Roland Bergner , Ingo Koschmieder
IPC分类号： A61B3/10
CPC分类号： A61B3/1005 , A61B3/102 , G01B9/02004 , G01B9/0203 , G01B9/02067 , G01B9/02069 , G01B9/02091 , G01B2290/45 , G01N21/4795
摘要： A device for swept-source optical coherence domain reflectometry (SS OCDR) on moveable samples, particularly human eyes, for obtaining A-scans, having a measuring range according to the sample length and having a laser light source which can be adjusted by a main wave number k0 and at least one receiver for the light dissipated from the sample, wherein the sample is illuminated on the sample surface by a measurement beam having a diameter D by way of a coupling device. The light source has a spectral line width of δk
摘要翻译：一种用于扫描源光学相干畴反射测量（SS OCDR）的装置，用于可移动的样品，特别是人眼，用于获得A扫描，具有根据样品长度的测量范围，并具有可由主体调节的激光光源波数k0和用于从样品消散的光的至少一个接收器，其中样品通过耦合装置具有直径D的测量光束照射在样品表面上。光源的谱线宽度δk<168m-1，光源的调整在τ<44s /（D * k0）内进行。

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