专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明申请

WO2006030205A2 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2006030205A2
公开(公告)日：2006-03-23
申请号：PCT/GB2005003543
申请日：2005-09-14
申请人： MICROMASS LTD , WILDGOOSE JASON LEE , PRINGLE STEVEN DEREK , GILES KEVIN , BATEMAN ROBERT HAROLD
发明人： WILDGOOSE JASON LEE , PRINGLE STEVEN DEREK , GILES KEVIN , BATEMAN ROBERT HAROLD
IPC分类号： H01J49/40
CPC分类号： H01J49/005
摘要： A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (3) arranged upstream of a collision or fragmentation cell (5). Ions are separated according to their ion mobility within the ion mobility spectrometer or separator (3). The kinetic energy of the ions exiting the ion mobility spectrometer or separator (3) is increased substantially linearly with time in order to optimise the fragmentation energy of ions as they enter the collision or fragmentation cell (5).
摘要翻译：公开了一种质谱仪，其包括设置在碰撞或破碎电池（5）的上游的离子迁移谱仪或分离器（3）。离子在离子迁移谱仪或分离器（3）内根据其离子迁移率分离。离子离子迁移谱仪或分离器（3）离子的动能随时间呈线性增加，以优化离子进入碰撞或破碎电池（5）时的碎裂能。

32. 发明专利

CA2628924C MASS SPECTROMETER 未知
公开(公告)号：CA2628924C
公开(公告)日：2017-09-05
申请号：CA2628924
申请日：2006-11-23
申请人： MICROMASS LTD
发明人： BATEMAN ROBERT HAROLD
IPC分类号： H01J49/42
摘要： A method of mass spectrometry is disclosed wherein an Electron Capture Dissociation, Electron Transfer Dissociation or Surface Induced Dissociation fragmentation device is repeatedly switched between a high fragmentation or reaction mode and a low fragmentation or reaction mode. Parent ions from a first sample are passed through the device and parent ion mass spectra and fragmentation ion mass spectra are obtained. Parent ions from a second sample are then passed through the device and a second set of parent ion mass spectra and fragmentation ion mass spectra are obtained. The mass spectra are then compared and if either certain parent ions or certain fragmentation ions in the two samples are expressed differently then further analysis is performed to seek to identify the ions which are expressed differently in the two different samples.

33. 发明专利

CA2588804C MASS SPECTROMETER 未知
公开(公告)号：CA2588804C
公开(公告)日：2017-05-30
申请号：CA2588804
申请日：2005-12-08
申请人： MICROMASS LTD
发明人： BATEMAN ROBERT HAROLD , GILES KEVIN , PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE , BROWN JEFFREY MARK
IPC分类号： H01J49/04 , H01J49/42
摘要： A mass spectrometer is disclosed comprising a mass selective ion trap or mass analyser (4) arranged upstream of an ion guide (6). Ions are scanned out of the mass selective ion trap or mass analyser (4) and are received in one or more axial potential wells created or formed within the ion guide (6). One or more transient DC voltages or potentials are preferably applied to the ion guide (6) in order to create a plurality of axial potential wells which are translated along the length of the ion guide (6). Ions are released in packets from the exit of the ion guide (6) and are orthogonally accelerated into a drift or flight region of an orthogonal acceleration Time of Flight mass analyser (13) with a relatively high duty cycle.

34. 发明专利

CA2730782C ION SOURCE WITH DEVICE FOR OXIDISING A SAMPLE 未知
公开(公告)号：CA2730782C
公开(公告)日：2017-05-09
申请号：CA2730782
申请日：2009-07-16
申请人： MICROMASS LTD
发明人： BATEMAN ROBERT HAROLD
IPC分类号： H01J37/00 , G01N31/12 , H01J49/14
摘要： An ion source is disclosed wherein a sample is introduced into the sample chamber (1) of the ion source in the gas phase via a sample introduction capillary tube (2). The sample is directed onto a heated surface (6) coated with an oxidising reagent such as copper oxide. Carbon in the sample is oxidised to form carbon dioxide. The resulting carbon dioxide molecules are then ionised by electron impact ionisation with an electron beam (3) and the resulting ions are passed to a mass analyser for mass analysis.

35. 发明专利

CA2742437C MASS SPECTROMETER 未知
公开(公告)号：CA2742437C
公开(公告)日：2016-09-27
申请号：CA2742437
申请日：2003-06-25
申请人： MICROMASS LTD
发明人： GILES KEVIN , HOYES JOHN BRIAN , PRINGLE STEVE , WILDGOOSE JASON LEE , BATEMAN ROBERT HAROLD
IPC分类号： G01N27/62 , H01J49/26
摘要： An ion mobility separator, and a method of ion mobility separation, where ions separate within the ion mobility separator according to their ion mobility and assume different essentially static or equilibrium axial positions along the length of the ion mobility separator.

36. 发明专利

CA2585565C MASS SPECTROMETER 未知
公开(公告)号：CA2585565C
公开(公告)日：2016-09-06
申请号：CA2585565
申请日：2005-11-03
申请人： MICROMASS LTD
发明人： BATEMAN ROBERT HAROLD , GILES KEVIN , PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE
IPC分类号： H01J49/04 , H01J49/06 , H01J49/40 , H01J49/42
摘要： A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (4) and an ion guide (6) arranged downstream of the ion mobility spectrometer or separator (4). A plurality of axial potential wells are created in the ion guide (6) so that ions received from the ion mobility spectrometer or separator (4) become confined in separate axial potential wells. The potential wells maintain the fidelity and/or composition of ions received from the ion mobility spectrometer or separator (4). The potential wells are translated along the length of the ion guide (6).

37. 发明专利

CA2628922C MASS SPECTROMETER 未知
公开(公告)号：CA2628922C
公开(公告)日：2016-01-26
申请号：CA2628922
申请日：2006-11-10
申请人： MICROMASS LTD
发明人： BATEMAN ROBERT HAROLD , GILES KEVIN , PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE
IPC分类号： H01J49/26 , G01N27/62 , H01J49/42
摘要： A mass spectrometer is disclosed comprising a first ion trap or ion guide (2) , a single ion mobility spectrometer or separator stage (3) and a second ion trap or ion guide (4) arranged downstream of the ion mobility spectrometer or separator (3). In a mode of operation ions from the second ion trap or ion guide (4) are passed from the second ion trap or ion guide back upstream to the ion mobility spectrometer or separator (3).

38. 发明专利

CA2651362C MASS SPECTROMETER 未知
公开(公告)号：CA2651362C
公开(公告)日：2013-02-26
申请号：CA2651362
申请日：2007-06-01
申请人： MICROMASS LTD
发明人： BATEMAN ROBERT HAROLD , BROWN JEFFREY MARK , GREEN MARTIN , WILDGOOSE JASON LEE , GILBERT ANTHONY JAMES , PRINGLE STEVEN DEREK
IPC分类号： H01J49/02
摘要： A mass spectrometer is disclosed comprising a Time of Flight mass analyser comprising an ion detector comprising an Analogue to Digital Converter. Signals from the Analogue to Digital Converter are digitised and the arrival time and intensity of ions are determined. The arrival time T0 and intensity S0 of each ion arrival event is converted into two separate intensities S(n),S(n+i) which are stored in neighbouring time bins T(n), T(n+1).

39. 发明专利

GB2462175B Ion source with device for oxidising a sample 未知
公开(公告)号：GB2462175B
公开(公告)日：2013-02-13
申请号：GB0912433
申请日：2009-07-16
申请人： MICROMASS LTD
发明人： BATEMAN ROBERT HAROLD
IPC分类号： H01J49/14 , H01J49/10
摘要： An ion source is disclosed wherein a sample is introduced into the sample chamber of the ion source in the gas phase via a sample introduction capillary tube. The sample is directed onto a heated surface coated with an oxidizing reagent such as copper oxide. Carbon in the sample is oxidized to form carbon dioxide. The resulting carbon dioxide molecules are then ionised by electron impact ionization with an electron beam and the resulting ions are passed to a mass analyzer for mass analysis.

40. 发明专利

CA2628926C MASS SPECTROMETER 未知
公开(公告)号：CA2628926C
公开(公告)日：2013-01-08
申请号：CA2628926
申请日：2006-11-23
申请人： MICROMASS LTD
发明人： BATEMAN ROBERT HAROLD
IPC分类号： H01J49/42
摘要： A method is disclosed of identifying parent ions by matching daughter ions found to be produced at substantially the same time that the parent ions elute from a mixture. Ions emitted from an ion source (1) are transmitted to a fragmentation device (4) comprising an Electron Capture Dissociation, an Electron Transfer Dissociation or a Surface Induced Dissociation fragmentation device. The fragmentation device (4) is alternately and repeatedly switched between a first mode wherein the ions are substantially fragmented to produce daughter ions and a second mode wherein the ions are not substantially fragmented. Mass spectra are taken in both modes. At the end of an experimental run parent and daughter ions are recognised by comparing the mass spectra obtained in the two different modes. Daughter ions are matched to particular parent ions on the basis of the closeness of fit of their elution times, and this enables parent ions then to be identified.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式