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31. 发明专利

AU1714499A Four-chamber pacing system for optimizing cardiac output 未知
公开(公告)号：AU1714499A
公开(公告)日：1999-07-05
申请号：AU1714499
申请日：1998-12-07
申请人： MEDTRONIC INC
发明人： BAKELS ARNOLDUS , LEINDERS ROBERT , ROOS CUBUS DE
IPC分类号： A61N1/362 , A61N1/365 , A61N1/368
摘要： A pacing system and method for providing multiple chamber pacing of a patient's heart, and in particular, pacing programmed for treatment of various forms of heart failure. The system utilizes impedance sensing for determining optimum pacing parameters, e.g., for pacing the left ventricle so that left heart output is maximized. The impedance sensing also is used for determination of arrhythmias or progression of heart failure. Impedance sensing is provided for between selected pairs of the four chambers, to enable optimizing of information for control and diagnosis. In a preferred embodiment of the invention, impedance measurements are obtained for determining the timing of right heart valve closure or right ventricular contractions, and the timing of delivery of left ventricular pace pulses is adjusted so as to optimally synchronize left ventricular pacing with the right ventricular contractions. Impedance sensing in the left heart also provides timing of mechanical contraction, and the pacemaker controls pacing to maintain bi-ventricular mechanical synchronization adjusted for maximum cardiac output.

32. 发明专利

FR2559068B1 未知
公开(公告)号：FR2559068B1
公开(公告)日：1990-01-26
申请号：FR8501446
申请日：1985-02-01
申请人： MEDTRONIC INC
发明人： LEINDERS ROBERT
IPC分类号： A61N1/39 , A61N1/08

33. 发明专利

FR2559068A1 Implanted defibrillator with protection circuit 未知
公开(公告)号：FR2559068A1
公开(公告)日：1985-08-09
申请号：FR8501446
申请日：1985-02-01
申请人： MEDTRONIC INC
发明人： LEINDERS ROBERT
IPC分类号： A61N1/39 , A61N1/08
摘要： A protection circuit is included in the interface that forms the input to the instrument. It links the two inputs from the heart electrodes to the QRS-detector during the period of the cardioversion energy pulse generated by the pacemaker circuit. Protection is effected by series opposed zener diodes and the break down voltage, plus or minus 500V of a triac which is edge triggered by the RC-network.

34. 发明专利

DE3503854A1 Implantable medical instrument 未知
公开(公告)号：DE3503854A1
公开(公告)日：1985-08-08
申请号：DE3503854
申请日：1985-02-05
申请人： MEDTRONIC INC
发明人： LEINDERS ROBERT
IPC分类号： A61N1/39 , A61N1/365 , H02H7/20
摘要： Implantable medical instrument for electrical termination of arrhythmia states of the heart, having terminals which can be coupled to an electrode arrangement in contact with the heart, a current source, a detector device, coupled to at least one of the terminals, on determining an arrhythmia of the heart and for supplying a trigger signal on the basis of such a determination, a cardioversion pulse generator circuit for providing a cardioversion energy pulse on the basis of a trigger signal, and an interface arrangement for applying the cardioversion energy pulse to at least one of the terminals. The interface arrangement has a protective circuit which, in response to the generation of a cardioversion energy pulse, in the event of the application of the pulse between a first terminal, which can be coupled to a first electrode arrangement in contact with a first region of the heart, and a third terminal which can be coupled to an electrode arrangement in contact with a third region of the heart, connects the third terminal electrically in series to a second terminal, which can be coupled to a second electrode arrangement in contact with a second region of the heart and which, just like the third terminal, is coupled to the detector device (Fig. 1). … …

35. 发明专利

DE10117241B4 Vorrichtung zur Ermöglichung einer unmittelbaren Abfrage von Informationen und einer Identifikation von einer implantierbaren medizinischen Vorrichtung mit einer verbrauchten Energiequelle 未知
公开(公告)号：DE10117241B4
公开(公告)日：2012-11-08
申请号：DE10117241
申请日：2001-04-06
申请人： MEDTRONIC INC
发明人： TORGERSON NATHAN A , JENSEN STEVEN L , LEINDERS ROBERT , GREVIOUS JOHN J , FORSBERG JOHN W , MCMULLEN RAYMOND F
IPC分类号： A61N1/378 , A61F2/02 , A61M5/142 , A61N1/08 , A61N1/372
摘要： Implantierbare medizinische Vorrichtung mit: einer Antenne zum Empfang und zur Übertragung von Telemetriesignalen; einer Gleichrichterschaltung, die an die Antenne angeschlossen ist; einer elektrischen Hauptenergiequelle, um die implantierbare medizinische Vorrichtung mit Energie zu versorgen; einer zusätzlichen, an die Gleichrichterschaltung angeschlossenen Energiequelle mit einer Energiespeichervorrichtung zum Speichern von genügend Energie, um Strom zur Erregung der implantierbaren medizinischen Vorrichtung zu liefern, wobei die Energie von einer externen Quelle über Telemetriesignale empfangen wird; einem Komparator, um Spannungshöhen der Hauptenergiequelle und der zusätzlichen Energiequelle zu vergleichen und ein Signal auszugeben, das anzeigt, welche Energiequelle stärker ist; und einem Spannungsumsteller, der dafür bestimmt ist, das Ausgabesignal des Komparators zu empfangen, wobei der Spannungsumsteller ermöglicht, dass basierend auf dem von dem Komparator empfangenen Signal Strom entweder von der Hauptenergiequelle oder der zusätzlichen Energiequelle fließt, um die implantierbare medizinische Vorrichtung mit Energie zu versorgen, wodurch eine Kommunikation mit einem externen Programmierer über Telemetrieabfrage von Identifikationen...

36. 发明专利

DE60321905D1 未知
公开(公告)号：DE60321905D1
公开(公告)日：2008-08-14
申请号：DE60321905
申请日：2003-03-26
申请人： MEDTRONIC INC
发明人： LEINDERS ROBERT , TORGERSON NATHAN A , STEIN MARC T , GOBLISH TODD P , HEATHERSHAW TODD , RODRIQUEZ JOHN D
IPC分类号： A61N1/05 , A61N1/36 , A61N1/372
摘要： In the embodiment of the invention, apparatus and method provide flexibility in generating a stimulation waveform to an electrode of an Implantable Neurological Stimulator (INS). The embodiment provides a time delay interval between a first stimulation pulse and a recharging of the apparatus, in which the time delay interval is adjustable. The embodiment utilizes apparatus comprising a waveform controller and a waveform generator that is controlled by the waveform controller. With a variation of the embodiment, the apparatus utilizes passive recharging. In another variation of the embodiment, the apparatus utilizes a second stimulation to balance an accumulated charge. In another embodiment of the invention, a clinician is able to adjust the time delay interval through a telemetry channel. The waveform controller receives information about the time delay interval, and the waveform control instructs the waveform generator to adjust the time delay interval.

37. 发明专利

AT399578T 未知
公开(公告)号：AT399578T
公开(公告)日：2008-07-15
申请号：AT03716855
申请日：2003-03-26
申请人： MEDTRONIC INC
发明人： LEINDERS ROBERT , TORGERSON NATHAN A , STEIN MARC T , GOBLISH TODD P , HEATHERSHAW TODD , RODRIQUEZ JOHN D
IPC分类号： A61N1/05 , A61N1/36 , A61N1/372
摘要： In the embodiment of the invention, apparatus and method provide flexibility in generating a stimulation waveform to an electrode of an Implantable Neurological Stimulator (INS). The embodiment provides a time delay interval between a first stimulation pulse and a recharging of the apparatus, in which the time delay interval is adjustable. The embodiment utilizes apparatus comprising a waveform controller and a waveform generator that is controlled by the waveform controller. With a variation of the embodiment, the apparatus utilizes passive recharging. In another variation of the embodiment, the apparatus utilizes a second stimulation to balance an accumulated charge. In another embodiment of the invention, a clinician is able to adjust the time delay interval through a telemetry channel. The waveform controller receives information about the time delay interval, and the waveform control instructs the waveform generator to adjust the time delay interval.

38. 发明专利

DE69836990D1 未知
公开(公告)号：DE69836990D1
公开(公告)日：2007-03-15
申请号：DE69836990
申请日：1998-12-07
申请人： MEDTRONIC INC
发明人： BAKELS ARNOLDUS , LEINDERS ROBERT , DE ROOS COBUS
IPC分类号： A61N1/368 , A61N1/362 , A61N1/365
摘要： A pacing system and method for providing multiple chamber pacing of a patient's heart, and in particular, pacing programmed for treatment of various forms of heart failure. The system utilizes impedance sensing for determining optimum pacing parameters, e.g., for pacing the left ventricle so that left heart output is maximized. The impedance sensing also is used for determination of arrhythmias or progression of heart failure. Impedance sensing is provided for between selected pairs of the four chambers, to enable optimizing of information for control and diagnosis. In a preferred embodiment of the invention, impedance measurements are obtained for determining the timing of right heart valve closure or right ventricular contractions, and the timing of delivery of left ventricular pace pulses is adjusted so as to optimally synchronize left ventricular pacing with the right ventricular contractions. Impedance sensing in the left heart also provides timing of mechanical contraction, and the pacemaker controls pacing to maintain bi-ventricular mechanical synchronization adjusted for maximum cardiac output.

39. 发明专利

AU2003231011A1 INDEPENDENT THERAPY PROGRAMS IN AN IMPLANTABLE MEDICAL DEVICE 未知
公开(公告)号：AU2003231011A1
公开(公告)日：2003-11-10
申请号：AU2003231011
申请日：2003-04-17
申请人： MEDTRONIC INC
发明人： LEINDERS ROBERT , TORGERSON NATHAN A , STEIN MARC T , GOBLISH TODD P , HEATHERSHAW TODD P , RODRIQUEZ JOHN D
IPC分类号： A61N1/05 , A61N1/34
摘要： Apparatus and method for independently delivering a plurality of therapy programs in an implantable medical device. A therapy controller configures the device to generate independent pulse trains associated with a plurality of therapy programs and dynamically configures the electrodes to deliver the independent pulse trains to the patient. Once configured, the implantable medical device delivers the plurality of therapy programs to the patient wherein the therapy programs may overlap in time.

40. 发明专利

AU2003220507A1 PROGRAMMABLE WAVEFORM PULSES FOR AN IMPLANTABLE MEDICAL DEVICE 未知
公开(公告)号：AU2003220507A1
公开(公告)日：2003-11-10
申请号：AU2003220507
申请日：2003-03-25
申请人： MEDTRONIC INC
发明人： GOBLISH TODD P , LEINDERS ROBERT , STEIN MARC T , RODRIQUEZ JOHN D , HEATHERSHAW TODD , TORGERSON NATHAN A
IPC分类号： A61N1/05 , A61N1/36
摘要： Apparatus and method provide flexibility in generating a stimulation waveform to an electrode of an Implantable Neuro Stimulator (INS). The stimulation waveform is synthesized for each rate period interval. Each rate period interval is partitioned into time intervals, during which stimulation pulses, recharging, and time duration delays may be induced. With the embodiment of the invention, a second stimulation pulse, having different electrical characteristics than a first stimulation pulse, may be generated during the rate period interval. An embodiment utilizes apparatus comprising a waveform controller and a waveform generator that are controlled by the waveform controller. The waveform controller uses waveform parameters to instruct the waveform generator to form stimulation pulses. Any of the components may be adjusted or deleted in the generation of the stimulation waveform. The embodiment enables any of the associated waveform parameters to be updated at the waveform controller in order to alter the stimulation waveform.

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