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31. 发明授权

US06620193B1 Method of deploying a stent in a body lumen 有权
标题翻译：在体腔中部署支架的方法
公开(公告)号：US06620193B1
公开(公告)日：2003-09-16
申请号：US09323783
申请日：1999-06-01
申请人： Lilip Lau , William M. Hartigan , John J. Frantzen
发明人： Lilip Lau , William M. Hartigan , John J. Frantzen
IPC分类号： A61F206
CPC分类号： A61F2/86 , A61F2/848 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2210/0019 , A61M2025/1081 , C23F1/02 , C23F1/04 , Y10S623/901 , Y10S623/903 , Y10S623/921 , Y10T29/49995
摘要： The invention is directed to an expandable stent for implantation in a body lumen, such as an artery, and a method for making it from a single length of tubing. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common axis and interconnected by one or more interconnective elements. The individual radially expandable cylindrical elements consist of ribbon-like material disposed in an undulating pattern. Portions of the expanded stent project outwardly into engagement with the vessel wall to more securely attach the stent.
摘要翻译：本发明涉及用于植入体腔（例如动脉）中的可扩张支架，以及用于从单一管道制造它的方法。支架由多个径向可扩张的圆柱形元件组成，其大致在公共轴线上对准并且由一个或多个互连元件相互连接。各个可径向扩张的圆柱形元件由以波浪形图案布置的带状材料组成。扩张的支架的一部分向外突出地与血管壁接合，以更牢固地附接支架。

32. 发明授权

US06613072B2 Procedures for introducing stents and stent-grafts 失效
标题翻译：引入支架和支架移植物的程序
公开(公告)号：US06613072B2
公开(公告)日：2003-09-02
申请号：US08896373
申请日：1997-07-18
申请人： Lilip Lau , Charles T. Maroney , William M. Hartigan , Sharon Lam
发明人： Lilip Lau , Charles T. Maroney , William M. Hartigan , Sharon Lam
IPC分类号： A61F206
CPC分类号： A61F2/88 , A61F2/07 , A61F2/844 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/92 , A61F2/95 , A61F2002/061 , A61F2002/072 , A61F2002/075 , A61F2002/3008 , A61F2002/30093 , A61F2002/30462 , A61F2002/828 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2002/9511 , A61F2002/9665 , A61F2210/0019 , A61F2220/0075 , A61F2230/0039 , A61F2230/0041 , A61F2230/006 , A61F2230/0078 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00137 , A61F2310/00149
摘要： This invention is a medical device and a method of using it. The device is a foldable stent or stent-graft which may be percutaneously delivered with (or on) a catheter, typically an endovascular catheter, to a body cavity or lumen and then expanded. The stent's configuration allows it to be folded or otherwise compressed to a very small diameter prior to deployment without changing the length of the stent. The deployment procedures may involve the use of an outer sleeve to maintain the stent or stent-graft at a reduced diameter or may involve one or more external or internal “slip-lines” or “tether wires” to hold and then to release the device. A removal slip line for holding the stent in the deployable configuration can be woven along longitudinal fold line using the sack knot.
摘要翻译：本发明是医疗装置及其使用方法。该装置是可折叠的支架或支架移植物，其可以通过导尿管（通常为血管内导管）经皮递送至体腔或内腔，然后扩张。支架的构造允许其在展开之前被折叠或以其他方式压缩至非常小的直径，而不改变支架的长度。展开过程可涉及使用外套筒将支架或支架移植物保持在减小的直径或者可以涉及一个或多个外部或内部的“滑线”或“系绳”来保持并释放设备。用于将支架保持在可展开构造中的移除滑动线可以使用麻袋结构沿纵向折叠线编织。

33. 发明授权

US06582459B1 Stent delivery system 失效
标题翻译：支架输送系统
公开(公告)号：US06582459B1
公开(公告)日：2003-06-24
申请号：US09716571
申请日：2000-11-17
申请人： Lilip Lau , William M. Hartigan
发明人： Lilip Lau , William M. Hartigan
IPC分类号： A61F206
CPC分类号： A61F2/97 , A61F2/958 , A61F2002/9517 , A61M2025/0183 , A61M2025/1081
摘要： The invention is directed to a stent delivery method and system which generally includes an elongated delivery sheath and a catheter disposed within an outer lumen of the sheath having an expandable member on its distal extremity. An expandable stent is mounted on the expandable member of the catheter. The distal portion of the sheath tapers down and is tucked within an elastic cone during transport of the stent to a stenotic region. A manipulating device is provided on the proximal end of the delivery system to effect relative axial movement between the sheath and the catheter so as to expose the stent mounted on the expandable member on the catheter within a body lumen such as a coronary artery and allow the expansion of the stent by the expansion of the expandable member. The elastic cone thereby disengages from the sheath and collapses about the distal end of the catheter. The delivery sheath has a first port in its distal end and a second port in the sheath wall proximally disposed from the distal end of the sheath. The catheter likewise has a first port in its distal end and a second port proximally disposed from the distal end of the catheter. An inner lumen extends within the distal portion of the catheter between the first and second ports and slidably receives a guiding member such as a guidewire. This system allows the stent to be delivered over a guidewire previously advanced to the desired location within a body lumen.
摘要翻译：本发明涉及一种支架输送方法和系统，其通常包括细长的输送护套和设置在护套的外腔内的导管，其在其远端上具有可扩张构件。可扩张支架安装在导管的可扩张构件上。护套的远端部分在将支架运送到狭窄区域期间逐渐变细并且被折叠在弹性锥体内。操纵装置设置在输送系统的近端上以实现护套和导管之间的相对轴向移动，以便将安装在可扩张构件上的支架暴露在诸如冠状动脉的体腔内的导管上，并允许通过可扩张构件的膨胀来扩张支架。因此弹性锥体与护套分离并围绕导管的远端塌陷。输送护套在其远端具有第一端口，并且护套壁中的第二端口从护套的远端向近侧设置。导管同样具有其远端中的第一端口和从导管的远端向近侧设置的第二端口。内腔在第一和第二端口之间的导管的远端部分内延伸，并且可滑动地容纳诸如导丝的引导构件。该系统允许支架在先前推进到体腔内的期望位置的导丝上传送。

34. 发明授权

US6015429A Procedures for introducing stents and stent-grafts 失效
标题翻译：引入支架和支架移植物的程序
公开(公告)号：US6015429A
公开(公告)日：2000-01-18
申请号：US615016
申请日：1996-03-12
申请人： Lilip Lau , Charles T. Maroney , William M. Hartigan , Sharon Lam
发明人： Lilip Lau , Charles T. Maroney , William M. Hartigan , Sharon Lam
IPC分类号： A61F2/00 , A61F2/06 , A61F2/82 , A61F2/88 , A61F2/92
CPC分类号： A61F2/88 , A61F2/07 , A61F2/844 , A61F2/91 , A61F2/915 , A61F2/92 , A61F2/89 , A61F2/95 , A61F2002/061 , A61F2002/072 , A61F2002/075 , A61F2002/3008 , A61F2002/30093 , A61F2002/30462 , A61F2002/828 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2002/9511 , A61F2002/9665 , A61F2210/0019 , A61F2220/0075 , A61F2230/0039 , A61F2230/0041 , A61F2230/006 , A61F2230/0078 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00137 , A61F2310/00149
摘要： This invention is a medical device and a method of using it. The device is a foldable stent or stent-graft which may be percutaneously delivered with (or on) a catheter, typically an endovascular catheter, to a body cavity or lumen and then expanded. It may also be delivered or via surgical (or other) techniques. The expandable stent structure utilizes torsional members which distribute bending and folding loads in such a way that the stent is not plastically deformed. The stent's configuration allows it to be folded or otherwise compressed to a very small diameter prior to deployment without changing the length of the stent. The graft component cooperating with the stent is tubular and preferably is blood-compatible material which may, if desired, be reinforced with fibers. The stent is able to provide collapsible support for otherwise frangible graft material.The invention also involves procedures for folding stents and for deploying stents or stent-grafts which have been folded, bound, or otherwise collapsed to significantly smaller diameters for insertion into a human or animal body. When used with super-elastic alloys, the stent may be collapsed at a convenient temperature either above or, preferably, below the transition temperature of the alloy.
摘要翻译：本发明是医疗装置及其使用方法。该装置是可折叠的支架或支架移植物，其可以通过导尿管（通常为血管内导管）经皮递送至体腔或内腔，然后扩张。它也可以通过手术（或其他）技术递送。可扩展支架结构使用扭转构件，其以这样的方式分布弯曲和折叠负载，使得支架不会塑性变形。支架的构造允许其在展开之前被折叠或以其他方式压缩至非常小的直径，而不改变支架的长度。与支架配合的移植物组件是管状的，并且优选是血液相容的材料，如果需要，其可以用纤维增强。该支架能够为另外易碎的移植材料提供可折叠的支撑。本发明还涉及折叠支架和用于展开支架或支架移植物的过程，所述支架或支架移植物已被折叠，结合或以其他方式塌缩，以显着更小的直径插入到人或动物体内。当与超弹性合金一起使用时，支架可以在合金的转变温度以上或优选低于合金的转变温度的方便的温度下折叠。

35. 发明授权

US5603721A Expandable stents and method for making same 失效
标题翻译：可扩展支架及其制作方法
公开(公告)号：US5603721A
公开(公告)日：1997-02-18
申请号：US556516
申请日：1995-11-13
申请人： Lilip Lau , William M. Hartigan , John J. Frantzen
发明人： Lilip Lau , William M. Hartigan , John J. Frantzen
IPC分类号： A61F2/00 , A61F2/86 , A61F2/88 , C23F1/02 , C23F1/04 , A61M29/00
CPC分类号： A61F2/86 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , C23F1/02 , C23F1/04 , A61F2/848 , A61F2/958 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2210/0019 , A61M2025/1081 , Y10S623/901 , Y10S623/903 , Y10S623/921 , Y10T29/49995
摘要： The invention is directed to an expandable stent for implantation in a body lumen, such as an artery, and a method for making it from a single length of tubing. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common axis and interconnected by one or more interconnective elements. The individual radially expandable cylindrical elements consist of ribbon-like material disposed in an undulating pattern. Portions of the expanded stent project outwardly into engagement with the vessel wall to more securely attach the stent.
摘要翻译：本发明涉及用于植入体腔（例如动脉）中的可扩张支架，以及用于从单一管道制造它的方法。支架由多个径向可扩张的圆柱形元件组成，其大致在公共轴线上对准并且由一个或多个互连元件相互连接。各个可径向扩张的圆柱形元件由以波浪形图案布置的带状材料组成。扩张的支架的一部分向外突出地与血管壁接合，以更牢固地附接支架。

36. 发明授权

US5421955A Expandable stents and method for making same 失效
标题翻译：可扩展支架及其制作方法
公开(公告)号：US5421955A
公开(公告)日：1995-06-06
申请号：US214402
申请日：1994-03-17
申请人： Lilip Lau , William M. Hartigan , John J. Frantzen
发明人： Lilip Lau , William M. Hartigan , John J. Frantzen
IPC分类号： A61F2/00 , A61F2/86 , A61F2/88 , C23F1/02 , C23F1/04 , B44C1/22
CPC分类号： A61F2/86 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , C23F1/02 , C23F1/04 , A61F2/848 , A61F2/958 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2210/0019 , A61M2025/1081 , Y10S623/901 , Y10S623/903 , Y10S623/921 , Y10T29/49995
摘要： The invention is directed to an expandable stent for implantation in a body lumen, such as an artery, and a method for making it from a single length of tubing. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common axis and interconnected by one or more interconnective elements. The individual radially expandable cylindrical elements consist of ribbon-like material disposed in an undulating pattern. The stents are made by coating a length of tubing with an etchant-resistive material and then selectively removing portions of the coating to form a pattern for the stent on the tubing and to expose the portions of the tubing to be removed. This may done by machine-controlled activation and relative positioning of a laser in conjunction with the coated tubing. After the patterning of the tubing, the stent is formed by removing exposed portions of the tubing by an etching process.
摘要翻译：本发明涉及用于植入体腔（例如动脉）中的可扩张支架，以及用于从单一管道制造它的方法。支架由多个径向可扩张的圆柱形元件组成，其大致在公共轴线上对准并且由一个或多个互连元件相互连接。各个可径向扩张的圆柱形元件由以波浪形图案布置的带状材料组成。通过用耐腐蚀材料涂覆一段长度的管，然后选择性地去除涂层的部分以在管上形成用于支架的图案并露出待移除的管道的部分来制造支架。这可以通过机器控制的激活和激光与涂覆管道的相对定位来完成。在管道图案化之后，通过蚀刻工艺去除管道的暴露部分来形成支架。

37. 发明授权

US5242399A Method and system for stent delivery 失效
标题翻译：支架输送方法和系统
公开(公告)号：US5242399A
公开(公告)日：1993-09-07
申请号：US900122
申请日：1992-06-18
申请人： Lilip Lau , William M. Hartigan
发明人： Lilip Lau , William M. Hartigan
IPC分类号： A61F2/92 , B09B1/00 , E02D31/00 , G01M3/20
CPC分类号： A61F2/92 , A61F2/958 , B09B1/00 , E02D31/00 , G01M3/20 , A61F2002/9583 , A61F2230/0054 , A61M2025/1068 , A61M2025/1081 , A61M25/1006
摘要： A stent delivery system having an expandable stent in a contracted condition positioned on an expandable member, such as an inflatable balloon, disposed on the distal portion of an elongated catheter body. A guidewire extends through an inner lumen within the elongated catheter body and out its distal end. A tubular protective sheath is secured by its distal end to the portion of the guidewire which extends out of the distal end of the catheter body and fits over the rolled up stent mounted on the expandable member on the distal end of the catheter body. The catheter assembly is advanced to a desired location within a patient's body lumen, such as the patient's arterial system, with the sheath in place over the stent. Once in proper position, the guidewire is advanced distally in order to remove the attached sheath and completely expose the stent. The expandable member on the catheter is expanded to expand the stent. The stent is preferably self-locking in the expanded condition so that the expanded expandable member can be contracted and the catheter can be removed therefrom.
摘要翻译：一种支架输送系统，其具有设置在细长导管体的远端部分上的可膨胀构件（例如可充气气囊）处于收缩状态的扩张支架。导丝延伸穿过细长导管主体内的内腔并从其远端延伸出来。管状保护套由其远端固定到导丝线的远离导管主体的远端的部分，并且装配在安装在导管主体远端上的可扩张构件上的卷起的支架上。导管组件前进到患者体腔内的所需位置，例如患者的动脉系统，护套位于支架上方。一旦处于正确的位置，导丝线向远侧推进，以便去除附着的护套并完全暴露支架。导管上的可扩张构件被扩张以扩张支架。支架优选在膨胀状态下自锁，使得扩张的可扩张构件可以收缩并且可以从中移除导管。

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