专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明专利

NO20016246L 未知
公开(公告)号：NO20016246L
公开(公告)日：2002-03-04
申请号：NO20016246
申请日：2001-12-19
申请人： LILLY CO ELI
发明人： BLEAKMAN DAVID , CHAPPELL AMY SUZON , FILLA SANDRA ANN , JOHNSON KIRK WILLIS , ORNSTEIN PAUL LESLIE
IPC分类号： A61K31/00 , A61K45/00 , A61K31/472 , A61K31/4725 , A61K31/5377 , A61P21/02 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/02 , A61P43/00 , C07D401/06 , A61K
摘要： The present invention provides a method of treating or preventing migraine comprising administering to a patient in need thereof an effective amount of a selective iGluR 5 receptor antagonist. The present invention further provides novel compounds functional as selective iGluR 5 receptor antagonists as well as compositions and formulations comprising said selective iGluR 5 receptor antagonists.

32. 发明专利

NO20016246A 未知
公开(公告)号：NO20016246A
公开(公告)日：2002-03-04
申请号：NO20016246
申请日：2001-12-19
申请人： LILLY CO ELI
发明人： BLEAKMAN DAVID , CHAPPELL AMY SUZON , FILLA SANDRA ANN , JOHNSON KIRK WILLIS , ORNSTEIN PAUL LESLIE
IPC分类号： A61K45/00 , A61K31/00 , A61K31/472 , A61K31/4725 , A61K31/5377 , A61P21/02 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/02 , A61P43/00 , C07D401/06 , A61K
CPC分类号： C07D401/06 , A61K31/00 , A61K31/472 , A61K31/4725

33. 发明专利

ECSP014079A DERIVADOS DE SULFONAMIDA 未知
公开(公告)号：ECSP014079A
公开(公告)日：2002-02-25
申请号：ECSP014079
申请日：2001-05-18
申请人： LILLY CO ELI
发明人： ORNSTEIN PAUL LESLIE , ZARRINMAYEH HAMIDEH , ZIMMERMAN DENNIS MICHAEL , FRAY ANDREW HENDLEY , MILLER WILLIAM DAVID , AIKINS JAMES ABRAHAM
IPC分类号： A61P25/18 , A61K31/18 , A61P25/24 , A61P25/28 , A61P43/00 , C07B53/00 , C07C303/38 , C07C303/40 , C07C311/03 , C07C311/05
摘要： La presente invención se refiere a un compuesto de fórmula I (gráfico), o una sal farmacéuticamente aceptable del mismo, que es útil para el tratamiento de afecciones asociadas con la hipofusión como trastornos psiquiátricos y neurológicos.

34. 发明专利

NO20016246D0 未知
公开(公告)号：NO20016246D0
公开(公告)日：2001-12-19
申请号：NO20016246
申请日：2001-12-19
申请人： LILLY CO ELI
发明人： BLEAKMAN DAVID , CHAPPELL AMY SUZON , FILLA SANDRA ANN , JOHNSON KIRK WILLIS , ORNSTEIN PAUL LESLIE
IPC分类号： A61K31/00 , A61K45/00 , A61K31/472 , A61K31/4725 , A61K31/5377 , A61P21/02 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/02 , A61P43/00 , C07D401/06 , A61K
摘要： The present invention provides a method of treating or preventing migraine comprising administering to a patient in need thereof an effective amount of a selective iGluR 5 receptor antagonist. The present invention further provides novel compounds functional as selective iGluR 5 receptor antagonists as well as compositions and formulations comprising said selective iGluR 5 receptor antagonists.

35. 发明专利

CA2409829A1 SULFONAMIDE DERIVATIVES 未知
公开(公告)号：CA2409829A1
公开(公告)日：2001-11-29
申请号：CA2409829
申请日：2001-05-04
申请人： LILLY CO ELI
发明人： FRAY ANDREW HENDLEY , AIKINS JAMES ABRAHAM , ZIMMERMAN DENNIS MICHAEL , ZARRINMAYEH HAMIDEH , MILLER WILLIAM DAVID , ORNSTEIN PAUL LESLIE
IPC分类号： A61P25/18 , A61K31/18 , A61P25/24 , A61P25/28 , A61P43/00 , C07B53/00 , C07C303/38 , C07C303/40 , C07C311/03 , C07C311/05
摘要： The present invention relates to a compound of formula (Ia) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders.

36. 发明专利

CO5080788A1 DERIVADOS DE SULFONAMIDA 未知
公开(公告)号：CO5080788A1
公开(公告)日：2001-09-25
申请号：CO99047633
申请日：1999-07-28
申请人： LILLY CO ELI
发明人： MACKLIN BRIAN ARNOLD , BENDER DAVID MICHAEL , WINTON DENNIS JONES , ORNSTEIN PAUL LESLIE , SIMON RICHARD LEE , ZIMMERMAN DENNIS MICHAEL
IPC分类号： A61K31/18 , A61K31/381 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61P25/18 , A61P25/24 , A61P25/28 , A61P43/00 , C07C311/03 , C07C311/04 , C07C311/13 , C07D213/26 , C07D213/42 , C07D213/81 , C07D213/82 , C07D333/16 , C07D333/20
摘要： Un compuesto de fórmula : En la que :uno o ambos de Ra y Rb se seleccionan independientemente de F, CF3 y ORc , siendo Rc hidrógeno o alquilo C1-C4 y cualquiera del resto hidrógeno; o Ra y Rb juntos representan =O o =CH2;R1 representa un grupo naftilo o un grupo fenilo, tienilo o piridilo que no está sustituido o está sustituido por uno o dos sustituyentes seleccionados independientemente de halógeno; nitro; ciano; hidroxiimino; alquilo C1-C10; alquenilo C2-C10; alquinilo C2-C10; cicloalquilo C3-C8; hidroxi (cicloalquilo C3-C8); oxo(cicloalquilo C3-C8); halo (alquilo C1-C10); (CH2 )y X1 R9, donde y es 0 o un entero de 1 a 4, X1 representa O, S, NR10, CO, COO, OCO; CONR11, NR12CO, NR12COCOO u OCONR13, R9 representa hidrógeno, alquilo C1-C10, alquenilo C3-C10, alquinilo C3-C10, pirrolidinilo, tetrahidrofurilo, morfolino o cicloalquilo C3-C8 y cada uno de R10, R11, R12 y R13 representa independientemente hidrógeno o alquilo C1-C10, o R9, R10, R11, R12 o R13 junto con el átomo de nitrógeno al que están unidos forman un grupo azetidinilo, pirrolidinilo, piperidinilo o morfolino; N-(alquil C1-C4)piperazinilo; N-fenil(alquil C1-C4)piperazinilo; tienilo; furilo; oxazolilo; isoxazolilo; pirazolilo; imidazolilo; tiazolilo; piridilo; piridazinilo; pirimidinilo; dihidrotienilo; dihidrofurilo; dihidrotiopiranilo; dihidropiranilo; dihidrotiazolilo; (alcoxi C1-C4)-carbonildihidrotiazolilo; (alcoxi C1-C4)-carbonildimetildihidrotiazolilo; tetrahidrotienilo; tetrahidrofurilo; tetrahidrotiopiranilo; tetrahidropiranilo; indolilo; benzofurilo; benzotienilo; bencimidazolilo; y un grupo de fórmula R14-(La )n-X2 -(Lb)m en el que X2 representa un enlace, O, NH, S, SO, SO2; CO, CH(OH), CONH, NHCO, NHCONH, NHCOO, COCONH, OCH2CONH o CH=CH, La y Lb representan cada uno alquileno C1-C4, uno de n y m es 0 ó 1 y el otros es 0, y R14 representa un grupo fenilo o heteroaromático que no está sustituido o está sustituido por uno o dos de halógeno, nitro, ciano, hidroxiimino, alquilo C1-C10, alquenilo C2-C10, alquinilo C2-C10, cicloalquilo C3-C8, 4-(1,1-dioxotetrahidro-1,2-tiazinilo), halo(alquilo C1-C10), ciano(alquenilo C2-C10), fenilo y (CH2)zX3R15, donde z es O o un entero de 1 a 4, X3 representa O, S, NR16, CO, CH(OH), COO, OCO, CONR17, NR18CO, NHS02, NHS02NR17, NHCONH, OCONR19 o NR19COO, R15 representa hidrógeno, ...

37. 发明专利

CA2378613A1 SELECTIVE IGLUR5 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF MIGRAINE 未知
公开(公告)号：CA2378613A1
公开(公告)日：2001-01-11
申请号：CA2378613
申请日：2000-06-27
申请人： LILLY CO ELI
发明人： ORNSTEIN PAUL LESLIE , JOHNSON KIRK WILLIS , BLEAKMAN DAVID , FILLA SANDRA ANN , CHAPPELL AMY SUZON
IPC分类号： A61K45/00 , A61K31/00 , A61K31/472 , A61K31/4725 , A61K31/5377 , A61P21/02 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/02 , A61P43/00 , C07D401/06 , C07D413/06
摘要： The present invention provides a method of treating or preventing migraine comprising administering to a patient in need thereof an effective amount of a selective iGluR5 receptor antagonist. The present invention further provides novel compounds functional as selective iGluR5 receptor antagonists as well as compositions and formulations comprising said selective iGluR5 receptor antagonists.

40. 发明专利

TR9902449T2 未知
公开(公告)号：TR9902449T2
公开(公告)日：2000-07-21
申请号：TR9902449
申请日：1998-04-06
申请人： LILLY CO ELI
发明人： BLEAKMAN DAVID , HELTON DAVID R , IYENGAR SMRITI , LODGE DAVID , ORNSTEIN PAUL LESLIE
IPC分类号： A61P25/04 , A61K31/00 , A61K31/47 , A61K31/472 , A61K31/4725 , A61K45/00 , A61P43/00 , C07D217/26 , C07D401/12 , C07D217/06
CPC分类号： A61K31/472 , A61K31/00 , A61K31/47 , A61K31/4725 , C07D217/26 , C07D401/12

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式