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31. 发明授权

US5783269A Non-PVC multilayer film for medical bags 失效
标题翻译：医用袋非PVC多层膜
公开(公告)号：US5783269A
公开(公告)日：1998-07-21
申请号：US638249
申请日：1996-04-26
申请人： Klaus Heilmann , Thomas Nicola , Thomas Kreischer
发明人： Klaus Heilmann , Thomas Nicola , Thomas Kreischer
IPC分类号： B65D30/02 , A61J1/10 , B29C47/06 , B32B7/02 , B32B27/00 , B32B27/32 , B65D65/40 , B32B1/08
CPC分类号： B32B27/32 , Y10T428/1334 , Y10T428/1352 , Y10T428/1359 , Y10T428/2826 , Y10T428/31909 , Y10T428/31913 , Y10T428/31917 , Y10T428/31924 , Y10T428/31931
摘要： Non-PVC multi-layer film (1) containing an outer layer (2), a supporting layer (4) together with at least one interposed central layer (3), characterized in that the outer (2) and supporting (4) layers contain polymers having Vicat softening temperatures of above approximately 121.degree. C. and that at least one central layer (3) contains polymers having softening temperatures of below approximately 70.degree. C. The non-PVC multi-layer film (1) is particularly suitable for the production of medical bags, in particular multi-chamber bags, as the materials of the individual layers (2-4) are selected in such a manner that the film is transparent and flexible, but in particular also heat-sterilizable, fusible and heat sealable. The film is moreover completely recyclable.
摘要翻译：包含外层（2），支撑层（4）以及至少一个插入的中间层（3）的非PVC多层膜（1），其特征在于，外层（2）和支撑层（4）层含有维卡软化温度高于约121℃的聚合物，并且至少一个中心层（3）含有软化温度低于约70℃的聚合物。非PVC多层膜（1）特别适用于作为单层（2-4）的材料，以这样的方式选择医用袋，特别是多室袋的生产，使得膜是透明和柔性的，但是特别地也是热可灭菌，易熔和热可密封此外，电影完全可回收。

32. 发明授权

US5268144A Method for sterilizing a medical unit 失效
标题翻译：对医疗单元进行消毒的方法
公开(公告)号：US5268144A
公开(公告)日：1993-12-07
申请号：US921907
申请日：1992-07-29
申请人： Klaus Heilmann , Bernd Mathieu , Michael Rink , Wolfram Weber
发明人： Klaus Heilmann , Bernd Mathieu , Michael Rink , Wolfram Weber
IPC分类号： A61L2/04 , A61L2/18 , A61M1/16 , B01D65/02 , A61L2/06 , A61L2/16
CPC分类号： A61L2/18 , A61L2/04 , B01D65/022 , A61M1/169 , B01D2321/08 , B01D2321/162
摘要： This invention relates to a method for sterilizing a medical unit having at least two connections for a fluid flow pathway where a sterilizing medium flows through the medical unit.Medical units of this type are e.g. medical filters, in particular dialyzers. A high degree of sterility is here required. This is accomplished through the steps of:(a) inserting the medical unit into a system under pressure-tight coupling of the at least two connections to a feed conduit and discharge conduit of the system under atmospheric conditions;(b) passing the sterilizing medium from the system through the medical unit for a given period of time;(c) closing the at least two connections in the coupled state and in a germproof manner, without the same being opened, on completion of the sterilization operation; and(d) removing said medical unit from said system as a sterile medical unit with closed connections.All steps, including the removal of the medical unit, are therefore carried out in a system where the sterility obtained is constantly maintained. This "inline sterilization" guarantees a high degree of sterility of the medical units treated.
摘要翻译：本发明涉及一种消毒医疗单元的方法，该医疗单元具有至少两个用于流体通路的连接，其中消毒介质流过医疗单元。这种类型的医疗单位是例如。医疗过滤器，特别是透析器。这里需要高度的无菌性。这通过以下步骤来实现：（a）在大气条件下，将至少两个连接压力联接到系统的进料管道和排出管道，将医疗单元插入系统中; （b）将灭菌介质从系统通过医疗单位一段给定的时间; （c）在所述灭菌操作完成时，在所述连接状态下并以无菌方式封闭所述至少两个连接件而不相同地打开; 和（d）将所述医疗单元从所述系统中移除为具有封闭连接的无菌医疗单元。因此，所有步骤，包括移除医疗单元，都是在不断得到不育的系统中进行的。这种“在线灭菌”保证所治疗的医疗单位的高度的无菌性。

33. 发明授权

US4906375A Asymmetrical microporous hollow fiber for hemodialysis 失效
标题翻译：用于血液透析的不对称微孔中空纤维
公开(公告)号：US4906375A
公开(公告)日：1990-03-06
申请号：US188719
申请日：1988-04-29
申请人： Klaus Heilmann
发明人： Klaus Heilmann
IPC分类号： B22D2/00 , B22D11/18 , D01D5/247 , B01D39/16
CPC分类号： B22D2/006 , B22D11/182 , Y10T428/2975
摘要： An asymmetric microporous hollow fiber for hemodialysis is made up of 90 to 99% by weight of a first hydrophobic polymer and 10 to 1% by weight of a second hydrophilic polymer. The fiber has a water adsorbing capacity of 3 to 10% and is produced by extruding a solution containing 12 to 20% by weight of the first polymer and 2 to 10% by weight of the second polymer, the rest being a solvent to give a continuous hollow structure with a wall, causing a precipitation liquor to act on said structure in an outward direction through the wall thereof with the full precipitation thereof and the concurrent dissolution and washing out of a part of said first polymer from said extruded structure and then washing out the dissolved out part of the pore-forming substance and the other organic components. Thereafter the fiber so produced is fixed in a washing bath.
摘要翻译：用于血液透析的不对称微孔中空纤维由90至99重量％的第一疏水性聚合物和10至1重量％的第二亲水性聚合物组成。纤维的吸水能力为3〜10％，通过挤出含有12〜20重量％的第1聚合物和2〜10重量％的第2聚合物的溶液来制造，其余为溶剂，具有壁的连续中空结构，使沉淀液沿其向外的方向通过其全部沉淀作用在所述结构上，并且从所述挤出结构同时溶解和洗出部分所述第一聚合物，然后洗涤将部分成孔物质和其他有机成分溶解掉。此后将如此制造的纤维固定在洗涤浴中。

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