专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

US4592495A Automatic gun for discharging thermoplastic resin 失效
标题翻译：自动喷枪用于排出热塑性树脂
公开(公告)号：US4592495A
公开(公告)日：1986-06-03
申请号：US450260
申请日：1982-12-16
申请人： Masaaki Toda , Yoshio Ichikawa
发明人： Masaaki Toda , Yoshio Ichikawa
IPC分类号： B05C5/00 , B05B13/04 , B05C11/10 , B67D3/00
CPC分类号： B05C11/1042 , B05B13/0431
摘要： An automatic hot melt adhesive dispensing gun is connected by a swivel assembly to a working arm of a programmable working machine. The swivel assembly includes a hollow spindle journalled in the gun block of the gun. The free end of the spindle is connected to a hot melt adhesive source via a hose. The gun block rotates relative to the spindle. The gun can thus move in response to the movement of the working arm without exerting harmful torques on the hose.
摘要翻译：自动热熔胶分配枪通过旋转组件连接到可编程工作机的工作臂。旋转组件包括轴颈安装在枪的枪块中的中空心轴。主轴的自由端通过软管连接到热熔胶源。枪块相对于主轴旋转。因此，枪可以响应于工作臂的运动而移动，而不会在软管上施加有害的扭矩。

32. 发明授权

US5508450A Benzopyran derivatives 失效
标题翻译：苯并吡喃衍生物
公开(公告)号：US5508450A
公开(公告)日：1996-04-16
申请号：US316332
申请日：1994-09-30
申请人： Shuichi Ohuchida , Masaaki Toda , Tsumoru Miyamoto
发明人： Shuichi Ohuchida , Masaaki Toda , Tsumoru Miyamoto
IPC分类号： C07D311/72 , C07D311/92 , C07D311/04
CPC分类号： C07D311/92 , C07D311/72
摘要： Benzopyran derivatives which have an inhibitory effect on the Maillard reaction as well as an antioxidizing effect are described herein. These derivatives may be utilized in the treatment and/or prevention of diabetic complications such as, for example, coronary heart disease, peripheral circulatory insufficiency or failure, cerebrovascular hindrance, neurogenous diabetes, nephropathy, arteriosclerosis, arthrosclerosis, cataracts and retinopathy. Further, the derivatives may also be used in the treatment and/or prevention of diseases induced by aging and in the treatment and/or prevention of diseases caused by the formation of peroxidized fat.
摘要翻译：本文描述了对美拉德反应具有抑制作用以及抗氧化作用的苯并吡喃衍生物。这些衍生物可用于治疗和/或预防糖尿病并发症，例如冠心病，周围循环功能不全或失败，脑血管障碍，神经源性糖尿病，肾病，动脉硬化，关节动脉硬化，白内障和视网膜病变。此外，衍生物还可以用于治疗和/或预防由老化引起的疾病和治疗和/或预防由形成过氧化脂肪引起的疾病。

33. 发明授权

US5262431A Prolinal derivatives and pharmaceutical compositions thereof 失效
标题翻译：脯氨酸衍生物及其药物组合物
公开(公告)号：US5262431A
公开(公告)日：1993-11-16
申请号：US836971
申请日：1992-02-19
申请人： Masaaki Toda , Shuichi Ohuchida , Hiroyuki Ohno
发明人： Masaaki Toda , Shuichi Ohuchida , Hiroyuki Ohno
IPC分类号： C07D207/08 , A61K31/40 , C07D213/24
CPC分类号： C07D207/08
摘要： A novel prolinal derivative of general formula: ##STR1## [wherein A represents a group of the general formula: ##STR2## (wherein one of R.sup.1 and R.sup.2 represents hydrogen atom and the other represents alkyl group of from 2 to 5 carbon atoms, alkoxy group of from 1 to 5 carbon atom(s), phenyl group, benzyl group, cycloalkyl group of from 4 to 6 carbon atoms or (cycloalkyl group of from 4 to 6 carbon atoms)--methyl group or R.sup.1 and R.sup.2 each represents, same or different, alkyl group of from 1 to 4 carbon atom(s).) or a group of the general formula: ##STR3## (wherein m represents an integer of from 3 to 6.) n represents an integer of from 3 to 10.D represents carbocyclic or heterocyclic ring unsubstituted or substituted by from one to three of halogen atom, nitro group, trifluoromethyl group, alkyl or alkoxy group of from 1 to 4 carbon atom(s).]possess inhibitory activity on prolyl endopeptidase, and therefore be useful for treating and/or preventing agent for amnesia.
摘要翻译：一种新型的通式为：其中A表示通式为：IMA的基团（其中R 1和R 2中的一个表示氢原子，另一个表示2至5个碳原子的烷基）原子，1〜5个碳原子的烷氧基，苯基，苄基，4〜6个碳原子的环烷基或（4〜6个碳原子的环烷基） - 甲基或者R 1和R 2各自表示相同或不同的1至4个碳原子的烷基）或下列通式的基团：其中m表示3至6的整数。n表示从 D表示未被取代或被1至3个卤素原子，硝基，三氟甲基，1至4个碳原子的烷基或烷氧基取代的碳环或杂环]具有对脯氨酰内肽酶的抑制活性，因此可用于治疗和/或预防健忘症药物。

34. 发明授权

US5091406A Prolinal derivatives 失效
标题翻译：乳制品
公开(公告)号：US5091406A
公开(公告)日：1992-02-25
申请号：US479493
申请日：1990-02-07
申请人： Masaaki Toda , Shuichi Ohuchida , Hiroyuki Ohno
发明人： Masaaki Toda , Shuichi Ohuchida , Hiroyuki Ohno
IPC分类号： C07D207/08
CPC分类号： C07D207/08
摘要： A prolinal derivative of general formula: ##STR1## [wherein A represents alkylene group of from 1 to 4 carbon atom(s) or saturated hydrocarbon ring of from 3 to 7 carbon atoms,n represents a number 2, 3 or 4,D represents carbocyclic or heterocyclic ring unsubstituted orsubstituted by from one to three of halogen atom, alkyl or alkoxy group of from 1 to 4 carbon atom(s), nitro group or trifluoromethyl group.]. possess inhibitory activity on prolyl endopeptidase, and therefore be useful for treating and/or preventing agent for amnesia.

35. 发明授权

US4977180A Novel prolinal derivatives 失效
标题翻译：新颖的流涎衍生物
公开(公告)号：US4977180A
公开(公告)日：1990-12-11
申请号：US151862
申请日：1988-02-03
申请人： Masaaki Toda , Shuichi Ohuchida , Hiroyuki Ohno
发明人： Masaaki Toda , Shuichi Ohuchida , Hiroyuki Ohno
IPC分类号： C07D207/08
CPC分类号： C07D207/08
摘要： A novel prolinal derivative of general formula: ##STR1## wherein A represents alkylene group of from 1 to 4 carbon atom(s) or saturated hydrocarbon ring of from 3 to 7 carbon atoms, n represents a number 2, 3 or 4, D represents carbocyclic or heterocyclic ring unsubstituted or substituted by from one to three of halogen atom, alkyl or alkoxy group of from 1 to 4 carbon atom(s), nitro group or trifluromethyl group posses inhibitory activity on prolyl endopeptidase, and therefore are useful for treating and/or preventing agent for amnesia.

36. 发明授权

US4956380A Prolinal compounds useful in treating amnesia 失效
标题翻译：可用于治疗遗忘症的肛门化合物
公开(公告)号：US4956380A
公开(公告)日：1990-09-11
申请号：US123410
申请日：1987-11-20
申请人： Masaaki Toda , Shuichi Ohuchida , Hiroyuki Ohno
发明人： Masaaki Toda , Shuichi Ohuchida , Hiroyuki Ohno
IPC分类号： A61K31/40 , A61K31/401 , A61K31/4025 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61P25/28 , C07D207/08 , C07D401/12 , C07D405/12 , C07D409/12
CPC分类号： C07D207/08 , C07D405/12
摘要： Novel prolinal derivatives of the general formula: ##STR1## wherein A represents alkylene group of from 1 to 8 carbon atoms or alkenylene group of from 2 to 8 carbon atom(s) or a saturated hydrocarbon ring of from 3 to 7 carbon atoms, R represents hydrogen atom, phenyl group, benzyl group, alkyl group of from 1 to 8 carbon atom(s) or cycloalkyl group of from 3 to 7 carbon atoms,B represents alkylene group of from 1 to 8 atom(s) unsubstituted or substituted by phenyl group or benzyl group, or a single bond,D represents carbocyclic or heterocyclic ring unsubstituted or substituted by from one to three of halogen atom, alkyl or alkoxy group of from 1 to 4 carbon atom(s), nitro group or trifluoromethyl group which prolinal derivatives possess inhibitory activity on prolyl endopeptidase, and therefore are useful as a treating or preventing agent for amnesia.

37. 发明授权

US4847275A (Fused) benz (thio) amides 失效
标题翻译：（熔融）苯（硫）酰胺
公开(公告)号：US4847275A
公开(公告)日：1989-07-11
申请号：US207994
申请日：1988-06-17
申请人： Masaaki Toda , Tumoru Miyamoto , Yoshinobu Arai
发明人： Masaaki Toda , Tumoru Miyamoto , Yoshinobu Arai
IPC分类号： A61K31/165 , A61K31/35 , A61K31/41 , C07C233/29 , C07C233/75 , C07C235/38 , C07C235/56 , C07C235/64 , C07C323/52 , C07D215/48 , C07D257/04 , C07D311/24 , C07D319/20 , C07D401/04 , C07D405/04 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04
CPC分类号： C07D257/04 , C07C233/29 , C07C233/75 , C07C235/38 , C07C235/56 , C07C235/64 , C07C323/52 , C07D215/48 , C07D311/24 , C07D319/20 , C07D401/04 , C07D405/04 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07C2101/14
摘要： A (fused) benz (thio) amide of the general formula: ##STR1## (wherein, symbol A represents a single bond or a group of methylene, ethylene, trimethylene, tetramethylene, vinylene, propenylene, butenylene, butadienylene or ethynylene group optionally being substituted by one, two or three of straight or branched alkyl group(s) of from 1 to 10 carbon atom(s) and/or phenyl group(s);B represents a group of the general formula: ##STR2## T represents an oxygen atom or a sulphur atom; R.sup.1 represents a group of general formula: ##STR3## (iv) a straight or branched alkyl, alkenyl or alkynyl group of from 1 to 20 carbon atom(s);(wherein R.sup.5 and R.sup.6 independently represent a hydrogen atom or a halogen atom or a straight or branched alkyl, alkenyl or alkynyl group of from 1 to 20 carbon atom(s) being unreplaced or replaced one, two, three, four or five of optional carbon atom(s) by oxygen atom(s), sulphur atom(s), halogen atom(s), nitrogen atom(s), benzene ring(s), thiophene ring(s), naphthalene ring(s), carbocyclic ring(s) of from 4 to 7 carbon atom(s), carbonyl group(s), carbonyloxy group(s), hydroxy group(s), carboxy group(s), azido group(s) and/or nitro group(s));R.sup.2 represents a hydrogen atom or a straight or branched alkyl group of from 1 to 6 carbon atom(s);R.sup.3 represents a hydrogen atom, a halogen atom, a hydroxy group, a nitro group, a group of general formula: --COOR.sup.7 (wherein R.sup.7 represents a hydrogen atom or a straight or branched alkyl group of from 1 to 6 carbon atom(s).) or a straight or branched alkyl, alkoxy or alkylthio group of from 1 to 6 carbon atom(s).R.sup.4 represents(i) when symbol B represents a closed ring, a group of general formula: ##STR4## (wherein symbol U represents an oxygen atom or a sulphur atom. R.sup.8 represents a hydrogen atom or a straight or branched alkyl group of from 1 to 6 carbon atom(s). n and m represent an integer of from 1 to 10, respectively, p and q represent zero or an integer of from 1 to 10, respectively;)or non-toxic salts thereof possess an antagonistic activity on leukotrienes (SRS), inhibitory activity on 5.alpha.-reductase, on phospholipase and on aldose reductase and are therefore useful for the prevention and/or treatment for diseases induced by leukotrienes, 5.alpha.-reductase, phospholipase and aldose reductase in mammals, especially human beings.

38. 发明授权

US4780469A (Fused) benz(thio)amides and pharmaceutical use 失效
标题翻译：（熔融）苯（硫）酰胺和药用
公开(公告)号：US4780469A
公开(公告)日：1988-10-25
申请号：US767538
申请日：1985-08-20
申请人： Masaaki Toda , Tumoru Miyamoto , Yoshinobu Arai
发明人： Masaaki Toda , Tumoru Miyamoto , Yoshinobu Arai
IPC分类号： A61K31/165 , A61K31/35 , A61K31/41 , C07C233/29 , C07C233/75 , C07C235/38 , C07C235/56 , C07C235/64 , C07C323/52 , C07D215/48 , C07D257/04 , C07D311/24 , C07D319/20 , C07D401/04 , C07D405/04 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D309/30 , C07D405/02
CPC分类号： C07D257/04 , C07C233/29 , C07C233/75 , C07C235/38 , C07C235/56 , C07C235/64 , C07C323/52 , C07D215/48 , C07D311/24 , C07D319/20 , C07D401/04 , C07D405/04 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07C2101/14
摘要： A (fused) benz(thio)amide of the formula: ##STR1## wherein B represents(i) a carbocyclic ring of from 4 to 8 members being unreplaced or replaced one, two or three of optional carbon atom(s) by oxygen, nitrogen and/or sulphur atom(s) or(ii) a divalent group of the formula: ##STR2## R.sup.1 represents a group of formula: ##STR3## (iv) a straight or branched alkyl, alkenyl, or alkynyl of from 1 to 20 carbon atoms,R.sup.4 represents(i) when B represents a closed ring, a group of the formula: ##STR4## (ii) when B does not represent a ring, a group of formula: ##STR5## with the proviso that compounds of formula: ##STR6## wherein A' is a vinylene or an ethylene group optionally substituted by straight or branched alkyl groups of from 1 to 4 carbon atom(s);R.sup.4' is--(CH.sub.2).sub.n --COOR.sup.8 andR.sup.1' is(i) a group of the formula: ##STR7## or (ii) a group of the formula: ##STR8## are excluded, wherein A, R.sup.2, R.sup.3, R.sup.5, R.sup.6, R.sup.7, R.sup.8, U, n, m, p, q, R.sup.5', and R.sup.6' are defined as in the above specification, possessing antagonistic activity on leukotrienes (SRS), inhibitory activity on 5.alpha.-reductase, on phospholipase and on aldose reductase and being useful for the prevention and/or treatment of diseases induced by leukotrienes, 5.alpha.-reductase, phospholipase and aldose reductase in mammals, especially in human beings.
摘要翻译：（I）的（稠合的）苯并（硫代）酰胺其中B表示（i）4至8个成员的碳环不被替换或替换一个，两个或三个任选的碳原子，通过氧，氮和/或硫原子或（ii）下式的二价基团：R 1表示下式的基团：（i）（ii）（iii ）（iv）1至20个碳原子的直链或支链烷基，烯基或炔基，R4表示（i）当B表示闭环时，下式为：U（CH2）nCOOR8（CH2））pCOOR8或（ii）当B不表示环时，具有式（CH 2）p COOR 8或的基团，条件是式：其中A'是亚乙烯基或亚乙烯基任选被1至4个碳原子的直链或支链烷基取代的基团; R4'是 - （CH2）n-COOR8-，R1'是（i）下式的基团：其中A，R2，R3， R5，R6，R7，R8，U，n，m，p，q，R5'和R6'如上述说明书所定义，对白细胞三烯（SRS）具有拮抗作用，对5α-还原酶具有抑制活性磷脂酶和醛糖还原酶，并且可用于预防和/或治疗哺乳动物，特别是人中由白三烯，5α-还原酶，磷脂酶和醛糖还原酶诱导的疾病。

39. 发明授权

US08420449B2 Laser patterning apparatus and laser patterning method 失效
标题翻译：激光图案装置和激光图案化方法
公开(公告)号：US08420449B2
公开(公告)日：2013-04-16
申请号：US13234825
申请日：2011-09-16
申请人： Masaaki Toda , Satoshi Sawayanagi
发明人： Masaaki Toda , Satoshi Sawayanagi
IPC分类号： H01L21/50 , H01L21/48 , H01L21/46
CPC分类号： H01L31/18 , B23K26/0006 , B23K26/359 , B23K26/40 , B23K2103/50 , B23K2103/56
摘要： Aspects of the invention are directed to laser patterning apparatus capable of performing laser patterning on a thin film formed on a flexible substrate with a good yield and a laser patterning method thereof. The thin film formed on the flexible substrate can be patterned by laser using a laser patterning apparatus that can include a processing stage that has a reference processing surface on which the flexible substrate having the thin film formed thereon is disposed, a wrinkle removing device that is configured as a mechanism for stretching an outer periphery of a processing region of the flexible substrate so that tension is applied outward in the width direction and forward and backward in the transporting direction, and a laser scanner that scans a predetermined line of the thin film formed on the flexible substrate while emitting a laser beam thereto.
摘要翻译：本发明的方面涉及能够以高产率在形成在柔性基板上的薄膜上进行激光图案化的激光图案形成装置及其激光图案化方法。形成在柔性基板上的薄膜可以通过使用激光图案形成装置的激光来图案化，该激光图案形成装置可以包括具有设置有形成有薄膜的柔性基板的参考处理表面的处理台，被配置为用于拉伸柔性基板的处理区域的外周的机构，使得沿宽度方向向外施加张力并在输送方向上向前和向后施加张力;以及激光扫描器，其扫描形成的薄膜的预定线在柔性基板上同时向其发射激光束。

40. 再颁专利

USRE36385E Glucopyranose derivatives 失效
标题翻译：吡喃葡萄糖衍生物
公开(公告)号：USRE36385E
公开(公告)日：1999-11-09
申请号：US64549
申请日：1993-05-20
申请人： Masaaki Toda , Yutaro Sasaki , Katsuichi Shimoji
发明人： Masaaki Toda , Yutaro Sasaki , Katsuichi Shimoji
IPC分类号： C07H13/04 , C07H13/06 , C07H15/04 , C07H15/18 , A61K31/00 , C07D309/00 , C07H11/00 , C07H13/00
CPC分类号： C07H13/04 , C07H13/06 , C07H15/04 , C07H15/18
摘要： This invention relates to glucopyranose compounds of formula (I) and (IA) ##STR1## and the non-toxic salts thereof wherein the substituents are as defined herein. Such materials possess enhancing activity of cellular immunity (e.g. mitogenic activity) to living tissue and therefore are useful as anti-tumor agents.
摘要翻译：本发明涉及式（I）和（IA）的吡喃葡萄糖化合物及其无毒盐，其中取代基如本文所定义。这样的物质具有提高活体组织的细胞免疫活性（例如有丝分裂活性），因此可用作抗肿瘤剂。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式