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31. 发明申请

WO2004071335A8 FILTER MEMBRANE MANUFACTURING METHOD 审中-公开
标题翻译：过滤膜制造方法
公开(公告)号：WO2004071335A8
公开(公告)日：2005-03-10
申请号：PCT/US2004002115
申请日：2004-01-26
申请人： BOSTON SCIENT LTD , CRANK JUSTIN , ANDERSON NARIN , HANSEN JAMES G , LIN HORNG-BAN , SMITH MARK , TRAN THE THOMAS TRINH , DAO KINH-LUAN D , CHIN YEM , ZHONG SHENG-PING , ANDERSON JAMES M , VOGEL JEFFERY H
发明人： CRANK JUSTIN , ANDERSON NARIN , HANSEN JAMES G , LIN HORNG-BAN , SMITH MARK , TRAN THE THOMAS TRINH , DAO KINH-LUAN D , CHIN YEM , ZHONG SHENG-PING , ANDERSON JAMES M , VOGEL JEFFERY H
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/0067 , A61F2230/008
摘要： An embolic protection filter and method of making the same. An embolic protection filter may include a filter membrane or material (16) having a plurality of holes. In some embodiments, the filter membrane may be manufactured by spray coating a filter material onto a forming member or spray mold (26, 126, 226, 426, 626, 826).
摘要翻译：栓塞保护过滤器及其制作方法。栓塞保护过滤器可以包括具有多个孔的过滤膜或材料（16）。在一些实施例中，过滤膜可以通过将过滤材料喷涂到成形构件或喷雾模具（26,126,226,426,626,826）上来制造。

32. 发明专利

CA3079281A1 REVERSE HORSE CART 未知
公开(公告)号：CA3079281A1
公开(公告)日：2020-10-23
申请号：CA3079281
申请日：2020-04-23
申请人： SMITH MARK
发明人： SMITH MARK
IPC分类号： B60K8/00 , A01K15/00 , B62M6/40
摘要： A reverse horse cart having a treadmill allowing an animal to walk thereon to generate power to run a vehicle. A horse is used as a source of power for a vehicle wherein the horse (or other animal) also rides on the vehicle. To collect energy from the horse in an efficient and ethical matter, the horse will walk on a treadmill causing the belt to rotate a shaft that connects to a flywheel which is communication with a generator. The generator then connects to a tray of capacitors to store the energy. After the energy is stored, the capacitors send the energy to electrical regulators, which pass the electricity to four motors that control each wheel. The motion of the wheels is controlled by a motion logic controller.

33. 发明专利

CA3134417A1 PI4-KINASE INHIBITORS AND METHODS OF USING THE SAME 未知
公开(公告)号：CA3134417A1
公开(公告)日：2020-09-24
申请号：CA3134417
申请日：2020-03-19
申请人： UNIV LELAND STANFORD JUNIOR , GLENN JEFFREY S , SMITH MARK , PHAM EDWARD A , BASU KAUSTABH , STABLER STEPHEN
发明人： GLENN JEFFREY S , SMITH MARK , PHAM EDWARD A , BASU KAUSTABH , STABLER STEPHEN
IPC分类号： C07D401/14 , A61K31/421 , A61K31/427 , A61K31/4439 , A61K31/454 , A61K31/506 , A61P35/00 , C07D233/88 , C07D277/42 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D417/14
摘要： Compounds and methods are provided for inhibiting a PI4-kinase. Methods of treating a pathogen infection and methods of treating cancer are also provided. The PI4-kinase inhibitor can be a compound that is a 5-aryl or heteroaryl-thiazole, e.g., as described herein. In certain embodiments, the PI4-kinase inhibitor is a substituted 2-amino-5-phenylthiazole or substituted 2-amino-5-pyridylthiazole compound. In some embodiments, the compounds have broad spectrum anti-infective activity against a variety of infective diseases, where the diseases are caused by pathogens containing a basic amino acid PIP-2 pincer (BAAPP) domain that interacts with phosphatidylinositol 4,5-bisphosphate (PIP-2) to mediate pathogen replication. Also provided are methods of treating a subject for cancer using a PI4-kinase inhibitor. Aspects of the methods include inhibiting PI4-kinase in a cancer cell to reduce cellular proliferation.

34. 发明专利

CA3102171A1 AUTOMATED HORSE SHOEING APPARATUS AND SYSTEM 未知
公开(公告)号：CA3102171A1
公开(公告)日：2019-12-05
申请号：CA3102171
申请日：2019-06-03
申请人： SMITH MARK
发明人： SMITH MARK
IPC分类号： A01L11/00 , A01L3/00 , A01L15/00
摘要： A system for automated horseshoeing. The system is a three cell concept generally including a tool change area, a gluing area and a modification area. The system generally include a platform for a horse to stand thereon wherein all working components are contained below. The system is configured so that a horse can stand on said platform and the working components move from hoof to hoof thereby allowing the horse to remain in a neutral standing position during the entire shoeing process without having to bend it's ankle. The automated horseshoeing process of the present specification is entirely monitored by a farrier.

35. 发明专利

GB2200549A SHOWER UNIT WITH U.V. LAMPS 未知
公开(公告)号：GB2200549A
公开(公告)日：1988-08-10
申请号：GB8728640
申请日：1987-12-08
申请人： STEVENS SEAN , SMITH MARK
发明人： STEVENS SEAN , SMITH MARK
IPC分类号： A47K3/28 , A61N5/06 , A47K3/22

36. 发明专利

GB191108084A Improvements in Bronzing Machines. 未知
公开(公告)号：GB191108084A
公开(公告)日：1912-03-28
申请号：GB191108084D
申请日：1911-03-31
申请人： SMITH MARK
发明人： SMITH MARK
IPC分类号： B41G1/00
摘要： 8084. Smith, M. March 31. Dropping-roller sheet feeds.-Sheets are fed to a bronzing-machine by a roller G which also acts as a bronze-applying roller, and drops on to the belt C simultaneously with the upward movement of the front stops F, so as to feed the sheet from the table K at the right moment to a carrying- belt C.

37. 发明专利

GB190719042A Improved Method of and Appliances for Placing Insets in Newspapers. 未知
公开(公告)号：GB190719042A
公开(公告)日：1908-03-19
申请号：GB190719042D
申请日：1907-08-24
申请人： SMITH MARK
发明人： SMITH MARK
摘要： 19,042. Smith, M. Aug. 24. Associating-apparatus ; cutting and perforating apparatus ; rotary machines.-In a newspaper-printing machine, insets M' are detached from a roll M, which may have been previously printed and perforated or may be printed and perforated in the machine, by quick-running tapes N, pressed together so as to nip the inset and tear it from the web M at any desired point by an adjustable roller S. The rollers O feed the inset web at the desired speed, which is always slower than that of the main webs A, B, to the detaching means. In some cases the tapes N are run at the slow speed of the rollers O, and the insets are detached by the fast running webs A, B as they pass over the roller C. Additional main webs and inset-supplying devices may be used.

38. 发明专利

GB190524693A Improvements in and relating to Bronzing Machines. 未知
公开(公告)号：GB190524693A
公开(公告)日：1906-08-16
申请号：GB190524693D
申请日：1905-11-29
申请人： SMITH MARK
发明人： SMITH MARK
摘要： 24,693. Smith, M. Nov. 29. Bronzing.-In a bronzing-machine, the cards, sheets of paper, or the like are conveyed by a reciprocating table B from a feed-table beneath the bronzing rollers, pads, &c. J and thence to a delivery table. The reciprocating table may be operated in any suitable manner but, preferably, from a rotary crank C through linkages D, E, G, H. At the lifting of the front stops L on the feed-table, the grippers M seize the sheet and carry it forward, while, at the end of the stroke, the grippers N hold the sheet and, after the table has retreated, drop it on the pile O. During the return stroke of the table, the rollers J are preferably lifted out of contact with it by means of pillars P, reciprocated by the action of eccentrics or cams Q, or, instead, the rollers J are stationary and the table is depressed. B r o n z e powder is largely prevented from escaping from the machine by providing a casing W, and this may be connected to a fan 1 by means of which air is withdrawn from the casing and discharged into a receptacle. The air carries with it the powder. This air and powder may be discharged into a separator 3, the powder falling into the opening T, whence it is fed into the casing by means of a roller U. According to the Provisional Specification, the grippers for taking off the sheet &c. from the table may continue to pull the sheet under the rollers if it has net passed them; also, a band, endless table, or equivalent with a gripping-device may be substituted for the reciprocating table.

39. 发明专利

GB190509164A Improvements in Machines for Fixing Paper Covers on Books 未知
公开(公告)号：GB190509164A
公开(公告)日：1906-03-08
申请号：GB190509164D
申请日：1905-05-02
申请人： SMITH MARK
发明人： SMITH MARK
摘要： 9164. Smith, M. May 2. Glueing.-Paper covers for books are fed on a cylinder between travelling tapes into contact with a glueing, gumming, or pasting wheel which applies a strip of adhesive ; thence they pass under the book, which is pressed against the cover, and the complete book is delivered on to a table. The books to be covered are stored on an inclined table with an adjustable edge L, which projects on a level with the upper surface of the sliding plate P. The covers are fed by hand or mechanically from a table A to the grippers on the cylinder B, over which they pass between two sets of tapes C, D to the glueing-wheel E, which is opposite a groove to prevent the application of glue to the surface of the cylinder B. The covers pass up to an adjustable stop G. The foremost book is then pushed by the plate N on the plate J down on to the cover against the bar O, and is gripped by the forward movement of the plate P. The bar O is moved upwards to press the cover and book close together, and then forwards to allow the book to be passed downwards, drawing the cover away from the tapes, which are supported by the parts R, 0 to prevent distortion. A well-known deliverydevice consisting of sliding rods S and a ribbed plate T delivers the book on to a table. The various parts of the machine are cam-driven from a shaft V through levers and springs, the sliding parts J, S being moved through toothed quadrants and racks.

40. 发明专利

GB190107073A Improvements in Stereotyping Casting Boxes 未知
公开(公告)号：GB190107073A
公开(公告)日：1902-02-06
申请号：GB190107073D
申请日：1901-04-04
申请人： SMITH MARK
发明人： SMITH MARK

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