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31. 发明授权

US10130611B2 Use of benzo-heterocycle derivatives for preventing and treating cancer or for inhibiting cancer metastasis 有权
公开(公告)号：US10130611B2
公开(公告)日：2018-11-20
申请号：US13465709
申请日：2012-05-07
申请人： Sunghoon Kim , Jin Woo Choi , Jin Young Lee , Dae Gyu Kim , Gyoon Hee Han , Jee Sun Yang , Chul Ho Lee
发明人： Sunghoon Kim , Jin Woo Choi , Jin Young Lee , Dae Gyu Kim , Gyoon Hee Han , Jee Sun Yang , Chul Ho Lee
IPC分类号： A61K31/4184 , A61K31/423 , A61K31/428
摘要： This application relates to a novel benzo-heterocycle derivative and more particularly, it relates a composition for preventing and treating cancer or for inhibiting metastasis comprising benzo-heterocycle derivative or pharmaceutically acceptable salts thereof as an active ingredient. The present inventors confirmed that KRS has an effect on cancer metastasis by facilitating cancer (or tumor) cell migration through interaction with 67LR, and also found that a substance inhibiting the interaction between KRS and 67LR can prevent and treat cancer by inhibiting cancer cell metastasis. Accordingly, the composition of the present invention can inhibit cancer metastasis, and thus provide a novel means for prevention and treatment of cancer.

32. 发明授权

US09615078B2 Multi-view video encoding/decoding apparatus and method 有权
公开(公告)号：US09615078B2
公开(公告)日：2017-04-04
申请号：US13994402
申请日：2011-12-13
申请人： Jin Young Lee , Du Sik Park , Ho Cheon Wey
发明人： Jin Young Lee , Du Sik Park , Ho Cheon Wey
IPC分类号： H04N13/00 , H04N19/597 , H04N19/176 , H04N19/147 , H04N19/61 , H04N19/132
CPC分类号： H04N13/161 , H04N19/132 , H04N19/147 , H04N19/176 , H04N19/597 , H04N19/61
摘要： A multi-view video encoding/decoding apparatus and method are provided. The multi-view video encoding/decoding apparatus encodes the current block which is to be encoded and which belongs to a frame of a first view point, wherein the encoding is performed in accordance with a first skip mode using the frame of the first view point or a second skip mode using the frame of a second view point, thereby improving encoding efficiency.

33. 发明授权

US09325558B2 Apparatus and method for providing streaming contents 有权
标题翻译：用于提供流内容的装置和方法
公开(公告)号：US09325558B2
公开(公告)日：2016-04-26
申请号：US13811376
申请日：2011-07-20
申请人： Truong Cong Thang , Jin Young Lee , Seong Jun Bae , Jung Won Kang , Soon Heung Jung , Sang Taick Park , Won Ryu , Jae Gon Kim
发明人： Truong Cong Thang , Jin Young Lee , Seong Jun Bae , Jung Won Kang , Soon Heung Jung , Sang Taick Park , Won Ryu , Jae Gon Kim
IPC分类号： G06F15/16 , H04L29/06 , H04N21/24 , H04N21/44 , H04N21/6543 , H04N21/6547 , G06F12/00 , H04N21/235 , H04N21/238
CPC分类号： H04L67/2804 , H04L29/06027 , H04L47/30 , H04L65/4092 , H04L65/602 , H04L65/604 , H04L65/608 , H04L65/80 , H04N21/2353 , H04N21/23805 , H04N21/2401 , H04N21/2402 , H04N21/44004 , H04N21/6543 , H04N21/6547
摘要： A method and apparatus for an adaptive Hypertext Transfer Protocol (HTTP) streaming service using metadata of content are provided. The metadata may include a minBufferTime attribute indicating a minimum amount of initially buffered media content. A terminal may receive content from a server before playback of the content, and may buffer the content by at least the minimum amount. The metadata may include a range attribute that designates a range of a target indicated by a Uniform Resource Locator (URL). The terminal may receive bytes designated by the range attribute from the URL, and may play back the content using the received bytes.
摘要翻译：提供了一种使用内容元数据的自适应超文本传输协议（HTTP）流传输服务的方法和装置。元数据可以包括指示最初缓冲的媒体内容的最小量的minBufferTime属性。终端可以在播放内容之前从服务器接收内容，并且可以至少缓冲内容的最小量。元数据可以包括指定由统一资源定位符（URL）指示的目标的范围的范围属性。终端可以从URL接收由range属性指定的字节，并且可以使用接收到的字节来播放内容。

34. 发明授权

US08909805B2 Apparatus and method for providing streaming content 有权
标题翻译：用于提供流内容的装置和方法
公开(公告)号：US08909805B2
公开(公告)日：2014-12-09
申请号：US13824995
申请日：2011-10-06
申请人： Truong Cong Thang , Jin Young Lee , Seong Jun Bae , Jung Won Kang , Soon Heung Jung , Sang Taick Park , Won Ryu , Jae Gon Kim
发明人： Truong Cong Thang , Jin Young Lee , Seong Jun Bae , Jung Won Kang , Soon Heung Jung , Sang Taick Park , Won Ryu , Jae Gon Kim
IPC分类号： G06F15/16 , H04N21/61 , H04N21/43 , H04L29/06 , H04N21/235 , H04N21/2343 , H04N21/84 , G06Q90/00 , H04L29/08 , H04N21/845 , H04N21/8541
CPC分类号： H04L65/60 , G06Q90/00 , H04L65/4069 , H04L65/4084 , H04L65/4092 , H04L65/80 , H04L67/02 , H04N21/23439 , H04N21/2358 , H04N21/43 , H04N21/6125 , H04N21/84 , H04N21/845 , H04N21/8541
摘要： A method and apparatus for an adaptive Hypertext Transfer Protocol (HTTP) streaming service using metadata of media content are provided. The media content may include a sequence of one or more periods. The metadata may include a start time attribute and/or a duration attribute of each of the periods. The metadata may determine a start time of each of the periods, and a start time of each of segments included in each of the periods. A terminal may access segments included in each of the periods, may decode and render data of media content included in the segments, and may play back the media content.
摘要翻译：提供了使用媒体内容的元数据的适应性超文本传输协议（HTTP）流传输服务的方法和装置。媒体内容可以包括一个或多个周期的序列。元数据可以包括每个周期的开始时间属性和/或持续时间属性。元数据可以确定每个周期的开始时间和每个周期中包括的每个段的开始时间。终端可以访问包括在每个周期中的段，可以解码和呈现包括在段中的媒体内容的数据，并且可以播放媒体内容。

35. 发明授权

US08877264B2 Composition of skin external application containing ginseng berry extracts 有权
标题翻译：含有人参浆果提取物的外用皮肤成分
公开(公告)号：US08877264B2
公开(公告)日：2014-11-04
申请号：US12602421
申请日：2008-05-30
申请人： Chan Woong Park , Myeong Hoon Yeom , Jin Young Lee , Hee Young Jeon , Sang Jun Lee , Nam Hoon Cho , Dong Sung Lee
发明人： Chan Woong Park , Myeong Hoon Yeom , Jin Young Lee , Hee Young Jeon , Sang Jun Lee , Nam Hoon Cho , Dong Sung Lee
IPC分类号： A61K36/258 , A23L1/30 , A61K8/97 , A61Q19/02 , A61Q19/08
CPC分类号： A23L1/3002 , A23L33/105 , A23V2002/00 , A61K8/97 , A61K36/258 , A61K2800/522 , A61Q19/02 , A61Q19/08 , A23V2250/2124 , A23V2200/318 , A23V2200/332
摘要： Disclosed herein is a. skin external composition containing ginseng berry extract. More specifically, disclosed is a skin external composition, which contains, as an active ingredient, ginseng berry extract having the specific components and compositions, among the above-ground parts of ginseng, and thus promotes the production of collagen in the skin, shows an MMP-I inhibitory effect and, at the same time, has skin-aging inhibitory and wrinkle-reducing effects, resulting from antioxidant effects and DNA damage-protecting effects. Also disclosed is a skin external composition, which contains, as an active ingredient, ginseng berry extract, which has a skin whitening effect resulting from the effects of inhibiting melanin production and reducing pigmentation caused by UV radiation, the effects of relieving dry skin symptoms and atopic symptoms by inducing and maintaining the normal differentiation of skin keratinocytes, the effect of relieving acne and skin troubles by the regulation of sebum secretion and an anti-inflammatory effect, and makes complexion ruddy through the improvement of peripheral blood circulation to make the skin clean and clear. Also disclosed is a food composition for reducing and preventing obesity, which contains, as an active ingredient, ginseng berry extract, which increases the expression of a carnitine palmitoyl transterase-1 (CPT-I) gene, serves to transport fatty acids into mitochondria in fatty acid oxidation and promotes fat oxidation.
摘要翻译：本文公开的是皮肤外用组合物含人参浆果提取物。更具体地，公开了皮肤外用组合物，其含有人参的地上部分中具有特定成分和组成的人参浆果提取物作为活性成分，从而促进皮肤中的胶原蛋白的生成，显示出 MMP-1抑制作用，同时具有由抗氧化作用和DNA损伤保护作用产生的皮肤衰老抑制和皱纹减轻作用。还公开了一种皮肤外用组合物，其含有作为活性成分的人参浆果提取物，其具有由抑制黑色素产生和减少由紫外线辐射引起的色素沉着的作用而产生的皮肤美白效果，减轻干性皮肤症状的效果和通过诱导和维持皮肤角质形成细胞的正常分化，减轻痤疮和皮肤麻烦的作用，通过调节皮脂分泌和抗炎作用而产生特应性症状，并通过改善外周血液循环使肤色变红，使皮肤清洁并清楚还公开了用于减少和预防肥胖的食物组合物，其包含增加肉碱棕榈酰转铁蛋白-1（CPT-1）基因表达的人参浆果提取物作为活性成分，用于将脂肪酸运输到线粒体中脂肪酸氧化并促进脂肪氧化。

36. 发明授权

US08722027B2 Method for preparing broussonetia kazinoki extract 有权
标题翻译：布鲁氏菌提取物的制备方法
公开(公告)号：US08722027B2
公开(公告)日：2014-05-13
申请号：US13704369
申请日：2011-06-15
申请人： Hyung Jun Lim , Jin Young Lee , Sun Young Park , Soon Ae An , Chan Woo Lee , Eun Joo Kim , Jun Oh Kim , Sang Hun Han , Han Kon Kim
发明人： Hyung Jun Lim , Jin Young Lee , Sun Young Park , Soon Ae An , Chan Woo Lee , Eun Joo Kim , Jun Oh Kim , Sang Hun Han , Han Kon Kim
IPC分类号： A61K8/00 , C07C39/12
CPC分类号： A61K8/347 , A61K8/31 , A61K8/34 , A61K8/37 , A61K8/97 , A61K36/60 , A61K2236/00 , A61Q19/02 , C07C29/86 , C07C37/004 , C07C39/21
摘要： The present invention provides a method for preparing a Broussonetia kazinoki extract, comprising the following steps: solvent extracting Broussonetia kazinoki; isolating the Broussonetia kazinoki extract, extracted in the previous step; and crystallizing the Broussonetia kazinoki extract isolated in the previous step. It is possible to prepare a Broussonetia kazinoki extract having a remarkable skin whitening effect and excellent stability through the method for preparing a Broussonetia kazinoki extract.
摘要翻译：本发明提供了一种制备布鲁氏酵母提取物的方法，包括以下步骤：溶剂提取布鲁氏菌属（Broussonetia kazinoki）; 在前一步骤中提取的Broussonetia kazinoki提取物; 并结晶在前一步骤中分离的布鲁氏菌（Broussonetia kazinoki）提取物。通过制备布鲁氏菌（Broussonetia kazinoki）提取物的方法，可以制备具有显着的皮肤美白效果和优异的稳定性的布鲁氏菌（Broussonetia kazinoki）提取物。

37. 发明授权

US08645562B2 Apparatus and method for providing streaming content 有权
标题翻译：用于提供流内容的装置和方法
公开(公告)号：US08645562B2
公开(公告)日：2014-02-04
申请号：US13820955
申请日：2011-09-06
申请人： Truong Cong Thang , Jin Young Lee , Seong Jun Bae , Jung Won Kang , Soon Heung Jung , Sang Taick Park , Won Ryu , Jae Gon Kim
发明人： Truong Cong Thang , Jin Young Lee , Seong Jun Bae , Jung Won Kang , Soon Heung Jung , Sang Taick Park , Won Ryu , Jae Gon Kim
IPC分类号： G06F12/00
CPC分类号： H04L65/608 , H04L29/06027 , H04L65/4084 , H04L65/60 , H04L65/607 , H04N21/2353 , H04N21/23805 , H04N21/2401 , H04N21/44004 , H04N21/6125 , H04N21/84 , H04N21/845 , H04N21/8456
摘要： A method and apparatus for an adaptive Hypertext Transfer Protocol (HTTP) streaming service using metadata of content are provided. The metadata may include one or more BaseURL elements. Uniform Resource Locators (URLs) of segments forming media may be generated based on the BaseURL elements. Additionally, a URL of a segment may be generated by mapping a BaseURL element among the BaseURL elements to a sourceURL attribute of the segment. Segments indicated by generated URLs may be identical to each other.
摘要翻译：提供了一种使用内容元数据的自适应超文本传输协议（HTTP）流传输服务的方法和装置。元数据可以包括一个或多个BaseURL元素。可以基于BaseURL元素生成形成介质的段的统一资源定位符（URL）。另外，可以通过将BaseURL元素中的BaseURL元素映射到该段的sourceURL属性来生成段的URL。生成的URL指示的段可能相同。

38. 发明授权

US08557793B2 Theanine derivative, preparation method thereof, and use thereof for alleviating acne 有权
标题翻译：茶氨酸衍生物及其制备方法及其用于减轻痤疮的用途
公开(公告)号：US08557793B2
公开(公告)日：2013-10-15
申请号：US13816124
申请日：2011-08-09
申请人： Jae Won Yoo , Yu Na Yun , Seo Young Kim , Jin Young Lee , Jun Oh Kim , Jun Cheol Cho
发明人： Jae Won Yoo , Yu Na Yun , Seo Young Kim , Jin Young Lee , Jun Oh Kim , Jun Cheol Cho
IPC分类号： A61K31/715 , A61K31/12 , C13K5/00
CPC分类号： C07H15/12
摘要： The present invention relates to a theanine derivative, a preparation method thereof, and a use thereof for anti-acne treatment, having a selective inhibitory effect on Propionibacterium acnes in the skin.
摘要翻译：本发明涉及对痤疮丙酸杆菌具有选择性抑制作用的抗痤疮治疗用茶氨酸衍生物及其制备方法及其用途。

39. 发明申请

US20130252247A1 KIT FOR SCREENING FOR SKIN-ACTIVATING SUBSTANCES AND COMPRISING THE KLOTHO GENE, AND METHOD FOR SCREENING FOR SKIN-ACTIVATING SUBSTANCES USING THE SAME 审中-公开
标题翻译：用于皮肤激活物质的筛选和包含KLOTHO基因的试剂盒以及使用其进行皮肤激活物质筛选的方法
公开(公告)号：US20130252247A1
公开(公告)日：2013-09-26
申请号：US13881312
申请日：2011-10-28
申请人： Hyang Tae Choi , Eui Dong Son , Jin Young Lee , Yong Joo Na , Ji Hyun Bae
发明人： Hyang Tae Choi , Eui Dong Son , Jin Young Lee , Yong Joo Na , Ji Hyun Bae
IPC分类号： G01N33/50
CPC分类号： G01N33/5044 , C12Q1/6876 , C12Q1/6883 , C12Q2600/148 , C12Q2600/158 , G01N33/5023 , G01N33/6881
摘要： The present invention relates to a kit for screening for skin-activating substances, and to a method for screening for skin-activating substances using same. More particularly, the present invention relates to a kit for screening for skin-activating substances and to a method for screening for skin-activating substances using same, in which candidates for inducing the expression of the klotho gene are separated from skin cells by the screening kit comprising the klotho gene, also known as the anti-aging gene, and the separated candidates are refined, thus screening for skin-activating substances such as moisturizing, anti-aging, or whitening substances.
摘要翻译：本发明涉及用于皮肤激活物质筛选的试剂盒，以及使用该皮肤活化物质的皮肤激活物质的筛选方法。更具体地说，本发明涉及一种用于皮肤激活物质筛选的试剂盒，以及使用该试剂盒筛选皮肤激活物质的方法，其中通过筛选将诱导klotho基因表达的候选物从皮肤细胞分离出来将包含klotho基因（也称为抗衰老基因）的试剂盒和分离的候选物进行精制，从而筛选皮肤活化物质如保湿，抗衰老或增白物质。

40. 发明授权

US08524296B2 Method for fermenting natural materials with salt and fermented extracts prepared therefrom 有权
标题翻译：用盐发酵天然物质的方法和由其制备的发酵提取物
公开(公告)号：US08524296B2
公开(公告)日：2013-09-03
申请号：US12919891
申请日：2009-02-27
申请人： Jun Seong Park , Hye Yoon Park , Jin Young Lee , Eun Joo Kim , Il Young Kwak , Kyung Hee Suh , Duck Hee Kim , Han Kon Kim
发明人： Jun Seong Park , Hye Yoon Park , Jin Young Lee , Eun Joo Kim , Il Young Kwak , Kyung Hee Suh , Duck Hee Kim , Han Kon Kim
IPC分类号： C12G1/00 , A23B7/00 , A61K36/00
CPC分类号： A61K8/97 , A23L7/104 , A23L33/105 , A61K36/75 , A61K36/752 , A61K2800/85 , A61Q19/00 , Y02A50/473
摘要： The present invention relates to a method for fermenting natural products with salt and fermented extracts prepared thereby. The method comprises: adding a predetermined amount of salt to at least one of natural products, including medicinal herbs and cereals; naturally fermenting the salted material; and extracting the fermented salted material with a solvent. Accordingly, the method can prevent the growth of various bacteria, including putrefactive bacteria, E. coli and anaerobic bacteria, which are harmful to the human body, in the natural product, and it also can prevent the generation of bed smells in the natural product. The fermented extract prepared by the method has fewer side effects and is safer than fermented extracts prepared by conventional fermentation methods.
摘要翻译：本发明涉及用盐发酵天然产物的方法和由此制备的发酵提取物。该方法包括：向至少一种天然产物（包括药材和谷物）中加入预定量的盐; 自然发酵盐渍材料; 并用溶剂萃取发酵的盐化物质。因此，该方法可以防止在天然产物中对人体有害的各种细菌，包括腐殖细菌，大肠杆菌和厌氧菌的生长，并且还可以防止在天然产物中产生床气味。通过该方法制备的发酵提取物具有较少的副作用，比通过常规发酵方法制备的发酵提取物更安全。

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