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    • 33. 发明申请
    • Biointerface with macro-and micro-architecture
    • 具有宏观和微观架构的生物界面
    • US20050251083A1
    • 2005-11-10
    • US11055779
    • 2005-02-09
    • Victoria Carr-BrendelPeter SimpsonJames Brauker
    • Victoria Carr-BrendelPeter SimpsonJames Brauker
    • A61F13/00A61L31/10A61L31/14A61L31/16
    • A61L31/10A61L31/146A61L31/16A61L2300/10B33Y80/00
    • Disclosed herein are biointerface membranes including a macro-architecture and a micro-architecture co-continuous with and bonded to and/or located within at least a portion of the macro-architecture. The macro- and micro-architectures work together to manage and manipulate the high-level tissue organization and the low-level cellular organization of the foreign body response in vivo, thereby increasing neovascularization close to a device-tissue interface, interfering with barrier cell layer formation, and providing good tissue anchoring, while reducing the effects of motion artifact, and disrupting the organization and/or contracture of the FBC. The biointerface membranes of the preferred embodiments can be utilized with implantable devices such as devices for the detection of analyte concentrations in a biological sample (for example, from a body), cell transplantation devices, drug delivery devices, electrical signal delivering or measuring devices, and/or combinations thereof.
    • 本文公开的是生物界面膜,其包括宏观架构和与宏结构共同连接并连接到宏结构和/或位于宏观架构的至少一部分内的微架构。 宏观和微观结构共同协调管理和操纵体内异物反应的高级别组织结构和低水平细胞组织,从而增加接近装置 - 组织界面的新生血管形成,干扰屏障细胞层 形成并提供良好的组织锚定,同时减少运动神经的影响,并破坏FBC的组织和/或挛缩。 优选实施方案的生物界面膜可以与可植入装置一起使用,例如用于检测生物样品(例如,来自身体),细胞移植装置,药物递送装置,电信号传送或测量装置中的分析物浓度的装置, 和/或其组合。
    • 36. 发明授权
    • Computer network with a plurality of identically addressed devices
    • 具有多个相同寻址的设备的计算机网络
    • US06301623B1
    • 2001-10-09
    • US09220430
    • 1998-12-24
    • Peter SimpsonKurt BlackerMyles Kimmitt
    • Peter SimpsonKurt BlackerMyles Kimmitt
    • G06F1516
    • H04L41/0893
    • A computer network, and preferably a network concentrator, with a bidirectional serial channel. A plurality of devices on the channel are identified by addresses. The devices are divided into device groups and a device in one group can have an address which is identical to a device in another group. A management processor communicates with the individual devices by digital signaling through an analog multiplexer. The management processor decides which device group to communicate with, and then either generates a selection signal, or sends a data packet to a device register to generate a selection signal which causes the analog multiplexer to connect the bidirectional serial channel of the management processor to the bidirectional serial channel of the proper device group.
    • 具有双向串行信道的计算机网络,并且优选地是网络集中器。 信道上的多个设备由地址标识。 设备分为设备组,一组中的设备可以具有与另一组中的设备相同的地址。 管理处理器通过数字信号通过模拟多路复用器与各个设备进行通信。 管理处理器决定要与哪个设备组进行通信,然后产生选择信号,或者将数据包发送到设备寄存器,以产生选择信号,使得模拟多路复用器将管理处理器的双向串行通道连接到 正确设备组的双向串行通道。