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    • 32. 发明授权
    • Cryogenic probe for NMR microscopy
    • 用于NMR显微镜的低温探针
    • US5258710A
    • 1993-11-02
    • US858924
    • 1992-03-27
    • Robert D. BlackPeter B. RoemerAntonio A. Mogro-CamperoLarry G. Turner
    • Robert D. BlackPeter B. RoemerAntonio A. Mogro-CamperoLarry G. Turner
    • F17C13/00G01R33/31G01R33/34G01R33/20
    • G01R33/34053G01R33/31G01R33/34061G01R33/341G01R33/34007G01R33/34023G01R33/3403
    • An apparatus for microscopic imaging employing nuclear magnetic resonance is constructed from a cryogenic probe which is situated in a conventional magnetic resonance imaging system. The cryogenic probe employs a number of chambers and cryogenic liquids which cool a superconductor resonator to very low temperatures. A sample tube for containing a small specimen is heated to a temperature above its freezing point by flowing nitrogen gas over the specimen. A secondary resonant circuit is inductively coupled to the superconducting resonator. A transceiver passes RF signals to be transmitted into the specimen through the secondary resonant circuit causing the superconducting resonator to transmit the RF signal into the specimen. The resonator then acts as a receive coil and receives a signal from the specimen which is inductively passed to the secondary resonator circuit from which an image is generated. The use of superconductors having low resistance and low temperatures causes noise to be significantly reduced, and the signal-to-noise ratio to be substantially increased.
    • 使用核磁共振的微观成像装置由位于常规磁共振成像系统中的低温探针构成。 低温探针采用多个室和低温液体,将超导体谐振器冷却到非常低的温度。 用于容纳小样本的样品管通过将氮气流过样品而被加热到高于其凝固点的温度。 次级谐振电路感应耦合到超导谐振器。 收发器将RF信号通过次级谐振电路传输到样品中,使超导谐振器将RF信号传输到样品中。 谐振器然后用作接收线圈并且接收来自样品的信号,其被感应地传递到从其产生图像的次级谐振器电路。 使用具有低电阻和低温度的超导体使得噪声显着降低,并且信噪比将显着增加。