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31. 发明申请

US20090171435A1 IMPLANTABLE GRAFT DEVICE HAVING TREATED YARN AND METHOD FOR MAKING SAME 有权
标题翻译：具有处理纱线的可植入纱线装置及其制造方法
公开(公告)号：US20090171435A1
公开(公告)日：2009-07-02
申请号：US12343325
申请日：2008-12-23
申请人： Shyam SV Kuppurathanam , Sean D. Chambers , David P. Biggs , Scott E. EELLS
发明人： Shyam SV Kuppurathanam , Sean D. Chambers , David P. Biggs , Scott E. EELLS
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/075 , A61F2250/0067 , Y10T29/49849
摘要： An implantable graft device having treated yarn is disclosed. The device comprises a graft body forming a lumen defining a longitudinal axis and comprising proximal and distal ends. The graft body comprises a woven fabric having warp yarns aligned in a first direction and a weft yarns aligned in a second direction. At least one of the weft yarns and the warp yarns has an agent applied thereto defining treated yarns of the graft body.
摘要翻译：公开了一种具有经处理的纱线的可植入移植装置。该装置包括形成限定纵向轴线并包括近端和远端的内腔的移植物主体。移植物主体包括具有沿第一方向排列的经纱和沿第二方向排列的纬纱的机织织物。纬纱和经纱中的至少一个具有施加到其上的试剂，其限定了移植物体的经处理的纱线。

32. 发明申请

US20080300610A1 Device for treating hardened lesions and method of use thereof 审中-公开
标题翻译：治疗硬化病变的装置及其使用方法
公开(公告)号：US20080300610A1
公开(公告)日：2008-12-04
申请号：US11809158
申请日：2007-05-31
申请人： Sean D. Chambers
发明人： Sean D. Chambers
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61B17/320725 , A61B2017/00539 , A61B2017/00778 , A61B2017/22061 , A61M2025/0057 , A61M2025/1013 , A61M2025/105 , A61M2025/1061 , A61M2025/1086 , A61M2025/109
摘要： A balloon catheter is provided that may be used to dilate hardened regions of a stenosis on a vessel wall. The balloon catheter is provided with cutting elements that extend along a surface of a balloon. At least one bioactive is present, either on the cutting element, within the interior of the balloon, within the material of the balloon or on an outside surface of the balloon. The bioactive is delivered to the vessel wall upon dilation of the balloon.
摘要翻译：提供了可用于扩张血管壁上的狭窄硬化区域的球囊导管。气囊导管设置有沿气球表面延伸的切割元件。在切割元件上，在球囊的内部，气囊的材料内或气球的外表面上存在至少一种生物活性物质。气球膨胀后，生物活性物质被传送到血管壁。

33. 发明申请

US20130018220A1 METHOD FOR ELECTROSPINNING A GRAFT LAYER 有权
标题翻译：电镀层的方法
公开(公告)号：US20130018220A1
公开(公告)日：2013-01-17
申请号：US13548956
申请日：2012-07-13
申请人： Siddharth U. Vad , Mark A. Magnuson , Mark R. Frye , Sean D. Chambers
发明人： Siddharth U. Vad , Mark A. Magnuson , Mark R. Frye , Sean D. Chambers
IPC分类号： A61F2/06
CPC分类号： A61L31/041 , A61F2/07 , B29C47/0014 , B29C47/0064 , B29C47/06 , B29K2075/00 , B29K2083/00 , B29L2009/00 , B29L2023/20 , B29L2031/7546 , B32B2250/03 , D01D5/0038 , D01D5/0069 , D01D5/0084 , D04H1/728 , D04H3/073
摘要： A method for making a graft layer is provided. The graft layer has at least two layers with different porosities. The two layers are applied by electrospinning. The parameters of the electrospinning may be varied when applying the first and second layers in order to achieve different porosities of the first and second layers.
摘要翻译：提供了制备接枝层的方法。接枝层具有至少两层具有不同孔隙率的层。通过静电纺丝应用两层。当施加第一和第二层以便实现第一和第二层的不同孔隙率时，静电纺丝的参数可以变化。

34. 发明申请

US20120330402A1 HELICAL STENT 审中-公开
标题翻译：螺丝刀
公开(公告)号：US20120330402A1
公开(公告)日：2012-12-27
申请号：US13530685
申请日：2012-06-22
申请人： Siddharth U. Vad , Mark R. Frye , Sean D. Chambers
发明人： Siddharth U. Vad , Mark R. Frye , Sean D. Chambers
IPC分类号： A61F2/88 , A61F2/06
CPC分类号： A61F2/88 , A61F2/07 , A61F2/89 , A61F2220/0075 , A61F2240/001
摘要： A helical stent is provided that is wound in a zig-zag pattern along a pitch angle with respect to a plane transverse to the axis of the stent. A bisecting line extending through a bend and between two adjacent angular struts is also angled with respect to the longitudinal axis of the stent.
摘要翻译：提供螺旋支架，其以相对于支架的轴线的平面的俯仰角以锯齿形图案缠绕。延伸穿过弯曲部并且在两个相邻角撑杆之间的平分线也相对于支架的纵向轴线成角度。

35. 发明授权

US08187316B2 Implantable graft device having treated yarn and method for making same 有权
标题翻译：具有处理纱线的可植入移植装置及其制造方法
公开(公告)号：US08187316B2
公开(公告)日：2012-05-29
申请号：US12343325
申请日：2008-12-23
申请人： Shyam S V Kuppurathanam , Sean D. Chambers , David P. Biggs , Scott E. Eells
发明人： Shyam S V Kuppurathanam , Sean D. Chambers , David P. Biggs , Scott E. Eells
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/075 , A61F2250/0067 , Y10T29/49849
摘要： An implantable graft device having treated yarn is disclosed. The device includes a graft body forming a lumen defining a longitudinal axis and having proximal and distal ends. The graft body is constructed from a woven fabric having warp yarns aligned in a first direction and a weft yarns aligned in a second direction. At least one of the weft yarns and the warp yarns has an agent applied thereto defining treated yarns of the graft body.
摘要翻译：公开了一种具有经处理的纱线的可植入移植装置。该装置包括形成限定纵向轴线并具有近端和远端的内腔的移植物体。移植物主体由具有沿第一方向排列的经纱和沿第二方向排列的纬纱的机织织物构成。纬纱和经纱中的至少一个具有施加到其上的试剂，其限定了移植物体的经处理的纱线。

36. 发明申请

US20100016881A1 BIODEGRADABLE FILTER 审中-公开
标题翻译：可生物降解过滤器
公开(公告)号：US20100016881A1
公开(公告)日：2010-01-21
申请号：US12174160
申请日：2008-07-16
申请人： BRUCE R. FLECK , Sean D. Chambers , Jacob Lund Clausen , Per Hendriksen , Blayne A. Roeder
发明人： BRUCE R. FLECK , Sean D. Chambers , Jacob Lund Clausen , Per Hendriksen , Blayne A. Roeder
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2002/016 , A61F2210/0004 , A61F2230/005 , A61F2230/008
摘要： A medical device that filters thrombi in a body vessel is disclosed. After the need for filtering passes, the device maintains patency in the body vessel without requiring additional steps of percutaneous retrieval or introduction into the patient.
摘要翻译：公开了一种在身体容器中过滤血栓的医疗装置。在需要过滤之后，该装置在身体血管中保持通畅，而不需要额外的经皮检索或引入患者的步骤。

37. 发明授权

US10271974B2 Helical stent 有权
公开(公告)号：US10271974B2
公开(公告)日：2019-04-30
申请号：US13530685
申请日：2012-06-22
申请人： Siddharth U. Vad , Mark R. Frye , Sean D. Chambers
发明人： Siddharth U. Vad , Mark R. Frye , Sean D. Chambers
IPC分类号： A61F2/88 , A61F2/07 , A61F2/89
摘要： A helical stent is provided that is wound in a zig-zag pattern along a pitch angle with respect to a plane transverse to the axis of the stent. A bisecting line extending through a bend and between two adjacent angular struts is also angled with respect to the longitudinal axis of the stent.

38. 发明申请

US20120211120A1 IMPLANTABLE GRAFT DEVICE HAVING TREATED YARN AND METHOD FOR MAKING SAME 有权
标题翻译：具有处理纱线的可植入纱线装置及其制造方法
公开(公告)号：US20120211120A1
公开(公告)日：2012-08-23
申请号：US13457949
申请日：2012-04-27
申请人： Shyam SV Kuppurathanam , Sean D. Chambers , David P. Biggs , Scott E. Eells
发明人： Shyam SV Kuppurathanam , Sean D. Chambers , David P. Biggs , Scott E. Eells
IPC分类号： D03C13/00
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/075 , A61F2250/0067 , Y10T29/49849
摘要： An implantable graft device having treated yarn is disclosed. The device comprises a graft body forming a lumen defining a longitudinal axis and comprising proximal and distal ends. The graft body comprises a woven fabric having warp yarns aligned in a first direction and a weft yarns aligned in a second direction. At least one of the weft yarns and the warp yarns has an agent applied thereto defining treated yarns of the graft body.
摘要翻译：公开了一种具有经处理的纱线的可植入移植装置。该装置包括形成限定纵向轴线并包括近端和远端的内腔的移植物主体。移植物主体包括具有沿第一方向排列的经纱和沿第二方向排列的纬纱的机织织物。纬纱和经纱中的至少一个具有施加到其上的试剂，其限定了移植物体的经处理的纱线。

39. 发明申请

US20120060348A1 TWO-STAGE METHOD OF COMPRESSING A STENT 有权
标题翻译：压缩方法的两阶段方法
公开(公告)号：US20120060348A1
公开(公告)日：2012-03-15
申请号：US13322091
申请日：2010-05-21
申请人： Sean D. Chambers , Mark A. Magnuson , Fred T. Parker
发明人： Sean D. Chambers , Mark A. Magnuson , Fred T. Parker
IPC分类号： B23P11/00
CPC分类号： A61F2/95 , A61F2/958 , A61F2002/9522 , Y10T29/49908
摘要： A two-stage method of compressing a stent entails providing an expandable stent (100,105) in a radially expanded state. An outward pressure is applied to an inner surface of the tubular framework to support the stent, and a diameter of the stent is reduced to a first compressed diameter (D1) while applying the outward pressure. The outward pressure is halted after reaching the first compressed diameter. According to an embodiment in which the stent is balloon-expandable, a delivery balloon catheter (130) comprising an uninflated balloon in a delivery configuration is inserted into the lumen after halting the outward pressure. The diameter of the stent is reduced to a second compressed diameter (D2) smaller than the first compressed diameter to crimp the stent onto the delivery balloon catheter.
摘要翻译：压缩支架的两级方法需要提供处于放大状态的可扩张支架（100,105）。向管状框架的内表面施加向外的压力以支撑支架，并且在施加向外的压力的同时将支架的直径减小到第一压缩直径（D1）。达到第一压缩直径后，向外的压力停止。根据其中支架是球囊可膨胀的实施例，包括具有输送构型的未膨胀气囊的输送气囊导管（130）在停止向外的压力之后插入腔内。支架的直径减小到小于第一压缩直径的第二压缩直径（D2），以将支架卷曲到输送球囊导管上。

40. 发明申请

US20110270177A1 Device for Treating Hardened Lesions 有权
标题翻译：治疗硬化病变的装置
公开(公告)号：US20110270177A1
公开(公告)日：2011-11-03
申请号：US13130420
申请日：2008-12-01
申请人： Sean D. Chambers , Steen Aggerholm , Joe Horn
发明人： Sean D. Chambers , Steen Aggerholm , Joe Horn
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61B17/320725 , A61B2017/00539 , A61B2017/00778 , A61B2017/22061 , A61M2025/0057 , A61M2025/1013 , A61M2025/105 , A61M2025/1061 , A61M2025/1086 , A61M2025/109
摘要： A balloon catheter is provided that may be used to dilate hardened regions of a stenosis on a vessel wall. The balloon catheter is provided with cutting elements that extend along a surface of a balloon. At least one bioactive is present, either on the cutting element, within the interior of the balloon, within the material of the balloon or on an outside surface of the balloon. The bioactive is delivered to the vessel wall upon dilation of the balloon.
摘要翻译：提供了可用于扩张血管壁上的狭窄硬化区域的球囊导管。气囊导管设置有沿气球表面延伸的切割元件。在切割元件上，在球囊的内部，气囊的材料内或气球的外表面上存在至少一种生物活性物质。气球膨胀后，生物活性物质被传送到血管壁。

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