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31. 发明申请

US20110208047A1 Multi-Dose Injection System 失效
标题翻译：多剂量注射系统
公开(公告)号：US20110208047A1
公开(公告)日：2011-08-25
申请号：US13126210
申请日：2009-10-22
申请人： Frank M. Fago
发明人： Frank M. Fago
IPC分类号： A61B6/00
CPC分类号： A61M5/14546 , A61B6/548 , A61M5/007 , A61M5/1407 , A61M5/1413 , A61M5/14216 , A61M5/1456 , A61M5/162 , A61M5/16827 , A61M5/445 , A61M39/08 , A61M2005/14553 , A61M2205/12 , A61M2205/121 , A61M2205/3653 , A61M2205/6054
摘要： A multi-dose injection system (108) is disclosed that allows for safe and easy use of bulk containers, a multi-use tubing set (110), and syringes (86a, 86b) across multiple patients. The bulk containers may include a saline bottle (118) and a contrast bottle (120) for administration to a series of patients undergoing imaging procedures. The bottles (118, 120) may be fluidly connected to a cassette (114) that includes a saline valve (176) and a contrast valve (178) operable to control flow from the saline bottle (118) and the contrast bottle (120), respectively. The cassette (114) may be fluidly interconnected to the multi-use tubing set (110) that is, in turn, fluidly connected to syringes (86a, 86b) on a powerhead (50) and a patient-specific tubing set (112). The patient-specific tubing set (112) may be replaced between patients and may also serve to isolate the remainder of the multi-dose injection system (108) from contamination from bodily fluids.
摘要翻译：公开了一种多剂量注射系统（108），其允许跨多个患者安全和容易地使用散装容器，多用途管组（110）和注射器（86a，86b）。散装容器可以包括盐水瓶（118）和造影剂瓶（120），用于给经历成像程序的一系列患者施用。瓶子（118,120）可以流体地连接到包括盐水阀（176）和对比阀（178）的盒（114），该对比阀可操作以控制从盐水瓶（118）和对比瓶（120）的流动，，分别。盒（114）可以流体地互连到多用管组（110），所述多用管组（110）又流体地连接到动力头（50）和患者专用管组（112）上的注射器（86a，86b）。患者特异性管组（112）可以在患者之间替换，并且还可以用于将多剂量注射系统（108）的其余部分与体液污染隔离。

32. 发明申请

US20110137160A1 Power Injector with Decay Constant Functionality 审中-公开
标题翻译：功率放大器，具有衰减常数功能
公开(公告)号：US20110137160A1
公开(公告)日：2011-06-09
申请号：US12810149
申请日：2009-08-18
申请人： Frank M. Fago , Alya Schalabi
发明人： Frank M. Fago , Alya Schalabi
IPC分类号： A61B6/00
CPC分类号： A61M5/007 , A61B6/032 , A61B6/481 , A61B6/548 , A61M5/14546 , A61M2005/14208 , A61M2005/14553 , G06F19/321 , G06F19/3468 , G16H20/17 , G16H30/20
摘要： A power injector (154) is disclosed that may utilize decay constant determination logic (192). This logic (192) in turn may incorporate a test injection protocol (194). The test injection protocol (194) may be executed to acquire data for the derivation of a flow rate decay constant. The derived flow rate decay constant may be used by the power injector (154) to execute of an injection protocol (162), for instance in conjunction with an operation of an imaging unit (152) for an imaging operation.
摘要翻译：公开了可以利用衰减常数确定逻辑（192）的动力注射器（154）。该逻辑（192）又可以包含测试注入协议（194）。可以执行测试注入协议（194）以获取用于推导流量衰减常数的数据。动力注射器（154）可以使用导出的流速衰减常数来执行注射协议（162），例如结合用于成像操作的成像单元（152）的操作。

33. 发明授权

US07918009B2 Methods of using radiopharmaceutical pigs 有权
标题翻译：使用放射性药物猪的方法
公开(公告)号：US07918009B2
公开(公告)日：2011-04-05
申请号：US12486489
申请日：2009-06-17
申请人： Frank M. Fago , Matt Bantly , David W. Wilson
发明人： Frank M. Fago , Matt Bantly , David W. Wilson
IPC分类号： B23P11/00 , G21F5/00 , G21F5/018
CPC分类号： A61M5/1785 , A61J1/16 , A61M5/007 , G21F5/015 , G21F5/018 , Y10T29/4998 , Y10T29/49982
摘要： A pharmaceutical pig is used to transport a syringe containing a liquid radiopharmaceutical from a radiopharmacy to a medical facility for administration to a patient. The pharmaceutical pig includes an elongate polymer cap that is removably attached to an elongate polymer base. The elongate polymer cap includes a cap shell that completely encloses a cap shielding element and the elongate polymer base includes a base shell that completely encloses a base shielding element. Preferably the polymer utilized for the cap shell and the base shell is polycarbonate resin, e.g., LEXAN®. An inner liner is not utilized and the cap shielding element and the base shielding element, which are preferably, but not necessarily, made of lead, are completely sealed and unexposed.
摘要翻译：使用制药猪将含有液体放射性药物的注射器从放射性药物运送到医疗设施以给予患者。制药猪包括细长聚合物盖，其可拆卸地连接到细长聚合物基底。细长聚合物盖包括完全包围帽屏蔽元件的帽壳，细长聚合物基底包括完全包围基底屏蔽元件的基底壳。用于盖壳和基壳的聚合物优选为聚碳酸酯树脂，例如LEXAN。不利用内衬，并且盖屏蔽元件和基本屏蔽元件（其优选但不必须由铅构成）被完全密封和未曝光。

34. 发明申请

US20100274126A1 Fluid Driven Medical Injectors 有权
公开(公告)号：US20100274126A1
公开(公告)日：2010-10-28
申请号：US12830542
申请日：2010-07-06
申请人： Gary S. Wagner , Frank M. Fago , Peter Staats , Dane Battiato
发明人： Gary S. Wagner , Frank M. Fago , Peter Staats , Dane Battiato
IPC分类号： A61B6/00 , A61M5/31
CPC分类号： A61B5/055 , A61M5/007 , A61M5/14216 , A61M5/14228 , A61M5/14526 , A61M5/1454 , A61M5/16827 , A61M39/08 , A61M2005/14513
摘要： Some injectors of the invention may include a fluid drive responsive to pressure of a working fluid (e.g., liquid, pneumatic, or both) to impart a sequence of forces to drive a delivery device (e.g., a syringe) to deliver a medical fluid (e.g., a contrast agent, a radiopharmaceutical, a drug, or a combination thereof). Some injectors may include a multimedia tube configured to pass a working fluid (e.g., air) and a light signal (e.g., infrared). Some injectors may include a peristaltic drive responsive to pressure of a working fluid.

35. 发明申请

US20100051135A1 CONTRAST CONTAINER HOLDER AND METHOD TO FILL SYRINGES 有权
标题翻译：对比容器夹持器和灌装方法
公开(公告)号：US20100051135A1
公开(公告)日：2010-03-04
申请号：US12617558
申请日：2009-11-12
申请人： Frank M. Fago , Robert G. Bergen , James F. Farmer
发明人： Frank M. Fago , Robert G. Bergen , James F. Farmer
IPC分类号： B65B3/04
CPC分类号： A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/1782 , A61M2209/082
摘要： The filling of a syringe can be performed at a faster rate using a filling sequence which expels air from the fill tube before filling the syringe. A similar method is used when changing contrast containers during a filling sequence to ensure that all the air is expelled from the fill tube before filling resumes with the new contrast container. Additionally, by including a contrast container holder that is affixed to an injector head and holds the container near the syringe tip, the filling sequence can be accomplished without requiring the operator to hold the contrast container during the sequence.
摘要翻译：注射器的填充可以使用在填充注射器之前从填充管排出空气的填充顺序以更快的速率进行。当在填充顺序期间改变对比剂容器时，使用类似的方法以确保在用新的对比容器填充恢复之前所有空气都从填充管排出。此外，通过包括固定到注射器头部并将容器保持在注射器末端附近的造影剂容器保持器，可以实现填充顺序，而不需要操作者在顺序期间保持造影剂容器。

36. 发明申请

US20090278062A1 METHODS OF USING RADIOPHARMACEUTICAL PIGS 有权
标题翻译：使用放射性核素的方法
公开(公告)号：US20090278062A1
公开(公告)日：2009-11-12
申请号：US12486489
申请日：2009-06-17
申请人： Frank M. Fago , Matt Bantly , David W. Wilson
发明人： Frank M. Fago , Matt Bantly , David W. Wilson
IPC分类号： G21F3/00
CPC分类号： A61M5/1785 , A61J1/16 , A61M5/007 , G21F5/015 , G21F5/018 , Y10T29/4998 , Y10T29/49982
摘要： A pharmaceutical pig is used to transport a syringe containing a liquid radiopharmaceutical from a radiopharmacy to a medical facility for administration to a patient. The pharmaceutical pig includes an elongate polymer cap that is removably attached to an elongate polymer base. The elongate polymer cap includes a cap shell that completely encloses a cap shielding element and the elongate polymer base includes a base shell that completely encloses a base shielding element. Preferably the polymer utilized for the cap shell and the base shell is polycarbonate resin, e.g., LEXAN®. An inner liner is not utilized and the cap shielding element and the base shielding element, which are preferably, but not necessarily, made of lead, are completely sealed and unexposed.
摘要翻译：使用制药猪将含有液体放射性药物的注射器从放射性药物运送到医疗设施以给予患者。制药猪包括细长聚合物盖，其可拆卸地连接到细长聚合物基底。细长聚合物盖包括完全包围帽屏蔽元件的帽壳，细长聚合物基底包括完全包围基底屏蔽元件的基底壳。用于盖壳和基壳的聚合物优选为聚碳酸酯树脂，例如LEXAN。不利用内衬，并且盖屏蔽元件和基本屏蔽元件（其优选但不必须由铅构成）被完全密封和未曝光。

37. 发明申请

US20080237502A1 System and Method of Identifying Eluant Amounts Supplied to a Radioisotope Generator 审中-公开
标题翻译：识别向放射性同位素发生器提供的洗脱液量的系统和方法
公开(公告)号：US20080237502A1
公开(公告)日：2008-10-02
申请号：US11995727
申请日：2006-07-26
申请人： Frank M. Fago
发明人： Frank M. Fago
IPC分类号： G21F5/015 , A61N5/00
CPC分类号： G21F5/018 , G21G4/08
摘要： The invention, is directed to a system including a shielded container (16), a radioisotope generator disposed within the shielded container, and an elution supply mechanism. The elution supply mechanism may include an eluant supply container (4) at least partially external to the shielded container (16), a conduit (10) extending between an inlet (20) of the radioisotope generator and an outlet (6, 8) of the eluant supply container, and an eluant visualization portal.
摘要翻译：本发明涉及一种包括屏蔽容器（16），设置在屏蔽容器内的放射性同位素发生器和洗脱供给机构的系统。洗脱供给机构可以包括至少部分地在屏蔽容器（16）外部的洗涤剂供应容器（4），在放射性同位素发生器的入口（20）之间延伸的导管（10）和出口（6,8）洗脱液供应容器和洗脱液可视化门户。

38. 发明申请

US20080033368A1 SYSTEMS AND METHODS FOR MANAGING INFORMATION RELATING TO MEDICAL FLUIDS AND CONTAINERS THEREFOR 审中-公开
标题翻译：用于管理与其流体和容器有关的信息的系统和方法
公开(公告)号：US20080033368A1
公开(公告)日：2008-02-07
申请号：US11617953
申请日：2006-12-29
申请人： Frank M. Fago
发明人： Frank M. Fago
IPC分类号： A61M5/00
CPC分类号： A61M5/14546 , A61B6/4494 , A61M5/1456 , A61M5/14566 , A61M5/16827 , A61M5/1785 , A61M2005/14553 , A61M2205/17 , A61M2205/3569 , A61M2205/6054 , G06F19/3462 , G06F19/3468 , G16H40/40
摘要： The present invention relates to management of information relating to medical fluids, containers therefor, and medical fluid administration devices for administering such medical fluids to patients. Data tags (e.g., RFID tags) are generally associated with containers of the invention and may be electromagnetically read from and/or written to using an electromagnetic device, for example, that may be associated with a medical fluid administration device of the invention.
摘要翻译：本发明涉及与医用流体及其容器相关的信息的管理，以及用于向患者施用这种医用流体的医用流体管理装置。数据标签（例如，RFID标签）通常与本发明的容器相关联，并且可以使用电磁装置进行电磁读取和/或写入，所述电磁装置例如可与本发明的药液管理装置相关联。

39. 发明授权

US06871087B1 Suspension device and method 失效
标题翻译：悬架装置及方法
公开(公告)号：US06871087B1
公开(公告)日：2005-03-22
申请号：US09513087
申请日：2000-02-25
申请人： Michael Scott Hughes , William Hagen , Mark Boyce , Frank M. Fago
发明人： Michael Scott Hughes , William Hagen , Mark Boyce , Frank M. Fago
IPC分类号： A61M5/00 , A61M5/14 , A61M5/145 , A61B6/00
CPC分类号： A61M5/1409 , A61M5/007 , A61M5/1452
摘要： A device and method for providing a suspended agent such as a contrast agent without mechanical resuspension. A volume of agent is divided into sub-volumes in a network of tubes, cells, sponges, grooves, etc. A propellant fluid flows through the network to release the suspended agent. The network may be internal to a container for the propellant fluid. Alternatively, the network may be adjacent an exit port of a container for the propellant fluid, or may be in-line between a propellant fluid container and a patient. The invention reduces sedimentation of agents into one or a few aggregates and eliminates a mechanical mixing step. The invention thus provides a uniformly suspended agent, improving patient health and safety and increasing cost and time savings.
摘要翻译：一种用于提供悬浮剂如造影剂的装置和方法，而无机械再悬浮。试剂的体积在管，细胞，海绵，槽等网络中分成子体积。推进剂流体流过网络以释放悬浮剂。该网络可以在用于推进剂流体的容器的内部。或者，网络可以邻近用于推进剂流体的容器的出口，或者可以在推进剂流体容器和患者之间成直线。本发明减少了试剂沉淀成一个或几个聚集体，并消除了机械混合步骤。因此，本发明提供均匀悬浮剂，改善患者的健康和安全性并增加成本和时间节省。

40. 发明授权

US5279569A Front loading apparatus for insecting fluid into animals 失效
标题翻译：用于将动物流入动物的前装载装置
公开(公告)号：US5279569A
公开(公告)日：1994-01-18
申请号：US881782
申请日：1992-05-11
申请人： Charles Neer , Frank M. Fago , Paul E. Dieterlen , James H. Goethel
发明人： Charles Neer , Frank M. Fago , Paul E. Dieterlen , James H. Goethel
IPC分类号： A61D7/00 , A61M5/145 , A61M1/00 , A61M5/00
CPC分类号： A61M5/14546 , A61M2250/00 , A61M5/14566 , A61M5/1458 , Y10S128/01
摘要： An animal fluid injector, replaceable syringe and method of replacement of the syringe in the injector are provided in which the syringe is loadable and unloadable into and from the injector through the open front end of a pressure jacket of the injector, thereby permitting replacement without retraction of the syringe plunger drive or disconnection of the injection tubing. The syringe is provided with a pressure restraining front end, such as an integral or removable cap with structure such as threads that lock the syringe to the front end of the jacket by mating with threads on the jacket. A mechanism in the injector, which includes, for example, a key on cam ring operated by a lever with one hand of an operator, interacts with structure such asymmetrically spaced notches on the back end of the syringe to, for example, rotate the syringe and simultaneously translate or rotate a coupling on the syringe plunger into and out of engagement with the plunger drive in the injector.
摘要翻译：提供动物流体注射器，可替换的注射器和注射器中更换注射器的方法，其中注射器可通过注射器的压力套的敞开的前端装载和卸载注射器，从而允许更换而不缩回注射器柱塞驱动或注射管的断开。注射器设置有压力限制前端，例如具有诸如螺纹的结构的整体或可移除的盖，其通过与护套上的螺纹配合将注射器锁定到护套的前端。注射器中的机构，其包括例如由操作者的一只手操作的杠杆操作的凸轮环上的键与注射器后端上的这种不对称间隔的凹口的结构相互作用，例如旋转注射器并且同时将注射器柱塞上的联接器平移或旋转进入注射器中的柱塞驱动器并与其脱离接合。

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