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31. 发明申请

US20060148803A1 Substituted peptides useful in the treatment of alzheimer's disease 审中-公开
标题翻译：可用于治疗阿尔茨海默病的取代肽
公开(公告)号：US20060148803A1
公开(公告)日：2006-07-06
申请号：US10532285
申请日：2003-10-21
申请人： James Beck
发明人： James Beck
IPC分类号： A61K31/519 , A61K31/502 , A61K31/498 , A61K31/4745 , A61K31/165
CPC分类号： A61K31/165 , A61K31/38 , A61K31/44 , A61K31/4745 , A61K31/495 , A61K31/498 , A61K31/502 , A61K31/519
摘要： Disclosed are methods for treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of compounds of formula (I), wherein Ar, W, Z, Q, R1, U, and L, are as herein defined.
摘要翻译：公开了通过使用式（I）的化合物治疗阿尔茨海默病和/或抑制β-分泌酶的方法和/或抑制Aβ肽在哺乳动物中的沉积，其中Ar，W，Z Q，R 1，U和L如本文所定义。

32. 发明申请

US20050138544A1 Viewing system that supports multiple electronic document types 有权
标题翻译：查看支持多种电子文档类型的系统
公开(公告)号：US20050138544A1
公开(公告)日：2005-06-23
申请号：US10743660
申请日：2003-12-22
申请人： James Beck , Kelly Dolan , William Ross , Gregory Zelesnik
发明人： James Beck , Kelly Dolan , William Ross , Gregory Zelesnik
IPC分类号： G06F17/00
CPC分类号： G06F17/2785
摘要： A method of interpreting electronic documents, e.g., an interactive technical manual, provides an interpreter responsive to at least one global navigational input data of a client user in order to generate a displayable output. The displayable output is generated from informational input and a contextual status. The method of interpretation includes a base semantics module and any number of extended semantics modules, a symbol table, and an output module. A plurality of global navigational data are received at the interpreter, which associates and processes the informational data received with the contextual status and outputs displayable data which is renderable by the display system into a current view. A system and computer medium are also disclosed.
摘要翻译：解释电子文档（例如交互式技术手册）的方法提供响应于客户端用户的至少一个全局导航输入数据的解释器，以产生可显示的输出。可显示的输出是从信息输入和上下文状态生成的。解释方法包括基本语义模块和任意数量的扩展语义模块，符号表和输出模块。在解释器处接收多个全局导航数据，其将接收的信息数据与上下文状态相关联并处理，并将可由显示系统呈现的可显示数据输出到当前视图中。还公开了一种系统和计算机介质。

33. 发明申请

US20050000457A1 Method for the development of ruminant feed formulations 失效
标题翻译：反刍动物饲料配方的开发方法
公开(公告)号：US20050000457A1
公开(公告)日：2005-01-06
申请号：US10867877
申请日：2004-06-15
申请人： James Beck
发明人： James Beck
IPC分类号： A01K1/10 , C12N20060101
CPC分类号： A23K50/10 , A23K10/30
摘要： A method that accounts for environmental factors by measuring the starch and fiber degradation characteristics of a variety of genetically different crop plants and grain from crop plants in real time to determine how the crop plants should be conserved, processed and blended into a feed formulation that results in optimum productivity of the ruminant animal. A method further including determining starch digestibility characteristics of a set of crop plant samples comprising grain of said crop plant; developing a prediction equation based on said starch digestibility characteristics, obtaining a grain sample from a crop plant, determining in real time starch digestibility characteristics by NIRS of said sample by inputting data from said NIRS into said equation, storing and/or milling said grain on an identity preserved basis, and determining the amount of said crop plant to incorporate into a feed formulation based on the starch digestibility characteristics.
摘要翻译：通过从实际测量各种遗传上不同的作物和谷物的淀粉和纤维降解特征来确定作物如何被保守，加工和混合成饲料配方，从而解释环境因素的方法，其结果在反刍动物的最佳生产力。一种进一步包括确定一组作物植物样品的淀粉消化率特征的方法，所述作物植物样品包含所述作物植物的颗粒; 基于所述淀粉消化率特征开发预测方程，从作物植物获得谷物样品，通过将所述NIRS的数据输入所述方程式来实时测定所述样品的NIRS的淀粉消化率特征，将所述颗粒存储和/或研磨基于身份保存的基础，以及基于淀粉消化性特征确定所述作物植物掺入饲料制剂的量。

34. 发明授权

US08311797B2 Viewing system that supports multiple electronic document types 有权
标题翻译：查看支持多种电子文档类型的系统
公开(公告)号：US08311797B2
公开(公告)日：2012-11-13
申请号：US12126237
申请日：2008-05-23
申请人： James Beck , Kelly Dolan , William Ross , Gregory Zelesnik
发明人： James Beck , Kelly Dolan , William Ross , Gregory Zelesnik
IPC分类号： G06F17/28
CPC分类号： G06F17/2785
摘要： A method of interpreting electronic documents, e.g., an interactive technical manual, provides an interpreter responsive to at least one global navigational input data of a client user in order to generate a displayable output. The displayable output is generated from informational input and a contextual status. The method of interpretation includes a base semantics module and any number of extended semantics modules, a symbol table, and an output module. A plurality of global navigational data are received at the interpreter, which associates and processes the informational data received with the contextual status and outputs displayable data which is renderable by the display system into a current view. A system and computer medium are also disclosed.
摘要翻译：解释电子文档（例如交互式技术手册）的方法提供响应于客户端用户的至少一个全局导航输入数据的解释器，以产生可显示的输出。可显示的输出是从信息输入和上下文状态生成的。解释方法包括基本语义模块和任意数量的扩展语义模块，符号表和输出模块。在解释器处接收多个全局导航数据，其将接收的信息数据与上下文状态相关联并处理，并将可由显示系统呈现的可显示数据输出到当前视图中。还公开了一种系统和计算机介质。

35. 发明申请

US20120208187A1 Method and Kit for Determining Severity and Progression of Periodontal Disease 审中-公开
标题翻译：确定牙周病严重程度和进展的方法和试剂盒
公开(公告)号：US20120208187A1
公开(公告)日：2012-08-16
申请号：US13316198
申请日：2011-12-09
申请人： Kenneth Kornman , Xiaodong Wu , Hwa-Ying Wang , Steven Offenbacher , James Beck , John Rogus
发明人： Kenneth Kornman , Xiaodong Wu , Hwa-Ying Wang , Steven Offenbacher , James Beck , John Rogus
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q1/6827 , C12Q2600/118 , C12Q2600/156 , C12Q2600/172 , G01N2800/18
摘要： An improved method and kit of determining whether a patient is predisposed to having severe periodontal disease and/or having high risk of progression of periodontal disease, comprising the steps of (i) taking a biological sample from said patient; (ii) genotyping said biological sample for genetic polymorphism pattern comprising IL 1B (rs16944), IL 1B (rs1143623) and IL 1B (rs4848306); and (iii) comparing said genetic polymorphism patterns to a reference composite genotype pattern; wherein the similarity of said genetic polymorphism patterns to said reference pattern indicate said patient's predisposition to having severe periodontal disease and/or having high risk of progression of periodontal disease.
摘要翻译：一种改进的方法和试剂盒，用于确定患者是否倾向于具有严重的牙周疾病和/或具有高风险的牙周病，包括以下步骤：（i）从所述患者取得生物样品; （ii）对包含IL 1B（rs16944），IL 1B（rs1143623）和IL 1B（rs4848306）的遗传多态性模式的所述生物样品进行基因分型; 和（iii）将所述遗传多态性模式与参考复合基因型模式进行比较; 其中所述遗传多态性模式与所述参考模式的相似性指示所述患者患有严重牙周疾病和/或具有高牙周病进展风险的倾向。

36. 发明申请

US20110019595A1 METHODS AND APPARATUS TO RETROFIT WIRED HEALTHCARE AND FITNESS SYSTEMS FOR WIRELESS OPERATION 有权
标题翻译：改造有线卫生和健康系统进行无线操作的方法和装置
公开(公告)号：US20110019595A1
公开(公告)日：2011-01-27
申请号：US12739519
申请日：2008-10-23
申请人： Surendar Magar , Louis Yun , James Beck , Ali Niknejad
发明人： Surendar Magar , Louis Yun , James Beck , Ali Niknejad
IPC分类号： H04B7/14 , H04B3/36
CPC分类号： A61B5/0026 , A61B5/0002 , A61B5/0006 , A61B5/0024 , A61B5/0031 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B2560/0412 , H04B7/026 , H04B7/04 , H04W4/18 , H04W88/04
摘要： Provided herein is an apparatus for converting a wired sensor system to a wireless sensor system. The apparatus can comprise a relay station comprising at least one antenna and at least one radio. The relay station can be adaptable to be integrated as at least one application specific integrated circuit and further adaptable to convert a wired sensor system into a wireless sensor system. Further provided are systems for converting wired sensor systems into wireless sensor systems and methods of use.
摘要翻译：本文提供了一种用于将有线传感器系统转换成无线传感器系统的装置。该装置可以包括包括至少一个天线和至少一个无线电的中继站。中继站可以适用于集成为至少一个专用集成电路，并且还可适应于将有线传感器系统转换成无线传感器系统。还提供了用于将有线传感器系统转换成无线传感器系统和使用方法的系统。

37. 发明授权

US07451077B1 Acoustic presentation system and method 有权
标题翻译：声学演示系统及方法
公开(公告)号：US07451077B1
公开(公告)日：2008-11-11
申请号：US10711526
申请日：2004-09-23
申请人： Felicia Lindau , Chuck Wooters , James Beck
发明人： Felicia Lindau , Chuck Wooters , James Beck
IPC分类号： G10L19/00
CPC分类号： G10L21/06
摘要： Complex acoustic information, such as music, is presented as visual information or as movement of an object in a manner simulating the reception of the complex acoustic information by the human auditory system including a complexity of tempo, rhythms, intensity variation from highs to lows, and silences of the audio, providing a synchronicity with these characteristics. The acoustic information is processed by an acoustic human-like auditory transformation. The transformation may be varied depending on the presentation controlled by the device. The transformed signal is then applied to a tactile or visual presentation. The audience reception of the invention is through light, color, or animation of an image or object complementing the reception of the acoustic information.
摘要翻译：诸如音乐的复杂声学信息被呈现为视觉信息或以模拟由听觉系统接收复杂声学信息的方式的对象的移动，包括节奏，节奏，从高到低的强度变化的复杂度，和静音，提供与这些特征的同步性。声学信息由声学人类听觉变换处理。转换可以根据由设备控制的显示而变化。然后将变换的信号应用于触觉或视觉呈现。本发明的观众接收是通过补充声音信息的接收的图像或对象的光，颜色或动画。

38. 发明申请

US20080222521A1 Viewing System that Supports Multiple Electronic Document Types 有权
标题翻译：支持多种电子文档类型的查看系统
公开(公告)号：US20080222521A1
公开(公告)日：2008-09-11
申请号：US12126237
申请日：2008-05-23
申请人： James Beck , Kelly Dolan , William Ross , Gregory Zelesnik
发明人： James Beck , Kelly Dolan , William Ross , Gregory Zelesnik
IPC分类号： G06F3/14
CPC分类号： G06F17/2785
摘要： A method of interpreting electronic documents, e.g., an interactive technical manual, provides an interpreter responsive to at least one global navigational input data of a client user in order to generate a displayable output. The displayable output is generated from informational input and a contextual status. The method of interpretation includes a base semantics module and any number of extended semantics modules, a symbol table, and an output module. A plurality of global navigational data are received at the interpreter, which associates and processes the informational data received with the contextual status and outputs displayable data which is renderable by the display system into a current view. A system and computer medium are also disclosed.
摘要翻译：解释电子文档（例如交互式技术手册）的方法提供响应于客户端用户的至少一个全局导航输入数据的解释器，以产生可显示的输出。可显示的输出是从信息输入和上下文状态生成的。解释方法包括基本语义模块和任意数量的扩展语义模块，符号表和输出模块。在解释器处接收多个全局导航数据，其将接收的信息数据与上下文状态相关联并处理，并将可由显示系统呈现的可显示数据输出到当前视图中。还公开了一种系统和计算机介质。

39. 发明申请

US20060194966A1 Substituted aminoethers for the treatment of alzheimer's disease 失效
标题翻译：用于治疗阿尔茨海默氏病的取代氨基醚
公开(公告)号：US20060194966A1
公开(公告)日：2006-08-31
申请号：US10527294
申请日：2003-09-10
申请人： James Beck , Matthew Drowns , Martha Warpehoski
发明人： James Beck , Matthew Drowns , Martha Warpehoski
IPC分类号： C07D279/12 , C07D241/04 , C07D281/02
CPC分类号： C07C233/78 , C07C237/34 , C07C255/57 , C07C2601/02 , C07D213/30 , C07D213/81 , C07D239/26 , C07D263/32 , C07D277/30 , C07D413/04
摘要： The invention provides compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
摘要翻译：本发明提供式（I）化合物：可用于治疗阿尔茨海默病和其他类似疾病。这些化合物包括β-分泌酶的抑制剂，其可用于治疗阿尔茨海默病和以哺乳动物中Aβ肽沉积为特征的其它疾病。本发明的化合物可用于降低Aβ肽形成的药物组合物和治疗方法。

40. 发明申请

US20060188873A1 Method for detecting a target polynucleotide 审中-公开
标题翻译：检测靶多核苷酸的方法
公开(公告)号：US20060188873A1
公开(公告)日：2006-08-24
申请号：US11246287
申请日：2005-10-11
申请人： Andreas Abel , James Beck , Markus Ehrat , Peter Oroszlan
发明人： Andreas Abel , James Beck , Markus Ehrat , Peter Oroszlan
IPC分类号： C12Q1/70 , C12Q1/68 , C12M1/34 , G02B6/00
CPC分类号： C12Q1/682 , C12Q1/6825 , C12Q2565/607 , C12Q2537/125 , C12Q2565/501
摘要： A method of detecting a target polynucleotide using a solution phase nucleic acid sandwich assay, wherein the solid support is an optical planar waveguide, and the label is detected by measuring the luminescence that is excited in the evanescent field of the waveguide-A fully automated system may be used. The method may be of use in detecting nucleic acids associated with disease at very low concentrations.
摘要翻译：使用溶液相核酸夹心测定法检测靶多核苷酸的方法，其中固体支持物是光学平面波导，并且通过测量在波导-A全自动系统的消逝场中激发的发光来检测标记可能用过了。该方法可用于以非常低的浓度检测与疾病相关的核酸。

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