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31. 发明授权

US06430300B1 Cooling mechanism for an audio speaker 有权
标题翻译：音频扬声器的冷却机构
公开(公告)号：US06430300B1
公开(公告)日：2002-08-06
申请号：US09404451
申请日：1999-09-22
申请人： Brian Cox , Aaron Linn , Leif Blackmon
发明人： Brian Cox , Aaron Linn , Leif Blackmon
IPC分类号： H04R2500
CPC分类号： H04R9/022
摘要： A cooling mechanism is provided for an audio speaker, which mechanism includes a plate of a thermally conductive material mounted between the driver mechanism of the speaker and the speaker basket and extending from the voice coil gap to the outside of the speaker. The spacing between this plate and the voice coil is preferably kept as small as possible. The plate is preferably a vent plate having a plurality of radial vents extending along the width of the plate from the voice coil gap side thereof to the side facing the outside of the speaker. Such a vent plate, in addition to providing radiant cooling, also provides cooling via air flow as well as conduction and convection cooling. The vents are sized and shaped so as to minimize any turbulence, and thus any audible air noise.
摘要翻译：提供了一种用于音频扬声器的冷却机构，该机构包括安装在扬声器的驱动器机构和扬声器篮之间并且从音圈间隙延伸到扬声器外部的导热材料的板。该板和音圈之间的间隔优选保持尽可能小。板最好是排气板，其具有沿板的宽度从其音圈间隙侧向面向扬声器外侧的一侧延伸的多个径向通风口。除了提供辐射冷却之外，这样的排气板还通过空气流以及传导和对流冷却来提供冷却。通风口的尺寸和形状被设计成最小化任何湍流，从而使任何可闻的空气噪音最小化。

32. 发明授权

US06426337B1 2-(Purin-9-yl)-tetrahydrofuran-3,4-diol derivatives 有权
标题翻译： 2-（嘌呤-9-基） - 四氢呋喃-3,4-二醇衍生物
公开(公告)号：US06426337B1
公开(公告)日：2002-07-30
申请号：US09331526
申请日：1999-08-20
申请人： Brian Cox , Suzanne Elaine Keeling , David George Allen , Alison Judith Redgrave , Michael David Barker , Heather Hobbs , Thomas Davis Roper, IV , Joanna Victoria Geden
发明人： Brian Cox , Suzanne Elaine Keeling , David George Allen , Alison Judith Redgrave , Michael David Barker , Heather Hobbs , Thomas Davis Roper, IV , Joanna Victoria Geden
IPC分类号： A61K3170
CPC分类号： C07D473/00 , C07H19/16 , Y10S514/826 , Y10S514/851 , Y10S514/885 , Y10S514/921 , Y10S514/925
摘要： There are provided according to the invention novel compounds of formula (I) wherein R1, R2, and R3 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
摘要翻译：根据本发明提供新的式（I）化合物，其中R 1，R 2和R 3如说明书中所述，其制备方法，含有它们的制剂及其在治疗炎性疾病中的用途。

33. 发明申请

US20170318200A1 ELECTRONIC DEVICE SUCH AS A WIRELESS SECURITY CAMERA HAVING WALL-MOUNTED AND STAND-ALONE MODES 审中-公开
公开(公告)号：US20170318200A1
公开(公告)日：2017-11-02
申请号：US15582326
申请日：2017-04-28
申请人： Brian Cox , Robert Chong
发明人： Brian Cox , Robert Chong
IPC分类号： H04N5/225 , H04N7/18 , H04N5/232 , H02J7/02
CPC分类号： H04N5/2252 , H02J7/02 , H04N5/2257 , H04N5/23206 , H04N5/23245 , H04N5/23296 , H04N5/33 , H04N7/183
摘要： A wireless security camera has both a wall-mounted mode and a standalone mode. In wall-mounted mode, the camera is much more unobtrusive than prior cameras. In standalone mode, the camera is aesthetically pleasing and does not look out of place.

34. 发明申请

US20120016705A1 METHOD AND APPARATUS FOR SUPPORTING A COMPUTER-BASED PRODUCT 审中-公开
标题翻译：支持基于计算机的产品的方法和装置
公开(公告)号：US20120016705A1
公开(公告)日：2012-01-19
申请号：US13260244
申请日：2009-07-02
申请人： Dejan S. Milojicic , Brian Cox , Timothy F. Forell , Alan G. Nemeth , Peter Piet
发明人： Dejan S. Milojicic , Brian Cox , Timothy F. Forell , Alan G. Nemeth , Peter Piet
IPC分类号： G06Q10/00
CPC分类号： G06Q10/06 , G06Q10/04 , G06Q10/063 , G06Q10/06375 , G06Q30/016
摘要： A technique includes providing a cost model to predict a total cost for supporting a computer-based product system. The cost model predicts preventive, reactive and deferred components of the total cost. The technique includes determining features of the support and computer-based product system based at least in part on the cost model.
摘要翻译：一种技术包括提供成本模型来预测支持基于计算机的产品系统的总成本。成本模型预测总成本的预防性，反应性和延迟性成分。该技术包括至少部分地基于成本模型确定支持和基于计算机的产品系统的特征。

35. 发明授权

US07998990B2 5-phenyl-thiazol-2-yl-urea derivatives and use as PI3 kinase inhibitors 失效
标题翻译： 5-苯基 - 噻唑-2-基 - 脲衍生物，用作PI3激酶抑制剂
公开(公告)号：US07998990B2
公开(公告)日：2011-08-16
申请号：US12227315
申请日：2007-05-21
申请人： Emma Budd , Judy Fox Hayler , Ian Bruce , Darren Mark Legrand , Brian Cox
发明人： Emma Budd , Judy Fox Hayler , Ian Bruce , Darren Mark Legrand , Brian Cox
IPC分类号： A61K31/426 , C07D277/42
CPC分类号： C07D277/48 , C07D417/12
摘要： The present invention concerns a compound of formula Ia wherein: Ra* is hydrogen or C1-C4-alkyl; Rb* is —(C1-C4-alkylene)-Y—C1-C4-haloalkyl or —(C1-C4-alkylene)-Y—C1-C4-hydroxyalkyl; Y represents —CONH— or a five membered heteroaryl group. R2* is C1-C4-alkyl or halogen; R3* is halo, —SO2—CH3, —SO2—CF3, carboxy, —CO—NH2, —CO-di(C1-C8-alkyl)amino, or a 5- or 6-membered heterocyclic ring having one or more ring hetero atoms selected from the group consisting of oxygen, nitrogen and sulphur, that ring being optionally substituted by halo, cyano, oxo, hydroxy, carboxy, nitro, C3-C8-cycloalkyl, C1-C8-alkylcarbonyl, C1-C8-alkoxy optionally substituted by aminocarbonyl, or C1-C8-alkyl optionally substituted by hydroxy, C1-C8-alkoxy, C1-C8-alkylamino or di(C1-C8-alkyl)amino; R4* is hydrogen, halo, —SO2—CH3, nitrile, C1-C8-haloalkyl, imidazolyl, C1-C8-alkyl, —NR8*R9*, or —SO2—NR8*R9*; and R5* is hydrogen, halogen or C1-C8-alkyl; R8* and R9* are independently hydrogen, amino, C1-C8-alkylamino, di(C1-C8-alkyl)amino, or CC1-C8-alkyl optionally substituted by hydroxyl; or a pharmaceutically acceptable salt, or solvate thereof, to compositions and use of the compounds in the treatment of diseases ameliorated by inhibition of phosphatidylinositol 3-kinase.
摘要翻译：本发明涉及式Ia化合物，其中：Ra *是氢或C 1 -C 4 - 烷基; Rb *是 - （C1-C4-亚烷基）-Y-C1-C4-卤代烷基或 - （C1-C4-亚烷基）-Y-C1-C4-羟基烷基; Y表示-CONH-或五元杂芳基。 R2 *是C1-C4-烷基或卤素; R3 *是卤素，-SO2-CH3，-SO2-CF3，羧基，-CO-NH2，-CO-二（C1-C8-烷基）氨基或具有一个或多个环的5-或6-元杂环氰基，氧代，羟基，羧基，硝基，C 3 -C 8 - 环烷基，C 1 -C 8 - 烷基羰基，任选地被C 1 -C 8 - 烷氧基取代的C 1 -C 8 - 烷氧基被氨基羰基取代，或任选被羟基，C 1 -C 8 - 烷氧基，C 1 -C 8 - 烷基氨基或二（C 1 -C 8 - 烷基）氨基取代的C 1 -C 8烷基; R4 *是氢，卤素，-SO2-CH3，腈，C1-C8-卤代烷基，咪唑基，C1-C8-烷基，-NR8 * R9 *或-SO2-NR8 * R9 * 和R5 *是氢，卤素或C1-C8-烷基; R 8 *和R 9 *独立地为氢，氨基，C 1 -C 8 - 烷基氨基，二（C 1 -C 8 - 烷基）氨基或任选被羟基取代的C 1 -C 8 - 烷基; 或其药学上可接受的盐或溶剂合物，用于治疗通过抑制磷脂酰肌醇3-激酶而改善的疾病的组合物和用途。

36. 发明授权

US07806049B2 Kit for creating artistic work on lawn 有权
标题翻译：在草坪上创作艺术作品的工具包
公开(公告)号：US07806049B2
公开(公告)日：2010-10-05
申请号：US12339004
申请日：2008-12-18
申请人： Riley C. Fields , Brian Cox , Daniel Lee Bizzell
发明人： Riley C. Fields , Brian Cox , Daniel Lee Bizzell
IPC分类号： B05C17/06
CPC分类号： B44D2/007 , A01G2/00 , B44D2/002 , G09F19/228
摘要： Components of a kit for creating an artistic work on a lawn include: a container of aerosol paint; a plurality of stakes for anchoring a lawn stencil to a lawn; and a sheet of flexible material in which is defined one or more openings used to apply one or more design elements of the artistic work to the lawn by spraying the aerosol paint through the one or more openings in the lawn stencil when the lawn stencil is anchored to the lawn with the stakes. The components are held in a container having a relatively small form factor that readily accommodates point-of-sale display and purchase at retail stores by consumers.
摘要翻译：用于在草坪上创作艺术作品的工具包的组成部分包括：气溶胶漆容器; 用于将草坪模板锚定到草坪的多个桩; 以及一片柔性材料，其中限定了一个或多个开口，用于通过在草坪模板被锚定时通过草坪模板中的一个或多个开口喷射气溶胶涂料将一个或多个艺术作品的设计元素施加到草坪上到草坪与赌注。这些部件被保持在具有相对小的形状因素的容器中，该容器容易地容纳消费者在零售商店的销售点显示和购买。

37. 发明申请

US20090131457A1 Pyrazolo [3,4-D] Pyrimidine Derivatives Useful to Treat Respiratory Disorders 审中-公开
标题翻译：吡唑并[3,4-D]嘧啶衍生物可用于治疗呼吸系统疾病
公开(公告)号：US20090131457A1
公开(公告)日：2009-05-21
申请号：US12227314
申请日：2007-05-21
申请人： Ian Bruce , Judy Fox Hayler , Graham Charles Bloomfield , Lee Edwards , Brian Cox , Catherine Howsham
发明人： Ian Bruce , Judy Fox Hayler , Graham Charles Bloomfield , Lee Edwards , Brian Cox , Catherine Howsham
IPC分类号： A61K31/519 , C07D487/04 , A61P11/06
CPC分类号： A61K31/519 , A61K31/5377 , C07D487/04
摘要： The present invention concerns a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, where R1-R3 and Y are defined in the description, and its use in the treatment of disorders in which pi3 kinase is implicated.
摘要翻译：本发明涉及式（I）化合物或其药学上可接受的盐或溶剂合物，其中R1-R3和Y在说明书中定义，及其用于治疗其中涉及pi3激酶的病症。

38. 发明授权

US07334518B2 Kits for creating artistic works on residential lawns 有权
标题翻译：用于在住宅草坪上创作艺术作品的工具包
公开(公告)号：US07334518B2
公开(公告)日：2008-02-26
申请号：US11163888
申请日：2005-11-02
申请人： Brian Cox , Riley C. Fields , Daniel Lee Bizzell
发明人： Brian Cox , Riley C. Fields , Daniel Lee Bizzell
IPC分类号： B05C17/06
CPC分类号： B44D2/002 , A01G2/00 , B44D2/007
摘要： A kit for creating an artistic work on a residential lawn includes: first and second lawn stencils; first and second containers of paint of first and second colors; and a plurality of stakes. The stakes are used to anchor the lawn stencils to the lawn, and the paint is used to apply layers of paint over the lawn stencils, which in turn applies layers of the paint in desired patterns on the lawn. Each lawn stencil includes a pattern of openings therein, which pattern corresponds to one or more design elements of the artwork to be applied to the lawn using the paint. Additional lawn stencils and containers of paint also may be included in this aspect. Proper orientation of each lawn stencil of the kit is insured by proper orientation and alignment of an indication of orientation and alignment locations, which each lawn stencil includes.
摘要翻译：用于在住宅草坪上创作艺术作品的工具包括：第一和第二草坪模板; 第一和第二种颜色的第一和第二容器; 和多个桩。这些赌注用于将草坪模板固定在草坪上，油漆用于在草坪模板上涂上一层油漆，而这些油漆模板依次在草坪上施加所需图案的油漆层。每个草坪模板包括其中的开口图案，该图案对应于使用涂料施加到草坪上的艺术品的一个或多个设计元素。附加的草坪模板和油漆容器也可能包括在这方面。套件的每个草坪模板的正确定位通过适当的取向和对准每个草坪模板所包括的取向和对准位置的指示来保证。

39. 发明申请

US20080015541A1 Embolectomy Catheters And Methods For Treating Stroke And Other Small Vessel Thromboembolic Disorders 有权
标题翻译：用于治疗中风和其他小血管栓塞性疾病的结肠切除术导管和方法
公开(公告)号：US20080015541A1
公开(公告)日：2008-01-17
申请号：US11773601
申请日：2007-07-05
申请人： Robert Rosenbluth , George Green , Brian Cox , Thomas Sternweiler , Sean Chow , Richard Monetti
发明人： Robert Rosenbluth , George Green , Brian Cox , Thomas Sternweiler , Sean Chow , Richard Monetti
IPC分类号： A61M25/10
CPC分类号： A61B17/22032 , A61B17/135 , A61B17/221 , A61B2017/22034 , A61B2017/22044 , A61B2017/22077 , A61B2017/22084 , A61B2017/22094 , A61B2017/2212 , A61B2017/320716 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/008 , A61F2230/0091 , A61M2025/0042 , A61M2025/0183
摘要： Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing clots or other obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable with or over a guidewire which has been pre-inserted through or around the clot. Also, in some embodiments, the embolectomy catheters include clot removal devices which are deployable from the catheter after the catheter has been advanced at least partially through the clot. The clot removal device may include a deployable wire nest that is designed to prevent a blood clot from passing therethrough. The delivery catheter may include telescoping inner and outer tubes, with the clot removal device being radially constrained by the outer tube. Retraction of the outer tube removes the constraint on the clot removal device and permits it to expand to its deployed configuration. An infusion guidewire is particularly useful in conjunction with the embolectomy catheter, and permits infusion of medicaments or visualization fluids distal to the clot.
摘要翻译：用于从血管中去除凝块或其他阻塞物（例如，血栓，血栓栓塞，动脉粥样硬化斑块的栓塞碎片，异物等）的系统和方法，快速交换微导管。本发明特别可用于在脑卒中或脑缺血期间经皮去除血栓栓塞或其他来自脑小血管的阻塞物质。在一些实施例中，本发明的止血栓塞导管可以在已经插入穿过凝块或围绕凝块的导丝上或之上前进。此外，在一些实施例中，止血管切除导管包括在导管至少部分地穿过血块前进之后可从导管展开的凝块移除装置。凝块移除装置可以包括被设计成防止血块从其中通过的可展开的线巢。输送导管可以包括伸缩的内管和外管，其中血块去除装置由外管径向约束。外管的收缩消除了对凝块去除装置的约束，并允许其扩展到其部署构型。输注导丝特别适用于结肠切除术导管，并且可以输送远离凝块的药物或可视化液体。

40. 发明申请

US20070176333A1 VASCULAR EMBOLIZATION WITH AN EXPANSIBLE IMPLANT 有权
标题翻译：具有可扩展植入物的血管嵌合
公开(公告)号：US20070176333A1
公开(公告)日：2007-08-02
申请号：US11733697
申请日：2007-04-10
申请人： George Greene , Robert Rosenbluth , Brian Cox
发明人： George Greene , Robert Rosenbluth , Brian Cox
IPC分类号： B28B3/00
CPC分类号： A61L31/146 , A61B17/12022 , A61B17/12113 , A61B17/12186 , A61B17/1219 , A61B34/10 , A61B2017/00526 , A61B2017/1205 , A61F2/06 , A61L31/145 , A61L31/18 , A61L2430/36 , B33Y50/00 , B33Y80/00 , Y10S623/901 , Y10S623/903 , Y10T29/49
摘要： A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site. Upon entering the vascular site, the implant expands in situ substantially to fill the vascular site. A retention element is contained within the microcatheter and has a distal end detachably connected to the implant. A flexible, tubular deployment element is used to pass the implant and the retention element through the microcatheter, and then to separate the implant from the retention element when the implant has been passed out of the microcatheter and into the vascular site.
摘要翻译：由可压缩泡沫材料形成的血管植入物具有压缩构型，其可膨胀到基本上符合要栓塞的血管部位的形状和尺寸的构造。优选地，植入物由亲水的大孔泡沫材料形成，具有血管部位的缩小模型的初始构型，从而可压缩成压缩构型。通过扫描血管部位来创建植入物以产生数字化的扫描数据集; 使用扫描数据集创建血管部位的三维数字化虚拟模型; 使用虚拟模型创建血管部位的缩小物理模具; 并使用模具以血管部位的缩小模型的形式产生血管植入物。为了栓塞血管部位，植入物被压缩并通过微导管，其远端已经进入血管部位。在进入血管部位时，植入物基本上扩张以填充血管部位。保持元件容纳在微导管内并且具有可拆卸地连接到植入物的远端。使用柔性的管状展开元件将植入物和保持元件通过微导管，然后当植入物从微导管通过并进入血管部位时，将植入物与保留元件分离。

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