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    • 35. 发明申请
    • Method and apparatus for detecting nucleic acid data
    • 检测核酸数据的方法和装置
    • US20050079501A1
    • 2005-04-14
    • US10502513
    • 2003-01-24
    • Hisashi KoikeTomonori NagaokaTakatomo SatohYoshioki KanekoMidori HatanakaMorinao FukuokaHiroko SakamotoHiroyuki Yonekawa
    • Hisashi KoikeTomonori NagaokaTakatomo SatohYoshioki KanekoMidori HatanakaMorinao FukuokaHiroko SakamotoHiroyuki Yonekawa
    • C12N15/09C12Q1/68G01N33/50G01N33/53G01N33/566G01N33/58
    • C12Q1/6827C12Q1/6837C12Q2565/501C12Q2561/12C12Q2527/107
    • That invention provides a nucleic acid information detection method which, in a method wherein a target nucleic acid, and probes having a complementary sequence with at least a portion of the target nucleic acid sequence, are contacted with each other in order to form hybrids between the target nucleic acid and the probes, and the amount of signal generated depending on the amount of hybrids is measured in order to detect the information on the target nucleic acid, includes kinetically obtaining data of the signal. Furthermore the invention provides a nucleic acid information detection method which, in a method wherein a perfect matched probe having a perfect complementary sequence with respect to at least part of a target nucleic acid sequence, and one or more types of imperfectly matched probes having at least one part of the perfect matched probe mutated, are contacted with the target nucleic acid in order to hybridize between the target nucleic acid and the perfect matched probe, or the imperfect matched probes, so that the information on the target nucleic acid can be detected based on the difference in binding strength of the hybrids, includes kinetically obtaining data of the signal while changing continuously or stepwise the condition for measuring or detecting the signal from the hybrids.
    • 本发明提供了一种核酸信息检测方法,其方法是使靶核酸和与靶核酸序列的至少一部分具有互补序列的探针彼此接触,以形成混合物 靶核酸和探针,并且测量根据杂交体量产生的信号量,以便检测关于靶核酸的信息,包括动态获得信号的数据。 此外,本发明提供了一种核酸信息检测方法,其方法中,其中完全匹配的探针具有相对于目标核酸序列的至少一部分具有完全互补序列,以及一种或多种不完全匹配的探针,其至少具有至少 突变的完美匹配探针的一部分与目标核酸接触以便在靶核酸和完全匹配的探针之间进行杂交,或者不完全匹配的探针,使得可以基于目标核酸的信息被检测 关于混合物的结合强度的差异,包括动态获得信号的数据,同时连续或逐步地改变用于测量或检测来自杂交体的信号的条件。
    • 36. 发明授权
    • Ink cartridge
    • 墨盒
    • US06302530B1
    • 2001-10-16
    • US08881644
    • 1997-06-24
    • Kazumichi ShimadaHideki OikawaHisashi MiyazawaYoshie KumagaiTakao KobayashiHisashi Koike
    • Kazumichi ShimadaHideki OikawaHisashi MiyazawaYoshie KumagaiTakao KobayashiHisashi Koike
    • B41J2175
    • B41J2/17553B41J2/17513B41J2/17523
    • In accordance with the invention, in order to increase the volume of an ink cartridge containing color inks, to prevent the ink cartridge from being improperly mounted on a print head, to ensure that required rigidity of an ink cartridge, and to ensure the viscosities of different inks remain uniform, in an ink cartridge body, a plurality of ink chambers are arranged in at least two linear arrays, and ink supplying ports associated with the ink chambers are also arranged in two linear arrays, whereby the size of the ink cartridge can be reduced, and easy loading of the ink cartridge can be insured. Additionally, the ink supply ports may be arranged in a zig-zag, offset manner to allow for a further reduction in the size of the ink chambers and ink cartridge. The open outer ends of the ink supply ports are formed substantially flush with the bottom walls of the ink chambers. Therefore, the volumes of each of the ink chambers is increased. Further, at least one or the like is provided on the outside of the ink cartridge, to insure the strength and rigidity of the ink cartridge. Circuitous grooves are formed in the surface of a cover member so that the grooves communicating with ink chambers having a smaller volumes are longer than grooves communicating with ink chambers having larger volumes, thus insuring uniform viscosities of all of the inks.
    • 根据本发明,为了增加含有彩色墨水的墨盒的体积,为了防止墨盒被错误地安装在打印头上,以确保墨盒所需的刚性,并且确保墨盒的粘度 不同的油墨保持均匀,在墨盒主体中,多个墨室布置在至少两个线性阵列中,并且与墨室相关联的供墨口也布置成两个线性阵列,由此墨盒的尺寸可以 减少,并且可以保证墨盒的容易装载。 另外,供墨口可以以锯齿形的偏移方式布置,以允许进一步减小墨室和墨盒的尺寸。 供墨口的敞开的外端形成为与油墨室的底壁基本齐平。 因此,每个墨室的体积增加。 此外,在墨盒的外侧设置至少一个等,以确保墨盒的强度和刚性。 在盖构件的表面中形成有凹槽,使得与具有较小体积的墨室连通的凹槽比与具有较大体积的墨室连通的凹槽更长,从而确保所有油墨均匀的粘度。
    • 37. 发明授权
    • Ink cartridge and loading mechanism for ink cartridge
    • 墨盒的墨盒和装载机构
    • US06250750B1
    • 2001-06-26
    • US08888936
    • 1997-07-07
    • Hisashi MiyazawaTakao KobayashiHisashi KoikeHitoshi IgarashiMasanori Yoshida
    • Hisashi MiyazawaTakao KobayashiHisashi KoikeHitoshi IgarashiMasanori Yoshida
    • B41J2175
    • B41J2/17513B41J2/1752B41J2/17553
    • Reinforcing ridges are formed so as to project from corner portions of peripheral walls, and an opening end edge is made thick-walled, so that an ink cartridge having a sufficient rigidity can be molded using vapor impermeable soft synthetic resins. In addition, shape keeping ribs are formed so as to project from the outer sides of longitudinal ribs that are formed on an inner surface of a cover body, so that deformation of the cartridge can be suppressed during vibration welding. Further, an engaging recess arranged in a lower surface of an ink cartridge is adapted to receive a support rod of an ink cartridge loading mechanism. A carriage cover body of the loading mechanism is closed as a lifter is guided with a guide groove which is parallel to the axial center of an ink supply needle so that the ink cartridge is allowed to descend correctly toward a recording head, so that the ink cartridge can be loaded correctly without breaking the ink supply needle.
    • 形成隆起凸起以从周壁的角部突出,并且开口端缘被制成厚壁,从而可以使用不透气的软合成树脂来模制具有足够刚性的墨盒。 此外,形状保持肋形成为从形成在盖体的内表面上的纵向肋的外侧突出,使得在振动焊接期间可以抑制盒的变形。 此外,布置在墨盒的下表面中的接合凹槽适于容纳墨盒装载机构的支撑杆。 装载机构的托架盖主体被关闭,因为升降机被引导与导向槽平行,所述引导槽平行于供墨针的轴心,使得墨盒被允许正确地向记录头下降,使得墨水 墨盒可以正确装入,不会损坏墨水供应针。