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31. 发明申请

US20100113789A1 MEDICINAL COMPOSITION FOR PREVENTION OR TREATMENT OF PARASITIC PROTOZOAN INFECTION 有权
标题翻译：用于预防或治疗PARASITIC PROTOZOAN感染的药物组合物
公开(公告)号：US20100113789A1
公开(公告)日：2010-05-06
申请号：US11576429
申请日：2005-09-30
申请人： Masataka Ihara , Kiyosei Takasu , Khanitha Pudhom , Hiroshi Kitaguchi , Masayuki Kawakami , Kozo Sato
发明人： Masataka Ihara , Kiyosei Takasu , Khanitha Pudhom , Hiroshi Kitaguchi , Masayuki Kawakami , Kozo Sato
IPC分类号： C07D417/14
CPC分类号： C07D277/84 , A61K31/427 , A61K31/428 , A61K31/4439 , A61K31/4709 , C07D277/64 , C07D417/14 , Y02A50/409 , Y02A50/411 , Y02A50/414
摘要： The present invention is to provide a medicinal composition for preventing or treating parasitic protozoan infections, having a high selective toxicity against parasitic protozoan infection, and a superior preventive or treating effect. A medicinal composition for preventing or treating parasitic protozoan infections comprises a compound shown by the following general formula (1) as an active ingredient (wherein R represents an alkyl group, aryl group or heterocyclic group; A and B each independently represents a 5- or 6-membered ring containing at least one hetero atom, or a condensation ring wherein 1 or more 3- to 8-membered ring is condensed thereto; Y represents S, O, Se, or —NR1— (R1 represents an alkyl group, aryl group or heterocyclic group); L1, L2, L3, L4 and L5 each independently represents a methine group; Q represents a physiologically acceptable anion; k represents an integer of 0 to 2, necessary to make the electric charge of the whole molecule 0; p and q each represents an integer of 0 to 3, wherein the sum of p and q is 1 or more, and 6 or less.)
摘要翻译：本发明提供一种用于预防或治疗对寄生原虫感染具有高选择性毒性的寄生原虫感染的药物组合物，以及优异的预防或治疗效果。用于预防或治疗寄生原生动物感染的药物组合物包含由以下通式（1）表示的化合物作为活性成分（其中R表示烷基，芳基或杂环基; A和B各自独立地表示5-或含有至少一个杂原子的6元环或其中1个以上3〜8元环稠合的缩合环; Y表示S，O，Se或-NR1-（R1表示烷基，芳基基团或杂环基）; L1，L2，L3，L4和L5各自独立地表示次甲基; Q表示生理上可接受的阴离子; k表示使整个分子0的电荷所必需的0至2的整数; p和q各自表示0〜3的整数，p和q的和为1以上6以下）

32. 发明申请

US20050148831A1 Method of providing healthcare support service, communication unit, and system and apparatus for providing healthcare support 有权
标题翻译：提供医疗支持服务的方法，通信单元以及用于提供医疗支持的系统和装置
公开(公告)号：US20050148831A1
公开(公告)日：2005-07-07
申请号：US11022784
申请日：2004-12-28
申请人： Mariko Shibata , Yoichi Takada , Motoji Haragashira , Kozo Sato
发明人： Mariko Shibata , Yoichi Takada , Motoji Haragashira , Kozo Sato
IPC分类号： A61B5/00 , G06Q50/22 , G08B25/04 , G08B25/10 , H04M11/00 , A61B10/00 , G06F17/60 , G06F17/00
CPC分类号： G06F19/3425 , A61B5/0002 , A61B5/0022 , A61B5/7282 , A61B2505/01 , A61B2505/07 , G06F19/00 , G06F19/34 , G06F19/3418 , G06Q10/00 , G06Q50/22 , G08B1/08 , G16H50/20 , G16H80/00 , Y10S128/92
摘要： A patient terminal can communicate with doctor terminals and a center terminal via a communication network. The patient terminal acquires vital data from a measuring device with a receiving unit. A control unit determines whether the vital data contains an abnormal value and the necessity of messaging depending on the presence or absence of a manual messaging request with a message button and selects the doctor terminal or the center terminal. When it is determined that messaging is necessary, the control unit makes a communication unit call the selected terminal.
摘要翻译：患者终端可以通过通信网络与医生终端和中心终端进行通信。患者终端从具有接收单元的测量装置获取重要数据。控制单元根据存在或不存在具有消息按钮的手动消息传递请求来确定重要数据是否包含异常值以及消息的必要性，并且选择医生终端或中心终端。当确定需要消息传送时，控制单元使通信单元呼叫所选择的终端。

33. 发明授权

US5871895A Silver halide color photographic material 失效
标题翻译：卤化银彩色照相材料
公开(公告)号：US5871895A
公开(公告)日：1999-02-16
申请号：US822686
申请日：1997-03-24
申请人： Kozo Sato
发明人： Kozo Sato
IPC分类号： G03C7/00 , G03C7/38 , G03C1/08 , G03C7/26 , G03C7/32
CPC分类号： G03C7/3835
摘要： A silver halide color photographic material is disclosed which contains at least one 1H-pyrrolo�1,2-c!�1,2,3!triazole based dye-forming coupler represented by the following formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 each represents a hydrogen atom or a substituent; and X represents a hydrogen atom or a group capable of being released upon reaction with the oxidation product of a color developing agent.
摘要翻译：公开了一种卤化银彩色照相材料，其含有至少一种由下式表示的1H-吡咯并[1,2-c] [1,2,3]三唑基染料形成成色剂：其中R1，R2和 R3各自表示氢原子或取代基; X表示氢原子或能够与彩色显影剂的氧化物反应而释放的基团。

34. 发明授权

US5508421A Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye 失效
标题翻译：吡咯三唑偶氮甲碱染料和含有吡咯并三唑甲脒染料的热转印染料
公开(公告)号：US5508421A
公开(公告)日：1996-04-16
申请号：US279191
申请日：1994-07-22
申请人： Makoto Suzuki , Hisashi Mikoshiba , Seiiti Kubodera , Osamu Takahashi , Yasuhiro Shimada , Koushin Matsuoka , Shigeru Yamazaki , Katsuyoshi Yamakawa , Kozo Sato
发明人： Makoto Suzuki , Hisashi Mikoshiba , Seiiti Kubodera , Osamu Takahashi , Yasuhiro Shimada , Koushin Matsuoka , Shigeru Yamazaki , Katsuyoshi Yamakawa , Kozo Sato
IPC分类号： C07D487/04 , C09B55/00 , G03C7/38 , G03C7/36
CPC分类号： C07D487/04 , C09B55/009 , G03C7/383
摘要： A pyrrolotriazole azomethine dye represented by formula (I), (II) or (IV) is disclosed: ##STR1## Also, a heat transfer dye providing material is disclosed, in which the material includes a support having thereon a dye providing layer containing a heat migrating dye, with the dye providing layer containing at least one pyrrolotriazole azomethine dye represented by any of the above formulae (I), (II) and (IV).
摘要翻译：（I），（II）或（IV）表示的吡咯并三氮唑代甲基染料被公开：公开了一种传热染料提供材料，其中所述材料包括其上具有含有热迁移染料的染料提供层的载体，所述染料提供层含有至少一种由上述式（I），（II）和（IV）中的任何一种表示的吡咯并三唑甲脒染料。

35. 发明授权

US5401624A Dye forming couplers and silver halide color photosensitive material containing the same 失效
标题翻译：染料形成成色剂和含有卤化银色光敏材料
公开(公告)号：US5401624A
公开(公告)日：1995-03-28
申请号：US145630
申请日：1993-11-04
申请人： Kozo Sato , Yoshio Ishii , Katsuyoshi Yamakawa
发明人： Kozo Sato , Yoshio Ishii , Katsuyoshi Yamakawa
IPC分类号： C07D487/04 , G03C7/38
CPC分类号： C07D487/04 , G03C7/3825 , G03C7/383
摘要： A silver halide color photosensitive material which forms a cyan dye that has superior heat resistance and that will not readily fade in a reducing atmosphere. The silver halide color photosensitive material contains in at least one layer on a support at least one coupler represented by formula (I): ##STR1## wherein R.sup.1 represents hydrogen atom or a substituent; R.sup.2 represents a substituent; X represents hydrogen atom or a group releasable on a coupling reaction with an oxidation product of a color developing agent; Z.sup.1 represents a nonmetallic atom group necessary for forming a nitrogen-containing, six-membered, heterocyclic ring which has at least one dissociative group: Z.sup.1 cannot be --C(.dbd.O)--N(R)--C(.dbd.O)--NH--; and R represents a substituent.Also disclosed is a novel dye forming coupler which exhibits a high coupling activity and which gives a dye having a large molar extinction coefficient and superior stability, the coupler being represented by the following formula (XX) or (XXI). Also disclosed is a silver halide color photosensitive material which contains at least one of the dye forming couplers of formulae (XX) and (XXI) and which provides sharp dye images with high fastness properties. ##STR2## wherein EWG represents an electron withdrawing group having a Hammett's .sigma..sub.p value of not less than 0.3; R.sub.1 and R.sub.2 each represent a substituent; and X represents hydrogen atom or a group releasable on a coupling reaction with an oxidation product of an aromatic primary amine developing agent.
摘要翻译：一种卤化银色感光材料，其形成具有优异耐热性且不易在还原气氛中褪色的青色染料。卤化银色感光材料在载体上至少一层中含有至少一个由式（I）表示的成色剂：汤姆或取代基; R2表示取代基; X表示氢原子或可与显色剂的氧化产物偶联反应脱离的基团; Z1表示形成具有至少一个解离基团的含氮六元杂环所必需的非金属原子团：Z1不能为-C（= O）-N（R）-C（= O）-NH - ; R表示取代基。还公开了一种新型的染料形成成色剂，其显示出高的偶联活性，并且得到具有大的摩尔吸光系数和优异的稳定性的染料，所述成色剂由下式（XX）或（XXI）表示。还公开了含有式（XX）和（XXI）的染料形成成色剂中的至少一种的卤化银色感光材料，并提供具有高坚牢度性质的清晰的染料图像。（XXI）（XXI）其中EWG表示哈米特σp值不小于0.3的吸电子基团; R1和R2各自表示取代基; X表示氢原子或可与芳族伯胺显影剂的氧化产物偶联反应脱离的基团。

36. 发明授权

US5270153A Cyan image forming method and silver halide color photographic material containing cyan coupler 失效
公开(公告)号：US5270153A
公开(公告)日：1993-12-14
申请号：US797977
申请日：1991-11-26
申请人： Makoto Suzuki , Tadahisa Sato , Kozo Sato , Yoshio Ishii
发明人： Makoto Suzuki , Tadahisa Sato , Kozo Sato , Yoshio Ishii
IPC分类号： G03C7/305 , G03C7/38 , G03C7/407
CPC分类号： G03C7/30529 , G03C7/383
摘要： A silver halide color photographic material comprising a support having thereon at least one light-sensitive silver halide emulsion layer containing at least one 1H-pyrrolo[2,1-c][1,2,4]triazole cyan coupler represented by the following general formula (I) or (II): ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 each represents a hydrogen atom or a substituent, provided that at least one of R.sub.1 and R.sub.2 is an electron withdrawing group which has a Hammett's substituent constant .sigma.p value of 0.15 or more; R.sub.1 and R.sub.2 may be bonded to form a ring; and X represents a hydrogen atom or a substituent capable of being released upon coupling with an oxidation product of an aromatic primary amine color developing agent; said coupler may form a bis-compound or or a polymer at R.sub.1, R.sub.2, R.sub.3 or X; and a cyan image forming method comprising imagewise exposing a silver halide color photographic material comprising a support having thereon at least one light-sensitive silver halide emulsion layer and subjecting the exposed photographic material to color development with an aromatic primary amine color dveloping agent at the presence of the above-described 1H-pyrrolo[2,1c][1,2,4]triazole cyan coupler.

37. 发明授权

US5180652A Light- and heat-sensitive composition, and recording material 失效
标题翻译：光和热敏组合物和记录材料
公开(公告)号：US5180652A
公开(公告)日：1993-01-19
申请号：US466906
申请日：1990-01-18
申请人： Jun Yamaguchi , Sadao Ishige , Kozo Sato , Shintaro Washizu , Isamu Itoh
发明人： Jun Yamaguchi , Sadao Ishige , Kozo Sato , Shintaro Washizu , Isamu Itoh
IPC分类号： G03F7/004 , B41M5/28 , C07C251/68 , G03F7/031 , G03F7/105
CPC分类号： G03F7/031 , B41M5/286 , C07C251/68 , G03F7/105 , Y10S430/116 , Y10S430/165
摘要： A light- and heat-sensitive composition which contains a photo-hardenable composition and at least one dye, a light- and heat-sensitive recording material which contains a support having the composition provided on at least one side thereof, and an image-forming process using the recording material are disclosed.
摘要翻译：一种光和热敏组合物，其含有光硬化组合物和至少一种染料，光敏和热敏记录材料，其含有在其至少一侧上提供的组合物的载体和成像公开了使用记录材料的方法。

38. 发明授权

US5162196A Color coupler for photography and silver halide photographic material comprising the same 失效
标题翻译：用于摄影和银色摄影材料的彩色耦合器
公开(公告)号：US5162196A
公开(公告)日：1992-11-10
申请号：US615797
申请日：1990-11-20
申请人： Kozo Sato , Yasuhiro Shimada , Hideaki Naruse
发明人： Kozo Sato , Yasuhiro Shimada , Hideaki Naruse
IPC分类号： C07C255/23 , C07C255/30 , C07C255/34 , C07C255/35 , C07C255/41 , C07C255/44 , C07C255/45 , G03C7/36
CPC分类号： C07C255/45 , C07C255/23 , C07C255/30 , C07C255/34 , C07C255/35 , C07C255/41 , C07C255/44 , G03C7/36
摘要： The present invention relates to a novel color coupler for photography and a silver halide color photographic material comprising the same, wherein the color coupler is one of the .beta.,.gamma.-unsaturated nitriles represented by formula (I). The invention provides for a color coupler, particularly a cyan coupler, which forms color images less in subsidiary absorption, good in color reproduction, and excellent in fastness, and a silver halide color photographic material having color images as described above. Further the color coupler can be synthesized from inexpensive raw material at a low cost ##STR1## wherein W represents a hydrogen atom or a group capable of being released when the compound is subjected to a coupling reaction with the oxidized product of an aromatic primary amine derivative, R.sub.1 represents a represents a nitrogen atom, R.sub.2 represents a substituent, if V represents ##STR2## R.sub.2 and R.sub.3 each represent substituent, provided that at least one of R.sub.2 and R.sub.3 represents an electron attractive substituent, and provided that if R.sub.2 or R.sub.3 represents an aliphatic group or an aromatic group, the other does not represent an acyl group, and R.sub.1 and R.sub.2 may bond together to form a ring.

39. 发明授权

US5064752A Silver halide photographic materials 失效
标题翻译：卤化银照相材料
公开(公告)号：US5064752A
公开(公告)日：1991-11-12
申请号：US542685
申请日：1990-06-25
申请人： Kazunobu Katoh , Kozo Sato , Keisuke Shiba
发明人： Kazunobu Katoh , Kozo Sato , Keisuke Shiba
IPC分类号： G03C7/26 , G03C1/815 , G03C7/305 , G03C7/388
CPC分类号： G03C7/388
摘要： A silver halide photographic material comprising a support having provided thereon at least two hydrophilic colloid layers, wherein at least one of the hydrophilic layers comprises water or a hydrophilic colloid and a compound represented by formula (I) dispersed therein using water or a water-soluble organic solvent:PWR-(Time).sub.t -PUG (I)wherein PWR represents a group capable of releasing (Time).sub.t -PUG upon reduction;Time represents a group capable of releasing the PUG residual group by the successive reaction, after being released as (Time).sub.t -PUG;t represents 0 or 1;PUG represents a photographically useful group; and at least one water-soluble group exists in one molecule of the compound.
摘要翻译：一种卤化银照相材料，包括其上提供有至少两个亲水胶体层的载体，其中至少一个亲水层包含水或亲水胶体和由式（I）表示的化合物，其中使用水或水溶性分散有机溶剂：PWR-（时间）t-PUG（I）其中PWR表示还原时能够释放（时间）t-PUG的基团; 时间表示在作为（时间）t-PUG释放后能够通过连续反应释放PUG残基的基团; t表示0或1; PUG代表一个摄影有用的组; 并且在该化合物的一个分子中存在至少一个水溶性基团。

40. 发明授权

US4956456A Betaine-type cyan monoazo dyes for dying and printing fibrous materials 失效
公开(公告)号：US4956456A
公开(公告)日：1990-09-11
申请号：US442500
申请日：1989-12-01
申请人： Masaaki Tsukase , Kozo Sato
发明人： Masaaki Tsukase , Kozo Sato
IPC分类号： C09B29/00 , C09B44/00 , C09B44/02
CPC分类号： C09B44/02 , C09B44/00
摘要： The present invention is directed towards a betaine-type monoazo dye for dying and printing fibrous materials, represented by formula (I):Dye--X--Y (I)wherein Dye represents a cyan dye anion represented by formula (II);X represents a bond or linking group;Y represents quaternary ammonium; andDye and X are bonded to each other via A, B.sup.1, B.sup.2, B.sup.3, B.sup.4 or B.sup.5 in formula (II): ##STR1## wherein B.sup.1, B.sup.2, B.sup.3, B.sup.4 and B.sup.5 are the same or different, and each represents a member selected from the group consisting of a bond, hydrogen, alkyl, halogen, --OR.sup.4, --CO.sub.2 R.sup.4, ##STR2## wherein R.sup.4 and R.sup.5 are the same or different and each represents a member selected from the group consisting of hydrogen, alkyl and aryl, or R.sup.4 and R.sup.5 are taken together to form 5- or 6-membered heterocyclic ring containing oxygen, nitrogen, sulfur or combinations thereof as heteroatoms;A represents a member selected from the group consisting of hydrogen, alkyl, aryl, cycloalkyl, a 5- or 6-membered heterocyclic ring containing oxygen, nitrogen, sulfur or combinations thereof as heteroatoms and ##STR3## wherein A.sup.2 and A.sup.3 have the same meaning as A, or A.sup.2 and A.sup.3 are bonded to each other to form a 5- or 6-membered heterocyclic ring containing oxygen, nitrogen, sulfur or combinations thereof as heteroatoms;E represents a member selected from the group consisting of hydrogen, halogen, cyano, hydroxyl, carboxyl, alkyl, aryl, a 5- or 6-membered heterocyclic ring containing oxygen, nitrogen, sulfur or combinations thereof as heteroatoms, alkoxy, aryloxy, alkylthio, arylthio, carbacylamino, sulfonylamino, carbamoyl, amino, alkylsulfonyl and phenylsulfonyl;G represents a member selected from the group consisting of cyano, alkylsulfonyl and phenylsulfonyl;J represents a member selected from the group consisting of hydrogen, halogen, cyano, alkylsulfonyl and phenylsulfonyl; andR.sup.1 represents a member selected from the group consisting of hydrogen and alkyl.

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