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31. 发明申请

US20080167513A1 Strontium-Containing Compounds for Use in the Prevention or Treatment of Necrotic Bone Conditions 审中-公开
标题翻译：用于预防或治疗坏死性骨骼病症的含锶化合物
公开(公告)号：US20080167513A1
公开(公告)日：2008-07-10
申请号：US10590892
申请日：2005-02-28
申请人： Christian Hansen , Henrik Nilsson , Stephan Christgau , Henry G. Bone
发明人： Christian Hansen , Henrik Nilsson , Stephan Christgau , Henry G. Bone
IPC分类号： A61K33/24 , A61M36/00
CPC分类号： A61K33/24 , A61K31/28 , A61K31/56 , A61K31/57 , A61K31/663 , A61K45/06 , A61K2300/00
摘要： A method for the treatment and/or prophylaxis of an ostenonecrotic bone disease in a mammal in need thereof, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis, Legg-Calve-Perthes disease and femoral head necrosis, the method comprising administering an effective dose of a strontium-containing compound (a) to the mammal. A method for the treatment and/or prophylaxis of an osteonecrotic bone disease, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis and femoral head necrosis, in a mammal who is to be or is treated with a therapeutic agent (b) known to or suspected of inducing apoptosis and/or necrosis of bone cells, the method comprising administering a strontium-containing compound (a) in combination with (b).
摘要翻译：用于治疗和/或预防有需要的哺乳动物中的恶性坏死性骨病的方法，例如特发性或继发性骨坏死，无血管性骨坏死，糖皮质激素诱导的骨缺血/骨坏死，Legg-Calve-Perthes疾病和股骨头坏死，所述方法包括向哺乳动物施用有效剂量的含锶化合物（a）。用于治疗和/或预防将要或被治疗的哺乳动物中的骨坏死性骨病，例如特发性或继发性骨坏死，无血管性骨坏死，糖皮质激素诱导的骨缺血/骨坏死和股骨头坏死的方法具有已知或怀疑诱导骨细胞凋亡和/或坏死的治疗剂（b），该方法包括与（b）组合施用含锶化合物（a）。

32. 发明申请

US20060216358A1 Controlled release composition containing a strontium salt 审中-公开
标题翻译：含有锶盐的控释组合物
公开(公告)号：US20060216358A1
公开(公告)日：2006-09-28
申请号：US10556150
申请日：2004-05-06
申请人： Christian Hansen , Henrik Nilsson , Jens Andersen , Stephan Christgau
发明人： Christian Hansen , Henrik Nilsson , Jens Andersen , Stephan Christgau
IPC分类号： A61K33/24 , A61K33/42 , A61K31/7008 , A61K31/375 , A61K31/192 , A61K31/19 , A61K31/185
CPC分类号： A61K33/00 , A61K31/28 , A61K31/592 , A61K31/593 , A61K33/24 , A61K45/06 , A61K2300/00
摘要： A controlled release pharmaceutical composition comprising a strontium salt. The invention also relates to the use of a strontium salt for treating a male suffering from diseases and conditions affecting metabolism and/or structural integrity of cartilage and/or bone. The invention also relates to the use of a strontium-containing compound for preventing a cartilage and/or bone condition in a subject, and for the treatment and/or prophylaxis of secondary osteoporosis.
摘要翻译：包含锶盐的控释药物组合物。本发明还涉及锶盐用于治疗患有软骨和/或骨的代谢和/或结构完整性的疾病和病症的男性。本发明还涉及含锶化合物用于预防受试者的软骨和/或骨骼状况以及用于治疗和/或预防继发性骨质疏松症的用途。

33. 发明授权

US5999422A Control equipment for an active filter 有权
标题翻译：有源滤波器的控制设备
公开(公告)号：US5999422A
公开(公告)日：1999-12-07
申请号：US155890
申请日：1998-12-28
申请人： Tor Goransson , Henrik Nilsson , Anders berg
发明人： Tor Goransson , Henrik Nilsson , Anders berg
IPC分类号： H02J1/02 , H02J3/01 , H02J3/36 , H02M1/15 , H02M7/06 , H02M1/14 , H02H7/00
CPC分类号： H02J3/36 , Y02E60/60
摘要： An active filter (2) is connected to a dc circuit (L1, L2) in a converter (SR1) in an installation for transmission of high-voltage direct current. Control equipment (5) generates, in dependence on a control signal, a control order (SCF) for the active filter which, in dependence thereon, generates and supplies to the dc connection one of a filter voltage (UF) and a filter current (IF) for reducing at least one tone of a chosen tone frequency in a current (Id) in the dc connection. The control equipment comprises a controlling unit which forms a controller signal in dependence on a supplied current measurement value (IM) of the current in the dc connection, and an identification unit. The identification unit forms a first compensating parameter in dependence on the current measurement value and on an excitation signal generated by the control equipment and added to the control order. The control equipment forms the control signal in dependence on the controlling signal and the compensating parameter, which has been formed such that the sum thereof and of the phase shift for a transfer function from the control signal to the current measurement value at the chosen tone frequency is at least approximately equal to a preselected value.
摘要翻译： PCT No.PCT / SE98 / 00421 Sec。 371日期1998年12月28日第 102（e）1998年12月28日PCT PCT 1998年3月10日PCT公布。第WO98 / 21924号公报日期1998年5月28日在高压直流传输装置中，有源滤波器（2）连接到转换器（SR1）中的直流电路（L1，L2）。控制设备（5）根据控制信号产生用于有源滤波器的控制顺序（SCF），所述有源滤波器根据其生成并向滤波器电压（UF）和滤波器电流（UF） IF），用于在直流连接中的当前（Id）中减少所选音调频率的至少一个音调。控制装置包括控制单元，该控制单元根据直流连接中的电流的供给电流测量值（IM）和识别单元形成控制器信号。识别单元根据当前测量值和由控制设备产生的激励信号，并根据控制顺序形成第一补偿参数。控制装置根据控制信号和补偿参数形成控制信号，所述控制信号和补偿参数被形成为使得其与所选音调频率之间的从控制信号到当前测量值的传递函数的相移和相移至少近似等于预选值。

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