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31. 发明授权

US5578469A Process for preparing neotrehalose, and its uses 失效
标题翻译：制备新海藻糖及其用途的方法
公开(公告)号：US5578469A
公开(公告)日：1996-11-26
申请号：US22340
申请日：1993-02-24
申请人： Takashi Shibuya , Hiroto Chaen , Shuzo Sakai , Toshio Miyake
发明人： Takashi Shibuya , Hiroto Chaen , Shuzo Sakai , Toshio Miyake
IPC分类号： A23C9/13 , A23C9/152 , A23G1/00 , A23G1/30 , A23G3/00 , A23G3/34 , A23G4/00 , A23L2/39 , A23L9/20 , A23L15/00 , A23L21/10 , A23L27/30 , A23L33/20 , A61K9/28 , A61K31/70 , A61P3/00 , A61P7/00 , A61P17/00 , C12P19/12 , C12P19/14 , C12P1/04 , A61K38/43 , A61K38/46
CPC分类号： C12P19/14 , C12P19/12 , Y10S435/839
摘要： Disclosed are a novel preparation of neotrehalose and its uses. The preparation comprises allowing .alpha.-amylase to act on an amylaceous substance to form neotrehalose, and recovering said neotrehalose. The neotrehalose has a satisfiable chemical stability, as well as other properties such as a sweeteness, energy-imparting ability, osmosis-regulating ability, filler-imparting ability, gloss-imparting ability, moisture-retaining ability, viscosity-imparting ability, crystallization-preventing ability, and non-fermentability. These properties render the neotrehalose advantageously useful in preparations of a variety of compositions.
摘要翻译：公开了新海藻糖及其用途的新型制备方法。该制剂包括使α-淀粉酶作用于淀粉物质以形成新海藻糖，并回收所述新海藻糖。新海藻糖具有令人满意的化学稳定性，以及其它性能，如甜度，能量赋予能力，渗透调节能力，赋予赋形能力，赋予光泽的能力，保湿能力，粘度赋予能力，预防能力和不发酵能力。这些性质使得新海藻糖有利地用于各种组合物的制备。

32. 发明授权

US5296473A Process for preparing a powder having a high concentration of lactosucrose and use of said powder 失效
标题翻译：制备具有高浓度乳糖蔗糖的粉末和使用所述粉末的方法
公开(公告)号：US5296473A
公开(公告)日：1994-03-22
申请号：US850609
申请日：1992-03-13
申请人： Kozo Hara , Kohki Fujita , Masayuki Yamashita , Yasuhiko Tsunetomi , Shuzo Sakai , Toshio Miyake
发明人： Kozo Hara , Kohki Fujita , Masayuki Yamashita , Yasuhiko Tsunetomi , Shuzo Sakai , Toshio Miyake
IPC分类号： A23C9/156 , A23F5/24 , A23G1/00 , A23G1/56 , A23G3/34 , A23G4/00 , A23G4/10 , A23K1/16 , A23L1/187 , A23L1/236 , C12P19/18 , C13K13/00 , A61K31/70 , A61K31/715 , C12P19/04
CPC分类号： A23G4/10 , A23C9/156 , A23F5/243 , A23G1/56 , A23G3/346 , A23K20/163 , A23L27/33 , A23L9/10 , C12P19/18 , C12Y204/0101 , C12Y302/01026 , C13K13/00 , A23G2200/06 , Y10S435/803 , Y10S435/83
摘要： The lactosucrose high-content powder according to the present invention is prepared by allowing an aqueous solution containing sucrose and lactose to act on a saccharidetransferring enzyme, removing concomitant saccharides in the resultant saccharide solution containing lactosucrose to obtain a solution having a high concentration of lactosucrose, i.e. lactosucrose content of 45 w/w % or more of the sugar composition, and spraydrying the resultant solution to obtain a powder having a high concentration of lactosucrose. The powder is incorporated in an orally- or parenterally-administrable product to obtain an orally- or parenterally-administrable product which exerts a selective growth-promoting-effect on a microorganism of the genus Bifidobacterium in vivo.
摘要翻译：根据本发明的乳糖蔗糖高含量粉末是通过使含有蔗糖和乳糖的水溶液作用于糖转移酶，除去所得到的含有蔗糖的糖溶液中的伴随糖，得到具有高浓度的乳糖蔗糖的溶液，即乳糖蔗糖含量为糖组成的45w / w％以上，喷雾干燥所得溶液，得到乳糖浓度高的粉末。将粉末掺入口服或肠胃外给药的产品中以获得在体内对双歧杆菌属的微生物施加选择性生长促进作用的口服或肠胃外给药的产品。

33. 发明授权

US5218096A Lactoneotrehalose, and its preparation and uses 失效
标题翻译： LactoneOTREHALOSE，及其制备和用途
公开(公告)号：US5218096A
公开(公告)日：1993-06-08
申请号：US772716
申请日：1991-10-07
申请人： Takashi Shibuya , Hiroto Chaen , Shuzo Sakai
发明人： Takashi Shibuya , Hiroto Chaen , Shuzo Sakai
IPC分类号： A23L27/30 , A23G3/34 , A23G4/00 , A23G4/10 , A61K8/60 , A61K9/00 , A61K9/20 , A61K38/19 , A61K38/21 , A61K47/26 , A61Q7/00 , A61Q11/00 , A61Q19/00 , C07H3/06 , C08B33/04 , C12P19/14 , C12P19/16 , C12P19/18 , C12P19/20
CPC分类号： C12P19/18 , A23G3/346 , A23G4/10 , A61K38/191 , A61K38/21 , A61K47/26 , A61K8/60 , A61K9/0014 , A61K9/0019 , A61K9/2018 , A61Q19/00 , C07H3/06 , C12P19/14 , A23G2200/06 , A61Q11/00 , A61Q17/04 , A61Q19/02 , A61Q5/00 , A61Q7/00
摘要： Lactoneotrehalose, a novel saccharide shown by the formula O-.beta.-D-galactopyranosyl-(1.fwdarw.4)-O-.beta.-D-glucopyranosyl .alpha.-D-glucopyranoside, is prepared by allowing a saccharide-transferring enzyme to act on an aqueous solution containing lactose and amylaceous substance. Lactoneotrehalose is a non-reducing oligosaccharide, extremely stable, readily soluble in water, and substantially free of hygroscopicity, as well as having a satisfiable quality and moderate sweetness. These render lactoneotrehalose very useful in the preparations of orally-administrable products, cosmetics and pharmaceuticals.

34. 发明授权

US5130239A Process for preparing lactosucrose high-content power 失效
标题翻译：制备乳酸菌高含量功能的方法
公开(公告)号：US5130239A
公开(公告)日：1992-07-14
申请号：US665828
申请日：1991-03-07
申请人： Kozo Hara , Kohki Fujita , Masayuki Yamashita , Yasuhiko Tsunetomi , Shuzo Sakai , Toshio Miyake
发明人： Kozo Hara , Kohki Fujita , Masayuki Yamashita , Yasuhiko Tsunetomi , Shuzo Sakai , Toshio Miyake
IPC分类号： A23C9/156 , A23F5/24 , A23G1/00 , A23G1/56 , A23G3/34 , A23G4/00 , A23G4/10 , A23K1/16 , A23L1/187 , A23L1/236 , C12P19/18 , C13K13/00
CPC分类号： A23G4/10 , A23C9/156 , A23F5/243 , A23G1/56 , A23G3/346 , A23K20/163 , A23L27/33 , A23L9/10 , C12P19/18 , C12Y204/0101 , C12Y302/01026 , C13K13/00 , A23G2200/06 , Y10S435/803 , Y10S435/83
摘要： The lactosucrose high-content powder according to the present invention is prepared by allowing an aqueous solution containing sucrose and lactose to act on a saccharide-transferring enzyme, removing concomitant saccharides in the resultant saccharide solution containing lactosucrose to obtain a lactosucrose high-content solution with a lactosucrose content of 45 w/w % or higher on sugar composition, and spray-drying the resultant solution to obtain a lactosucrose high-content powder. The powder is incorporated in an orally- or parenterally-administrable product to obtain an orally- or parenterally-administrable product which exerts a selective growth-promoting-effect on a microorganism of the genus Bifidobacterium in vivo.

35. 发明授权

US4849225A Process to prepare solid products containing oil-soluble substance 失效
标题翻译：制备含有油溶性物质的固体产品的方法
公开(公告)号：US4849225A
公开(公告)日：1989-07-18
申请号：US70138
申请日：1987-06-29
申请人： Masakazu Mitsuhashi , Shuzo Sakai , Toshio Miyake
发明人： Masakazu Mitsuhashi , Shuzo Sakai , Toshio Miyake
IPC分类号： A61K8/60 , A21D2/00 , A21D2/08 , A21D10/00 , A23D9/00 , A23D9/02 , A23G3/34 , A23J7/00 , A23L1/03 , A23L1/09 , A23L1/22 , A61K8/00 , A61K8/11 , A61K8/73 , A61K31/20 , A61K47/00 , A61K47/26 , A61Q13/00 , A61Q90/00 , C11B9/00 , C11B15/00 , C13K7/00
CPC分类号： A61K47/26 , A23G3/346 , A23L27/70 , A23L29/30 , A61K31/20 , A23G2200/06
摘要： Disclosed is a novel process to prepare a solid product containing an oil-soluble substance (e.g. oil and fat, spice, flavor, vitamin, emulsifier, hormone, higher fatty acid, unsaponifiable substance and complex lipid), comprising adding to an oil-soluble liquid substance an anhydrous maltose (e.g. anhydrous crystalline alpha-maltose, anhydrous crystalline beta-maltose and anhydrous amorphous maltose) along with water, and crystallizing beta-maltose hydrate in the mixture.
摘要翻译：公开了一种制备含有油溶性物质（例如油脂，香料，风味剂，维生素，乳化剂，激素，高级脂肪酸，不皂化物质和复合脂质）的固体产品的新方法，包括向油溶性液体物质和无水麦芽糖（例如无水结晶α-麦芽糖，无水结晶β-麦芽糖和无水无定形麦芽糖）以及水中的结晶β-麦芽糖水合物。

36. 发明授权

US4826825A Dehydration of hydrous product using anhydrous lactitol 失效
标题翻译：使用无水乳糖醇脱水含水产物
公开(公告)号：US4826825A
公开(公告)日：1989-05-02
申请号：US942422
申请日：1986-12-16
申请人： Masakazu Mitsuhashi , Shuzo Sakai , Toshio Miyake
发明人： Masakazu Mitsuhashi , Shuzo Sakai , Toshio Miyake
IPC分类号： B01J20/22 , A21D2/18 , A21D10/00 , A23B7/08 , A23C9/123 , A23C13/12 , A23C15/14 , A23G3/34 , A23L1/00 , A23L1/03 , A23L1/09 , A23L1/10 , A23L1/202 , A23L1/238 , A23L1/24 , A23L1/32 , A23L1/326 , A23L3/3463 , A23L3/349 , A23L3/40 , A23L3/42 , A61K8/60 , A61K9/14 , A61K35/00 , A61K38/00 , A61K38/21 , A61K45/06 , A61K47/00 , A61K47/10 , A61K47/26 , A61P3/02 , A61Q5/00 , A61Q19/00 , F26B5/16 , C08L5/00
CPC分类号： A61Q19/00 , A21D2/181 , A23C13/125 , A23C15/14 , A23C9/1232 , A23L15/20 , A23L29/37 , A23L3/3463 , A23L3/42 , A61K8/60 , A61K9/14 , F26B5/16 , A61Q11/00 , A61Q5/00
摘要： A novel dehydration process using anhydrous lactitol as the desiccant is disclosed. Anhydrous lactitol is converted into the crystalline hydrate and acts as the desiccant when incorporated into a hydrous product. The dehydration is applicable to hydrous products, such as foods, pharmaceuticals, cosmetics, and their materials and intermediates.
摘要翻译：公开了一种使用无水乳糖醇作为干燥剂的新型脱水方法。将无水乳糖醇转化为结晶水合物，并且当掺入含水产品中时用作干燥剂。脱水适用于含水产品，如食品，药品，化妆品及其材料和中间体。

37. 发明授权

US4816445A Crystalline alpha-maltose 失效
标题翻译：结晶α-麦芽糖
公开(公告)号：US4816445A
公开(公告)日：1989-03-28
申请号：US739316
申请日：1985-05-30
申请人： Masakazu Mitsuhashi , Shuzo Sakai , Toshio Miyake
发明人： Masakazu Mitsuhashi , Shuzo Sakai , Toshio Miyake
IPC分类号： A23L1/09 , C07H3/04 , C13K7/00 , C12G3/00
CPC分类号： C07H3/04 , A23L29/30 , C13K7/00
摘要： A crystalline alpha-maltose with an alpha-maltose isomer content of 55% or higher is prepared by the process comprising preparing a high-concentration syrup, with a moisture content lower than 10 w/w %, from a high-purity maltose with a maltose content of 85% or higher; crystallizing alpha-maltose from the syrup at a temperature within the range of 50.degree.-130.degree. C. in the presence of seed crystal; and recovering the resultant crystalline alpha-maltose with an alpha-maltose isomer content of 55% or higher. The crystalline alpha-maltose is superior to crystalline beta-maltose hydrate in solubility and dispersibility in aqueous media. The crystalline alpha-maltose is a suitable maltose material for food products and pharmaceuticals. A ready-mix-type parenteral hyperalimentation which is highly resistant to browning and alteration is prepared with the crystalline alpha-maltose.
摘要翻译：具有55％以上α-麦芽糖异构体含量的结晶α-麦芽糖通过包括从高纯度麦芽糖制备含有低于10w / w％的高浓度糖浆的方法制备，麦芽糖含量在85％以上; 在晶种存在下，在50〜130℃的温度范围内，从糖浆中结晶α-麦芽糖; 并以α-麦芽糖异构体含量为55％以上回收所得结晶α-麦芽糖。结晶α-麦芽糖在水性介质中的溶解度和分散性优于结晶β-麦芽糖水合物。结晶α-麦芽糖是食品和药物的合适的麦芽糖材料。用结晶的α-麦芽糖制备高度抗褐变和变性的预混合型肠胃外过度活化。

38. 发明授权

US4758660A Crystalline erlose 失效
标题翻译：结晶黑色
公开(公告)号：US4758660A
公开(公告)日：1988-07-19
申请号：US786823
申请日：1985-10-11
申请人： Kanou Takeuchi , Shuzo Sakai , Toshio Miyake
发明人： Kanou Takeuchi , Shuzo Sakai , Toshio Miyake
IPC分类号： A23L29/10 , A23L27/30 , A61K8/00 , A61K8/60 , A61K8/73 , A61K8/98 , A61K9/20 , A61K47/00 , A61K47/26 , A61Q11/00 , C07H3/06 , C12P19/18 , C07H1/00 , C07G17/00 , C07H1/06 , C07H3/00
CPC分类号： C07H3/06 , C12P19/18
摘要： Disclosed are hitherto-unknown erlose hydrate, a mixture solid containing the same, and their production and uses. One mole of the erlose hydrate has 1 or 3 moles of cystallization water. The erlose hydrate and a mixture solid containing the same are readily dissolvable in water, non- or scarcely-hygroscopic, low-cariogenic, low-calorific, and, therefore, favorably usable to prepare orally-usable products, e.g. foodstuffs in general, cosmetics, dentifrices, pharmaceuticals, and chemicals.
摘要翻译：公开了迄今为止未知的黑体水合物，含有它们的混合物及其生产和用途。 1摩尔的含水合物含1或3摩尔的结晶水。所述含水合物和含有该水合物的混合物易于溶于水，非吸湿性或几乎不吸湿性，低致龋性，低热量，因此可有利地用于制备口服可用的产品。一般食品，化妆品，洁齿剂，药品和化学品。

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