专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明公开

EP1755568A4 CONTROLLED RELEASE FORMULATION FOR ORAL ADMINISTRATION OF METFORMIN 有权
标题翻译：控释制剂口服二甲双胍
公开(公告)号：EP1755568A4
公开(公告)日：2010-03-03
申请号：EP05733390
申请日：2005-03-31
申请人： HANMI PHARM IND CO LTD
发明人： WOO JONG SOO , KIM YOUNG HUN
IPC分类号： A61K9/52 , A61K47/30 , A61K9/20 , A61K31/155 , A61K47/10 , A61K47/32 , A61K47/36
CPC分类号： A61K9/205 , A61K9/2027 , A61K9/2031 , A61K9/2077

32. 发明公开

EP1558214A4 MICROEMULSION CONCENTRATE FOR ORAL ADMINISTRATION OF WATER-INSOLUBLE ANTI-COLD DRUG AND METHOD FOR PREPARING SAME 有权
标题翻译：微乳液浓缩液，对预防感冒口服水的药物及其制造方法
公开(公告)号：EP1558214A4
公开(公告)日：2009-12-09
申请号：EP03810716
申请日：2003-11-07
申请人： HANMI PHARM IND CO LTD
发明人： WOO JONG SOO , KIM AE GUK
IPC分类号： A61K9/107 , A61K31/137 , A61K31/192 , A61K47/10 , A61K47/26
CPC分类号： A61K9/1075 , A61K31/137 , A61K31/192 , A61K47/10 , A61K47/26

33. 发明公开

EP1663231A4 ORAL ITRACONAZOLE COMPOSITION WHICH IS NOT AFFECTED BY INGESTED FOOD AND PROCESS FOR PREPARING SAME 审中-公开
标题翻译：伊曲康唑口服组合未营养受到影响，及其制造方法
公开(公告)号：EP1663231A4
公开(公告)日：2009-04-29
申请号：EP04774524
申请日：2004-09-07
申请人： HANMI PHARM IND CO LTD
发明人： WOO JONG SOO , YI HONG GI
IPC分类号： A61K31/496
CPC分类号： A61K9/4858 , A61K31/496
摘要： An oral itraconazole composition which is not affected by ingested food and a preparation method thereof are provided, which itraconazole composition forms stable emulsified microparticles when it is orally administered to enhance bioavailability of itraconazole, and is not affected by pH and ingested food, so that the difference of absorption in individuals can be reduced. The oral high viscosity glassy composition which is not affected by ingested food comprises itraconazole, acidifying agent, amphiphilic additives, volatile additives, surfactant and oil, wherein the bioavailability ratio of itraconazole before to after digestion is 0.8 or more; the viscosity of the composition is 10,000cps at 25 deg. C; the composition has self-microemulsifying capability; the acidifying agent is selected from phosphoric acid, hydrochloric acid and a solution thereof; the amphiphilic additive is selected from transcutol, dimethyl isosorbide, glycofurol, propylene glycol, propylene carbonate, solutol and a mixture thereof; the surfactant is selected from a reaction product of natural or hydrogenated vegetable oil and ethylene glycol, polyoxyethylene-sorbitan-fatty acid ester, polyoxyethylene fatty acid ester and a mixture thereof; and the oil is tocopherol, its derivatives and a mixture thereof. The method for preparing the oral itraconazole composition which is not affected by ingested food comprises the steps of: (a) dissolving itraconazole in a mixed solution of acidifying agent, amphiphilic additives and volatile additives; (b) adding surfactant and oil into the mixture and dissolving them; and (c) removing the volatile additives from the mixed solution, wherein the volatile additive is C2-C3 alcohol.

34. 发明公开

EP1109532A4 ORAL MICRO-EMULSION COMPOSITION OF SILYBIN 有权
标题翻译：口腔用组合物微乳液的水飞蓟宾
公开(公告)号：EP1109532A4
公开(公告)日：2003-05-07
申请号：EP00941017
申请日：2000-07-05
申请人： HANMI PHARM IND CO LTD
发明人： WOO JONG SOO , SUH HEUN JOO
IPC分类号： A61K36/19 , A61K9/107 , A61K31/357 , A61K36/28 , A61K47/10 , A61K47/12 , A61K47/16 , A61K47/20 , A61K47/22 , A61K47/24 , A61K47/28 , A61K47/34 , A61K47/44 , A61P1/16
CPC分类号： A61K36/28 , A61K9/1075 , Y10S514/893 , Y10S514/937
摘要： An oral micro-emulsion composition comprising a Carduus marianus extract, silybin or a silybin derivative; an organic solvent; a surfactant; and an oil provides a high in vivo bioavailability of silybin.

35. 发明公开

EP3162363A4 COMPOSITE PREPARATION COMPRISING ACTIVE INGREDIENT-CONTAINING FILM COATING LAYER 有权
公开(公告)号：EP3162363A4
公开(公告)日：2018-01-03
申请号：EP15816054
申请日：2015-06-30
申请人： HANMI PHARM IND CO LTD
发明人： KIM HYUNG SEO , CHO JUNG HYUN , CHOI YOUNG KEUN , KIM KYEONG SOO , KIM JIN CHEUL , KIM YONG IL , PARK JAE HYUN , WOO JONG SOO
IPC分类号： A61K9/20 , A61K9/48 , A61K45/06 , A61K47/30 , A61K47/32
CPC分类号： A61K9/4808 , A61K9/209 , A61K31/18 , A61K31/4985 , A61K31/58 , A61K45/06 , A61K2300/00
摘要： Provided are a composite preparation and a method for producing same, the composite preparation comprising a core containing a first active ingredient; and a film coating layer containing a 5-±-reductase inhibitor, wherein the film coating layer is formed by coating with a film coating solution in which the film coating materials are dissolved in a mixed solvent of water and about 30-80 wt% of an organic solvent with respect to a total weight of the mixed solvent.

36. 发明公开

EP3154975A4 TENOFOVIR DISOPROXIL PHOSPHATE, AND PHARMACEUTICAL COMPOSITION THEREOF COMPRISING NON-METALLIC SALT DISINTEGRANT AND NON-METALLIC SALT LUBRICANT 审中-公开
公开(公告)号：EP3154975A4
公开(公告)日：2018-01-03
申请号：EP15814377
申请日：2015-07-01
申请人： HANMI PHARM IND CO LTD
发明人： CHO JUNG HYUN , CHOI YOUNG KEUN , KIM HYUNG SEO , KIM KYEONG SOO , KIM YONG IL , PARK JAE HYUN , WOO JONG SOO
IPC分类号： C07D473/34 , A61K9/20 , A61K31/52 , A61P31/12 , C07F9/02 , C07F9/6561
CPC分类号： C07D473/34 , A61K9/2004 , A61K9/2013 , A61K9/2018 , A61K9/2054 , A61K9/2059 , A61K9/2068 , C07F9/65616
摘要： A tenofovir disoproxil phosphate, and a pharmaceutical composition including tenofovir disoproxil phosphate or a pharmaceutically acceptable salt thereof, a non-metallic salt disintegrant, and a non-metallic salt lubricant are provided.

37. 发明公开

EP3068380A4 COMPOSITE FORMULATION COMPRISING TADALAFIL AND AMLODIPINE 审中-公开
标题翻译： VERBUNDFORMULIERUNG MIT TADALAFIL UND AMLODIPIN
公开(公告)号：EP3068380A4
公开(公告)日：2017-06-28
申请号：EP14861867
申请日：2014-11-06
申请人： HANMI PHARM IND CO LTD
发明人： KIM JIN CHEUL , KIM JAE HO , PARK CALEB HYUNGMIN , KIM YONG IL , PARK JAE HYUN , WOO JONG SOO
IPC分类号： A61K9/20 , A61K9/16 , A61K9/48 , A61K31/44 , A61K31/4985 , A61K47/30 , A61K47/40
CPC分类号： A61K9/2077 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K9/1682 , A61K9/2013 , A61K9/2018 , A61K9/2054 , A61K9/2059 , A61K9/2095 , A61K31/4422 , A61K31/4985 , A61K2300/00

38. 发明公开

EP3073998A4 PHARMACEUTICAL COMBINATION FORMULATION COMPRISING AMLODIPINE, LOSARTAN AND ROSUVASTATIN 审中-公开
标题翻译： PHARMAZEUTISCHE KOMBINATIONSFORMULIERUNG MIT AMLODIPIN，LOSARTAN UND ROSUVASTATIN
公开(公告)号：EP3073998A4
公开(公告)日：2017-05-31
申请号：EP14866739
申请日：2014-11-20
申请人： HANMI PHARM IND CO LTD
发明人： CHO HYUK JUN , IM HO TAEK , JEONG MYOUNG KI , KIM YONG IL , PARK JAE HYUN , WOO JONG SOO
IPC分类号： A61K9/24 , A61K31/4178 , A61K31/4422 , A61K31/505 , A61K47/32 , A61K47/38
CPC分类号： A61K9/209 , A61K9/2018 , A61K9/2054 , A61K9/2095 , A61K31/4178 , A61K31/4422 , A61K31/505
摘要： Disclosed is a pharmaceutical combination formulation comprising a first discrete part containing amlodipine and rosuvastatin and a second discrete part containing losartan, which exhibits improved dissolution rate and stability. The inventive combination formulation comprising amlodipine, losartan and rosuvastatin having different action mechanisms from one another can be effectively used to prevent or treat a cardiovascular disorder. Designed to minimize an interaction among active ingredients, the pharmaceutical combination formulation exhibits excellent storage stability and dissolution rates of amlodipine, losartan and rosuvastatin, and thus can be useful in pharmaceutical industries.
摘要翻译：公开了药物组合制剂，其包含含有氨氯地平和罗苏伐他汀的第一离散部分和含有氯沙坦的第二离散部分，所述第二离散部分表现出改进的溶解速率和稳定性。包含彼此具有不同作用机制的氨氯地平，氯沙坦和罗苏伐他汀的本发明组合制剂可以有效地用于预防或治疗心血管疾病。设计用于最小化活性成分之间的相互作用，药物组合制剂表现出优异的氨氯地平，氯沙坦和瑞舒伐他汀的储存稳定性和溶出速率，因此可用于制药工业。

39. 发明公开

EP3162363A1 COMPOSITE PREPARATION COMPRISING ACTIVE INGREDIENT-CONTAINING FILM COATING LAYER 有权
标题翻译： ZUSAMMENGESETZTE ZUBEREITUNG MIT WIRKSTOFFHALTIGER FILMBESCHICHTUNG
公开(公告)号：EP3162363A1
公开(公告)日：2017-05-03
申请号：EP15816054
申请日：2015-06-30
申请人： HANMI PHARM IND CO LTD
发明人： KIM HYUNG SEO , CHO JUNG HYUN , CHOI YOUNG KEUN , KIM KYEONG SOO , KIM JIN CHEUL , KIM YONG IL , PARK JAE HYUN , WOO JONG SOO
IPC分类号： A61K9/20 , A61K9/48 , A61K47/30 , A61K47/32
CPC分类号： A61K9/4808 , A61K9/209 , A61K31/18 , A61K31/4985 , A61K31/58 , A61K45/06 , A61K2300/00
摘要： Provided are a composite preparation and a method for producing same, the composite preparation comprising a core containing a first active ingredient; and a film coating layer containing a second active ingredient, wherein the film coating layer comprises a polyvinyl alcohol-polyethylene glycol graft copolymer and polyvinyl alcohol.
摘要翻译：本发明提供一种复合制剂及其制造方法，该复合制剂包含含有第一活性成分的核心; 以及含有第二活性成分的薄膜包衣层，其中所述薄膜包衣层包含聚乙烯醇 - 聚乙二醇接枝共聚物和聚乙烯醇。

40. 发明公开

EP2861219A4 DRY POWDER FOR INHALATION FORMULATION COMPRISING SALMETEROL XINAFOATE, FLUTICASONE PROPIONATE AND TIOTROPIUM BROMIDE, AND METHOD FOR PREPARING SAME 审中-公开
标题翻译：干粉吸入制剂沙美特罗，丙酸氟替卡松和噻托溴THEREOF及其制备方法
公开(公告)号：EP2861219A4
公开(公告)日：2015-10-28
申请号：EP13804439
申请日：2013-06-03
申请人： HANMI PHARM IND CO LTD
发明人： KIM KYEONG SOO , LEE DEOKKYU , KIM DONG HO , KIM YONG IL , PARK JAE HYUN , WOO JONG SOO
IPC分类号： A61K9/14 , A61K9/16 , A61K31/136 , A61K31/137 , A61K31/166 , A61K31/439 , A61K31/46 , A61K31/56 , A61K31/568
CPC分类号： A61K31/56 , A61K9/0075 , A61K9/145 , A61K31/136 , A61K31/137 , A61K31/439 , A61K31/46 , A61K31/568 , A61K47/26 , A61K2300/00

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式