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31. 发明申请

US20100056909A1 Methods for Controlling Medical Fluid Injections 有权
标题翻译：控制医用液体注射的方法
公开(公告)号：US20100056909A1
公开(公告)日：2010-03-04
申请号：US12615534
申请日：2009-11-10
申请人： Frank M. Fago , James E. Knipfer
发明人： Frank M. Fago , James E. Knipfer
IPC分类号： A61B6/00
CPC分类号： A61M31/005 , A61B6/481 , A61B6/504 , A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/172 , A61M2005/14208 , A61M2205/3362 , A61M2205/6018 , A61M2205/6054 , A61M2205/70
摘要： The present invention is directed to control of medical fluid injection systems. For instance, in some embodiments, an injection protocol may be initiated, and an actual flow rate of the medical fluid utilized in the injection protocol may be adjusted based, at least in part, on an inherent system elasticity of the injection system.
摘要翻译：本发明涉及药液注射系统的控制。例如，在一些实施例中，可以启动注射方案，并且可以至少部分地基于注射系统的固有系统弹性来调整在注射方案中使用的医用流体的实际流速。

32. 发明授权

US07081104B2 Method and apparatus for injecting fluid into animals and disposable front loadable syringe therefor 失效
标题翻译：用于将动物注射到动物中的方法和装置以及一次性前置可装载的注射器
公开(公告)号：US07081104B2
公开(公告)日：2006-07-25
申请号：US10730302
申请日：2003-12-08
申请人： Charles Neer , Frank M. Fago , Paul E. Dieterlen , James H. Goethel
发明人： Charles Neer , Frank M. Fago , Paul E. Dieterlen , James H. Goethel
IPC分类号： A61M1/00 , A61M5/315
CPC分类号： A61M5/14546 , A61M5/14566 , A61M5/1458 , A61M2250/00 , Y10S128/01
摘要： An animal fluid injector, replaceable syringe and method of replacement of the syringe in the injector are provided in which the syringe is loadable and unloadable into and from the injector through the open front end of a pressure jacket of the injector, thereby permitting replacement without retraction of the syringe plunger drive or disconnection of the injection tubing. The syringe is provided with a pressure restraining front end, such as an integral or removable cap with structure such as threads that lock the syringe to the front end of the jacket by mating with threads on the jacket. A mechanism in the injector, which includes, for example, a key on cam ring operated by a lever with one hand of an operator, interacts with structure such asymmetrically spaced notches on the back end of the syringe to, for example, rotate the syringe and simultaneously translate or rotate a coupling on the syringe plunger into and out of engagement with the plunger drive in the injector.
摘要翻译：提供动物流体注射器，可替换的注射器和注射器中更换注射器的方法，其中注射器可通过注射器的压力套的敞开的前端装载和卸载注射器，从而允许更换而不缩回注射器柱塞驱动或注射管的断开。注射器设置有压力限制前端，例如具有诸如螺纹的结构的整体或可移除的盖，其通过与护套上的螺纹配合将注射器锁定到护套的前端。注射器中的机构，其包括例如由操作者的一只手操作的杠杆操作的凸轮环上的键与注射器后端上的这种不对称间隔的凹口的结构相互作用，例如旋转注射器并且同时将注射器柱塞上的联接器平移或旋转进入注射器中的柱塞驱动器并与其脱离接合。

33. 发明授权

US5913844A Power injector and method providing removal of used disposable syringe 失效
标题翻译：动力注射器和方法提供使用过的一次性注射器的去除
公开(公告)号：US5913844A
公开(公告)日：1999-06-22
申请号：US877083
申请日：1997-06-17
申请人： Robert J. Ziemba , Frank M. Fago , Charles Neer
发明人： Robert J. Ziemba , Frank M. Fago , Charles Neer
IPC分类号： A61M5/00 , A61M5/145 , A61M37/00
CPC分类号： A61M5/14546 , A61M5/007 , A61M5/14566
摘要： A power injector is provided for injecting fluid from a replaceable syringe and through an injection tube into the body of an animal. The syringe includes one or more operator-removable and interchangeable syringe mounting heads, at least one of which mounts syringes of a rear loadable type. Preferably an alternative head is provided that accepts front loadable syringes. The mounting head includes an opening and a moveable syringe holder that preferably pivots open to receive a syringe from the back of the holder and pivots closed to orient the rear of the syringe over the ram. The holder has a slot therethrough having a width sufficient to permit an injection tube attached to the syringe nozzle to be moved transversely through the slot to permit the syringe to be removed from the holder without disconnecting the tube from the orifice of the syringe and without withdrawing the tip of the tube rearwardly through the opening. The holder preferably includes a replaceable insert configured to snugly support a rear loadable syringe of a given configuration. One insert is preferably provided in the form of a pressure sleeve configured to support a syringe during high pressure use. The head has a locking mechanism that locks the syringe to the injector, couples the syringe plunger to the ram, locks and releases the head and locks the holder in operating position.
摘要翻译：提供一种动力注射器，用于将来自可更换注射器的流体和通过注射管注射到动物体内。注射器包括一个或多个操作者可拆卸和可互换的注射器安装头，其中至少一个安装了后部可装载型的注射器。优选地，提供了可接受前装载注射器的替代头部。安装头包括开口和可移动的注射器保持器，其优选地枢转打开以从保持器的后部接收注射器并且枢转关闭以将注射器的后部定向在压头上。保持器具有穿过其中的狭槽，其具有足以允许附接到注射器喷嘴的注射管横向穿过狭槽的宽度的宽度，以允许将注射器从保持器移除而不将管与注射器的孔分离而不退出管的尖端向后穿过开口。保持器优选地包括构造成紧密地支撑给定构造的后装载式注射器的可更换插入件。一个插入件优选地设置成压力套筒的形式，构造成在高压使用期间支撑注射器。头部具有将注射器锁定到注射器的锁定机构，将注射器柱塞连接到冲头，锁定并释放头部并将保持器锁定在操作位置。

34. 发明授权

US5456670A Power injector for injecting fluid into animals 失效
标题翻译：用于将动物注射入动物的动力注射器
公开(公告)号：US5456670A
公开(公告)日：1995-10-10
申请号：US205710
申请日：1994-03-03
申请人： Charles Neer , Frank M. Fago , Paul E. Dieterlen , James H. Goethel
发明人： Charles Neer , Frank M. Fago , Paul E. Dieterlen , James H. Goethel
IPC分类号： A61D7/00 , A61M5/145 , A61M37/00
CPC分类号： A61M5/14546 , A61M2250/00 , A61M5/14566 , A61M5/1458 , Y10S128/01
摘要： An animal fluid injector is provided with a syringe guide, preferably in the form of a pressure jacket, having an open front end through which a replaceable disposable syringe is loadable into and unloadable from, thereby permitting replacement without retraction of the syringe plunger drive or disconnection of the injection tubing. The injector is provided with structure, preferably in the form of thread sections, which mates with cooperating structure on the syringe, to connect and lock the syringe to the injector, preferably by rotational motion of, preferably, less than a full turn, of for example, 90.degree.. In the illustrated embodiment, the structure is at the front end of the guide or at the front periphery of a jacket to connect to threads on a pressure restraining front end of the syringe. A mechanism in the injector, which includes, for example, a key on cam ring provided with a lever that is preferably manually operable with one hand of an operator, interacts with structure such asymmetrically spaced notches on the back end of the syringe to, for example, rotate the syringe and simultaneously translate or rotate a coupling on the syringe plunger into and out of engagement with jaws provided of a plunger drive in the injector.
摘要翻译：动物流体注射器设置有优选为压力套形式的注射器引导件，其具有敞开的前端，可更换的一次性注射器通过该前端可装载和卸载，从而允许更换而不缩回注射器柱塞驱动器或断开的注射管。注射器设置有优选地以螺纹部分的形式的结构，其与注射器上的协作结构配合，以将注射器连接和锁定到注射器，优选地通过优选地小于整圈的旋转运动来进行例如90°。在所示的实施例中，结构位于导向器的前端或护套的前周边处，以连接到注射器的压力限制前端上的螺纹。注射器中的机构，其包括例如设置有杠杆的凸轮环上的键，其优选地由操作者的一只手可手动操作，与注射器的后端上的这种不对称间隔开的切口相互作用，用于例如，旋转注射器并且同时将注射器柱塞上的联接器平移或旋转进入和离开与注射器中的柱塞驱动器提供的夹爪接合。

35. 发明授权

US08932255B1 Methods for using front-loading medical fluid injector 有权
标题翻译：使用前装药液注射器的方法
公开(公告)号：US08932255B1
公开(公告)日：2015-01-13
申请号：US11677946
申请日：2007-02-22
申请人： Frank M. Fago , Robert Ziemba , Gary S. Wagner
发明人： Frank M. Fago , Robert Ziemba , Gary S. Wagner
IPC分类号： A61M1/00
CPC分类号： A61M5/14546 , A61M5/14566
摘要： Various sealing structures are used in a front-loading injector, for preventing leakage of spilled fluid from an external surface of a syringe into the vicinity of the drive ram. For example, a sealing gasket may be incorporated into the front face of the injector housing, for mating to the rearward circular edge of the cylindrical body of a syringe. Alternatively, sealing and locking functions may be performed by a single structure on the rearward end of the syringe. Further, leakage may be prevented by including a non-planar sealing flange on the syringe, positioned on the syringe forward of the locking structure, or by a two-piece structure, including a syringe and a separate leakage stopping washer for surrounding the syringe to halt the flow of fluid along the exterior of the syringe. (As part of this aspect, or as an independent feature, the syringe may include an annularly discontinuous flange forward of the locking structure, for providing mechanical support for the syringe against the injector.) Alternatively, an iris-like structure may be incorporated into the front surface of the injector, for closing about the syringe upon insertion of the syringe into the injector.
摘要翻译：在前装载注射器中使用各种密封结构，用于防止溢出的流体从注射器的外表面泄漏到驱动柱塞的附近。例如，密封衬垫可以并入到注射器壳体的前表面中，用于与注射器的圆柱形主体的后圆形边缘配合。或者，密封和锁定功能可以通过注射器后端上的单个结构来执行。此外，可以通过在注射器上包括位于注射器前方的锁定结构的注射器上的非平面密封凸缘或包括注射器的两件式结构，以及用于将注射器包围的单独的泄漏停止垫圈来防止泄漏停止沿着注射器外部的流体流动。（作为该方面的一部分，或作为独立特征，注射器可以包括锁定结构前面的环形不连续的凸缘，用于为注射器提供针对注射器的机械支撑。）或者，可将虹膜状结构并入注射器的前表面，用于在将注射器插入注射器时围绕注射器闭合。

36. 发明授权

US08864712B1 Spring loaded medical fluid injector assembly 有权
标题翻译：弹簧式医用液体注射器总成
公开(公告)号：US08864712B1
公开(公告)日：2014-10-21
申请号：US11677926
申请日：2007-02-22
申请人： Frank M. Fago , Robert Ziemba , Gary S. Wagner
发明人： Frank M. Fago , Robert Ziemba , Gary S. Wagner
IPC分类号： A61M1/00
CPC分类号： A61M5/14546 , A61M5/14566
摘要： Various sealing structures are used in a front-loading injector, for preventing leakage of spilled fluid from an external surface of a syringe into the vicinity of the drive ram. For example, a sealing gasket may be incorporated into the front face of the injector housing, for mating to the rearward circular edge of the cylindrical body of a syringe. Alternatively, sealing and locking functions may be performed by a single structure on the rearward end of the syringe. Further, leakage may be prevented by including a non-planar sealing flange on the syringe, positioned on the syringe forward of the locking structure, or by a two-piece structure, including a syringe and a separate leakage stopping washer for surrounding the syringe to halt the flow of fluid along the exterior of the syringe. (As part of this aspect, or as an independent feature, the syringe may include an annularly discontinuous flange forward of the locking structure, for providing mechanical support for the syringe against the injector.) Alternatively, an iris-like structure may be incorporated into the front surface of the injector, for closing about the syringe upon insertion of the syringe into the injector.
摘要翻译：在前装载注射器中使用各种密封结构，用于防止溢出的流体从注射器的外表面泄漏到驱动柱塞的附近。例如，密封衬垫可以并入到注射器壳体的前表面中，用于与注射器的圆柱形主体的后圆形边缘配合。或者，密封和锁定功能可以通过注射器后端上的单个结构来执行。此外，可以通过在注射器上包括位于注射器前方的锁定结构的注射器上的非平面密封凸缘或包括注射器的两件式结构，以及用于将注射器包围的单独的泄漏停止垫圈来防止泄漏停止沿着注射器外部的流体流动。（作为该方面的一部分，或作为独立特征，注射器可以包括锁定结构前面的环形不连续的凸缘，用于为注射器提供针对注射器的机械支撑。）或者，可将虹膜状结构并入注射器的前表面，用于在将注射器插入注射器时围绕注射器闭合。

37. 发明授权

US08597246B1 Front loaded medical fluid syringe mounting 有权
标题翻译：前装药液注射器安装
公开(公告)号：US08597246B1
公开(公告)日：2013-12-03
申请号：US11738925
申请日：2007-04-23
申请人： Frank M. Fago , Robert Ziemba , Gary S. Wagner
发明人： Frank M. Fago , Robert Ziemba , Gary S. Wagner
IPC分类号： A61M37/00
CPC分类号： A61M5/14546 , A61M5/14566
摘要： Various sealing structures are used in a front-loading injector, for preventing leakage of spilled fluid from an external surface of a syringe into the vicinity of the drive ram. For example, a sealing gasket may be incorporated into the front face of the injector housing, for mating to the rearward circular edge of the cylindrical body of a syringe. Alternatively, sealing and locking functions may be performed by a single structure on the rearward end of the syringe. Further, leakage may be prevented by including a non-planar sealing flange on the syringe, positioned on the syringe forward of the locking structure, or by a two-piece structure, including a syringe and a separate leakage stopping washer for surrounding the syringe to halt the flow of fluid along the exterior of the syringe. (As part of this aspect, or as an independent feature, the syringe may include an annularly discontinuous flange forward of the locking structure, for providing mechanical support for the syringe against the injector.) Alternatively, an iris-like structure may be incorporated into the front surface of the injector, for closing about the syringe upon insertion of the syringe into the injector.
摘要翻译：在前装载注射器中使用各种密封结构，用于防止溢出的流体从注射器的外表面泄漏到驱动柱塞的附近。例如，密封衬垫可以并入到注射器壳体的前表面中，用于与注射器的圆柱形主体的后圆形边缘配合。或者，密封和锁定功能可以通过注射器后端上的单个结构来执行。此外，可以通过在注射器上包括位于注射器前方的锁定结构的注射器上的非平面密封凸缘或包括注射器的两件式结构，以及用于将注射器包围的单独的泄漏停止垫圈来防止泄漏停止沿着注射器外部的流体流动。（作为该方面的一部分，或作为独立特征，注射器可以包括锁定结构前面的环形不连续的凸缘，用于为注射器提供针对注射器的机械支撑。）或者，可将虹膜状结构并入注射器的前表面，用于在将注射器插入注射器时围绕注射器闭合。

38. 发明申请

US20130245439A1 Medical Fluid Injector System 有权
标题翻译：医用流体注射器系统
公开(公告)号：US20130245439A1
公开(公告)日：2013-09-19
申请号：US13988800
申请日：2011-11-21
申请人： James R. Small , Jeffrey A. Perkins , Frank M. Fago , Mark Jon Glenn
发明人： James R. Small , Jeffrey A. Perkins , Frank M. Fago , Mark Jon Glenn
IPC分类号： A61M5/20
CPC分类号： A61M5/2066 , A61B6/548 , A61M5/1407 , A61M5/14546 , A61M5/16827 , A61M2005/14553 , A61M2205/502
摘要： A medical fluid injector system (450) is disclosed that may utilize one or more of flow rate determination logic (130), injection volume determination logic (132), display control logic (134), drive ram motion control logic (136), and pressure monitoring logic (138). The flow rate determination logic (130), injection volume determination logic (132), and display control logic (134) each may utilize a concentration input (172, 192, 202) to calculate flow rates, injection volumes, and generate multi-color graphics, respectively, for a simultaneous injection configuration. The drive ram motion control logic (136) may utilize both a target pressure and a monitored pressure to derive a velocity for advancing a drive ram. The pressure monitoring logic (138) may provide a monitored pressure value for the drive ram control logic (136), where this monitored pressure value may be derived from the input power being used to advance a drive ram and the drive ram velocity.
摘要翻译：公开了一种医疗流体注射器系统（450），其可以利用流量确定逻辑（130），注射体积确定逻辑（132），显示控制逻辑（134），驱动柱塞运动控制逻辑（136）中的一个或多个，以及压力监控逻辑（138）。流量确定逻辑（130），喷射量确定逻辑（132）和显示控制逻辑（134）各自可以利用浓度输入（172,192,202）来计算流速，喷射体积并产生多色图形，分别用于同时注入配置。驱动柱塞运动控制逻辑（136）可以利用目标压力和监视的压力来导出用于推进驱动柱塞的速度。压力监测逻辑（138）可以为驱动液压控制逻辑（136）提供监控的压力值，其中该监测的压力值可以从用于推进驱动柱塞的输入功率和驱动柱塞速度导出。

39. 发明授权

US08439863B2 Methods for controlling medical fluid injections 有权
标题翻译：控制医用液体注射的方法
公开(公告)号：US08439863B2
公开(公告)日：2013-05-14
申请号：US12445501
申请日：2008-04-28
申请人： Frank M. Fago , James E. Knipfer
发明人： Frank M. Fago , James E. Knipfer
IPC分类号： A61M31/00
CPC分类号： A61M31/005 , A61B6/481 , A61B6/504 , A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/172 , A61M2005/14208 , A61M2205/3362 , A61M2205/6018 , A61M2205/6054 , A61M2205/70
摘要： The present invention is directed to control of medical fluid injection systems. For instance, in some embodiments, an injection protocol may be initiated, and an actual flow rate of the medical fluid utilized in the injection protocol may be adjusted based, at least in part, on an inherent system elasticity of the injection system.
摘要翻译：本发明涉及药液注射系统的控制。例如，在一些实施例中，可以启动注射方案，并且可以至少部分地基于注射系统的固有系统弹性来调整在注射方案中使用的医用流体的实际流速。

40. 发明授权

US08343102B2 Fluid driven medical injectors 有权
公开(公告)号：US08343102B2
公开(公告)日：2013-01-01
申请号：US12830546
申请日：2010-07-06
申请人： Gary S. Wagner , Frank M. Fago , Peter Staats , Dane Battiato
发明人： Gary S. Wagner , Frank M. Fago , Peter Staats , Dane Battiato
IPC分类号： A61M37/00 , A61M1/00 , A61K9/22 , F04B39/06
CPC分类号： A61B5/055 , A61M5/007 , A61M5/14216 , A61M5/14228 , A61M5/14526 , A61M5/1454 , A61M5/16827 , A61M39/08 , A61M2005/14513
摘要： Some injectors of the invention may include a fluid drive responsive to pressure of a working fluid (e.g., liquid, pneumatic, or both) to impart a sequence of forces to drive a delivery device (e.g., a syringe) to deliver a medical fluid (e.g., a contrast agent, a radiopharmaceutical, a drug, or a combination thereof). Some injectors may include a multimedia tube configured to pass a working fluid (e.g., air) and a light signal (e.g., infrared). Some injectors may include a peristaltic drive responsive to pressure of a working fluid.

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