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31. 发明申请

WO2013010293A1 A SHEET FORMING TOOL AND A METHOD FOR THE MANUFACTURE OF A CORRUGATED SHEET 审中-公开
标题翻译：一种成型工具及其制造方法
公开(公告)号：WO2013010293A1
公开(公告)日：2013-01-24
申请号：PCT/CN2011/001197
申请日：2011-07-21
申请人： SULZER CHEMTECH AG , CHIN, Kimwah , SHENG, Xiaolei , LI, Yang , CHOTHUTSHANG, Lhoden
发明人： CHIN, Kimwah , SHENG, Xiaolei , LI, Yang , CHOTHUTSHANG, Lhoden
IPC分类号： B21D13/02 , B31F1/20 , B29C53/22 , B29C53/24
CPC分类号： B21D13/02 , B21D13/10 , B29C53/24 , B31F1/247 , Y10T428/12354
摘要： A sheet forming tool (1) for the manufacture of a corrugated sheet has a lower tool element (40) and an upper tool element (50), each of the upper tool element and the lower tool element having a front side (23, 33, 41) and a rear side (25, 35, 42). The lower tool element (40) comprises a first base element (2, 4, 6, 8) and a first finger element (3, 5, 7, 9) projecting from said first base element (2, 4, 6, 8). The first finger element (3, 5, 7, 9) forms a first ridge (22, 24, 26, 28) for forming a corrugation peak in the sheet. The upper tool element (50) comprises a second base element (12, 14) and a second finger element (13, 15) projecting from said second base element (12, 14), the second finger element (13, 15) forming a second ridge (32, 34) for forming a corrugation trough in said sheet. The first ridge (22, 24, 26, 28) is arranged opposite to the second ridge (32, 34) and the first ridge (22, 24, 26, 28) is offset from the second ridge (32, 34) so as to allow for an engagement of the first finger element (3, 5, 7, 9) and the second finger element (13, 15) in an engaged position. Each of the first ridge (22, 24, 26, 28) and second ridge (32, 34) comprises a main portion (20) and an end portion (11, 21) and the angle β (36) between each of the first ridge (22, 24, 26, 28) and second ridge (32, 34) in the main portion (20) and the corresponding front side (23, 33, 41 ) is at least partly different from the angle between each of the first ridge (22, 24, 26, 28) and second ridge (32, 34) in the end portion (11, 21) and the corresponding front side and a space is provided between the first finger element (3, 5, 7, 9) and the neighbouring second finger element (13, 15) in the engaged position.
摘要翻译：用于制造波纹片的片材成形工具（1）具有下部工具元件（40）和上部工具元件（50），上部工具元件和下部工具元件中的每一个具有前侧（23,33 ，41）和后侧（25,35,42）。下部工具元件（40）包括第一基座元件（2,4,6,8）和从所述第一基座元件（2,4,6,8）伸出的第一指状元件（3,5,7,9）。第一指状元件（3,5,7,9）形成用于在片材中形成波纹峰的第一脊（22,24,26,28）。上部工具元件（50）包括第二基本元件（12,14）和从所述第二基础元件（12,14）突出的第二指状元件（13,15），所述第二指状元件（13,15）形成用于在所述片材中形成波纹槽的第二脊部（32,34）。第一脊（22,24,26,28）与第二脊（32,34）相对设置，第一脊（22,24,26,28）从第二脊（32,34）偏移，以便以允许第一手指元件（3,5,7,9）和第二手指元件（13,15）接合在接合位置。第一脊部（22,24,26,28）和第二脊部（32,34）中的每一个包括主要部分（20）和端部部分（11,21），并且第一脊部（22,24,26,28）和第二脊部主部分（20）中的脊（22,24,26,28）和第二脊（32,34）与相应的前侧（23,33,41）之间的角度至少部分地不同于第一在第一手指元件（3,5,7,9）之间设置有端部（11,21）中的脊部（22,24,26,28）和第二脊部（32,34）和相应的前侧以及空间，）和相邻的第二手指元件（13,15）处于接合位置。

32. 发明申请

WO2011130417A2 HUMAN FGF RECEPTOR AND β-KLOTHO BINDING PROTEINS 审中-公开
标题翻译：人FGF受体和ß-KLOTHO结合蛋白
公开(公告)号：WO2011130417A2
公开(公告)日：2011-10-20
申请号：PCT/US2011/032333
申请日：2011-04-13
申请人： AMGEN INC. , FACHINI, Roger , FOLTZ, Ian , HAN, Seog Joon , HARRIS, Susie Miki , HU, Shaw-Fen Sylvia , KING, Chadwick Terence , LI, Yang , LU, Ji , MICHAELS, Mark Leo , SUN, Jeonghoon
发明人： FACHINI, Roger , FOLTZ, Ian , HAN, Seog Joon , HARRIS, Susie Miki , HU, Shaw-Fen Sylvia , KING, Chadwick Terence , LI, Yang , LU, Ji , MICHAELS, Mark Leo , SUN, Jeonghoon
IPC分类号： C07K16/28
CPC分类号： A61K39/3955 , C07K16/2863 , C07K16/40 , C07K2317/21 , C07K2317/31 , C07K2317/32 , C07K2317/75 , C07K2317/92 , C07K2319/75
摘要： The present invention provides compositions and methods relating to or derived from antigen binding proteins and antigen binding protein-FGF21 fusions that specifically bind to β-Klotho, or β-Klotho and one or more of FGFR1c, FGFR2c, FGFR3c, and FGFR4. In some embodiments the antigen binding proteins and antigen binding protein-FGF21 fusions induce FGF21-like signaling. In some embodiments, an antigen binding protein or antigen binding protein-FGF21 fusion antigen binding component is a fully human, humanized, or chimeric antibody, binding fragments and derivatives of such antibodies, and polypeptides that specifically bind to β-Klotho, or β-Klotho and one or more of FGFR1c, FGFR2c, FGFR3c, and FGFR4. Other embodiments provide nucleic acids encoding such antigen binding proteins and antigen binding protein-FGF21 fusions, and fragments and derivatives thereof, and polypeptides, cells comprising such polynucleotides, methods of making such antigen binding proteins and antigen binding protein-FGF21 fusions, and fragments and derivatives thereof, and polypeptides, and methods of using such antigen binding proteins and antigen binding protein-FGF21 fusions, fragments and derivatives thereof, and polypeptides, including methods of treating or diagnosing subjects suffering from type 2 diabetes, obesity, NASH, metabolic syndrome and related disorders or conditions.
摘要翻译：本发明提供与抗原结合蛋白和特异性结合ß-Klotho或ß-Klotho以及FGFR1c，FGFR2c，FGFR3c和FGFR4中的一种或多种的抗原结合蛋白和抗原结合蛋白-FGF21融合物相关或衍生的组合物和方法。在一些实施方案中，抗原结合蛋白和抗原结合蛋白FGF21融合物诱导FGF21样信号传导。在一些实施方案中，抗原结合蛋白或抗原结合蛋白-FGF21融合抗原结合组分是完全人，人源化或嵌合抗体，这种抗体的结合片段和衍生物，以及特异性结合ß-Klotho或ß- Klotho和FGFR1c，FGFR2c，FGFR3c和FGFR4中的一种或多种。其他实施方案提供编码这种抗原结合蛋白和抗原结合蛋白-FGF21融合体的核酸，及其片段和衍生物，以及多肽，包含这种多核苷酸的细胞，制备这种抗原结合蛋白的方法和抗原结合蛋白-FGF21融合物，其衍生物和多肽，以及使用这种抗原结合蛋白和抗原结合蛋白-FGF21融合体，其片段和衍生物和多肽的方法，包括治疗或诊断患有2型糖尿病，肥胖症，NASH，代谢综合征和相关疾病或病症。

33. 发明申请

WO2010054087A2 VHF ENERGIZED PLASMA DEPOSITION PROCESS FOR THE PREPARATION OF THIN FILM MATERIALS 审中-公开
标题翻译：用于制备薄膜材料的VHF激发等离子体沉积工艺
公开(公告)号：WO2010054087A2
公开(公告)日：2010-05-14
申请号：PCT/US2009/063408
申请日：2009-11-05
申请人： UNITED SOLAR OVONIC LLC , XU, Xixiang , BEGLAU, David, Alan , YUE, Guozhen , YAN, Baojie , LI, Yang , JONES, Scott , GUHA, Subhendu , YANG, Chi
发明人： XU, Xixiang , BEGLAU, David, Alan , YUE, Guozhen , YAN, Baojie , LI, Yang , JONES, Scott , GUHA, Subhendu , YANG, Chi
IPC分类号： H01L21/205
CPC分类号： H01L21/02532 , C23C16/22 , C23C16/5096 , H01J37/32091 , H01J37/32761 , H01J2237/2001 , H01L21/02592 , H01L21/0262
摘要： A VHF energized plasma deposition process wherein a process gas is decomposed in a plasma so as to deposit the thin film material onto a substrate, is carried out at process gas pressures which are in the range of 0.5-2.0 torr, with substrate temperatures that do not exceed 300° C, and substrate-cathode spacings in the range of 10-50 millimeters. Deposition rates are at least 5 angstroms per second. The present method provides for the high speed deposition of semiconductor materials having a quality at least equivalent to materials produced at a much lower deposition rate.
摘要翻译：其中工艺气体在等离子体中分解以便将薄膜材料沉积到衬底上的VHF激励等离子体沉积工艺是在工艺气体压力下进行的， 2.0托，基板温度不超过300℃; C，衬底 - 阴极间距为10-50毫米。沉积速率至少为每秒5埃。本发明的方法提供了半导体材料的高速沉积，其质量至少等同于以低得多的沉积速率生产的材料。

34. 发明申请

WO2004016982A2 ONBOARD HYDROGEN STORAGE UNIT WITH HEAT TRANSFER SYSTEM FOR USE IN A HYDROGEN POWERED VEHICLE 审中-公开
标题翻译：带氢传动系统的氢能存储单元，用于氢动力车辆
公开(公告)号：WO2004016982A2
公开(公告)日：2004-02-26
申请号：PCT/US2003/025135
申请日：2003-08-11
申请人： TEXACO OVONIC HYDROGEN SYSTEMS LLC , MYASNIKOV, Vitaliy , YOUNG, Rosa , LI, Yang , OVSHINSKY, Stanford, R.
发明人： MYASNIKOV, Vitaliy , YOUNG, Rosa , LI, Yang , OVSHINSKY, Stanford, R.
IPC分类号： F17C
CPC分类号： F17C6/00 , B01D53/02 , C01B3/0005 , F17C9/00 , F17C11/005 , F17C2221/012 , F17C2227/0323 , F17C2227/0355 , F17C2260/02 , F17C2265/065 , F17C2265/066 , F17C2270/0168 , Y02E60/321 , Y02E60/324
摘要： An onboard hydrogen storage unit with heat transfer system for a hydrogen powered vehicle. The system includes a hydrogen storage vessel containing a hydrogen storage alloy configured to receive a stream of hydrogen and provide hydrogen for use in powering a vehicle. During refueling a cooling/heating loop is used to remove the heat of hydride formation from the hydrogen storage alloy and during operation of the vehicle the heating/cooling loop is used to supply heat to the hydrogen storage alloy to aid in hydrogen desorption.
摘要翻译：具有用于氢动力车辆的传热系统的机载氢存储单元。该系统包括含有储氢合金的氢存储容器，该储氢合金构造成接收氢气流并提供用于为车辆供电的氢气。在加油期间，使用冷却/加热回路来从储氢合金中除去氢化物形成的热量，并且在车辆操作期间，加热/冷却回路用于向储氢合金供热以辅助氢解吸。

35. 发明申请

WO2020046633A1 INDOOR HUMAN DETECTION AND MOTION TRACKING USING LIGHT REFLECTIONS 审中-公开
公开(公告)号：WO2020046633A1
公开(公告)日：2020-03-05
申请号：PCT/US2019/047194
申请日：2019-08-20
申请人： OSRAM GMBH , ABBOUD, Khadige , LI, Yang , BERMUDEZ, Sergio
发明人： ABBOUD, Khadige , LI, Yang , BERMUDEZ, Sergio
IPC分类号： G01S17/02 , G01S17/50 , G08B13/18
摘要： Techniques are disclosed for detecting human presence and tracking motion within a given area using light reflections. Activity is detected by receiving light encoded with source-identifying data reflected from the area and sensing changes, caused by human presence in the area, from a previously established baseline in the light reflection profile for the area. The baseline is updated over time based on human movement and/or as the area changes. Location-indicative changes in the current baseline that are greater than a certain threshold indicate a change in occupancy state of that location. In some embodiments, lightguides are used to define a specific field-of-view for the sensors. The combination of a known field-of-view and a known source of reflected light allows location of each occupant's activity to be tracked within the area. Occupancy can be detected or inferred based on activity tracked entering the area followed by lack of an exit event.

36. 发明申请

WO2020041103A1 AUTOMATED LUMINAIRE COMMISSIONING USING COMPUTER VISION AND LIGHT-BASED COMMUNICATIONS 审中-公开
公开(公告)号：WO2020041103A1
公开(公告)日：2020-02-27
申请号：PCT/US2019/046740
申请日：2019-08-16
申请人： OSRAM GMBH , LI, Yang , ABBOUD, Khadige , BERMUDEZ, Sergio , ADLER, Helmar
发明人： LI, Yang , ABBOUD, Khadige , BERMUDEZ, Sergio , ADLER, Helmar
IPC分类号： H05B37/02 , H04B10/116
摘要： Aspects of the present disclosure include systems and methods for automated luminaire commissioning using computer vision and light-based communications ("LCom"). In some examples, locations of an installation of luminaires can be measured and recorded with a mobile commissioning device equipped with an image capture device and image processing and simultaneous localization and mapping software.

37. 发明申请

WO2018209046A1 SNAPSHOT PHOTOACOUSTIC PHOTOGRAPHY USING AN ERGODIC RELAY 审中-公开
公开(公告)号：WO2018209046A1
公开(公告)日：2018-11-15
申请号：PCT/US2018/032007
申请日：2018-05-10
申请人： WASHINGTON UNIVERSITY , WANG, Lihong , LI, Yang , LI, Lei
发明人： WANG, Lihong , LI, Yang , LI, Lei
IPC分类号： G01N29/22
CPC分类号： G01N29/2418 , G01N21/1702 , G01N21/274 , G01N29/22 , G01N2021/1706
摘要： A photoacoustic imaging system is disclosed that includes an ergodic relay coupled optically to a light source configured to produce a light pulse and further coupled acoustically to a transducer. The ergodic relay is further configured to direct at least two PA signals to the transducer. Each of the at least two PA signals are produced at different positions within the field of view of the object to be imaged in response to illumination by a single light pulse. The transducer detects each of the at least two PA signals after each of at least two delays that correspond to the position at which each PA signal was produced.

38. 发明申请

WO2018045266A1 METHODS AND COMPOSITIONS FOR TREATING CHRONIC GRANULOMATOUS DISEASE 审中-公开
标题翻译：治疗慢性粒细胞疾病的方法和组合物
公开(公告)号：WO2018045266A1
公开(公告)日：2018-03-08
申请号：PCT/US2017/049815
申请日：2017-09-01
申请人： LI, Senlin , CLARK, Robert, A. , CHEN, Cang , LI, Yang
发明人： LI, Senlin , CLARK, Robert, A. , CHEN, Cang , LI, Yang
IPC分类号： A61K35/28 , A61K48/00 , A61M1/38 , C12N15/86 , C12N5/071 , C12N5/0789 , C12N5/0783
CPC分类号： A61K35/28 , A01K67/0276 , A01K2227/105 , A01K2267/0306 , A61K38/193 , C12N15/86 , C12N2740/16043
摘要： Certain embodiments are directed to compositions and methods for non-cytotoxic hematopoietic stem cell transplantation for the treatment of chronic granulomatous disease
摘要翻译：某些实施方案涉及用于治疗慢性肉芽肿性疾病的非细胞毒性造血干细胞移植的组合物和方法

39. 发明申请

WO2013078091A1 COLLAGEN MIMETIC PEPTIDES FOR TARGETING COLLAGEN STRANDS FOR IN VITRO AND IN VIVO IMAGING AND THERAPEUTIC USE 审中-公开
标题翻译：胶原纤维素胶束用于体外和体内成像和治疗用途中的胶原纤维
公开(公告)号：WO2013078091A1
公开(公告)日：2013-05-30
申请号：PCT/US2012/065551
申请日：2012-11-16
申请人： THE JOHNS HOPKINS UNIVERSITY , YU, Michael , LI, Yang , SUMMERFIELD, Daniel , WANG, Allen Yi-Lan , FOSS, Catherine A. , POMPER, Martin , GUNASEKAR, Susheel K.
发明人： YU, Michael , LI, Yang , SUMMERFIELD, Daniel , WANG, Allen Yi-Lan , FOSS, Catherine A. , POMPER, Martin , GUNASEKAR, Susheel K.
IPC分类号： C07K14/78 , C07K17/14 , A61K38/39 , A61P19/00
CPC分类号： A61K38/39 , A61K38/00 , C07K14/78 , G01N33/6887 , Y02P20/55
摘要： The present invention provides both a caged collagen mimetic peptide (CCMP) having the formula: L-S-Z m -[Gly-X-Y] n - L Gly -X-Y-[Gly-X-Y] n ; wherein L is one or more detectable moieties and/or biologically active compounds; S is one or more spacer molecules; Z m is any amino acid where m is an integer of 1 to 10; X is proline or modified proline; Y is proline or modified proline; Gly is glycine; n is an integer from 1 to 20; and L Gly is a glycine covalently linked to a cage moiety comprising a labile protecting group, as well as a collagen mimetic peptides lacking the labile protecting group (CMP). The inventions are useful for binding collagen and denatured collagen and/or gelatin both in vitro and in vivo, and are useful for targeting any organ or tissue where collagen is present, and can be used for research and diagnostic imaging (both in vivo and in vitro) and also for in vivo therapeutic applications.
摘要翻译：本发明提供具有下式的笼状胶原模拟肽（CCMP）：L-S-Zm- [Gly-X-Y] n-LGly -X-Y- [Gly-X-Y] n; 其中L是一个或多个可检测部分和/或生物活性化合物; S是一个或多个间隔分子; Zm是任何氨基酸，其中m是1至10的整数; X是脯氨酸或改性脯氨酸; Y是脯氨酸或改性脯氨酸; Gly是甘氨酸; n为1〜20的整数，并且LGly是与包含不稳定保护基团的笼部分共价连接的甘氨酸，以及缺乏不稳定保护基团（CMP）的胶原模拟肽。本发明可用于在体外和体内结合胶原和变性胶原和/或明胶，并且可用于靶向存在胶原的任何器官或组织，并且可用于研究和诊断成像（在体内和体外），也用于体内治疗应用。

40. 发明申请

WO2012115823A1 TOUCH GESTURES FOR REMOTE CONTROL OPERATIONS 审中-公开
标题翻译：触摸式遥控操作
公开(公告)号：WO2012115823A1
公开(公告)日：2012-08-30
申请号：PCT/US2012/025093
申请日：2012-02-14
申请人： GOOGLE INC. , LI, Yang , LU, Hao
发明人： LI, Yang , LU, Hao
IPC分类号： G06F3/048
CPC分类号： G06F3/0482 , G06F3/04883 , H04N21/4126 , H04N21/42224
摘要： In general, this disclosure describes techniques for providing a user of a first computing device (e.g., a mobile device) with the ability to utilize the first computing device to control a second computing device (e.g., a television). Specifically, the techniques of this disclosure may, in some examples, allow the user to use drawing gestures on a mobile computing device to remotely control and operate the second computing device. Using a presence-sensitive user interface device (e.g., a touch screen), the user may use drawing gestures to indicate characters associated with operations and commands to control the second computing device.
摘要翻译：通常，本公开描述了用于向第一计算设备（例如，移动设备）的用户提供具有利用第一计算设备来控制第二计算设备（例如，电视）的能力的技术。具体来说，在一些示例中，本公开的技术可以允许用户在移动计算设备上使用绘图手势来远程控制和操作第二计算设备。使用存在敏感的用户界面设备（例如，触摸屏），用户可以使用绘图手势来指示与操作相关联的字符和用于控制第二计算设备的命令。

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