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31. 发明申请

US20060122621A1 Bone treatment systems and methods 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20060122621A1
公开(公告)日：2006-06-08
申请号：US11208448
申请日：2005-08-20
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/36
CPC分类号： A61B17/8836 , A61B17/8811 , A61B17/8822 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61F2/44
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of bone cement introduced into the interior of a vertebra. An exemplary system utilizes Rf energy in combination a conductive bone cement for polymerizing the inflow plume to control the geometry of the fill material and the application of force caused by inflows of cement. In another embodiment, a method of treating bone includes utilizing a controller to control (i) bone cement inflow parameters and (ii) energy delivery parameters selectively modify the viscosity of a selected portion of bone cement as it is introduced. A system for treating bone includes an introducer for delivering bone and an energy source selectively coupleable to the bone cement to alter the viscosity of the fill material as it flows out of the introducer. One method includes pulsing the inflows of bone cement and further applying pulsed aspiration forces to the interior of the vertebra to relieve interior pressures to prevent emboli from migrating into the venous system.
摘要翻译：本发明在某些实施例中涉及用于治疗诸如椎体压缩性骨折的骨整形术程序的医疗装置。更具体地，本发明的实施例涉及通过控制引入到椎骨内部的骨粘固剂的几何形状来可控地恢复椎体高度的器械和方法。一个示例性系统利用Rf能量组合导电骨水泥，用于聚合流入羽流以控制填充材料的几何形状以及由水泥流入引起的力的施加。在另一个实施方案中，治疗骨的方法包括利用控制器来控制（i）骨水泥流入参数和（ii）能量递送参数在其被引入时选择性地改变所选择的骨水泥部分的粘度。用于治疗骨的系统包括用于输送骨的导引器和选择性地可耦合到骨粘固剂的能量源，以在填充材料流出导引器时改变填充材料的粘度。一种方法包括脉动骨水泥的流入，并进一步向椎骨内部施加脉冲抽吸力，以缓解内部压力，以防止栓塞进入静脉系统。

32. 发明申请

US20060111706A1 Electrosurgical working end for controlled energy delivery 有权
公开(公告)号：US20060111706A1
公开(公告)日：2006-05-25
申请号：US11315418
申请日：2005-12-21
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/00083
摘要： An electrosurgical working end for automatic modulation of active Rf density in a targeted tissue volume. The working end of the probe of the present invention defines a tissue-engagement surface of an elastomeric material with conductive elements that extend therethrough. In one embodiment, the expansion of the elastomeric material can de-couple the conductive elements from an interior electrode based temperature to modulate current flow. In another embodiment, the elastomeric material can couple and de-couple the conductive elements from an interior electrode based on engagement pressure to modulate current flow

33. 发明申请

US20060095138A1 Composites and methods for treating bone 审中-公开
标题翻译：复合材料和治疗骨的方法
公开(公告)号：US20060095138A1
公开(公告)日：2006-05-04
申请号：US11148973
申请日：2005-06-09
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/28
CPC分类号： A61B17/7095 , A61B17/68 , A61B17/686 , A61F2/28 , A61F2/30965 , A61F2/3662 , A61F2/44 , A61F2002/2817 , A61F2002/2835 , A61F2002/30006 , A61F2002/30011 , A61F2002/30023 , A61F2002/30069 , A61F2002/3008 , A61F2002/30092 , A61F2002/30224 , A61F2002/30583 , A61F2002/30677 , A61F2002/3085 , A61F2002/30957 , A61F2002/30971 , A61F2210/0014 , A61F2210/0085 , A61F2230/0069 , A61F2250/0015 , A61F2250/0018 , A61F2250/0023 , A61F2250/0034 , A61F2250/0098 , A61F2310/00353 , A61L27/50 , A61L2430/02
摘要： A system and method for treating bone abnormalities including vertebral compression fractures and the like. In one vertebroplasty method, a fill material is injected under high pressures into cancellous bone wherein the fill material includes a flowable bone cement component and an elastomeric polymer component that is carried therein. The elastomer component can further carry microscale or mesoscale reticulated elements. Under suitable injection pressures, the elastomeric component ultimately migrates within the flowable material to alter the apparent viscosity across the plume of fill material to accomplish multiple functions. For example, the differential in apparent viscosity across the fill material creates a broad load-distributing layer within cancellous bone for applying retraction forces to cortical bone endplates. The differential in apparent viscosity also transitions into a flow impermeable layer at the interface of cancellous bone and the flowable material to prevent extravasion of the flowable bone cement component.
摘要翻译：一种用于治疗包括椎骨压缩性骨折等骨骼异常的系统和方法。在一种椎体成形术方法中，将填充材料在高压下注射到松质骨中，其中填充材料包括可流动的骨粘固剂组分和其中携带的弹性体聚合物组分。弹性体组分可以进一步携带微米或中等尺寸的网状元件。在合适的注射压力下，弹性体组分最终在可流动材料内迁移以改变穿过填充材料的羽流的表观粘度，以实现多种功能。例如，穿过填充材料的表观粘度的差异在松质骨内产生宽的载荷分布层，用于将回缩力施加到皮质骨终板。表观粘度的差异也转变为松质骨和可流动材料的界面处的不透水层，以防止可流动的骨水泥组分的外渗。

34. 发明申请

US20060084969A1 Endovascular catheter and method of use 审中-公开
标题翻译：血管内导管及其使用方法
公开(公告)号：US20060084969A1
公开(公告)日：2006-04-20
申请号：US11199580
申请日：2005-08-08
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61B18/14
CPC分类号： A61B18/1482 , A61B18/1442 , A61B18/1492 , A61B2018/0022 , A61B2018/00351 , A61B2090/064
摘要： An electrosurgical medical device and method for treating cardiac arrhythmias. In one embodiment, an elongate catheter has a distal shaft end or balloon that carries an electrosurgical energy delivery surface comprising at least one electrode with a positive temperature coefficient of resistance (PTCR) surface and/or an electrode with a pressure sensitive variable resistance to provide a smart surface for controlling Rf current flow at the interface of electrosurgical surface and the tissue. The electrosurgical surface then can limit or modulate Rf energy delivery through the surface in response to the temperature of the tissue or the engagement pressure of the surface against the engaged tissue. In operation, the smart electrosurgical surface can prevent arcing at the electrode-tissue interface, and thus control ohmic heating to prevent tissue desiccation, charring and emboli formation.
摘要翻译：一种用于治疗心律失常的电外科医疗装置和方法。在一个实施例中，细长导管具有远端轴端或气囊，其携带电外科能量输送表面，其包括具有正温度系数电阻（PTCR）表面的至少一个电极和/或具有压敏可变电阻的电极，以提供用于控制电外科表面和组织界面处的Rf电流的智能表面。然后电外科表面可以响应于组织的温度或表面对接合组织的接合压力而限制或调节通过表面的Rf能量传递。在操作中，智能电外科表面可以防止电极 - 组织界面处的电弧，从而控制欧姆加热，以防止组织干燥，炭化和栓塞形成。

35. 发明申请

US20060084968A1 Electrosurgical instrument and method 有权
公开(公告)号：US20060084968A1
公开(公告)日：2006-04-20
申请号：US11199555
申请日：2005-08-08
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61B18/14 , A61F7/00 , A61F7/12
CPC分类号： A61B18/1492 , A61B18/1442 , A61B2018/00077 , A61B2018/00083 , A61B2018/00148 , A61B2018/00404 , A61B2018/0063 , A61B2018/00702 , A61B2018/00809 , A61B2090/064
摘要： An electrosurgical instrument and method for treating varicose veins. In one embodiment, an elongate catheter has a distal working end that carries an electrosurgical energy delivery surface comprising at least one electrode with a positive temperature coefficient of resistance (PTCR) surface and/or an electrode with a pressure sensitive variable resistance to provide a smart surface for controlling Rf current flow at the interface of electrosurgical surface and the tissue. The electrode surface then can limit or modulate Rf energy delivery through the surface in response to the temperature of the surface or the engagement pressure of the surface against the engaged tissue. In operation, the smart electrosurgical surface prevents arcing at the electrode-tissue interface, and thus controls ohmic heating to prevent tissue desiccation, charring and emboli formation.

36. 发明申请

US20050203507A1 Electrosurgical instrument and method of use 有权
标题翻译：电外科仪器及使用方法
公开(公告)号：US20050203507A1
公开(公告)日：2005-09-15
申请号：US11080101
申请日：2005-03-14
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61B18/14
CPC分类号： A61B18/1442
摘要： A particular embodiment of the invention provides an electrosurgical working end for performing high strength welding of tissue comprising a body having a tissue contacting energy delivery surface. The body includes pixel portions and non-pixel portions distributed within the tissue contacting surface. The pixel portions comprise a positive temperature coefficient of resistance (PTCR) material with at least one pixel portion configured to switch Rf current on and off in the at least one pixel portion responsive to tissue temperature adjacent the at least one pixel portion. The pixel portions can be configured to be coupled to an Rf current source such as an Rf generator. The pixelated energy delivery surfaces are capable of highly localized modulation of Rf energy application to the engaged tissue to create high strength tissue welds.
摘要翻译：本发明的一个具体实施方案提供了一种电外科工作端，用于对组织进行高强度焊接，包括具有组织接触能量输送表面的主体。主体包括分布在组织接触表面内的像素部分和非像素部分。像素部分包括正温度系数电阻（PTCR）材料，其中至少一个像素部分被配置成响应于与至少一个像素部分相邻的组织温度在至少一个像素部分中开启和关闭Rf电流。像素部分可以被配置为耦合到诸如Rf发生器的Rf电流源。像素化的能量传递表面能够对接合的组织进行Rf能量的高度局部调节，以产生高强度组织焊接。

37. 发明申请

US20080065083A1 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：US20080065083A1
公开(公告)日：2008-03-13
申请号：US11852067
申请日：2007-09-07
申请人： Csaba Truckai , Robert Luzzi , John Shadduck
发明人： Csaba Truckai , Robert Luzzi , John Shadduck
IPC分类号： A61B17/56 , A61B17/58 , A61M31/00
CPC分类号： A61B17/8811 , A61B17/3472 , A61B2017/349
摘要： The present invention relates in certain embodiments to systems for treating vertebral compression fractures. In one embodiment, an elongated sleeve defines a passageway therethrough, and has a threaded portion configured to engage bone. The sleeve includes a seal configured to allow instrument exchange through the passageway and into the interior of the vertebra to perform at least one medical procedure, such as injection of bone cement into the vertebral body.
摘要翻译：本发明在某些实施例中涉及用于治疗脊柱压缩性骨折的系统。在一个实施例中，细长套管限定穿过其中的通道，并且具有构造成接合骨的螺纹部分。套筒包括密封件，该密封件构造成允许通过通道进入器械的交换并进入椎骨的内部以执行至少一种医疗过程，例如将骨粘固剂注入椎体。

38. 发明申请

US20070129728A1 ELECTROSURGICAL INSTRUMENT 有权
标题翻译：静电仪
公开(公告)号：US20070129728A1
公开(公告)日：2007-06-07
申请号：US11673889
申请日：2007-02-12
申请人： Csaba Truckai , John Shadduck , Bruno Strul
发明人： Csaba Truckai , John Shadduck , Bruno Strul
IPC分类号： A61B18/14
CPC分类号： A61B18/1445 , A61B18/1442 , A61B2018/00077 , A61B2018/00083 , A61B2018/00125 , A61B2018/00148 , A61B2018/0016 , A61B2018/00404 , A61B2018/00601 , A61B2018/0063 , A61B2018/1412 , A61B2018/1455
摘要： An embodiment of the invention includes an electrosurgical jaw structure that carries cooperating PTC bodies in both series and parallel circuit components for controlled RF energy application to engaged tissue to effectively weld tissue.
摘要翻译：本发明的实施例包括电外科钳口结构，其在串联和并联电路部件中携带协作的PTC体，用于受控RF能量施加到接合组织以有效地焊接组织。

39. 发明授权

US07125409B2 Electrosurgical working end for controlled energy delivery 有权
标题翻译：电外科工作端可控能量输送
公开(公告)号：US07125409B2
公开(公告)日：2006-10-24
申请号：US11315418
申请日：2005-12-21
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61B18/12
CPC分类号： A61B18/1477 , A61B2018/00083
摘要： An electrosurgical working end for automatic modulation of active Rf density in a targeted tissue volume. The working end of the probe of the present invention defines a tissue-engagement surface of an elastomeric material with conductive elements that extend therethrough. In one embodiment, the expansion of the elastomeric material can de-couple the conductive elements from an interior electrode based temperature to modulate current flow. In another embodiment, the elastomeric material can couple and de-couple the conductive elements from an interior electrode based on engagement pressure to modulate current flow
摘要翻译：用于自动调节靶组织体积中的活性Rf密度的电外科工作端。本发明的探针的工作端限定弹性体材料的组织接合表面，其中导电元件延伸穿过其中。在一个实施例中，弹性体材料的膨胀可以将导电元件从基于内部电极的温度解耦，以调制电流。在另一个实施例中，弹性体材料可以基于接合压力将导电元件从内部电极耦合和解耦，以调制电流

40. 发明申请

US20060229628A1 Biomedical treatment systems and methods 审中-公开
标题翻译：生物医学治疗系统和方法
公开(公告)号：US20060229628A1
公开(公告)日：2006-10-12
申请号：US11242592
申请日：2005-10-03
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61B17/58
CPC分类号： A61B17/8858 , A61B17/70
摘要： An apparatus and method for distraction of tissue or bone in a surgery. A method comprises inserting into targeted tissue a distraction device configured with at least one phase transition extendable body. After deployment in a non-extended configuration, the physician applies a stimulus to the body or bodies to cause a liquid-to-vapor or solid-to-vapor phase transition within the body that extends the body in a fast event from the non-extended configuration to an extended configuration to thereby apply distraction forces to the targeted tissue. The extendable body is made of biocompatible materials having any suitable configuration. In one embodiment, the implant and system is used for reducing a vertebral compression fracture. The distraction system can be used to distribute forces over a selected region of strong cortical bone to restore vertebral height. Such a system can be dimensioned as a cylindrical, spherical, annular or part-annular construct for creating selected directional forces for moving apart cortical endplates.
摘要翻译：一种用于在手术中分散组织或骨骼的装置和方法。一种方法包括将配置有至少一个相变延伸体的牵引装置插入目标组织。在以非延伸配置部署之后，医生对身体或身体施加刺激，以引起身体内的液体至蒸汽或固体与汽相的相变，从而使身体在非快速事件中从非延伸构型延伸，延伸构型为延伸构型，从而向目标组织施加牵引力。可延伸体由具有任何合适结构的生物相容性材料制成。在一个实施例中，植入物和系统用于减少椎体压缩骨折。牵引系统可用于在强皮质骨的选定区域上分布力以恢复椎体高度。这种系统的尺寸可以是圆柱形，球形，环形或部分环形构造，用于产生用于移动分开的皮层终板的选定的方向力。

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