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31. 发明申请

US20130035747A1 METHODS FOR TREATING AIRWAYS 审中-公开
标题翻译：方法处理航空
公开(公告)号：US20130035747A1
公开(公告)日：2013-02-07
申请号：US13557518
申请日：2012-07-25
申请人： Christopher J. DANEK , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly M. Shriner , William J. Wizeman
发明人： Christopher J. DANEK , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly M. Shriner , William J. Wizeman
IPC分类号： A61F7/12
CPC分类号： A61B1/00085 , A61B5/053 , A61B5/0538 , A61B5/08 , A61B5/0809 , A61B5/1076 , A61B5/411 , A61B5/4519 , A61B5/4836 , A61B5/4878 , A61B5/6853 , A61B5/6858 , A61B10/04 , A61B18/06 , A61B18/14 , A61B18/1492 , A61B18/18 , A61B2010/045 , A61B2017/00106 , A61B2017/00809 , A61B2018/00214 , A61B2018/00541 , A61B2018/00773 , A61B2018/00875 , A61B2018/00898 , A61B2018/1472 , A61B2090/061 , A61B2090/064 , A61N5/1001
摘要： This relates to treating airways in a lung to decrease asthmatic symptoms. The also includes steps of measuring a parameter of an airway at a plurality of locations in a lung, identifying at least one treatment site from at least one of the plurality of locations based on the parameter, and applying energy to the treatment site to reduce the ability of the site to narrow.
摘要翻译：这涉及治疗肺中的气道以减少哮喘症状。还包括测量肺中多个位置处的气道参数的步骤，基于参数从多个位置中的至少一个位置识别至少一个治疗部位，并将能量施加到治疗部位以减少网站的能力缩小。

32. 发明授权

US08057470B2 Integrated smoke evacuation electrosurgical pencil and method 有权
标题翻译：综合排烟电手术铅笔和方法
公开(公告)号：US08057470B2
公开(公告)日：2011-11-15
申请号：US11897457
申请日：2007-08-30
申请人： Alan R. Lee , Michael Biggs
发明人： Alan R. Lee , Michael Biggs
IPC分类号： A61B18/14
CPC分类号： A61B18/1402 , A61B2018/1495 , A61B2218/008
摘要： An electrosurgical pencil includes an adjustable-length suction tube which surrounds a stationary electrode to evacuate smoke and electrosurgical byproducts from a surgical site. An electrode anchor unit is located within the interior of the suction tube to allow relative movement of the suction tube relative to a stationarily-retained electrode, and to receive and connect to different lengths of the electrodes. Adjusting the length of the suction tube relative to the different lengths of the electrode achieves effective evacuation, among other things.
摘要翻译：电外科手术铅笔包括可调节长度的吸入管，其围绕固定电极以从外科手术部位排出烟雾和电外科副产物。电极锚固单元位于吸入管的内部，以允许吸管相对于静止保持电极的相对运动，并且接收和连接到不同长度的电极。相对于电极的不同长度调节吸管的长度，除其他外，还能实现有效的抽气。

33. 发明授权

US07854734B2 Control system and process for application of energy to airway walls and other mediums 有权
标题翻译：控制系统和能量应用于气道壁和其他介质的过程
公开(公告)号：US07854734B2
公开(公告)日：2010-12-21
申请号：US11458074
申请日：2006-07-17
申请人： Michael Biggs , Roger A. Stern , Christopher J. Danek
发明人： Michael Biggs , Roger A. Stern , Christopher J. Danek
IPC分类号： A61B18/14 , A61B18/10
CPC分类号： A61N1/06 , A61B18/14 , A61B2018/00541 , A61N1/40
摘要： The present invention includes a system for delivering energy to an airway wall of a lung comprising an energy delivering apparatus and a PID controller having one or more variable gain factors which are rest after energy deliver has begun. The energy delivering apparatus may include a flexible elongated member and a distal expandable basket having at least one electrode for transferring energy to the airway wall and at least one temperature sensor for measuring temperature. The PID controller determines a new power set point base on an error between a preset temperature and the measured temperature. The algorithm can be Pi+1=Pi+G(αei+βei−1+γei−2) where α, β and γ are preset values and α is from 1 to 2; β is from −1 to −2; and γ is from −0.5 to 0-5. In another variation, the controller is configured to shut down if various measured parameters are exceeded such as, for example, energy, impedance, temperature, temperature differences, activation time and combinations thereof. Methods for treating a target medium using a PID algorithm are also provided.
摘要翻译：本发明包括一种用于向肺气道壁输送能量的系统，包括能量输送装置和具有一个或多个可变增益因子的PID控制器，所述可变增益因子在能量传递开始之后休息。能量输送装置可以包括柔性细长构件和远端可膨胀篮，其具有用于将能量传递到气道壁的至少一个电极和用于测量温度的至少一个温度传感器。 PID控制器根据预设温度和测量温度之间的误差确定新的功率设定点。该算法可以是Pi + 1 = Pi + G（αei+＆bgr; ei-1 +γei-2）其中α，＆bgr; γ为预设值，α为1〜2; ＆bgr 从-1到-2; γ为-0.5〜0-5。在另一变型中，控制器被配置为如果超过各种测量参数，例如能量，阻抗，温度，温差，激活时间及其组合，则关闭。还提供了使用PID算法处理目标介质的方法。

34. 发明申请

US20070101802A1 System and process for break detection in porous elements for screening or filtering 有权
标题翻译：用于筛选或过滤的多孔元件中的断裂检测的系统和过程
公开(公告)号：US20070101802A1
公开(公告)日：2007-05-10
申请号：US11270050
申请日：2005-11-08
申请人： Michael Biggs
发明人： Michael Biggs
IPC分类号： G01N15/08
CPC分类号： G01N15/08 , G01N9/24 , G01N22/02 , G01N2015/084
摘要： A method of detecting breaks in a porous element in a material separator is disclosed. A shielding is created in the material separator to form a barrier to RF energy. The shielding is formed with a path through the barrier capable of allowing RF energy and material to flow therethrough. The electrically conductive porous element is positioned fully across the path. An RF signal is transmitted on one side of the porous element, and signal levels of the RF signal are detected on the other side of the porous element, such that the detected RF signal crosses the porous element. A baseline signal strength indicator is established from the detected signal levels using an unbroken porous element. An operative signal strength indicator is generated from the detected signal levels. Breaks in the porous element are detected by comparing the operative signal strength indicator against the baseline signal strength indicator.
摘要翻译：公开了一种检测材料分离器中多孔元件断裂的方法。在材料分离器中产生屏蔽以形成对RF能量的屏障。屏蔽形成有通过阻挡物的路径，其能够使RF能量和材料流过其中。导电多孔元件完全穿过路径。 RF信号在多孔元件的一侧上传输，并且在多孔元件的另一侧检测RF信号的信号电平，使得检测到的RF信号与多孔元件交叉。使用不间断的多孔元件从检测到的信号电平建立基线信号强度指示符。从检测到的信号电平产生操作信号强度指示符。通过将操作信号强度指示符与基线信号强度指示器进行比较来检测多孔元件中的断裂。

35. 发明授权

US07104987B2 Control system and process for application of energy to airway walls and other mediums 有权
标题翻译：控制系统和能量应用于气道壁和其他介质的过程
公开(公告)号：US07104987B2
公开(公告)日：2006-09-12
申请号：US10414411
申请日：2003-04-14
申请人： Michael Biggs , Roger A. Stern , Christopher James Danek
发明人： Michael Biggs , Roger A. Stern , Christopher James Danek
IPC分类号： A61B18/18
CPC分类号： A61N1/06 , A61B18/14 , A61B2018/00541 , A61N1/40
摘要： The present invention includes a system for delivering energy to an airway wall of a lung comprising an energy delivering apparatus and a PID controller having one or more variable gain factors which are rest after energy deliver has begun. The energy delivering apparatus may include a flexible elongated member and a distal expandable basket having at least one electrode for transferring energy to the airway wall and at least one temperature sensor for measuring temperature. The PID controller determines a new power set point base on an error between a preset temperature and the measured temperature. The algorithm can be Pi+1=Pi+G(αei+βei−1+γei−2) where α, β and γ are preset values and α is from 1 to 2; βis from −1 to −2; and γ is from −0.5 to 0−5. In another variation, the controller is configured to shut down if various measured parameters are exceeded such as, for example, energy, impedance, temperature, temperature differences, activation time and combinations thereof. Methods for treating a target medium using a PID algorithm are also provided.
摘要翻译：本发明包括一种用于向肺气道壁输送能量的系统，包括能量输送装置和具有一个或多个可变增益因子的PID控制器，所述可变增益因子在能量传递开始之后休息。能量输送装置可以包括柔性细长构件和远端可膨胀篮，其具有用于将能量传递到气道壁的至少一个电极和用于测量温度的至少一个温度传感器。 PID控制器根据预设温度和测量温度之间的误差确定新的功率设定点。该算法可以是P + 1 + 1 + 1 + 1 + 1 + 其中α，β和γ是预设值，α是1至2; 贝塔从-1到-2; 而γ为-0.5至0-5。在另一变型中，控制器被配置为如果超过各种测量参数，例如能量，阻抗，温度，温差，激活时间及其组合，则关闭。还提供了使用PID算法处理目标介质的方法。

36. 发明授权

US08888769B2 Control system and process for application of energy to airway walls and other mediums 有权
标题翻译：控制系统和能量应用于气道壁和其他介质的过程
公开(公告)号：US08888769B2
公开(公告)日：2014-11-18
申请号：US12944238
申请日：2010-11-11
申请人： Michael Biggs , Roger A. Stern , Christopher J. Danek
发明人： Michael Biggs , Roger A. Stern , Christopher J. Danek
IPC分类号： A61B18/10 , A61N1/06 , A61N1/40 , A61B18/00
CPC分类号： A61N1/06 , A61B18/14 , A61B2018/00541 , A61N1/40
摘要： The present invention includes a system for delivering energy to an airway wall of a lung comprising an energy delivering apparatus and a PID controller having one or more variable gain factors which are rest after energy deliver has begun. The energy delivering apparatus may include a flexible elongated member and a distal expandable basket having at least one electrode for transferring energy to the airway wall and at least one temperature sensor for measuring temperature. The PID controller determines a new power set point base on an error between a preset temperature and the measured temperature. The algorithm can be Pi+1=Pi+G(αei+βei−1+γei−2) where α, β and γ are preset values and α is from 1 to 2; β is from −1 to −2; and γ is from −0.5 to 0.5. In another variation, the controller is configured to shut down if various measured parameters are exceeded such as, for example, energy, impedance, temperature, temperature differences, activation time and combinations thereof. Methods for treating a target medium using a PID algorithm are also provided.
摘要翻译：本发明包括一种用于向肺气道壁输送能量的系统，包括能量输送装置和具有一个或多个可变增益因子的PID控制器，所述可变增益因子在能量传递开始之后休息。能量输送装置可以包括柔性细长构件和远端可膨胀篮，其具有用于将能量传递到气道壁的至少一个电极和用于测量温度的至少一个温度传感器。 PID控制器根据预设温度和测量温度之间的误差确定新的功率设定点。该算法可以是Pi + 1 = Pi + G（αei+＆bgr; ei-1 +γei-2）其中α，＆bgr; γ为预设值，α为1〜2; ＆bgr 从-1到-2; γ为-0.5〜0.5。在另一变型中，控制器被配置为如果超过各种测量参数，例如能量，阻抗，温度，温差，激活时间及其组合，则关闭。还提供了使用PID算法处理目标介质的方法。

37. 发明授权

US08251070B2 Methods for treating airways 有权
标题翻译：治疗气道的方法
公开(公告)号：US08251070B2
公开(公告)日：2012-08-28
申请号：US11398353
申请日：2006-04-04
申请人： Christopher J. Danek , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly M. Shriner , William J. Wizeman
发明人： Christopher J. Danek , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly M. Shriner , William J. Wizeman
IPC分类号： A61B19/00 , A61B18/18 , A61F7/00 , A61F7/12
CPC分类号： A61B18/14 , A61B1/00085 , A61B5/053 , A61B5/0538 , A61B5/08 , A61B5/0809 , A61B5/1076 , A61B5/411 , A61B5/4519 , A61B5/4836 , A61B5/4878 , A61B5/6853 , A61B5/6858 , A61B10/04 , A61B18/06 , A61B18/1492 , A61B18/18 , A61B2010/045 , A61B2017/00106 , A61B2017/00809 , A61B2018/00214 , A61B2018/00541 , A61B2018/00773 , A61B2018/00875 , A61B2018/00898 , A61B2018/1472 , A61B2090/061 , A61B2090/064 , A61N5/1001
摘要： This relates to a method of treating airways in a lung to decrease asthmatic symptoms. The method also includes steps of measuring a parameter of an airway at a plurality of locations in a lung, identifying at least one treatment site from at least one of the plurality of locations based on the parameter, and applying energy to the treatment site to reduce the ability of the site to narrow.
摘要翻译：这涉及一种治疗肺部气道以减少哮喘症状的方法。该方法还包括以下步骤：测量肺中多个位置处的气道参数，基于该参数从至少一个位置识别至少一个治疗部位，并将能量施加到治疗部位以减少网站的能力缩小。

38. 发明授权

US08464723B2 Methods of evaluating individuals having reversible obstructive pulmonary disease 有权
标题翻译：评估具有可逆性阻塞性肺疾病的个体的方法
公开(公告)号：US08464723B2
公开(公告)日：2013-06-18
申请号：US13171345
申请日：2011-06-28
申请人： Christopher J. Danek , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly Shriner , William J. Wizeman
发明人： Christopher J. Danek , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly Shriner , William J. Wizeman
IPC分类号： A61B19/00 , A61B5/00 , A61B18/18 , A61F7/00 , A61F7/12
CPC分类号： A61B18/00 , A61B17/22004 , A61B18/08 , A61B18/14 , A61B18/1492 , A61B2017/00115 , A61B2017/00292 , A61B2017/003 , A61B2017/22062 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/044 , A61B2018/046 , A61B2018/1807 , A61B2090/3614 , A61M25/0043 , A61M29/00 , A61M2025/0096 , A61M2210/1039 , A61N5/0601
摘要： This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.
摘要翻译：这涉及治疗哮喘肺，更具体地涉及将治疗装置推进到肺中并用装置治疗肺。这还包括治疗气道壁，向哮喘肺中的气道壁施加能量或热量的附加步骤。

39. 发明授权

US08181656B2 Methods for treating airways 有权
标题翻译：治疗气道的方法
公开(公告)号：US08181656B2
公开(公告)日：2012-05-22
申请号：US11361564
申请日：2006-02-23
申请人： Christopher J. Danek , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly M. Shriner
发明人： Christopher J. Danek , Michael Biggs , Bryan E. Loomas , Michael D. Laufer , Gary S. Kaplan , Kelly M. Shriner
IPC分类号： A61B19/00
CPC分类号： A61B17/24 , A61B17/22004 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/1492 , A61B18/18 , A61B2017/00115 , A61B2017/00292 , A61B2017/003 , A61B2017/22062 , A61B2017/242 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/044 , A61B2018/046 , A61B2018/1807 , A61B2090/3614 , A61M25/0043 , A61M29/00 , A61M2025/0096 , A61M2210/1039 , A61N1/3601 , A61N5/0601
摘要： This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.
摘要翻译：这涉及治疗哮喘肺，更具体地涉及将治疗装置推进到肺中并用装置治疗肺。这还包括治疗气道壁，向哮喘肺中的气道壁施加能量或热量的附加步骤。

40. 发明授权

US07837679B2 Control system and process for application of energy to airway walls and other mediums 有权
公开(公告)号：US07837679B2
公开(公告)日：2010-11-23
申请号：US11458084
申请日：2006-07-17
申请人： Michael Biggs , Roger A. Stern , Christopher J. Danek
发明人： Michael Biggs , Roger A. Stern , Christopher J. Danek
IPC分类号： A61B18/10
CPC分类号： A61N1/06 , A61B18/14 , A61B2018/00541 , A61N1/40
摘要： The present invention includes a system for delivering energy to an airway wall of a lung comprising an energy delivering apparatus and a PID controller having one or more variable gain factors which are rest after energy deliver has begun. The energy delivering apparatus may include a flexible elongated member and a distal expandable basket having at least one electrode for transferring energy to the airway wall and at least one temperature sensor for measuring temperature. The PID controller determines a new power set point base on an error between a preset temperature and the measured temperature. The algorithm can be Pi+1=Pi+G(αei+βei−1+γei−2) where α, β and γ are preset values and α is from 1 to 2; β is from −1 to −2; and γ is from −0.5 to 0-5. In another variation, the controller is configured to shut down if various measured parameters are exceeded such as, for example, energy, impedance, temperature, temperature differences, activation time and combinations thereof. Methods for treating a target medium using a PID algorithm are also provided.

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