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31. 发明授权

US08043867B2 Assay test strips and reading same 有权
标题翻译：测试条和阅读相同
公开(公告)号：US08043867B2
公开(公告)日：2011-10-25
申请号：US12409871
申请日：2009-03-24
申请人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
发明人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
IPC分类号： G01N33/53
CPC分类号： G01N33/54386 , G01N21/17 , G01N21/274 , G01N21/6428 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2201/062 , G01N2201/067 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/809 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要： An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.
摘要翻译：测定试片包括流路，样品接收区，标签，包括感兴趣区域的检测区和至少一个位置标记。所述至少一个位置标记相对于所述感兴趣区域对齐，使得所述至少一个位置标记的位置指示所述感兴趣区域的位置。诊断测试系统包括从测试条的暴露区域获得光强度测量的读取器，以及数据分析器，其执行以下至少一个：（a）基于至少一个（a）识别从测试区域获得的光强度测量中的一个测量从所述至少一个参考特征获得的，以及（b）基于从所述至少一个参考特征获得的至少一个测量值生成修改所述读取器的至少一个操作参数的控制信号。

32. 发明申请

US20100195935A1 SYSTEM AND METHOD FOR PERFORMING OPTICAL NAVIGATION USING ENHANCED FRAMES OF IMAGE DATA 有权
标题翻译：使用图像数据的增强框架执行光学导航的系统和方法
公开(公告)号：US20100195935A1
公开(公告)日：2010-08-05
申请号：US12362663
申请日：2009-01-30
申请人： Michael J. Brosnan
发明人： Michael J. Brosnan
IPC分类号： G06K7/10
CPC分类号： G06F3/0317
摘要： A system and method for performing optical navigation uses a spatial noise pattern estimate of the spatial noise pattern in captured frames of image data caused by contamination on at least one component of the system to substantially remove the spatial noise pattern in the captured frames of image data before the captured frames of image data are used for displacement estimation.
摘要翻译：用于执行光学导航的系统和方法使用由所述系统的至少一个分量的污染引起的图像数据的捕获帧中的空间噪声模式的空间噪声模式估计，以基本上去除所捕获的图像数据帧中的空间噪声模式在拍摄的图像数据帧用于位移估计之前。

33. 发明申请

US20090180929A1 ASSAY TEST STRIPS WITH MULTIPLE LABELS AND READING SAME 审中-公开
公开(公告)号：US20090180929A1
公开(公告)日：2009-07-16
申请号：US12410182
申请日：2009-03-24
申请人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman
发明人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman
IPC分类号： G01N21/00
CPC分类号： G01N33/558 , G01N33/582 , G01N2021/7786 , G01N2035/00108
摘要： In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.

34. 发明申请

US20090180926A1 ASSAY TEST STRIPS AND READING SAME 有权
公开(公告)号：US20090180926A1
公开(公告)日：2009-07-16
申请号：US12409871
申请日：2009-03-24
申请人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
发明人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman , Bo U. Curry
IPC分类号： G01N31/22
CPC分类号： G01N33/54386 , G01N21/17 , G01N21/274 , G01N21/6428 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2201/062 , G01N2201/067 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/809 , Y10S436/81 , Y10S436/823 , Y10T436/25125
摘要： An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.

35. 发明授权

US07521259B2 Assay test strips with multiple labels and reading same 有权
标题翻译：测试带有多个标签并读取相同的测试条
公开(公告)号：US07521259B2
公开(公告)日：2009-04-21
申请号：US11236152
申请日：2005-09-26
申请人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman
发明人： Patrick T. Petruno , John F. Petrilla , Michael J. Brosnan , Rong Zhou , Daniel B. Roitman
IPC分类号： G01N33/53
CPC分类号： G01N21/8483 , G01N33/558 , G01N2021/6441 , Y10S435/805 , Y10S435/823 , Y10S436/807 , Y10S436/823 , Y10T436/25125
摘要： In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.
摘要翻译：在一个方面，分析测试条包括特异性结合目标分析物的测试标签和对目标分析物没有任何特异性结合亲和力并且具有与测试标记不同的光学特性的对照标记。在另一方面，测定试片包括特异性结合目标分析物和至少一种对目标分析物没有任何特异性结合亲和力的非特异性结合标记的测试标记。还描述了读取测定条带的系统和方法。

36. 发明申请

US20080283847A1 Integrated circuit package provided with cooperatively arranged illumination and sensing capabilities 有权
标题翻译：集成电路封装提供协调布置的照明和感测功能
公开(公告)号：US20080283847A1
公开(公告)日：2008-11-20
申请号：US11591955
申请日：2006-11-01
申请人： Vincent C. Moyer , Michael J. Brosnan
发明人： Vincent C. Moyer , Michael J. Brosnan
IPC分类号： H01L31/12 , H01L21/50
CPC分类号： G06F3/03543 , G06F3/0421 , H01L2224/48091 , H01L2224/49171 , H01L2924/00014
摘要： An integrated circuit package includes an angled one-piece substrate having a light source fixed to one area and a sensor die fixed to a second area, such that the light source is directed to illuminate the field of view of the sensor die when a surface of interest is imaged. The integrated circuit package is well suited for generating navigation information regarding movement relative to a surface. In one method of forming the integrated circuit package, the single-piece substrate is originally a generally flat lead frame to which the sensor die and light source are attached. After the components have been connected, the lead frame is bent to provide the desired light source-to-sensor angle. In an alternative method, the lead frame is pre-bent. For either method, optics may be connected to the integrated circuit package, thereby providing a module that includes the optics, the light source, the sensor and the packaging body.
摘要翻译：集成电路封装包括具有固定到一个区域的光源的角度一体式衬底和固定到第二区域上的传感器管芯，使得当光源被引导以照射传感器管芯的视场时兴趣成像。集成电路封装非常适合于产生关于相对于表面移动的导航信息。在形成集成电路封装的一种方法中，单片式衬底最初是连接有传感器裸片和光源的大致扁平的引线框架。在组件已经连接之后，引线框架被弯曲以提供期望的光源到传感器的角度。在另一种方法中，引线框架是预弯曲的。对于任一方法，光学器件可以连接到集成电路封装，从而提供包括光学器件，光源，传感器和封装体的模块。

37. 发明授权

US07446756B2 Apparatus for controlling the position of a screen pointer with low sensitivity to particle contamination 有权
标题翻译：用于控制对微粒污染的低灵敏度的屏幕指针的位置的装置
公开(公告)号：US07446756B2
公开(公告)日：2008-11-04
申请号：US10805814
申请日：2004-03-22
申请人： Michael J. Brosnan , Ramakrishna Kakarala , Roopinder Singh Grewal , Mark M. Butterworth , Vincent C. Moyer , Tong Xie , Marshall T. Depue
发明人： Michael J. Brosnan , Ramakrishna Kakarala , Roopinder Singh Grewal , Mark M. Butterworth , Vincent C. Moyer , Tong Xie , Marshall T. Depue
IPC分类号： G09G5/08 , G01P3/36
CPC分类号： G01M11/00 , G06F3/0317
摘要： An apparatus for controlling the position of a screen pointer includes an at least partially coherent light source for illuminating an imaging surface, thereby generating reflected images. The apparatus includes a navigation sensor for generating digital images based on the reflected images, performing a movement computation based on the digital images, generating movement data based on the movement computation that is indicative of relative motion between the imaging surface and the apparatus, wherein the movement computation has a low sensitivity to effects in the digital images caused by particle contamination.
摘要翻译：用于控制屏幕指针的位置的装置包括用于照射成像表面的至少部分相干的光源，从而产生反射的图像。该装置包括：导航传感器，用于基于反射图像生成数字图像，基于数字图像执行移动计算;基于指示成像表面和装置之间的相对运动的运动计算产生移动数据;其中，运动计算对由颗粒污染引起的数字图像的影响具有低的灵敏度。

38. 发明申请

US20080030586A1 Optical motion sensing 有权
标题翻译：光学运动感应
公开(公告)号：US20080030586A1
公开(公告)日：2008-02-07
申请号：US11500077
申请日：2006-08-07
申请人： Rene Helbing , Todd Sachs , Michael J. Brosnan
发明人： Rene Helbing , Todd Sachs , Michael J. Brosnan
IPC分类号： H04N5/228
CPC分类号： H04N5/23248 , G06T7/20 , H04N5/23258 , H04N5/23267 , H04N5/3415 , H04N21/41407 , H04N2007/145
摘要： Optical motion sensing systems and methods are described. In one aspect, light from subfields of a scene is focused onto respective capture areas of a focal plane. Successive sets of contemporaneous local images are captured from the focused light. Respective saliency measures are derived from respective ones of the local images. Respective local motion measures are determined from comparisons of corresponding ones of the local images in ones of the contemporaneous local image sets. A respective global motion measure is produced for each of the contemporaneous local image sets based on the respective ones of the local motion measures and the respective ones of the saliency measures.
摘要翻译：描述了光学运动感测系统和方法。在一个方面，来自场景的子场的光聚焦到焦平面的相应捕获区域上。从集中的光线捕获了同时期的当地图像的连续集。相应的显着性度量来自相应的本地图像。通过本地图像中相应的局部图像的比较来确定相应的局部运动度量。基于本地运动测量和相应的显着度量度中的相应的本地运动测量，针对每个同期的局部图像组产生相应的全局运动测量。

39. 发明授权

US07295186B2 Apparatus for controlling a screen pointer that distinguishes between ambient light and light from its light source 有权
标题翻译：用于控制屏幕指针的装置，其区分环境光和来自其光源的光
公开(公告)号：US07295186B2
公开(公告)日：2007-11-13
申请号：US10341710
申请日：2003-01-14
申请人： Michael J. Brosnan
发明人： Michael J. Brosnan
IPC分类号： G09G5/08
CPC分类号： G06F3/0317
摘要： An apparatus for controlling the position of a screen pointer for an electronic device having a display screen, includes a light source for illuminating an imaging surface with a plurality of light pulses, thereby generating reflected light pulses. A detection circuit is configured to sense light, distinguish between the reflected pulses and ambient light, and generate a low signal indication if the magnitude of the reflected pulses falls below a threshold value. An optical motion sensor generates digital images based on the reflected pulses. The motion sensor is configured to generate movement data based on the digital images. The movement data is indicative of relative motion between the imaging surface and the apparatus.
摘要翻译：一种用于控制具有显示屏的电子设备的屏幕指针的位置的装置，包括用于利用多个光脉冲照射成像表面的光源，从而产生反射的光脉冲。检测电路被配置为感测光，区分反射脉冲和环境光，并且如果反射脉冲的幅度低于阈值，则产生低信号指示。光学运动传感器基于反射脉冲产生数字图像。运动传感器被配置为基于数字图像生成移动数据。运动数据表示成像表面和装置之间的相对运动。

40. 发明授权

US06995748B2 Apparatus for controlling a screen pointer with a frame rate based on velocity 有权
标题翻译：用于以基于速度的帧速率控制屏幕指针的装置
公开(公告)号：US06995748B2
公开(公告)日：2006-02-07
申请号：US10338257
申请日：2003-01-07
申请人： Gary B. Gordon , Michael J. Brosnan
发明人： Gary B. Gordon , Michael J. Brosnan
IPC分类号： G09G5/08
CPC分类号： G06F3/038 , G06F1/3203 , G06F1/3259 , G06F3/0317 , G06F3/03547 , G06F2203/0338 , G06T7/20 , Y02D10/155
摘要： An apparatus for controlling the position of a screen pointer for an electronic device having a display screen includes a light source for illuminating an imaging surface, thereby generating reflected images. An optical motion sensor generates digital images from the reflected images at a first frame rate. The motion sensor is configured to generate movement data based on the digital images. The movement data is indicative of relative motion between the imaging surface and the apparatus. The motion sensor is configured to modify the first frame rate to one of a plurality of alternate frame rates based on a current relative velocity between the imaging surface and the apparatus.
摘要翻译：用于控制具有显示屏的电子设备的屏幕指针的位置的装置包括用于照射成像表面的光源，从而产生反射的图像。光学运动传感器以第一帧速率从反射图像生成数字图像。运动传感器被配置为基于数字图像生成移动数据。运动数据表示成像表面和装置之间的相对运动。运动传感器被配置为基于成像表面和装置之间的当前相对速度将第一帧速率修改为多个替代帧频之一。

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