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31. 发明授权

US08642712B2 Actinically-crosslinkable siloxane-containing copolymers 有权
标题翻译：光滑交联的含硅氧烷共聚物
公开(公告)号：US08642712B2
公开(公告)日：2014-02-04
申请号：US12783592
申请日：2010-05-20
申请人： Frank Chang , Jinyu Huang , Robert Scott , Guigui Wang
发明人： Frank Chang , Jinyu Huang , Robert Scott , Guigui Wang
IPC分类号： C08F30/08
CPC分类号： A61K47/32 , B29D11/00038 , C08F8/14 , C08F8/26 , C08F230/08 , C08F283/12 , C08F290/068 , C08F291/04 , C08F293/005 , C08F299/08 , C08F2438/01 , C08F2810/30 , C08F2810/40 , C08G77/14 , C08G77/26 , C08G77/385 , C08G77/392 , C08J3/075 , C08J2300/14 , C08J2383/06 , C08J2383/07 , C08J2383/08 , C08L53/00 , G02B1/043 , G02C7/04 , C08F220/56 , C08F226/10 , C08F220/28 , C08L101/14 , C08L83/04 , C08F220/20
摘要： The invention provide a class of actinically-crosslinkable silicone-containing prepolymers obtained by functionalizing an intermediary copolymer to have two or more thiol or ethylenically-unsaturated groups covalently attached thereto, wherein the intermediary copolymer is an atom-transfer radical polymerization (ATRP) product of a reactive mixture comprising a polysiloxane ATRP macroinitiator and at least one hydrophilic vinylic monomer. The present invention is also related to silicone hydrogel contact lenses made from a prepolymer of the invention and methods for making the contact lenses in a cost-effective way and with high consistency and high fidelity to the original lens design.
摘要翻译：本发明提供一类通过官能化中间共聚物获得的具有两个或更多个共价连接到其上的硫醇或烯键式不饱和基团获得的含有机硅的预聚物，其中中间共聚物是原子转移自由基聚合（ATRP）包含聚硅氧烷ATRP大分子引发剂和至少一种亲水性乙烯基单体的反应性混合物。本发明还涉及由本发明的预聚物制成的硅酮水凝胶隐形眼镜以及以成本有效的方式制造隐形眼镜并以与原始透镜设计的高一致性和高保真度的方法。

32. 发明申请

US20120088861A1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF 有权
标题翻译：含水硅氧烷的预处理剂及其用途
公开(公告)号：US20120088861A1
公开(公告)日：2012-04-12
申请号：US13253186
申请日：2011-10-05
申请人： Jinyu Huang , Frank Chang , Robert Scott , Arturo Norberto Medina , Manivakkam J. Shankernarayanan , Selma Kuyu , Dawn Alison Smith , Daqing Wu
发明人： Jinyu Huang , Frank Chang , Robert Scott , Arturo Norberto Medina , Manivakkam J. Shankernarayanan , Selma Kuyu , Dawn Alison Smith , Daqing Wu
IPC分类号： G02C7/04 , C08F230/08 , B29D11/00 , C08F290/06
CPC分类号： G02B1/043 , C08G77/20 , C08G77/42 , C08G77/442 , C08J3/075 , C08J2343/04 , C08J2383/08 , C08L83/10 , C08L101/14 , C08L83/04
摘要： The invention provide a class of water-processable polymerizable prepolymers which comprises (1) siloxane-containing monomeric units derived at least one siloxane containing monomer having one hydrophilic group or chain and/or polysiloxane-containing crosslinking units derived from at least one hydrophilized polysiloxane or chain-extended polysiloxane crosslinker; (2) hydrophilic monomeric units derived from one or more hydrophilic vinylic monomers; and (3) from about 0.05% to about 5% by weight of polymerizable units each having a pendant or terminal, ethylenically-unsaturated group and free of any polysiloxane segment. The prepolymer comprises from about 20% to about 50% by weight of silicone relative to the total weight of the prepolymer and has a high water solubility or dispersibility of at least about 5% by weight in water and suitable for making silicone hydrogel contact lenses.
摘要翻译：本发明提供了一类可水加工的可聚合预聚物，其包含（1）衍生自至少一种含有一个含硅氧烷的单体的含硅氧烷的单体单元，所述单体具有一个亲水基团或至少一种亲水化聚硅氧烷的链和/或含聚硅氧烷的交联单元，或链延长聚硅氧烷交联剂; （2）衍生自一种或多种亲水乙烯基单体的亲水单体单元; 和（3）约0.05％至约5％重量的各自具有侧基或末端的可聚合单元，烯属不饱和基团并且不含任何聚硅氧烷链段。预聚物相对于预聚物的总重量包含约20重量％至约50重量％的硅氧烷，并且在水中具有至少约5重量％的高水溶性或分散性，并且适于制备硅酮水凝胶隐形眼镜。

33. 发明申请

US20120029111A1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF 有权
标题翻译：聚硅氧烷聚合物预聚物及其用途
公开(公告)号：US20120029111A1
公开(公告)日：2012-02-02
申请号：US13193642
申请日：2011-07-29
申请人： Frank Chang , Robert Scott , Jinyu Huang , Arturo N. Medina , Dawn A. Smith , Laura Ann Sanders , John Dallas Pruitt
发明人： Frank Chang , Robert Scott , Jinyu Huang , Arturo N. Medina , Dawn A. Smith , Laura Ann Sanders , John Dallas Pruitt
IPC分类号： G02C7/04 , B29D11/00 , G02B1/12 , C07F7/10
CPC分类号： G02B1/043 , C08F290/068 , C08G77/388 , C08G77/458 , C08G2210/00 , C08L2205/02 , C08L83/04 , C08L51/085 , C08L101/14 , C08F220/56 , C08F220/28
摘要： The present invention provides an amphiphilic polysiloxane prepolymer which comprises hydrophilic monomeric units derived from at least one hydrophilic vinylic monomer, polysiloxane crosslinking units derived from at least one polysiloxane crosslinker having at least two terminal ethylenically-unsaturated groups, dangling polysiloxane chains each of which is terminated with one ethylenically unsaturated group, and chain-transfer units derived from a chain transfer agent other than a RAFT agent. A prepolymer of the invention is suitable for making hydrogel contact lenses. The present invention is also related to hydrogel contact lenses made from an amphiphilic polysiloxane prepolymer of the invention and to processes for preparing an amphiphilic polysiloxane prepolymer of the invention and for making silicone hydrogel contact lenses.
摘要翻译：本发明提供一种两亲性聚硅氧烷预聚物，其包含衍生自至少一种亲水乙烯基单体的亲水性单体单元，衍生自至少一种具有至少两个末端烯属不饱和基团的聚硅氧烷交联剂的聚硅氧烷交联单元，悬浮聚硅氧烷链各自被终止具有一个烯键式不饱和基团，以及衍生自除RAFT试剂之外的链转移剂的链转移单元。本发明的预聚物适用于制备水凝胶隐形眼镜。本发明还涉及由本发明的两亲聚硅氧烷预聚物制成的水凝胶隐形眼镜以及制备本发明的两亲性聚硅氧烷预聚物和制备硅酮水凝胶隐形眼镜的方法。

34. 发明申请

US20100298446A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS 有权
标题翻译：具有交联性的含硅氧烷共聚物
公开(公告)号：US20100298446A1
公开(公告)日：2010-11-25
申请号：US12783592
申请日：2010-05-20
申请人： Frank Chang , Jinyu Huang , Robert Scott , Guigui Wang
发明人： Frank Chang , Jinyu Huang , Robert Scott , Guigui Wang
IPC分类号： A61K47/32 , C07F7/02 , C08F230/08 , C08L83/04 , G02C7/04 , A61P27/02
CPC分类号： A61K47/32 , B29D11/00038 , C08F8/14 , C08F8/26 , C08F230/08 , C08F283/12 , C08F290/068 , C08F291/04 , C08F293/005 , C08F299/08 , C08F2438/01 , C08F2810/30 , C08F2810/40 , C08G77/14 , C08G77/26 , C08G77/385 , C08G77/392 , C08J3/075 , C08J2300/14 , C08J2383/06 , C08J2383/07 , C08J2383/08 , C08L53/00 , G02B1/043 , G02C7/04 , C08F220/56 , C08F226/10 , C08F220/28 , C08L101/14 , C08L83/04 , C08F220/20
摘要： The invention provide a class of actinically-crosslinkable silicone-containing prepolymers obtained by functionalizing an intermediary copolymer to have two or more thiol or ethylenically-unsaturated groups covalently attached thereto, wherein the intermediary copolymer is an atom-transfer radical polymerization (ATRP) product of a reactive mixture comprising a polysiloxane ATRP macroinitiator and at least one hydrophilic vinylic monomer. The present invention is also related to silicone hydrogel contact lenses made from a prepolymer of the invention and methods for making the contact lenses in a cost-effective way and with high consistency and high fidelity to the original lens design.
摘要翻译：本发明提供一类通过官能化中间共聚物获得的具有两个或更多个共价连接到其上的硫醇或烯键式不饱和基团获得的含有机硅的预聚物，其中中间共聚物是原子转移自由基聚合（ATRP）包含聚硅氧烷ATRP大分子引发剂和至少一种亲水性乙烯基单体的反应性混合物。本发明还涉及由本发明的预聚物制成的硅酮水凝胶隐形眼镜以及以成本有效的方式制造隐形眼镜并以与原始透镜设计的高一致性和高保真度的方法。

35. 发明授权

US07710714B2 Housing for scale or load cell controller 有权
标题翻译：秤或外壳称重传感器控制器
公开(公告)号：US07710714B2
公开(公告)日：2010-05-04
申请号：US10939693
申请日：2004-09-13
申请人： Geoffrey D. Rapp , Robert Scott , Richard P. Bozzi , Dennis R. Seguin, Jr.
发明人： Geoffrey D. Rapp , Robert Scott , Richard P. Bozzi , Dennis R. Seguin, Jr.
IPC分类号： H05K5/00 , G01G19/22 , G01G23/18 , H01H9/04 , F16B35/02 , G09G5/00 , G06F3/041
CPC分类号： H05K5/0204 , G01G21/283 , H05K5/061
摘要： A housing for a scale or load cell controller suitable for use in harsh environments. The housing includes a moisture-resistant front display unit coupled to a rear interface and mounting unit. The front display unit includes a front housing, a back housing, and a frame overlying a boundary or seal region between the front and back housings to provide a double moisture-resistant seal between the front and back housings. The front display unit defines an interior region including a display and a plurality of user input keys and controller circuitry. The front display unit is removably attachable to the rear interface unit. A moisture-resistant seal is also provided between the front display unit and the rear interface and mounting unit. The rear interface and mounting unit defines a recessed area supporting a battery pack, a power supply and an interface circuit board. Circuitry in the front display unit is electrically coupled to circuitry in the rear interface and mounting unit via an edge connector circuit card that extends through an opening in the front display unit and mates with an edge connector socket supported in the rear interface and mounting unit.
摘要翻译：适用于恶劣环境的秤或称重传感器控制器的外壳。壳体包括耦合到后接口和安装单元的防潮前显示单元。前显示单元包括前壳体，后壳体和覆盖在前壳体和后壳体之间的边界或密封区域的框架，以在前壳体和后壳体之间提供双重防潮密封。前显示单元定义包括显示器和多个用户输入键和控制器电路的内部区域。前显示单元可拆卸地附接到后接口单元。在前显示单元和后接口和安装单元之间还提供防潮密封。后部接口和安装单元限定了支撑电池组，电源和接口电路板的凹陷区域。前显示单元中的电路通过延伸穿过前显示单元中的开口的边缘连接器电路卡电耦合到后接口和安装单元中的电路，并与支撑在后接口和安装单元中的边缘连接器插座配合。

36. 发明申请

US20090234270A1 Therapy and device for treatment of nail infections 审中-公开
标题翻译：治疗和治疗指甲感染的装置
公开(公告)号：US20090234270A1
公开(公告)日：2009-09-17
申请号：US12075393
申请日：2008-03-11
申请人： Nicholas G. Loebel , Fergus R. McKenzie , Cale Street , Roger Andersen , Robert Scott
发明人： Nicholas G. Loebel , Fergus R. McKenzie , Cale Street , Roger Andersen , Robert Scott
IPC分类号： A61N1/30
CPC分类号： A61K31/125 , A61B18/14 , A61B2018/00452 , A61B2018/00577 , A61K31/045 , A61N5/062 , A61N5/0624 , A61N2005/0645 , A61N2005/0652
摘要： The present invention includes a method for treating fungal infections, particularly onychomycosis. The method includes: applying a composition includes a photosensitizer, an effective amount of antifungal agent, and a pharmaceutically acceptable delivery system to a locus and irradiating the locus with a light source at a wavelength absorbed by the photosensitizer so as to destroy microbes at the locus. The present invention also includes a light delivery device for use in photodynamic treatment of onychomycosis comprising (i) a housing adapted to cover a nail beneath which a locus is situated; (ii) a light source; (iii) an energy source in power communication to the light source; and a controller that controls amount of light to be applied to the locus by the light source.
摘要翻译：本发明包括一种治疗真菌感染，特别是甲真菌病的方法。该方法包括：施用组合物包括光敏剂，有效量的抗真菌剂和药学上可接受的递送系统到一个场所，并用光敏元件吸收的波长的光源照射该场所，从而破坏该位点处的微生物。本发明还包括用于光动力治疗甲真菌病的光输送装置，其包括（i）适于覆盖位于其下的指甲的壳体; （ii）光源; （iii）与光源的电力通信中的能量源; 以及控制器，其控制由光源施加到轨迹的光量。

37. 发明申请

US20070213303A1 Methods for reducing platelet activation and for the treatment of thrombotic events 审中-公开
标题翻译：减少血小板活化和治疗血栓形成事件的方法
公开(公告)号：US20070213303A1
公开(公告)日：2007-09-13
申请号：US11544845
申请日：2006-10-06
申请人： Robert Scott , Victor Serebruany
发明人： Robert Scott , Victor Serebruany
IPC分类号： A61K31/66 , A61K31/277 , A61K31/185 , A61K31/192 , A61K31/18 , A61K31/165 , A61K31/138 , A61K31/10
CPC分类号： A61K31/661 , A61K31/10 , A61K31/138 , A61K31/165 , A61K31/18 , A61K31/185 , A61K31/192 , A61K31/277 , A61K31/66
摘要： Methods and compositions for the treatment or prophylaxis of a disorder associated with platelet activation or enhanced thrombin activity are provided, that include the administration of an effective amount of a compound of the formula: or its pharmaceutically acceptable salt, ester or prodrug, wherein the substituents are defined herein, optionally in the appropriate pharmaceutically acceptable carrier for the route of administration selected.
摘要翻译：提供了用于治疗或预防与血小板活化或增强的凝血酶活性相关的病症的方法和组合物，其包括施用有效量的下式化合物或其药学上可接受的盐，酯或前药，其中取代基在本文中定义，任选地在所选择的给药途径的适当的药学上可接受的载体中。

38. 发明申请

US20070087939A1 Biopolymer compositions and products thereof 审中-公开
标题翻译：生物聚合物组合物及其制品
公开(公告)号：US20070087939A1
公开(公告)日：2007-04-19
申请号：US11582016
申请日：2006-10-17
申请人： Dominique Cade , Marie Miralles , Robert Scott , Claire Tardy
发明人： Dominique Cade , Marie Miralles , Robert Scott , Claire Tardy
IPC分类号： A01N25/28 , C12P19/04 , A61K9/48 , A23G3/00
CPC分类号： C08L1/02 , A61K9/4816 , C08L1/00 , C08L1/08 , C08L1/10 , C08L1/12 , C08L1/14 , C08L1/16 , C08L1/18 , C08L1/20 , C08L1/22 , C08L1/24 , C08L1/26 , C08L1/28 , C08L1/282 , C08L1/284 , C08L1/286 , C08L1/288 , C08L1/30 , C08L1/32 , C08L3/00 , C08L3/02 , C08L3/04 , C08L3/06 , C08L3/08 , C08L3/10 , C08L3/12 , C08L3/14 , C08L3/16 , C08L3/18 , C08L3/20 , C08L5/00 , C08L5/02 , C08L5/12 , C08L2666/02 , C08L2666/26
摘要： This invention relates to biopolymer-based compositions and biopolymer-based formed bodies such as film, sheet, capsule, casing or coating-film or spray thereof. In another embodiment, the invention relates to a process for producing a biopolymer-based starting material and biopolymer-based formed bodies such as cited above, for the manufacture of pharmaceutical, veterinary, food for cosmetic products.
摘要翻译：本发明涉及基于生物聚合物的组合物和基于生物聚合物的成型体，例如膜，片，胶囊，套管或其包衣或喷雾。在另一个实施方案中，本发明涉及生产基于生物聚合物的原料和如上所述的基于生物聚合物的成型体的方法，用于制造药物，兽医，化妆品的食品。

39. 发明申请

US20060245187A1 Dental curing light with specially arranged LEDs 失效
标题翻译：牙科治疗灯具有专门布置的LED
公开(公告)号：US20060245187A1
公开(公告)日：2006-11-02
申请号：US11118147
申请日：2005-04-29
申请人： Robert Scott , Dee Jessop , Dan Fischer
发明人： Robert Scott , Dee Jessop , Dan Fischer
IPC分类号： F21V33/00 , F21V9/00
CPC分类号： A61C19/004 , H05K1/18 , H05K1/181 , H05K3/3415 , H05K2201/10106 , Y10S362/804
摘要： A dental curing light including an elongate wand having a proximal end and a distal end, a plurality of LEDs disposed at or near a distal end of the elongate wand and a printed circuit board for mounting the plurality of LEDs. The LEDs include a main through mount LED and a plurality of surface mount LEDs positioned around the main through mount LED. The main LED is through mounted relative to the printed circuit board such that the power connections of the main through mount LED are made through a hole or holes in the printed circuit board. The power connections of the main through mount LED are made on an opposite surface of the printed circuit board relative to the “top” surface to which the surface mount LEDs are mounted.
摘要翻译：一种牙科固化灯，包括具有近端和远端的细长棒，设置在细长棒的远端处或附近的多个LED以及用于安装多个LED的印刷电路板。 LED包括主通孔安装LED和围绕主通孔安装LED定位的多个表面安装LED。主LED通过相对于印刷电路板安装，使得主通过安装LED的电源连接通过印刷电路板中的孔或孔制成。主通孔安装LED的电源连接相对于安装表面安装LED的“顶”表面在印刷电路板的相对表面上制成。

40. 发明申请

US20060142974A1 Method and system for remotely processing volumetric data 有权
标题翻译：用于远程处理体积数据的方法和系统
公开(公告)号：US20060142974A1
公开(公告)日：2006-06-29
申请号：US11027382
申请日：2004-12-29
申请人： Robert Scott , Matthew Housey , L. Hazlewood , Kenneth Stephens
发明人： Robert Scott , Matthew Housey , L. Hazlewood , Kenneth Stephens
IPC分类号： G06F11/00
CPC分类号： G01F23/0038 , G01F23/0061 , G01F23/20
摘要： In accordance with an aspect of the present invention, a system for providing storage tank measurements to a remote location is provided. The system includes a control box configured to take a plurality of readings from within the storage tank and transmit those readings to a master computer. The master computer is configured to receive and store the plurality of readings, and in response to receiving a request for a measurement for the storage tank, calculate the requested measurement utilizing the received readings. The calculated measurements are then transmitted to the device requesting the measurements.
摘要翻译：根据本发明的一个方面，提供了一种用于向远程位置提供储罐测量的系统。该系统包括控制箱，该控制箱被配置为从存储箱内取出多个读数，并将这些读数传送到主计算机。主计算机被配置为接收和存储多个读数，并且响应于接收到对储存罐的测量的请求，使用所接收的读数来计算所请求的测量值。然后将所计算的测量值发送到请求测量的设备。

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