专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明申请

WO2009131911A2 MEDICAL DEVICES HAVING A COATING OF INORGANIC MATERIAL 审中-公开
标题翻译：具有无机材料涂层的医疗装置
公开(公告)号：WO2009131911A2
公开(公告)日：2009-10-29
申请号：PCT/US2009040964
申请日：2009-04-17
申请人： BOSTON SCIENT SCIMED INC , FLANAGAN AIDEN , KILCOOLEY JOHN , O'CONNOR TIM , O'BRIEN BARRY , SEIDEL DOMINIQUE , KUEHLING MICHAEL , SCHEUERMANN TORSTEN , WEBER JAN
发明人： FLANAGAN AIDEN , KILCOOLEY JOHN , O'CONNOR TIM , O'BRIEN BARRY , SEIDEL DOMINIQUE , KUEHLING MICHAEL , SCHEUERMANN TORSTEN , WEBER JAN
IPC分类号： A61L31/08 , A61L31/16
CPC分类号： A61L29/10 , A61L29/16 , A61L31/082 , A61L31/16 , A61L2300/602 , A61L2300/61
摘要： In one aspect, a medical device has a first configuration and a second configuration, a reservoir containing a therapeutic agent, and a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material. In another aspect, a medical device has a reservoir containing a therapeutic agent, a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material, and a swellable material disposed between the barrier layer and a surface of the medical device, wherein the swellable material is a material that swells upon exposure to an aqueous environment. In yet another aspect, a medical device has a multi-layered coating having alternating reservoir layers and barrier layers, and a plurality of excavated regions penetrating through at least a partial thickness of the multi-layered coating. In yet another aspect, a medical device has a polymer layer comprising a block co-polymer, wherein the polymer layer contains a therapeutic agent, and a barrier layer disposed over the polymer layer, wherein the barrier layer comprises an inorganic material, and wherein the barrier layer has a plurality of discontinuities. Methods of forming coatings on medical devices and methods of delivering therapeutic agents to body sites are also disclosed.
摘要翻译：在一个方面，医疗装置具有第一构造和第二构造，包含治疗剂的贮存器和设置在贮存器上方的阻挡层，其中阻挡层包括无机材料。在另一方面，医疗装置具有容纳治疗剂的储存器，设置在贮存器上方的阻挡层，其中所述阻挡层包括无机材料，以及设置在所述阻挡层和所述医疗装置的表面之间的可溶胀材料，其中可膨胀材料是暴露于含水环境时膨胀的材料。在另一方面，医疗装置具有多层涂层，其具有交替的储层和阻挡层，以及穿透多层涂层的至少部分厚度的多个挖掘区域。在另一方面，医疗装置具有包含嵌段共聚物的聚合物层，其中所述聚合物层含有治疗剂，以及设置在所述聚合物层上的阻挡层，其中所述阻挡层包含无机材料，并且其中阻挡层具有多个不连续性。还公开了在医疗装置上形成涂层的方法和将治疗剂递送到身体部位的方法。

32. 发明申请

WO2008156666A3 HARDENED POLYMERIC LUMEN SURFACES 审中-公开
标题翻译：硬化聚合物表面
公开(公告)号：WO2008156666A3
公开(公告)日：2009-02-12
申请号：PCT/US2008007396
申请日：2008-06-13
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN
发明人： WEBER JAN
IPC分类号： A61M25/00
CPC分类号： A61M25/0045 , A61L29/04 , A61L29/14 , A61L2400/18 , A61M25/0009 , A61M25/0023 , A61M25/0054 , A61M2025/0062
摘要： Apparatuses, systems, and methods for surface modification of catheters. The surface modification can be localized to a lumen surface (114) of the catheter (100). The surface modification to the lumen surface extends radially into the catheter body a predetermined distance to provide a hardened zone (118) having a hardness that is greater than a hardness of an exterior surface (104) of the catheter body (102).
摘要翻译：导管表面改性的装置，系统和方法。表面改性可以定位于导管（100）的内腔表面（114）。对内腔表面的表面修饰径向延伸到导管体中预定距离，以提供具有大于导管主体（102）的外表面（104）的硬度的硬度的硬化区（118）。

33. 发明申请

WO2009018037A2 MEDICAL DEVICES COMPRISING POROUS INORGANIC FIBERS FOR THE RELEASE OF THERAPEUTIC AGENTS 审中-公开
标题翻译：包含用于释放治疗药物的多孔无机纤维的医疗装置
公开(公告)号：WO2009018037A2
公开(公告)日：2009-02-05
申请号：PCT/US2008070844
申请日：2008-07-23
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN , KOKATE JAYDEEP Y , IFTEKAR ARIF
发明人： WEBER JAN , KOKATE JAYDEEP Y , IFTEKAR ARIF
IPC分类号： A61L31/02 , A61L31/10 , A61L31/16
CPC分类号： A61L31/16 , A61L31/022 , A61L31/10 , A61L2300/00
摘要： In accordance with an aspect of the invention, implantable or insertable medical devices are provided which comprise a substrate and a therapeutic-agent-loaded porous inorganic fiber.
摘要翻译：根据本发明的一个方面，提供了可植入或可插入的医疗装置，其包括基底和负载治疗剂的多孔无机纤维。

34. 发明申请

WO2008057991A3 ION BOMBARDMENT OF MEDICAL DEVICES 审中-公开
标题翻译：医疗器械的离子BOMBARDMENT
公开(公告)号：WO2008057991A3
公开(公告)日：2008-10-30
申请号：PCT/US2007083432
申请日：2007-11-02
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN , SCHEVCHENKO NATALIA
发明人： WEBER JAN , SCHEVCHENKO NATALIA
IPC分类号： A61F2/86
CPC分类号： A61F2/86 , A61C8/0012 , A61C8/0018 , A61C8/0039 , A61C2008/0046 , A61F2/91 , A61F2/915 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2210/0076 , A61F2250/0024 , A61F2250/0068
摘要： A medical device can include a metal member including a porous first portion with pores extending from a surface of the metal member into the first portion and non-porous second portion. The first portion can have a porosity that varies with distance from the surface of the metal member.
摘要翻译：医疗装置可以包括金属构件，其包括具有从金属构件的表面延伸到第一部分中的孔的多孔第一部分和无孔第二部分。第一部分可以具有随着距离金属构件的表面的距离而变化的孔隙率。

35. 发明申请

WO2007149776A3 MEDICAL DEVICES INCLUDING COMPOSITES 审中-公开
标题翻译：包括复合材料的医疗器械
公开(公告)号：WO2007149776A3
公开(公告)日：2008-02-14
申请号：PCT/US2007071315
申请日：2007-06-15
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN , HOLMAN THOMAS J , EIDENSCHINK TRACEE
发明人： WEBER JAN , HOLMAN THOMAS J , EIDENSCHINK TRACEE
IPC分类号： A61F2/01 , A61F2/06 , A61F2/82
CPC分类号： A61F2/013 , A61F2/06 , A61F2/82 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/005 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2250/003
摘要： Medical devices, such as endoprostheses, and methods of making the devices are described. In some embodiments, a medical device includes an elongated hollow body formed of a polymeric matrix containing one or more regions of a pre-determined weight percent of carbon nanotubes in general alignment in a pre-determined orientation. The medical device can have a compressed state with a first transverse dimension and an expanded state with a second relatively greater transverse dimension.
摘要翻译：描述医疗装置，例如内用假体，以及制造装置的方法。在一些实施方案中，医疗装置包括由聚合物基质形成的细长中空体，其含有预定重量百分比的碳纳米管的一个或多个区域，以预定方向大致对准。医疗装置可以具有第一横向尺寸的压缩状态和具有第二较大横向尺寸的膨胀状态。

36. 发明申请

WO2007006043A3 MEDICAL DEVICES WITH MACHINED LAYERS FOR CONTROLLED COMMUNICATION WITH UNDERLYING REGIONS 审中-公开
标题翻译：具有加工层的医疗设备用于与相关地区的控制通信
公开(公告)号：WO2007006043A3
公开(公告)日：2007-02-22
申请号：PCT/US2006026491
申请日：2006-07-05
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN , HOLMAN THOMAS J
发明人： WEBER JAN , HOLMAN THOMAS J
IPC分类号： A61F2/00
CPC分类号： A61L27/50
摘要： According to an aspect of the present invention, implantable or insertable medical devices (100) (also referred to as internal medical devices) are provided. These medical devices include at least one machined layer (110) , at least a portion of which is disposed over at least one underlying region (120) (e.g. , a therapeutic agent containing region, a catalytic region, etc.) . The at least one machined layer contains a plurality of excavated regions which promote the transport of molecular species across the machined layer. An advantage of the present invention is that medical devices are provided, in which the transport of species into the medical device, out of the medical device, or both are controlled, and may be customized, as desired.
摘要翻译：根据本发明的一个方面，提供了可植入或可插入的医疗装置（100）（也称为内部医疗装置）。这些医疗装置包括至少一个加工层（110），其至少一部分设置在至少一个下面的区域（120）（例如含治疗剂的区域，催化区域等）上。所述至少一个加工层包含多个挖掘区域，其促进分子物质跨过加工层的运输。本发明的一个优点是提供了医疗装置，其中可以根据需要将物种运送到医疗装置，医疗装置或两者中进行控制，并且可以被定制。

37. 发明申请

WO2006042260A3 REINFORCED AND DRUG-ELUTING BALLOON CATHETERS AND METHODS FOR MAKING SAME 审中-公开
标题翻译：增强药物和药物缓释气囊导管及其制造方法
公开(公告)号：WO2006042260A3
公开(公告)日：2006-09-08
申请号：PCT/US2005036625
申请日：2005-10-12
申请人： BOSTON SCIENT SCIMED INC , HOLMAN THOMAS J , WEBER JAN , SCHEWE SCOTT
发明人： HOLMAN THOMAS J , WEBER JAN , SCHEWE SCOTT
IPC分类号： A61F2/958 , A61M25/00
CPC分类号： A61M25/1029 , A61M25/10 , A61M25/1002 , A61M25/1034 , A61M25/1038 , A61M2025/0058 , A61M2025/1031 , A61M2025/105 , A61M2025/1084
摘要： The present invention generally relates to the field of intravascular medical devices, and more specifically to the field of balloon catheters and other similar diagnostic or therapeutic catheters within the body for treatment and diagnosis of diseases. In particular, the present invention relates to reinforced balloon catheters and drug-eluting balloon catheters and corresponding methods for producing same.
摘要翻译：本发明总体上涉及血管内医疗装置领域，并且更具体地涉及用于治疗和诊断疾病的球囊导管和其他类似的诊断或治疗导管领域。特别地，本发明涉及加强的球囊导管和药物洗脱球囊导管以及用于生产它们的相应方法。

38. 发明申请

WO2005113033A3 MEDICAL DEVICES AND METHODS OF MAKING THE SAME 审中-公开
标题翻译：医疗器械及其制造方法
公开(公告)号：WO2005113033A3
公开(公告)日：2006-03-02
申请号：PCT/US2005017565
申请日：2005-05-19
申请人： BOSTON SCIENT SCIMED INC , WEBER JAN , HOLMAN THOMAS J
发明人： WEBER JAN , HOLMAN THOMAS J
IPC分类号： A61F2/00 , A61L2/00 , A61L27/30 , A61L27/44 , A61L29/10 , A61L29/12 , A61L31/08 , A61L31/12 , B05D3/00 , B05D3/06
CPC分类号： A61L27/303 , A61F2002/30067 , A61F2310/00574 , A61L27/443 , A61L29/103 , A61L29/126 , A61L31/084 , A61L31/126 , A61L2400/12 , B82Y30/00
摘要： Medical devices including carbon nanotubes and methods of making the devices are described. In some embodiments, the nanotubes are bonded together, for example, by irradiation with electrons and/or ions.
摘要翻译：描述了包括碳纳米管在内的医疗装置及其制造方法。在一些实施方案中，例如通过用电子和/或离子照射将纳米管结合在一起。

39. 发明申请

WO2011022623A3 MEDICAL DEVICES CONTAINING THERAPEUTIC AGENTS 审中-公开
标题翻译：含有治疗药物的医疗器械
公开(公告)号：WO2011022623A3
公开(公告)日：2011-07-28
申请号：PCT/US2010046125
申请日：2010-08-20
申请人： BOSTON SCIENT SCIMED INC , HINGSTON JOHN , ROBICHAUD MICHAEL , WEBER JAN , MCNAMARA ADRIAN , FLANAGAN AIDEN , HORGAN FERGAL
发明人： HINGSTON JOHN , ROBICHAUD MICHAEL , WEBER JAN , MCNAMARA ADRIAN , FLANAGAN AIDEN , HORGAN FERGAL
IPC分类号： A61L31/08 , A61L31/14 , A61L31/16
CPC分类号： A61L31/088 , A61L31/14 , A61L31/146 , A61L31/16 , A61L2400/12
摘要： According to one aspect of the invention, implantable or insertable medical devices are provided which can delay release of one or more therapeutic agents for a predetermined time after implantation in a subject. In various embodiments, a therapeutic agent delivery profile of this type is provided by employing a temporary barrier layer which initially permits little to no release of the therapeutic agent, but which layer permits much greater release levels after a predetermined period of time. Other aspects of the invention relate to methods of forming such devices and to methods of using such devices.
摘要翻译：根据本发明的一个方面，提供了可植入或可插入的医疗装置，其可以在植入受试者之后延迟一个或多个治疗剂释放预定时间。在各种实施方案中，通过采用临时阻挡层来提供这种类型的治疗剂递送分布，该临时阻挡层最初允许治疗剂很少或不释放，但是哪个层在预定时间段之后允许更大的释放水平。本发明的其它方面涉及形成这种装置的方法以及使用这种装置的方法。

40. 发明申请

WO2011011207A3 MEDICAL DEVICES HAVING AN INORGANIC COATING LAYER FORMED BY ATOMIC LAYER DEPOSITION 审中-公开
标题翻译：具有由原子层沉积形成的无机涂层的医疗设备
公开(公告)号：WO2011011207A3
公开(公告)日：2011-04-21
申请号：PCT/US2010041348
申请日：2010-07-08
申请人： BOSTON SCIENT SCIMED INC , FLANAGAN AIDEN , WEBER JAN
发明人： FLANAGAN AIDEN , WEBER JAN
IPC分类号： A61L31/08 , A61L31/14 , A61L31/16
CPC分类号： A61L31/082 , A61L31/146 , A61L31/148 , A61L31/16 , Y10T428/265
摘要： Medical devices having a coating that comprises one or more inorganic coating layers. The inorganic coating layer may be formed by a self-limiting deposition process, such as atomic layer deposition. The inorganic coating layer may have a thickness of less than 30 nm. The inorganic coating layer may also be used in combination with a therapeutic agent as a control release barrier. The inorganic coating layer may have various desirable properties, including, for example, resistance to cracking or delamination, high degree of uniformity, high degree of conformality, and/or compatibility with low deposition temperatures.
摘要翻译：具有包含一个或多个无机涂层的涂层的医疗装置。无机涂层可以通过自限性沉积工艺形成，例如原子层沉积。无机涂层可以具有小于30nm的厚度。无机涂层也可以与治疗剂组合使用作为控制释放屏障。无机涂层可具有各种期望的性质，包括例如抗裂化或分层，高度均匀性，高度共形性和/或与低沉积温度的兼容性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式