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31. 发明专利

JP2005255976A Composition for solubilizing lipid 审中-公开
标题翻译：用于溶解脂质的组合物
公开(公告)号：JP2005255976A
公开(公告)日：2005-09-22
申请号：JP2004343205
申请日：2004-11-26
申请人： Bausch & Lomb Inc , ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated
发明人： HU ZHENZE , SALAMONE JOSEPH C
IPC分类号： G02C7/04 , A61L12/14 , C11D1/00 , C11D1/40 , C11D1/66 , C11D1/72 , C11D1/825 , C11D1/835 , C11D3/00 , C11D3/04 , C11D3/06 , C11D3/20 , C11D3/37 , C11D3/48 , G02C13/00
CPC分类号： C11D3/0078 , A61L12/14 , C11D1/008 , C11D1/40 , C11D1/72 , C11D1/825 , C11D1/835
摘要： PROBLEM TO BE SOLVED: To find a contact lens cleaning solution effective in removing lipid stains without causing ocular irritation.
SOLUTION: The composition is provided for preventing, removing or reducing lipid deposits on medical devices, and employing two nonionic surfactants having HLBs greater than about 18 with the nonionic surfactant having a greater HLB present in an amount about twice that of the nonionic surfactant having a lower HLB.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：找到有效去除脂质污渍而不引起眼睛刺激的隐形眼镜清洁溶液。提供了用于预防，去除或减少医疗装置上的脂质沉积物的组合物，并且使用具有大于约18的HLB的两种非离子表面活性剂，其中HLB存在的非离子表面活性剂的量为非离子表面活性剂的大约两倍具有较低HLB的表面活性剂。版权所有（C）2005，JPO＆NCIPI

32. 发明公开

EP1027015A4 CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE 失效
标题翻译：药品杂志在前面的眼睛室的控制分布
公开(公告)号：EP1027015A4
公开(公告)日：2001-06-27
申请号：EP98910483
申请日：1998-03-18
申请人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
发明人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
IPC分类号： A61F2/14 , A61F9/00 , A61K9/00 , A61K31/137 , A61K31/221 , A61K31/4178 , A61K31/46 , A61K31/728 , A61K31/765 , A61L31/04 , A61L31/16
CPC分类号： A61K31/46 , A61F9/00 , A61K9/0048 , A61K31/137 , A61K31/221 , A61K31/4178 , A61K31/728 , A61K31/765 , A61L31/042 , A61L31/048 , A61L31/16 , A61L2300/402 , A61L2300/45 , A61L2430/16 , A61K2300/00

33. 发明专利

DK0601055T3 未知
公开(公告)号：DK0601055T3
公开(公告)日：2000-10-02
申请号：DK92918851
申请日：1992-08-13
申请人： SALAMONE JOSEPH C , GALIN MILES A , ISRAEL STANLEY C
发明人： SALAMONE JOSEPH C , GALIN MILES A , ISRAEL STANLEY C
IPC分类号： A61F2/14 , A61L27/00 , A61L27/34 , A61L33/00
摘要： A minus power anterior chamber ocular implant for placement in the anterior chamber of a phakic eye having an anatomic lens in situ comprises a negative artificial refracting lens having at least one concave surface, a surface coating which comprises a compatible sulfated polysaccharide medicament coating, such as heparin, and having a structure which positions the artificial lens in the anterior chamber of the eye to prevent contact between the implant and the anatomic lens. The implant compensates for refractive errors or creates a specific refraction to assist in visual function and has increased biocompatibility in the anterior chamber of the eye, thereby preventing or mitigating detrimental effects typically associated with the implantation of an uncoated refractive anterior chamber implant in the eye. A method of preparing such a minus power anterior chamber ocular implant comprises first exposing an uncoated implant to a plasma to generate a plasma-treated implant having a surface containing amines, carboxylic acids, active free radicals or passive free radicals, and thereafter bonding the medicament to the plasma-treated implant surface. A method of treating myopia comprises surgically implanting and anchoring the implant in the phakic eye to compensate for refractive errors.

34. 发明专利

NO994485L 未知
公开(公告)号：NO994485L
公开(公告)日：1999-11-16
申请号：NO994485
申请日：1999-09-16
申请人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
发明人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
IPC分类号： A61F2/14 , A61F9/00 , A61K9/00 , A61K31/137 , A61K31/221 , A61K31/4178 , A61K31/46 , A61K31/728 , A61K31/765 , A61L31/04 , A61L31/16
摘要： The present invention relates to compositions which maintain the structural integrity of the anterior chamber of the eye during ophthalmologic surgery, thereby protecting the tissues that form and line the anterior segment from potential damage and simultaneously providing sustained delivery of pharmaceuticals, including miotic, mydriatic, or anesthetic agents.

35. 发明专利

AU707013B2 Controlled release of miotic and mydriatic drugs in the anterior chamber 未知
公开(公告)号：AU707013B2
公开(公告)日：1999-07-01
申请号：AU5555796
申请日：1996-04-18
申请人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
发明人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
IPC分类号： A61K9/107 , A61F9/00 , A61K9/00 , A61K9/50 , A61K31/137 , A61K31/165 , A61K31/221 , A61K31/415 , A61K31/4178 , A61K31/46 , A61K31/715 , A61K31/728 , A61K31/74 , A61K31/765 , A61K45/00 , A61K47/30 , A61L31/04 , A61P27/02 , A61P27/06 , A61P27/08 , A61K47/36 , A61F2/14
摘要： The present invention relates to compositions which maintain the structural integrity of the anterior chamber of the eye during ophthalmologic surgery, thereby protecting the tissues that form and line the anterior segment from potential damage and simultaneously providing sustained delivery of a miotic or mydriatic agent. The present invention provides for compositions which comprise a viscoelastic polymer, wherein sustained release of a miotic or mydriatic agent is mediated by ionic interactions, as well as for compositions wherein sustained release of a miotic or mydriatic agent is mediated by microcapsules or copolymer micelles.

36. 发明专利

CZ326497A3 COMPOSITION USABLE IN EYE SURGERY 未知
公开(公告)号：CZ326497A3
公开(公告)日：1998-09-16
申请号：CZ326497
申请日：1996-04-18
申请人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
发明人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
IPC分类号： A61K9/107 , A61F9/00 , A61K9/00 , A61K9/50 , A61K31/137 , A61K31/165 , A61K31/221 , A61K31/415 , A61K31/4178 , A61K31/46 , A61K31/715 , A61K31/728 , A61K31/74 , A61K31/765 , A61K45/00 , A61K47/30 , A61L31/04 , A61P27/02 , A61P27/06 , A61P27/08 , A61K47/36 , A61F2/14
摘要： The present invention relates to compositions which maintain the structural integrity of the anterior chamber of the eye during ophthalmologic surgery, thereby protecting the tissues that form and line the anterior segment from potential damage and simultaneously providing sustained delivery of a miotic or mydriatic agent. The present invention provides for compositions which comprise a viscoelastic polymer, wherein sustained release of a miotic or mydriatic agent is mediated by ionic interactions, as well as for compositions wherein sustained release of a miotic or mydriatic agent is mediated by microcapsules or copolymer micelles.

37. 发明专利

PL322820A1 CONTROLLABLE RELEASE IN ANTERIOR EYE CHAMBER OF MEDICINES HAVING PUPIL WIDENING AND NARROWING EFFECTS 未知
公开(公告)号：PL322820A1
公开(公告)日：1998-02-16
申请号：PL32282096
申请日：1996-04-18
申请人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
发明人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
IPC分类号： A61F9/00 , A61K9/107 , A61K9/00 , A61K9/50 , A61K31/137 , A61K31/165 , A61K31/221 , A61K31/415 , A61K31/4178 , A61K31/46 , A61K31/715 , A61K31/728 , A61K31/74 , A61K31/765 , A61K45/00 , A61K47/30 , A61L31/04 , A61P27/02 , A61P27/06 , A61P27/08
摘要： The present invention relates to compositions which maintain the structural integrity of the anterior chamber of the eye during ophthalmologic surgery, thereby protecting the tissues that form and line the anterior segment from potential damage and simultaneously providing sustained delivery of a miotic or mydriatic agent. The present invention provides for compositions which comprise a viscoelastic polymer, wherein sustained release of a miotic or mydriatic agent is mediated by ionic interactions, as well as for compositions wherein sustained release of a miotic or mydriatic agent is mediated by microcapsules or copolymer micelles.

38. 发明专利

NO974808A 未知
公开(公告)号：NO974808A
公开(公告)日：1997-12-15
申请号：NO974808
申请日：1997-10-17
申请人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
发明人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
IPC分类号： A61K9/107 , A61F9/00 , A61K9/00 , A61K9/50 , A61K31/137 , A61K31/165 , A61K31/221 , A61K31/415 , A61K31/4178 , A61K31/46 , A61K31/715 , A61K31/728 , A61K31/74 , A61K31/765 , A61K45/00 , A61K47/30 , A61L31/04 , A61P27/02 , A61P27/06 , A61P27/08 , A61K9/08 , A61K47/36
CPC分类号： A61L31/048 , A61F9/00 , A61K9/0048 , A61K31/137 , A61K31/221 , A61K31/4178 , A61K31/46 , A61K31/728 , A61K31/765 , Y10S514/912 , A61K31/74 , A61K31/135 , A61K2300/00

39. 发明专利

BR9206365A 未知
公开(公告)号：BR9206365A
公开(公告)日：1994-10-11
申请号：BR9206365
申请日：1992-08-13
申请人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
发明人： GALIN MILES A , SALAMONE JOSEPH C , ISRAEL STANLEY C
IPC分类号： A61F2/14 , A61L27/00 , A61L27/34 , A61L33/00
摘要： A minus power anterior chamber ocular implant for placement in the anterior chamber of a phakic eye having an anatomic lens in situ comprises a negative artificial refracting lens having at least one concave surface, a surface coating which comprises a compatible sulfated polysaccharide medicament coating, such as heparin, and having a structure which positions the artificial lens in the anterior chamber of the eye to prevent contact between the implant and the anatomic lens. The implant compensates for refractive errors or creates a specific refraction to assist in visual function and has increased biocompatibility in the anterior chamber of the eye, thereby preventing or mitigating detrimental effects typically associated with the implantation of an uncoated refractive anterior chamber implant in the eye. A method of preparing such a minus power anterior chamber ocular implant comprises first exposing an uncoated implant to a plasma to generate a plasma-treated implant having a surface containing amines, carboxylic acids, active free radicals or passive free radicals, and thereafter bonding the medicament to the plasma-treated implant surface. A method of treating myopia comprises surgically implanting and anchoring the implant in the phakic eye to compensate for refractive errors.

40. 发明申请

WO2007022377A3 CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL 审中-公开
标题翻译：适合的溶剂基带状涂层和涂层材料
公开(公告)号：WO2007022377A3
公开(公告)日：2007-10-25
申请号：PCT/US2006032178
申请日：2006-08-17
申请人： SALAMONE ANN BEAL , SALAMONE JOSEPH C
发明人： SALAMONE ANN BEAL , SALAMONE JOSEPH C
IPC分类号： A61K31/785
CPC分类号： A61L26/0019 , A61K31/785 , A61L24/0021 , A61L24/043 , A61L24/06 , C08L35/04
摘要： Liquid hemostatic coating materials comprise a cyanoacrylate monomer and a solvent system comprising a volatile, non-reactive liquid that is non-stinging and non-irritating to a user. The material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.
摘要翻译：液体止血涂层材料包含氰基丙烯酸酯单体和溶剂体系，所述溶剂体系包含对使用者无刺激和无刺激性的挥发性非反应性液体。该材料形成薄膜形式的涂层或绷带，当涂覆并粘附到使用者的表面或皮肤上时，抑制涂抹表面粘附到另一表面。

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