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31. 发明授权

US07724021B2 Method and device for programmable power supply with configurable restrictions 有权
标题翻译：具有可配置限制的可编程电源的方法和装置
公开(公告)号：US07724021B2
公开(公告)日：2010-05-25
申请号：US12194955
申请日：2008-08-20
申请人： Martin Krueger , Erwin Huber , Jens Barrenscheen
发明人： Martin Krueger , Erwin Huber , Jens Barrenscheen
IPC分类号： H03K19/00
CPC分类号： G06F1/26
摘要： The invention involves a programmable power supply device with configurable restrictions to the programmability of the power supply device, wherein the programmable power supply device comprises a number of freeze/programmability levels, each freeze/programmability defining a dedicated access restriction to the programmability of the power supply device.
摘要翻译：本发明涉及一种可编程电源设备，其具有对电源设备的可编程性的可配置限制，其中可编程电源设备包括多个冻结/可编程性水平，每个冻结/可编程性定义了对电源的可编程性的专用访问限制供应装置。

32. 发明申请

US20080176833A1 DIHYDROPYRIDINE DERIVATIVES AS USEFUL AS PROTEIN KINASE INHIBITORS 有权
标题翻译：作为蛋白激酶抑制剂有用的二氢吡啶衍生物
公开(公告)号：US20080176833A1
公开(公告)日：2008-07-24
申请号：US11955777
申请日：2007-12-13
申请人： Marc Adler , Stefan Baeurle , Judi Bryant , Ming Chen , Yuo-Ling Chou , Paul Hrvatin , Seock-Kyu Khim , Monica Kochanny , Wheeseong Lee , Michael Mamounas , Janet Meurer Ogden , Gary Bruce Phillips , Victor Selchau , Christopher West , Bin Ye , Shendong Yuan , Martin Krueger
发明人： Marc Adler , Stefan Baeurle , Judi Bryant , Ming Chen , Yuo-Ling Chou , Paul Hrvatin , Seock-Kyu Khim , Monica Kochanny , Wheeseong Lee , Michael Mamounas , Janet Meurer Ogden , Gary Bruce Phillips , Victor Selchau , Christopher West , Bin Ye , Shendong Yuan , Martin Krueger
IPC分类号： A61K31/55 , C07D213/02 , A61K31/4427 , C07D455/02 , A61K31/4375 , C07D295/00 , A61K31/5377 , A61P35/00 , C07D239/24 , A61K31/506 , C07D221/00 , A61K31/496 , C07D223/02
CPC分类号： C07D401/04 , C07D211/90 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/10 , C07D409/14 , C07D413/14 , C07D471/04
摘要： This invention provides novel dihydropyridine derivatives of the formula I having protein tyrosine kinase inhibitory activity, to process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions.
摘要翻译：本发明提供具有蛋白酪氨酸激酶抑制活性的新颖的具有蛋白酪氨酸激酶抑制活性的二氢吡啶衍生物，其制备方法及其用于治疗c-Met介导的疾病或c-Met介导的病症的用途。

33. 发明申请

US20080064696A1 SUBSTITUTED SULPHOXIMINES AS TIE2 INHIBITORS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME 有权
标题翻译：替代的硫霉素作为TIE2抑制剂及其制备方法，包含其的药物组合物，其制备方法及其用途
公开(公告)号：US20080064696A1
公开(公告)日：2008-03-13
申请号：US11776231
申请日：2007-07-11
申请人： Ingo Hartung , Georg Kettschau , Hans Briem , Karl-Heinz Thierauch , Ulrich Luecking , Ulf Boemer , Martin Krueger
发明人： Ingo Hartung , Georg Kettschau , Hans Briem , Karl-Heinz Thierauch , Ulrich Luecking , Ulf Boemer , Martin Krueger
IPC分类号： C07D239/28 , A61K31/496 , A61K31/505 , A61K31/5377 , C07D403/12 , C07D413/12 , A61P19/00 , A61P35/00 , A61P9/00
CPC分类号： C07D239/48 , C07D239/47 , C07D401/12 , C07D407/12 , C07D413/12
摘要： The invention relates to substituted sulphoximines according to the general formula (I): in which A, E, G, X, R1, R2, R3, R4, R5, R6, R7, R8, m, p, q, are given in the claims, and salts thereof, to pharmaceutical compositions comprising said substituted sulphoximines, to methods of preparing said substituted sulphoximines as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.
摘要翻译：本发明涉及根据通式（I）的取代的亚磺酰亚胺：其中A，E，G，X，R 1，R 2，R 3 R 4，R 5，R 5，R 6，R 7，R 8，权利要求书中给出m，p，q及其盐，包含所述取代的亚硫酰亚胺的药物组合物，制备所述取代的亚硫酰亚胺的方法及其制备用于治疗的药物组合物的用途的血管生长失调的疾病或伴有血管生长紊乱的疾病，其中所述化合物有效地干扰Tie2信号传导。

34. 发明授权

US07338958B2 Sulfoximine-substituted pyrimidines as CDK-and/or VEGF inhibitors, their production and use as pharmaceutical agents 有权
标题翻译：磺酰亚胺取代的嘧啶作为CDK和/或VEGF抑制剂，其生产和用作药剂
公开(公告)号：US07338958B2
公开(公告)日：2008-03-04
申请号：US10966098
申请日：2004-10-18
申请人： Ulrich Luecking , Gerhard Siemeister , Martin Krueger , Rolf Jautelat
发明人： Ulrich Luecking , Gerhard Siemeister , Martin Krueger , Rolf Jautelat
IPC分类号： A61K31/506 , C07D239/34 , C07D239/38 , C07D239/48 , A61P35/00 , C07D239/30 , C07D239/56 , C07C315/04 , C07C317/14 , C07C307/02 , C07C311/07
CPC分类号： C07D239/47 , C07D239/48
摘要： This invention relates to pyrimidine derivatives of general formula I in which Q, R1, R2, R3, R4, R5, X, and m have the meanings that are contained in the description, as inhibitors of cyclin-dependent kinases and VEGF-receptor tyrosine kinases, their production as well as their use as medications for treatment of various diseases.
摘要翻译：本发明涉及通式I的嘧啶衍生物，其中Q，R 1，R 2，R 3，R 4， R 5，X 5和m具有说明书中所含的含义，作为细胞周期蛋白依赖性激酶和VEGF-受体酪氨酸激酶的抑制剂，其生产及其用途用于治疗各种疾病的药物。

35. 发明申请

US20140259404A1 Sculpture blanket or bendy blanket 审中-公开
标题翻译：雕塑毯或弯曲的毯子
公开(公告)号：US20140259404A1
公开(公告)日：2014-09-18
申请号：US13799161
申请日：2013-03-13
申请人： Monika Ingwelda Walker , Martin Krueger
发明人： Monika Ingwelda Walker , Martin Krueger
IPC分类号： A47G9/02
CPC分类号： A47G9/0223 , A47D13/083 , A47G9/062 , A61G7/0501 , A61G7/0525
摘要： The sculpture or bendy blanket has a resilient bendable grid frame assembly which allows the sculpture blanket to have all the properties of any blanket and a new aspect of the ability to independently hold usual and unusual forms and shapes. The sculpture blanket is bendable, resilient, able to be sculpted and molded, is formable, adjustable, and able to be articulated into a multitude number of abstract and unusual nonstandard forms for fabric material, and hold its shape until manipulated into a new form by the user; while at the same time provides coziness, warmth, entertainment and protection against environmental elements. The sculpture blanket is resilient, and therefore, constructed using a material that has a property that will allow it to be bent and reformed repeatedly, without damaging the frame, of the frame losing its properties over time to bend or hold the desired shape.
摘要翻译：雕塑或弯曲的毯子具有弹性可弯曲的网格框架组件，其允许雕塑毯具有任何毯子的所有属性和独立地保持通常和不寻常的形状和形状的能力的新方面。雕塑毯是可弯曲的，有弹性的，能够雕刻和模制，可成形，可调节，并且能够被铰接成多种抽象和异常的非标准形式的织物材料，并保持其形状，直到被操纵成新的形式用户; 同时为环境要素提供舒适，温暖，娱乐和保护。雕塑毯是弹性的，因此使用具有这样一种特性的材料来构造，该材料将使其能够在不损坏框架的情况下反复弯曲和重新变形，而不会随着时间推移而失去其特性以弯曲或保持所需形状。

36. 发明授权

US08003655B2 Substituted sulphoximines as TIE2 inhibitors and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same 有权
标题翻译：作为TIE2抑制剂及其盐的取代的亚磺酰亚胺，包含其的药物组合物，其制备方法及其用途
公开(公告)号：US08003655B2
公开(公告)日：2011-08-23
申请号：US11776231
申请日：2007-07-11
申请人： Ingo Hartung , Georg Kettschau , Hans Briem , Karl-Heinz Thierauch , Ulrich Luecking , Ulf Boemer , Martin Krueger
发明人： Ingo Hartung , Georg Kettschau , Hans Briem , Karl-Heinz Thierauch , Ulrich Luecking , Ulf Boemer , Martin Krueger
IPC分类号： C07D439/02 , C07D239/42 , A01N43/54
CPC分类号： C07D239/48 , C07D239/47 , C07D401/12 , C07D407/12 , C07D413/12
摘要： The invention relates to substituted sulphoximines according to the general formula (I): in which A, E, G, X, R1, R2, R3, R4, R5, R6, R7, R8, m, p, q, are given in the claims, and salts thereof, to pharmaceutical compositions comprising said substituted sulphoximines, to methods of preparing said substituted sulphoximines as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.
摘要翻译：本发明涉及根据通式（I）的取代的亚磺酰亚胺：其中A，E，G，X，R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8，m，p，q，权利要求书及其盐，涉及包含所述取代的亚硫酰亚胺的药物组合物，制备所述取代的亚硫酰亚胺的方法及其用于制备用于治疗失调的血管生长疾病或伴随失调的疾病的药物组合物的用途血管生长，其中所述化合物有效地干扰Tie2信号传导。

37. 发明授权

US07668977B2 Method for exchanging information between devices connected via a communication link 有权
标题翻译：在通过通信链路连接的设备之间交换信息的方法
公开(公告)号：US07668977B2
公开(公告)日：2010-02-23
申请号：US11854270
申请日：2007-09-12
申请人： Martin Krueger , Erwin Huber
发明人： Martin Krueger , Erwin Huber
IPC分类号： G06F3/00
CPC分类号： H04L12/66
摘要： A method for exchanging information between a first device and a second device connected via a communication link, the communication link supporting a query command and at least a further command, where each command includes a specific command code is described. The method comprises transmitting a query command code and data from the first device via the communication link, the data identifying a specific command, receiving the query command code and the data at the second device, transmitting reply data from the second device via the communication link, the reply data including at least a first segment and a second segment, and receiving the reply data at the first device, wherein the first segment includes information whether the specific command is supported, wherein, if the specific command is not supported, the second segment includes information identifying an alternative command to the specific command.
摘要翻译：一种用于在通过通信链路连接的第一设备和第二设备之间交换信息的方法，支持查询命令的通信链路和至少另外的命令，其中每个命令包括特定命令代码。该方法包括经由通信链路从第一设备发送查询命令代码和数据，识别特定命令的数据，在第二设备接收查询命令代码和数据，经由通信链路从第二设备发送回复数据所述回复数据至少包括第一段和第二段，并且在所述第一设备处接收所述回复数据，其中所述第一段包括是否支持所述特定命令的信息，其中，如果所述特定命令不被支持，则所述第二段段包括识别特定命令的替代命令的信息。

38. 发明申请

US20090099219A1 ALKYNYLPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME 失效
标题翻译：亚苄基嘧啶及其盐，其包含其的药物组合物，其制备方法及其用途
公开(公告)号：US20090099219A1
公开(公告)日：2009-04-16
申请号：US12142279
申请日：2008-06-19
申请人： Ingo Hartung , Ulrich Bothe , Georg Kettschau , Ulrich Luecking , Anne Mengel , Martin Krueger , Karl Heinz Thierauch , Philip Lienau , Ulf Boemer
发明人： Ingo Hartung , Ulrich Bothe , Georg Kettschau , Ulrich Luecking , Anne Mengel , Martin Krueger , Karl Heinz Thierauch , Philip Lienau , Ulf Boemer
IPC分类号： A61K31/505 , A61P9/00 , A61P35/00 , A61P29/00 , A61P9/10 , C07D239/48 , C07D403/10 , C07D401/10 , A61K31/506
CPC分类号： C07D239/48 , C07D401/06 , C07D403/06
摘要： The invention relates to alkynylpyrimidines according to the general formula (I): in which A, R1, R2, R3, R4, R5, and R6 are as defined in the claims, and salts, N-oxides, metabolites, solvates, tautomers and prodrugs thereof, to pharmaceutical compositions comprising said alkynylpyrimidines, to methods of preparing said alkynylpyrimidines, as well as to uses thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 and VEGFR2 signalling.
摘要翻译：本发明涉及根据通式（I）的炔基嘧啶：其中A，R 1，R 2，R 3，R 4，R 5和R 6如权利要求中所定义，以及盐，N-氧化物，代谢物，溶剂合物，互变异构体和包含所述炔基嘧啶的药物组合物，制备所述炔基嘧啶的方法，及其制备用于治疗失调血管生长疾病的药物组合物或伴有血管生成失调的疾病的用途，其中，化合物有效地干扰Tie2和VEGFR2信号。

39. 发明申请

US20080181326A1 TRANSMITTER FOR COMMUNICATION SYSTEMS EMPLOYING AN ENHANCED MODULATION SCHEME 失效
标题翻译：使用增强调制方案的通信系统的发射机
公开(公告)号：US20080181326A1
公开(公告)日：2008-07-31
申请号：US12018380
申请日：2008-01-23
申请人： Martin Krueger , Holger Neuhaus , Burkhard Becker
发明人： Martin Krueger , Holger Neuhaus , Burkhard Becker
IPC分类号： H04L5/12 , H04L27/36
CPC分类号： H04L27/3488 , H04L27/0008
摘要： A transmitter is configured to transmit a transmit signal modulated according to a first modulation scheme, the first modulation scheme being associated with a set of first constellation points. The transmitter transmits at least a part of the transmit signal based on a subset of the first constellation points, wherein the subset of first constellation points approximates second constellation points of a set of second constellation points associated with a second modulation scheme. The first and second modulation schemes are different from one another.
摘要翻译：发射机被配置为发送根据第一调制方案调制的发射信号，所述第一调制方案与一组第一星座点相关联。所述发射机基于所述第一星座点的子集发射所述发射信号的至少一部分，其中所述第一星座点的子集近似于与第二调制方案相关联的一组第二星座点的第二星座点。第一和第二调制方案彼此不同。

40. 发明授权

US08198456B2 Dihydropyridine derivatives as useful as protein kinase inhibitors 有权
标题翻译：二氢吡啶衍生物可用作蛋白激酶抑制剂
公开(公告)号：US08198456B2
公开(公告)日：2012-06-12
申请号：US11955777
申请日：2007-12-13
申请人： Marc Adler , Stefan Baeurle , Judi Bryant , Ming Chen , Yuo-Ling Chou , Paul Hrvatin , Seock-Kyu Khim , Monica Kochanny , Wheeseong Lee , Michael Mamounas , Janet Meurer Ogden , Gary Bruce Phillips , Victor Selchau , Christopher West , Bin Ye , Shendong Yuan , Martin Krueger
发明人： Marc Adler , Stefan Baeurle , Judi Bryant , Ming Chen , Yuo-Ling Chou , Paul Hrvatin , Seock-Kyu Khim , Monica Kochanny , Wheeseong Lee , Michael Mamounas , Janet Meurer Ogden , Gary Bruce Phillips , Victor Selchau , Christopher West , Bin Ye , Shendong Yuan , Martin Krueger
IPC分类号： C07D401/04
CPC分类号： C07D401/04 , C07D211/90 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/10 , C07D409/14 , C07D413/14 , C07D471/04
摘要： This invention provides novel dihydropyridine derivatives of the formula I having protein tyrosine kinase inhibitory activity, to process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions.
摘要翻译：本发明提供具有蛋白酪氨酸激酶抑制活性的新颖的具有蛋白酪氨酸激酶抑制活性的二氢吡啶衍生物，其制备方法及其用于治疗c-Met介导的疾病或c-Met介导的病症的用途。

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