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31. 发明申请

WO2018160790A1 TRANSCATHETER MITRAL VALVE DESIGN 审中-公开
公开(公告)号：WO2018160790A1
公开(公告)日：2018-09-07
申请号：PCT/US2018/020370
申请日：2018-03-01
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： MOORE, Brandon L.
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/2454 , A61F2/2457 , A61F2220/0016 , A61F2230/0008 , A61F2230/0013 , A61F2230/0023 , A61F2230/0054 , A61F2250/0037 , A61F2250/0063
摘要： A prosthetic mitral valve (200) includes a collapsible and expandable stent (250) extending from an inflow end (210) to an outflow end (212). A collapsible and expandable valve assembly is disposed within the stent. The valve assembly includes a plurality of anterior leaflets (238a-c) and one posterior leaflet (236). The posterior leaflet has a larger surface area than any of the anterior leaflets. When implanted in the native mitral valve annulus, the smaller size of the anterior leaflets and the corresponding smaller size of an anterior portion of the stent (228) reduce the likelihood of interference with blood flowing through the native aortic valve (140), while also reducing the likelihood of ventricular fibrillation.

32. 发明申请

WO2018156908A1 FLEXIBLE TORQUE CABLE FOR DELIVERY OF MEDICAL DEVICES 审中-公开
公开(公告)号：WO2018156908A1
公开(公告)日：2018-08-30
申请号：PCT/US2018/019441
申请日：2018-02-23
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： PERSZYK, Brian , GALE, Caytlin
IPC分类号： A61M25/09 , A61B17/12 , A61M25/00 , A61B17/00 , A61F2/01
摘要： The present application describes delivery cables (200) for delivering a medical device (201). In one example, a delivery cable includes a flexible inner core (202), a proximal outer coil (210), and a distal outer coil (208). The proximal outer coil has a first rigidity. The distal outer coil surrounds at least a portion of a distal section (204) of the flexible inner core and has a second rigidity less than the first rigidity, thereby reducing bias placed on the medical device by the delivery cable.

33. 发明申请

WO2018085062A1 CATHETER WITH VARIABLE RADIUS LOOP 审中-公开
标题翻译：带有可变RADIUS环路的导管
公开(公告)号：WO2018085062A1
公开(公告)日：2018-05-11
申请号：PCT/US2017/057655
申请日：2017-10-20
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： NEMEC, Linda, Kay , KUEHN, Fos, Ulus
IPC分类号： A61B5/00 , A61B5/042 , A61B18/14
摘要： A catheter includes a body having a proximal region that extends along a longitudinal axis, a distal region predisposed into a loop via shaping wire, and a neck region between the proximal and distal regions. The loop is disposed in a plane generally orthogonal to the longitudinal axis. An activation wire is coupled to the distal region and to an actuator in a manner that allows a user to adjust the radius of the loop. The activation and shaping wires are contained within a tube-shaped constraint, such as a spring coil, within the neck in order to the neck from nodding when the activation wire is activated.
摘要翻译：导管包括具有沿着纵向轴线延伸的近侧区域，通过成形金属丝预先设置到环中的远侧区域以及在近侧区域和远侧区域之间的颈部区域的主体。该环设置在大致垂直于纵向轴线的平面中。激活丝以允许使用者调节环的半径的方式联接到远侧区域和致动器。激活线和成形线被包含在颈部内的管形约束物（例如弹簧线圈）内，以便当激活激活线被激活时使颈部点头。

34. 发明申请

WO2018071857A1 ABLATION CATHETER WITH INTERNALLY FIXED SUBELECTRODES 审中-公开
标题翻译：消融导管与内部固定子电极
公开(公告)号：WO2018071857A1
公开(公告)日：2018-04-19
申请号：PCT/US2017/056647
申请日：2017-10-13
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： SLIWA, John, W. , MORSE, Stephen, A.
IPC分类号： A61B18/18 , A61B18/00
CPC分类号： A61B18/1492 , A61B18/1206 , A61B2018/00029 , A61B2018/00083 , A61B2018/00101 , A61B2018/00351 , A61B2018/00577 , A61B2018/126 , A61B2018/1405 , A61B2018/1467 , A61B2218/002 , A61M25/007
摘要： Aspects of the present disclosure relate to electrophysiology catheters for cardiac medical procedures. More specifically, the instant disclosure relates to an ablation catheter for treating cardiac arrhythmias by ablating tissue, and having one or more subelectrodes internally fixed within the ablation catheter tip to capture electrophysiology characteristics of myocardial tissue in proximity to the one or more subelectrodes.
摘要翻译：本公开的方面涉及用于心脏医学程序的电生理学导管。更具体地说，本公开涉及用于通过消融组织来治疗心脏心律失常的消融导管，并且具有内部固定在消融导管顶端内的一个或多个子电极，以捕获靠近一个或多个子电极的心肌组织的电生理学特征。 p>

35. 发明申请

WO2018052927A1 PROSTHETIC HEART VALVE WITH PARAVALVULAR LEAK MITIGATION FEATURES 审中-公开
标题翻译：人造心脏瓣膜具有非常低的泄漏缓解特征
公开(公告)号：WO2018052927A1
公开(公告)日：2018-03-22
申请号：PCT/US2017/051258
申请日：2017-09-13
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： KALETA, Richard , HIGH, Keith
IPC分类号： A61F2/24
摘要： A prosthetic heart valve includes a collapsible and expandable stent (302, 402) and a valve assembly (140). A first cuff (306) is positioned on the lumenal or ablumenal surface of the stent. A second cuff (350, 550, 650) is positioned radially outward of the stent and the first cuff. The second cuff (650) may include apertures (653) that allow blood to pass through the second cuff into the spaces between the first and second cuffs. The second cuff (550, 550') may include a proximal edge (552) with notches (553, 553') that may be closed to create puckered areas (555, 555') in the second cuff to facilitate the movement of blood in the spaces between the first and second cuffs. The stent (402) may include struts (412c, 412d) adjacent the second cuff that bow inwardly to create space for blood to flow in the spaces between the two cuffs.
摘要翻译：假体心脏瓣膜包括可折叠和可扩张支架（302,402）和瓣膜组件（140）。第一套囊（306）位于支架的腔腔或腹腔表面上。第二箍带（350,550,650）位于支架和第一箍带的径向外侧。第二箍带（650）可以包括允许血液穿过第二箍带进入第一箍带和第二箍带之间的空间的孔（653）。第二封套（550,550'）可以包括具有凹口（553,553'）的近侧边缘（552），所述凹口可以被封闭以在第二封套中形成起皱区域（555,555'）以促进血液在第一和第二个袖口之间的空间。支架（402）可以包括邻近第二箍的支柱（412c，412d），其向内弯曲以形成用于血液在两个箍之间的空间中流动的空间。

36. 发明申请

WO2017197064A1 MITRAL VALVE DELIVERY DEVICE 审中-公开
标题翻译：二尖瓣输送装置
公开(公告)号：WO2017197064A1
公开(公告)日：2017-11-16
申请号：PCT/US2017/032071
申请日：2017-05-11
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： PERSZYK, Brian J.
IPC分类号： A61F2/24 , A61F2/95
摘要： A delivery device (10) for a prosthetic heart valve (70) may include a catheter assembly (16) and an operating handle (12). The catheter assembly may include an inner shaft (40) around which a compartment (57) is defined, and a distal sheath (48) having proximal and distal segments (56), (54). The handle (12) may include a first lead screw (30) coupled to the proximal segment (56), a second lead screw (32) coupled to the distal segment (54), a knob (36) rotatable relative to a housing (20), (22) of the handle and threadedly engaged with the first lead screw, and a coupling assembly (60). The coupling assembly (60) may have a first condition in which rotation of the knob (36) moves the first lead screw (30) but not the second lead screw (32), and a second condition in which rotation of the knob simultaneously moves the first and second lead screws.
摘要翻译：用于人工心脏瓣膜（70）的输送装置（10）可以包括导管组件（16）和操作手柄（12）。导管组件可以包括限定隔室（57）的内轴（40）和具有近端和远端节段（56），（54）的远端护套（48）。手柄（12）可以包括联接到近侧段（56）的第一导螺杆（30），联接到远侧段（54）的第二导螺杆（32），可相对于壳体旋转的旋钮（36） 20），手柄（22）并与第一导螺杆螺纹啮合;以及耦合组件（60）。联接组件60可以具有第一状态和第二状态，在第一状态中，旋钮36的旋转使第一导螺杆30而不是第二导螺杆32移动，在第二状态中，旋钮同时移动第一个和第二个螺丝。

37. 发明申请

WO2017196909A1 MITRAL HEART VALVE REPLACEMENT 审中-公开
标题翻译： MITRAL心脏瓣膜置换
公开(公告)号：WO2017196909A1
公开(公告)日：2017-11-16
申请号：PCT/US2017/031848
申请日：2017-05-10
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： DALE, Theodore P. , AHMANN, Katherine A. , PERSZYK, Brian J. , GLIMSDALE, Mathias C. , VIETMEIER, Kristopher H.
IPC分类号： A61F2/24
摘要： A prosthetic heart valve having an inflow end, an outflow end and a longitudinal axis extending from the inflow end to the outflow end includes a stent including a plurality of cells arranged in at least one row extending around a circumference of the stent. The stent further includes at least one engaging arm joined to one of the cells adjacent the outflow end and having a free end extending toward the inflow end, the engaging arm being movable between a loaded condition in which the engaging arm is oriented substantially parallel with the longitudinal axis of the stent, a partially-released condition in which the engaging arm forms a first angle with the longitudinal axis of the stent, and a fully-released condition in which the engaging arm forms a second angle with the longitudinal axis of the stent, the first angle being larger than the second angle.
摘要翻译：具有流入端，流出端和从流入端延伸到流出端的纵向轴线的假体心脏瓣膜包括支架，该支架包括布置成在至少一排中围绕支架周长。支架进一步包括至少一个接合臂，所述接合臂连接到邻近流出端的单元之一并具有朝向流入端延伸的自由端，接合臂可在加载状态和移动状态之间移动，在加载状态下，接合臂的取向基本上平行于所述接合臂与所述支架的所述纵向轴线形成第一角度的部分释放状态以及其中所述接合臂与所述支架的所述纵向轴线形成第二角度的完全释放状态，第一个角度大于第二个角度。

38. 发明申请

WO2017189530A3 EYELET, METHOD AND APPARATUS FOR BRAIDING MULTIPLE ENDS INTO A BRAIDED STRUCTURE 审中-公开
标题翻译：用于将多个端部编织成编织结构的眼睑，方法和设备
公开(公告)号：WO2017189530A3
公开(公告)日：2017-11-02
申请号：PCT/US2017/029338
申请日：2017-04-25
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： DUNNE, Kevin , DI GIACOMO, Mike
IPC分类号： D04C3/14 , D04C3/48
摘要： The present disclosure provides improved braiding methods that utilize a braiding eyelet (2) that may be housed on a carrier (3) in a braiding machine. The eyelet (2) includes a first side (4), a second side (6), and a flared opening (8) extending between the two sides (4, 6). The flared opening (8) includes a slot holder (12, 112) that has first and second slots (14, 16; 114, 116) sized and configured to allow a single end (18, 20; 124, 126, 128) to pass there-through such that when a group of two ends (18, 20) is used for the braiding, each individual end (18, 20) can pass through its own hole or slot (14, 16) to ensure that the end (18, 20) is locked in place and there is no space or clearance allowing them to cross over one another. Many embodiments of the present disclosure are suitable for constructing a medical device.
摘要翻译：本公开提供了改进的编织方法，其利用可以容纳在编织机中的载体（3）上的编织孔眼（2）。孔眼（2）包括第一侧面（4），第二侧面（6）和在两侧面（4,6）之间延伸的展开开口（8）。喇叭形开口（8）包括具有第一和第二狭槽（14,16; 114,116）的狭槽保持器（12,112），该第一和第二狭槽的尺寸和构造允许单个端部（18,20; 124,126,128）通过其中，使得当一组两端（18,20）用于编织时，每个单独的端部（18,20）可以穿过其自己的孔或狭槽（14,16）以确保端部（18,20） 18，20）被锁定到位，并且没有空间或间隙允许它们相互交叉。本公开的许多实施例适用于构建医疗设备。

39. 发明申请

WO2017165193A1 MULTIPLE THERMOCOUPLE ASSEMBLY WITH REDUCED WIRE COUNT 审中-公开
标题翻译：减少线数的多个热电偶组件
公开(公告)号：WO2017165193A1
公开(公告)日：2017-09-28
申请号：PCT/US2017/022746
申请日：2017-03-16
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： CURRAN, Timothy G. , TEGG, Troy T.
IPC分类号： A61B18/18 , A61B18/00
摘要： A multiple thermocouple assembly with a reduced wire count is configured for use in an ablation catheter tip. In at least one embodiment, the assembly comprises a first metal material comprising a plurality of junctions; a plurality of conductors comprising a second metal material, each conductor connected to the first metal material at one of the plurality of junctions; and a common conductor that is physically paired with at least one of the plurality of conductors at a corresponding common conductor junction such that the common conductor forms a thermocouple pair with each of the plurality of conductors.
摘要翻译：
具有减少线数的多个热电偶组件被配置用于消融导管尖端中。在至少一个实施例中，组件包括包含多个结的第一金属材料; 多个导体，所述多个导体包括第二金属材料，每个导体在所述多个接点中的一个接点处连接到所述第一金属材料; 以及公共导体，所述公共导体在相应的公共导体结处与所述多个导体中的至少一个导体物理配对，使得所述公共导体与所述多个导体中的每一个形成热电偶对。

40. 发明申请

WO2017127147A1 ATRAUMATIC COUPLING AND CATHETER EMPLOYING THE SAME 审中-公开
标题翻译：非接触式导尿管和使用同样的导尿管
公开(公告)号：WO2017127147A1
公开(公告)日：2017-07-27
申请号：PCT/US2016/061032
申请日：2016-11-09
申请人： ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： NEMEC, Linda K. , HAWKINSON, Neil D. , HENDRICKSON, Ryan , KNOCHENMUS, Matthew L.
IPC分类号： A61M25/00 , A61B18/14 , A61M25/09 , A61M39/12 , F16L7/02 , F16L25/14 , A61M39/10
CPC分类号： A61B5/0402 , A61B5/6852 , A61B18/1492 , A61B2018/1435 , A61M25/0014 , A61M25/0023 , A61M25/0069 , A61M25/0905 , A61M39/10 , A61M39/12 , A61M2039/1027
摘要： A catheter (10) includes a proximal shaft (14) and a distal shaft (16) having differing diameters; often, the distal shaft will have a smaller diameter than the proximal shaft. A coupling (18) joins the distal shaft to the proximal shaft. For example, a proximal portion (34) of the distal shaft can be inserted into the coupling through its distal end, while the proximal portion (32) of the coupling can be inserted into the proximal shaft through its distal end. To provide an atraumatic transition from the distal shaft to the proximal shaft, coupling can taper towards its distal end, for example by using a dome- or frustoconical-shape for the distal portion (30) of the coupling. The exterior of the coupling can be ribbed to facilitate bonding to the proximal shaft. The distal shaft can be formed into at least a partial loop having a fixed or variable radius of curvature.
摘要翻译：导管（10）包括具有不同直径的近侧轴（14）和远侧轴（16）;导管通常，远侧轴将具有比近侧轴更小的直径。联轴器（18）将远侧轴连接到近侧轴。例如，远侧轴的近侧部分（34）可以通过其远侧端插入到联接器中，而联接器的近侧部分（32）可以通过其远侧端插入近侧轴中。为了提供从远侧轴到近侧轴的防损伤过渡，联接件可朝其远侧端部渐缩，例如通过对联接件的远侧部分（30）使用圆顶或截头圆锥形状。联轴器的外部可以带肋，以便于与近端轴结合。远侧杆可以形成为具有固定或可变曲率半径的至少一个部分环。

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